Kajava, Andrey V.

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Authority KeyName Variants
5c0f91aa-41f1-43d0-b545-2d2caef6cb37
  • Kajava, Andrey V. (4)
Projects
Application of the EIIP/ISM bioinformatics platform in discovery of novel therapeutic targets and potential therapeutic molecules Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT) of Argentina [PICT-2015/3367]
Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT) of Argentina [PICT2017/1924] Carlsberg Distinguished Fellowship [CF18-0314]
Consejo Nacional de Ciencia y Tecnologia (CONACyT) [215503] COST Action BM1405 NGP-net, ELIXIR-IIB, Hungarian Academy of Sciences [LP2014-16], Hungarian Scientific Research Fund [OTKA K 108798], AIRC Research Fellowship, Spanish Ministerio de Educacion Cultura i Deporte PhD Fellowship, Mexican National Council for Science and Technology (CONACYT) [215503], Grant PortoNeuroDRIve'i3S - Norte Portugal Regional Operational Programme (NORTE), under the PORTUGAL Partnership Agreement, through the European Regional Development Fund (ERDF), Direction Generale des Armees, Aix-Marseille University PhD Fellowship, OTKA Grant [PD-OTKA 108772], French Ministry of National Education, Research and Technology PhD Fellowship, ICREAAcademia Award, Odysseus Grant from Research Foundation Flanders (FWO) [G.0029.12], AIRC IG Grant [17753], Italian Ministry of Health [GR-2011-02347754, GR-2011-02346845], Swedish Research Council Grant [VR-NT 2012-5046]
Danmarks Grundforskningsfond [DNRF125] Elixir-GR, Action 'Reinforcement of the Research and Innovation Infrastructure', Operational Programme 'Competitiveness, Entrepreneurship and Innovation' [NSRF]
European Regional Development Fund [POCI01-0145-FEDER-029221] European Regional Development Fund [POCI-01-0145-FEDER-031173]
European Union's Horizon 2020 research and innovation programme [778247]. Funding for open access charge: European Union's Horizon 2020 research and innovation programme [778247] H2020-MSCA-RISE project REFRACT [GA No. 823886]
Hungarian Academy of Sciences [LP2014-18] Hungarian Academy of Sciences [PREMIUM-2017-48]
Hungarian National Research, Development, and Innovation Office (NKFIH) [FK-128133] ICREA
Molecular determinants for tumor marker design Italian Ministry of Health Young Investigator Grant [GR-2011-02347754]
Ministerio de Economia y Competitividad (MINECO) [BIO2016-78310-R] National Institute of Allergy and Infectious Diseases [Research Grant 1R01AI12123701]
National Research, Development and Innovation Office [K-125340] Orszagos Tudomanyos Kutatasi Alapprogramok (OTKA) [K108798]
Orszagos Tudomanyos Kutatasi Alapprogramok (OTKA) [K124670] Portuguese Foundation for Science and Technology
Research Foundation Flanders (FWO) [G.0328.16N] Swedish Research Council [2016-03798]

Author's Bibliography

Tally-2.0: upgraded validator of tandem repeat detection in protein sequences

Perović, Vladimir R.; Leclercq, Jeremy Y; Šumonja, Neven; Richard, Francois D; Veljković, Nevena V.; Kajava, Andrey V.

(2020)

TY  - JOUR
AU  - Perović, Vladimir R.
AU  - Leclercq, Jeremy Y
AU  - Šumonja, Neven
AU  - Richard, Francois D
AU  - Veljković, Nevena V.
AU  - Kajava, Andrey V.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8997
AB  - Motivation: Proteins containing tandem repeats (TRs) are abundant, frequently fold in elongated non-globular structures and perform vital functions. A number of computational tools have been developed to detect TRs in protein sequences. A blurred boundary between imperfect TR motifs and non-repetitive sequences gave rise to necessity to validate the detected TRs. Results: Tally-2.0 is a scoring tool based on a machine learning (ML) approach, which allows to validate the results of TR detection. It was upgraded by using improved training datasets and additional ML features. Tally-2.0 performs at a level of 93% sensitivity, 83% specificity and an area under the receiver operating characteristic curve of 95%.
T2  - Bioinformatics
T1  - Tally-2.0: upgraded validator of tandem repeat detection in protein sequences
VL  - 36
IS  - 10
SP  - 3260
EP  - 3262
DO  - 10.1093/bioinformatics/btaa121
ER  - 
@article{
author = "Perović, Vladimir R. and Leclercq, Jeremy Y and Šumonja, Neven and Richard, Francois D and Veljković, Nevena V. and Kajava, Andrey V.",
year = "2020",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/8997",
abstract = "Motivation: Proteins containing tandem repeats (TRs) are abundant, frequently fold in elongated non-globular structures and perform vital functions. A number of computational tools have been developed to detect TRs in protein sequences. A blurred boundary between imperfect TR motifs and non-repetitive sequences gave rise to necessity to validate the detected TRs. Results: Tally-2.0 is a scoring tool based on a machine learning (ML) approach, which allows to validate the results of TR detection. It was upgraded by using improved training datasets and additional ML features. Tally-2.0 performs at a level of 93% sensitivity, 83% specificity and an area under the receiver operating characteristic curve of 95%.",
journal = "Bioinformatics",
title = "Tally-2.0: upgraded validator of tandem repeat detection in protein sequences",
volume = "36",
number = "10",
pages = "3260-3262",
doi = "10.1093/bioinformatics/btaa121"
}
Perović, V. R., Leclercq, J. Y., Šumonja, N., Richard, F. D., Veljković, N. V.,& Kajava, A. V. (2020). Tally-2.0: upgraded validator of tandem repeat detection in protein sequences.
Bioinformatics, 36(10), 3260-3262.
https://doi.org/10.1093/bioinformatics/btaa121
Perović VR, Leclercq JY, Šumonja N, Richard FD, Veljković NV, Kajava AV. Tally-2.0: upgraded validator of tandem repeat detection in protein sequences. Bioinformatics. 2020;36(10):3260-3262
Perović Vladimir R., Leclercq Jeremy Y, Šumonja Neven, Richard Francois D, Veljković Nevena V., Kajava Andrey V., "Tally-2.0: upgraded validator of tandem repeat detection in protein sequences" Bioinformatics, 36, no. 10 (2020):3260-3262,
https://doi.org/10.1093/bioinformatics/btaa121 .
2
1
1
1

DisProt: intrinsic protein disorder annotation in 2020

Hatos, András; Hajdu-Soltész, Borbála; Monzon, Alexander M; Palopoli, Nicolas; Álvarez, Lucía; Aykac-Fas, Burcu; Bassot, Claudio; Benítez, Guillermo I; Bevilacqua, Martina; Chasapi, Anastasia; Chemes, Lucia; Davey, Norman E; Davidović, Radoslav S.; Dunker, A Keith; Elofsson, Arne; Gobeill, Julien; Foutel, Nicolás S González; Sudha, Govindarajan; Guharoy, Mainak; Horvath, Tamas; Iglesias, Valentin; Kajava, Andrey V.; Kovacs, Orsolya P; Lamb, John; Lambrughi, Matteo; Lazar, Tamas; Leclercq, Jeremy Y; Leonardi, Emanuela; Macedo-Ribeiro, Sandra; Macossay-Castillo, Mauricio; Maiani, Emiliano; Manso, José A; Marino-Buslje, Cristina; Martínez-Pérez, Elizabeth; Mészáros, Bálint; Mičetić, Ivan; Minervini, Giovanni; Murvai, Nikoletta; Necci, Marco; Ouzounis, Christos A; Pajkos, Mátyás; Paladin, Lisanna; Pancsa, Rita; Papaleo, Elena; Parisi, Gustavo; Pasche, Emilie; Barbosa Pereira, Pedro J; Promponas, Vasilis J; Pujols, Jordi; Quaglia, Federica; Ruch, Patrick; Salvatore, Marco; Schad, Eva; Szabo, Beata; Szaniszló, Tamás; Tamana, Stella; Tantos, Agnes; Veljković, Nevena V.; Ventura, Salvador; Vranken, Wim; Dosztányi, Zsuzsanna; Tompa, Peter; Tosatto, Silvio C E; Piovesan, Damiano

(2019)

TY  - JOUR
AU  - Hatos, András
AU  - Hajdu-Soltész, Borbála
AU  - Monzon, Alexander M
AU  - Palopoli, Nicolas
AU  - Álvarez, Lucía
AU  - Aykac-Fas, Burcu
AU  - Bassot, Claudio
AU  - Benítez, Guillermo I
AU  - Bevilacqua, Martina
AU  - Chasapi, Anastasia
AU  - Chemes, Lucia
AU  - Davey, Norman E
AU  - Davidović, Radoslav S.
AU  - Dunker, A Keith
AU  - Elofsson, Arne
AU  - Gobeill, Julien
AU  - Foutel, Nicolás S González
AU  - Sudha, Govindarajan
AU  - Guharoy, Mainak
AU  - Horvath, Tamas
AU  - Iglesias, Valentin
AU  - Kajava, Andrey V.
AU  - Kovacs, Orsolya P
AU  - Lamb, John
AU  - Lambrughi, Matteo
AU  - Lazar, Tamas
AU  - Leclercq, Jeremy Y
AU  - Leonardi, Emanuela
AU  - Macedo-Ribeiro, Sandra
AU  - Macossay-Castillo, Mauricio
AU  - Maiani, Emiliano
AU  - Manso, José A
AU  - Marino-Buslje, Cristina
AU  - Martínez-Pérez, Elizabeth
AU  - Mészáros, Bálint
AU  - Mičetić, Ivan
AU  - Minervini, Giovanni
AU  - Murvai, Nikoletta
AU  - Necci, Marco
AU  - Ouzounis, Christos A
AU  - Pajkos, Mátyás
AU  - Paladin, Lisanna
AU  - Pancsa, Rita
AU  - Papaleo, Elena
AU  - Parisi, Gustavo
AU  - Pasche, Emilie
AU  - Barbosa Pereira, Pedro J
AU  - Promponas, Vasilis J
AU  - Pujols, Jordi
AU  - Quaglia, Federica
AU  - Ruch, Patrick
AU  - Salvatore, Marco
AU  - Schad, Eva
AU  - Szabo, Beata
AU  - Szaniszló, Tamás
AU  - Tamana, Stella
AU  - Tantos, Agnes
AU  - Veljković, Nevena V.
AU  - Ventura, Salvador
AU  - Vranken, Wim
AU  - Dosztányi, Zsuzsanna
AU  - Tompa, Peter
AU  - Tosatto, Silvio C E
AU  - Piovesan, Damiano
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8799
AB  - The Database of Protein Disorder (DisProt, URL: https://disprot.org) provides manually curated annotations of intrinsically disordered proteins from the literature. Here we report recent developments with DisProt (version 8), including the doubling of protein entries, a new disorder ontology, improvements of the annotation format and a completely new website. The website includes a redesigned graphical interface, a better search engine, a clearer API for programmatic access and a new annotation interface that integrates text mining technologies. The new entry format provides a greater flexibility, simplifies maintenance and allows the capture of more information from the literature. The new disorder ontology has been formalized and made interoperable by adopting the OWL format, as well as its structure and term definitions have been improved. The new annotation interface has made the curation process faster and more effective. We recently showed that new DisProt annotations can be effectively used to train and validate disorder predictors. We believe the growth of DisProt will accelerate, contributing to the improvement of function and disorder predictors and therefore to illuminate the ‘dark’ proteome.
T2  - Nucleic Acids Research
T1  - DisProt: intrinsic protein disorder annotation in 2020
VL  - 48
IS  - D1
SP  - D269
EP  - D276
DO  - 10.1093/nar/gkz975
ER  - 
@article{
author = "Hatos, András and Hajdu-Soltész, Borbála and Monzon, Alexander M and Palopoli, Nicolas and Álvarez, Lucía and Aykac-Fas, Burcu and Bassot, Claudio and Benítez, Guillermo I and Bevilacqua, Martina and Chasapi, Anastasia and Chemes, Lucia and Davey, Norman E and Davidović, Radoslav S. and Dunker, A Keith and Elofsson, Arne and Gobeill, Julien and Foutel, Nicolás S González and Sudha, Govindarajan and Guharoy, Mainak and Horvath, Tamas and Iglesias, Valentin and Kajava, Andrey V. and Kovacs, Orsolya P and Lamb, John and Lambrughi, Matteo and Lazar, Tamas and Leclercq, Jeremy Y and Leonardi, Emanuela and Macedo-Ribeiro, Sandra and Macossay-Castillo, Mauricio and Maiani, Emiliano and Manso, José A and Marino-Buslje, Cristina and Martínez-Pérez, Elizabeth and Mészáros, Bálint and Mičetić, Ivan and Minervini, Giovanni and Murvai, Nikoletta and Necci, Marco and Ouzounis, Christos A and Pajkos, Mátyás and Paladin, Lisanna and Pancsa, Rita and Papaleo, Elena and Parisi, Gustavo and Pasche, Emilie and Barbosa Pereira, Pedro J and Promponas, Vasilis J and Pujols, Jordi and Quaglia, Federica and Ruch, Patrick and Salvatore, Marco and Schad, Eva and Szabo, Beata and Szaniszló, Tamás and Tamana, Stella and Tantos, Agnes and Veljković, Nevena V. and Ventura, Salvador and Vranken, Wim and Dosztányi, Zsuzsanna and Tompa, Peter and Tosatto, Silvio C E and Piovesan, Damiano",
year = "2019",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/8799",
abstract = "The Database of Protein Disorder (DisProt, URL: https://disprot.org) provides manually curated annotations of intrinsically disordered proteins from the literature. Here we report recent developments with DisProt (version 8), including the doubling of protein entries, a new disorder ontology, improvements of the annotation format and a completely new website. The website includes a redesigned graphical interface, a better search engine, a clearer API for programmatic access and a new annotation interface that integrates text mining technologies. The new entry format provides a greater flexibility, simplifies maintenance and allows the capture of more information from the literature. The new disorder ontology has been formalized and made interoperable by adopting the OWL format, as well as its structure and term definitions have been improved. The new annotation interface has made the curation process faster and more effective. We recently showed that new DisProt annotations can be effectively used to train and validate disorder predictors. We believe the growth of DisProt will accelerate, contributing to the improvement of function and disorder predictors and therefore to illuminate the ‘dark’ proteome.",
journal = "Nucleic Acids Research",
title = "DisProt: intrinsic protein disorder annotation in 2020",
volume = "48",
number = "D1",
pages = "D269-D276",
doi = "10.1093/nar/gkz975"
}
Hatos, A., Hajdu-Soltész, B., Monzon, A. M., Palopoli, N., Álvarez, L., Aykac-Fas, B., Bassot, C., Benítez, G. I., Bevilacqua, M., Chasapi, A., Chemes, L., Davey, N. E., Davidović, R. S., Dunker, A. K., Elofsson, A., Gobeill, J., Foutel, N. S. G., Sudha, G., Guharoy, M., Horvath, T., Iglesias, V., Kajava, A. V., Kovacs, O. P., Lamb, J., Lambrughi, M., Lazar, T., Leclercq, J. Y., Leonardi, E., Macedo-Ribeiro, S., Macossay-Castillo, M., Maiani, E., Manso, J. A., Marino-Buslje, C., Martínez-Pérez, E., Mészáros, B., Mičetić, I., Minervini, G., Murvai, N., Necci, M., Ouzounis, C. A., Pajkos, M., Paladin, L., Pancsa, R., Papaleo, E., Parisi, G., Pasche, E., Barbosa Pereira, P. J., Promponas, V. J., Pujols, J., Quaglia, F., Ruch, P., Salvatore, M., Schad, E., Szabo, B., Szaniszló, T., Tamana, S., Tantos, A., Veljković, N. V., Ventura, S., Vranken, W., Dosztányi, Z., Tompa, P., Tosatto, S. C. E.,& Piovesan, D. (2019). DisProt: intrinsic protein disorder annotation in 2020.
Nucleic Acids Research, 48(D1), D269-D276.
https://doi.org/10.1093/nar/gkz975
Hatos A, Hajdu-Soltész B, Monzon AM, Palopoli N, Álvarez L, Aykac-Fas B, Bassot C, Benítez GI, Bevilacqua M, Chasapi A, Chemes L, Davey NE, Davidović RS, Dunker AK, Elofsson A, Gobeill J, Foutel NSG, Sudha G, Guharoy M, Horvath T, Iglesias V, Kajava AV, Kovacs OP, Lamb J, Lambrughi M, Lazar T, Leclercq JY, Leonardi E, Macedo-Ribeiro S, Macossay-Castillo M, Maiani E, Manso JA, Marino-Buslje C, Martínez-Pérez E, Mészáros B, Mičetić I, Minervini G, Murvai N, Necci M, Ouzounis CA, Pajkos M, Paladin L, Pancsa R, Papaleo E, Parisi G, Pasche E, Barbosa Pereira PJ, Promponas VJ, Pujols J, Quaglia F, Ruch P, Salvatore M, Schad E, Szabo B, Szaniszló T, Tamana S, Tantos A, Veljković NV, Ventura S, Vranken W, Dosztányi Z, Tompa P, Tosatto SCE, Piovesan D. DisProt: intrinsic protein disorder annotation in 2020. Nucleic Acids Research. 2019;48(D1):D269-D276
Hatos András, Hajdu-Soltész Borbála, Monzon Alexander M, Palopoli Nicolas, Álvarez Lucía, Aykac-Fas Burcu, Bassot Claudio, Benítez Guillermo I, Bevilacqua Martina, Chasapi Anastasia, Chemes Lucia, Davey Norman E, Davidović Radoslav S., Dunker A Keith, Elofsson Arne, Gobeill Julien, Foutel Nicolás S González, Sudha Govindarajan, Guharoy Mainak, Horvath Tamas, Iglesias Valentin, Kajava Andrey V., Kovacs Orsolya P, Lamb John, Lambrughi Matteo, Lazar Tamas, Leclercq Jeremy Y, Leonardi Emanuela, Macedo-Ribeiro Sandra, Macossay-Castillo Mauricio, Maiani Emiliano, Manso José A, Marino-Buslje Cristina, Martínez-Pérez Elizabeth, Mészáros Bálint, Mičetić Ivan, Minervini Giovanni, Murvai Nikoletta, Necci Marco, Ouzounis Christos A, Pajkos Mátyás, Paladin Lisanna, Pancsa Rita, Papaleo Elena, Parisi Gustavo, Pasche Emilie, Barbosa Pereira Pedro J, Promponas Vasilis J, Pujols Jordi, Quaglia Federica, Ruch Patrick, Salvatore Marco, Schad Eva, Szabo Beata, Szaniszló Tamás, Tamana Stella, Tantos Agnes, Veljković Nevena V., Ventura Salvador, Vranken Wim, Dosztányi Zsuzsanna, Tompa Peter, Tosatto Silvio C E, Piovesan Damiano, "DisProt: intrinsic protein disorder annotation in 2020" Nucleic Acids Research, 48, no. D1 (2019):D269-D276,
https://doi.org/10.1093/nar/gkz975 .
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65
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35

DisProt 7.0: a major update of the database of disordered proteins

Piovesan, Damiano; Tabaro, Francesco; Micetic, Ivan; Necci, Marco; Quaglia, Federica; Oldfield, Christopher J.; Aspromonte, Maria Cristina; Davey, Norman E.; Davidović, Radoslav S.; Dosztanyi, Zsuzsanna; Elofsson, Arne; Gasparini, Alessandra; Hatos, Andras; Kajava, Andrey V.; Kalmar, Lajos; Leonardi, Emanuela; Lazar, Tamas; Macedo-Ribeiro, Sandra; Macossay-Castillo, Mauricio; Meszaros, Attila; Minervini, Giovanni; Murvai, Nikoletta; Pujols, Jordi; Roche, Daniel B.; Salladini, Edoardo; Schad, Eva; Schramm, Antoine; Szabo, Beata; Tantos, Agnes; Tonello, Fiorella; Tsirigos, Konstantinos D.; Veljković, Nevena V.; Ventura, Salvador; Vranken, Wim; Warholm, Per; Uversky, Vladimir N.; Dunker, A. Keith; Longhi, Sonia; Tompa, Peter; Tosatto, Silvio C. E.

(2017)

TY  - JOUR
AU  - Piovesan, Damiano
AU  - Tabaro, Francesco
AU  - Micetic, Ivan
AU  - Necci, Marco
AU  - Quaglia, Federica
AU  - Oldfield, Christopher J.
AU  - Aspromonte, Maria Cristina
AU  - Davey, Norman E.
AU  - Davidović, Radoslav S.
AU  - Dosztanyi, Zsuzsanna
AU  - Elofsson, Arne
AU  - Gasparini, Alessandra
AU  - Hatos, Andras
AU  - Kajava, Andrey V.
AU  - Kalmar, Lajos
AU  - Leonardi, Emanuela
AU  - Lazar, Tamas
AU  - Macedo-Ribeiro, Sandra
AU  - Macossay-Castillo, Mauricio
AU  - Meszaros, Attila
AU  - Minervini, Giovanni
AU  - Murvai, Nikoletta
AU  - Pujols, Jordi
AU  - Roche, Daniel B.
AU  - Salladini, Edoardo
AU  - Schad, Eva
AU  - Schramm, Antoine
AU  - Szabo, Beata
AU  - Tantos, Agnes
AU  - Tonello, Fiorella
AU  - Tsirigos, Konstantinos D.
AU  - Veljković, Nevena V.
AU  - Ventura, Salvador
AU  - Vranken, Wim
AU  - Warholm, Per
AU  - Uversky, Vladimir N.
AU  - Dunker, A. Keith
AU  - Longhi, Sonia
AU  - Tompa, Peter
AU  - Tosatto, Silvio C. E.
PY  - 2017
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1464
AB  - The Database of Protein Disorder (DisProt, URL: www.disprot.org) has been significantly updated and upgraded since its last major renewal in 2007. The current release holds information on more than 800 entries of IDPs/IDRs, i.e. intrinsically disordered proteins or regions that exist and function without a well-defined three-dimensional structure. We have re-curated previous entries to purge DisProt from conflicting cases, and also upgraded the functional classification scheme to reflect continuous advance in the field in the past 10 years or so. We define IDPs as proteins that are disordered along their entire sequence, i.e. entirely lack structural elements, and IDRs as regions that are at least five consecutive residues without well-defined structure. We base our assessment of disorder strictly on experimental evidence, such as X-ray crystallography and nuclear magnetic resonance ( primary techniques) and a broad range of other experimental approaches (secondary techniques). Confident and ambiguous annotations are highlighted separately. DisProt 7.0 presents classified knowledge regarding the experimental characterization and functional annotations of IDPs/IDRs, and is intended to provide an invaluable resource for the research community for a better understanding structural disorder and for developing better computational tools for studying disordered proteins.
T2  - Nucleic Acids Research
T1  - DisProt 7.0: a major update of the database of disordered proteins
VL  - 45
IS  - D1
SP  - D219
EP  - D227
DO  - 10.1093/nar/gkw1056
ER  - 
@article{
author = "Piovesan, Damiano and Tabaro, Francesco and Micetic, Ivan and Necci, Marco and Quaglia, Federica and Oldfield, Christopher J. and Aspromonte, Maria Cristina and Davey, Norman E. and Davidović, Radoslav S. and Dosztanyi, Zsuzsanna and Elofsson, Arne and Gasparini, Alessandra and Hatos, Andras and Kajava, Andrey V. and Kalmar, Lajos and Leonardi, Emanuela and Lazar, Tamas and Macedo-Ribeiro, Sandra and Macossay-Castillo, Mauricio and Meszaros, Attila and Minervini, Giovanni and Murvai, Nikoletta and Pujols, Jordi and Roche, Daniel B. and Salladini, Edoardo and Schad, Eva and Schramm, Antoine and Szabo, Beata and Tantos, Agnes and Tonello, Fiorella and Tsirigos, Konstantinos D. and Veljković, Nevena V. and Ventura, Salvador and Vranken, Wim and Warholm, Per and Uversky, Vladimir N. and Dunker, A. Keith and Longhi, Sonia and Tompa, Peter and Tosatto, Silvio C. E.",
year = "2017",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/1464",
abstract = "The Database of Protein Disorder (DisProt, URL: www.disprot.org) has been significantly updated and upgraded since its last major renewal in 2007. The current release holds information on more than 800 entries of IDPs/IDRs, i.e. intrinsically disordered proteins or regions that exist and function without a well-defined three-dimensional structure. We have re-curated previous entries to purge DisProt from conflicting cases, and also upgraded the functional classification scheme to reflect continuous advance in the field in the past 10 years or so. We define IDPs as proteins that are disordered along their entire sequence, i.e. entirely lack structural elements, and IDRs as regions that are at least five consecutive residues without well-defined structure. We base our assessment of disorder strictly on experimental evidence, such as X-ray crystallography and nuclear magnetic resonance ( primary techniques) and a broad range of other experimental approaches (secondary techniques). Confident and ambiguous annotations are highlighted separately. DisProt 7.0 presents classified knowledge regarding the experimental characterization and functional annotations of IDPs/IDRs, and is intended to provide an invaluable resource for the research community for a better understanding structural disorder and for developing better computational tools for studying disordered proteins.",
journal = "Nucleic Acids Research",
title = "DisProt 7.0: a major update of the database of disordered proteins",
volume = "45",
number = "D1",
pages = "D219-D227",
doi = "10.1093/nar/gkw1056"
}
Piovesan, D., Tabaro, F., Micetic, I., Necci, M., Quaglia, F., Oldfield, C. J., Aspromonte, M. C., Davey, N. E., Davidović, R. S., Dosztanyi, Z., Elofsson, A., Gasparini, A., Hatos, A., Kajava, A. V., Kalmar, L., Leonardi, E., Lazar, T., Macedo-Ribeiro, S., Macossay-Castillo, M., Meszaros, A., Minervini, G., Murvai, N., Pujols, J., Roche, D. B., Salladini, E., Schad, E., Schramm, A., Szabo, B., Tantos, A., Tonello, F., Tsirigos, K. D., Veljković, N. V., Ventura, S., Vranken, W., Warholm, P., Uversky, V. N., Dunker, A. K., Longhi, S., Tompa, P.,& Tosatto, S. C. E. (2017). DisProt 7.0: a major update of the database of disordered proteins.
Nucleic Acids Research, 45(D1), D219-D227.
https://doi.org/10.1093/nar/gkw1056
Piovesan D, Tabaro F, Micetic I, Necci M, Quaglia F, Oldfield CJ, Aspromonte MC, Davey NE, Davidović RS, Dosztanyi Z, Elofsson A, Gasparini A, Hatos A, Kajava AV, Kalmar L, Leonardi E, Lazar T, Macedo-Ribeiro S, Macossay-Castillo M, Meszaros A, Minervini G, Murvai N, Pujols J, Roche DB, Salladini E, Schad E, Schramm A, Szabo B, Tantos A, Tonello F, Tsirigos KD, Veljković NV, Ventura S, Vranken W, Warholm P, Uversky VN, Dunker AK, Longhi S, Tompa P, Tosatto SCE. DisProt 7.0: a major update of the database of disordered proteins. Nucleic Acids Research. 2017;45(D1):D219-D227
Piovesan Damiano, Tabaro Francesco, Micetic Ivan, Necci Marco, Quaglia Federica, Oldfield Christopher J., Aspromonte Maria Cristina, Davey Norman E., Davidović Radoslav S., Dosztanyi Zsuzsanna, Elofsson Arne, Gasparini Alessandra, Hatos Andras, Kajava Andrey V., Kalmar Lajos, Leonardi Emanuela, Lazar Tamas, Macedo-Ribeiro Sandra, Macossay-Castillo Mauricio, Meszaros Attila, Minervini Giovanni, Murvai Nikoletta, Pujols Jordi, Roche Daniel B., Salladini Edoardo, Schad Eva, Schramm Antoine, Szabo Beata, Tantos Agnes, Tonello Fiorella, Tsirigos Konstantinos D., Veljković Nevena V., Ventura Salvador, Vranken Wim, Warholm Per, Uversky Vladimir N., Dunker A. Keith, Longhi Sonia, Tompa Peter, Tosatto Silvio C. E., "DisProt 7.0: a major update of the database of disordered proteins" Nucleic Acids Research, 45, no. D1 (2017):D219-D227,
https://doi.org/10.1093/nar/gkw1056 .
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DisProt 7.0: a major update of the database of disordered proteins (vol 45, pg D219, 2017)

Piovesan, Damiano; Tabaro, Francesco; Micetic, Ivan; Necci, Marco; Quaglia, Federica; Oldfield, Christopher J.; Aspromonte, Maria Cristina; Davey, Norman E.; Davidović, Radoslav S.; Dosztanyi, Zsuzsanna; Elofsson, Arne; Gasparini, Alessandra; Hatos, Andras; Kajava, Andrey V.; Kalmar, Lajos; Leonardi, Emanuela; Lazar, Tamas; Macedo-Ribeiro, Sandra; Macossay-Castillo, Mauricio; Meszaros, Attila; Minervini, Giovanni; Murvai, Nikoletta; Pujols, Jordi; Roche, Daniel B.; Salladini, Edoardo; Schad, Eva; Schramm, Antoine; Szabo, Beata; Tantos, Agnes; Tonello, Fiorella; Tsirigos, Konstantinos D.; Veljković, Nevena V.; Ventura, Salvador; Vranken, Wim; Warholm, Per; Uversky, Vladimir N.; Dunker, A. Keith; Longhi, Sonia; Tompa, Peter; Tosatto, Silvio C. E.

(2017)

TY  - BOOK
AU  - Piovesan, Damiano
AU  - Tabaro, Francesco
AU  - Micetic, Ivan
AU  - Necci, Marco
AU  - Quaglia, Federica
AU  - Oldfield, Christopher J.
AU  - Aspromonte, Maria Cristina
AU  - Davey, Norman E.
AU  - Davidović, Radoslav S.
AU  - Dosztanyi, Zsuzsanna
AU  - Elofsson, Arne
AU  - Gasparini, Alessandra
AU  - Hatos, Andras
AU  - Kajava, Andrey V.
AU  - Kalmar, Lajos
AU  - Leonardi, Emanuela
AU  - Lazar, Tamas
AU  - Macedo-Ribeiro, Sandra
AU  - Macossay-Castillo, Mauricio
AU  - Meszaros, Attila
AU  - Minervini, Giovanni
AU  - Murvai, Nikoletta
AU  - Pujols, Jordi
AU  - Roche, Daniel B.
AU  - Salladini, Edoardo
AU  - Schad, Eva
AU  - Schramm, Antoine
AU  - Szabo, Beata
AU  - Tantos, Agnes
AU  - Tonello, Fiorella
AU  - Tsirigos, Konstantinos D.
AU  - Veljković, Nevena V.
AU  - Ventura, Salvador
AU  - Vranken, Wim
AU  - Warholm, Per
AU  - Uversky, Vladimir N.
AU  - Dunker, A. Keith
AU  - Longhi, Sonia
AU  - Tompa, Peter
AU  - Tosatto, Silvio C. E.
PY  - 2017
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1465
T2  - Nucleic Acids Research
T1  - DisProt 7.0: a major update of the database of disordered proteins (vol 45, pg D219, 2017)
VL  - 45
IS  - D1
SP  - D1123
EP  - D1124
DO  - 10.1093/nar/gkw1279
ER  - 
@book{
author = "Piovesan, Damiano and Tabaro, Francesco and Micetic, Ivan and Necci, Marco and Quaglia, Federica and Oldfield, Christopher J. and Aspromonte, Maria Cristina and Davey, Norman E. and Davidović, Radoslav S. and Dosztanyi, Zsuzsanna and Elofsson, Arne and Gasparini, Alessandra and Hatos, Andras and Kajava, Andrey V. and Kalmar, Lajos and Leonardi, Emanuela and Lazar, Tamas and Macedo-Ribeiro, Sandra and Macossay-Castillo, Mauricio and Meszaros, Attila and Minervini, Giovanni and Murvai, Nikoletta and Pujols, Jordi and Roche, Daniel B. and Salladini, Edoardo and Schad, Eva and Schramm, Antoine and Szabo, Beata and Tantos, Agnes and Tonello, Fiorella and Tsirigos, Konstantinos D. and Veljković, Nevena V. and Ventura, Salvador and Vranken, Wim and Warholm, Per and Uversky, Vladimir N. and Dunker, A. Keith and Longhi, Sonia and Tompa, Peter and Tosatto, Silvio C. E.",
year = "2017",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/1465",
journal = "Nucleic Acids Research",
title = "DisProt 7.0: a major update of the database of disordered proteins (vol 45, pg D219, 2017)",
volume = "45",
number = "D1",
pages = "D1123-D1124",
doi = "10.1093/nar/gkw1279"
}
Piovesan, D., Tabaro, F., Micetic, I., Necci, M., Quaglia, F., Oldfield, C. J., Aspromonte, M. C., Davey, N. E., Davidović, R. S., Dosztanyi, Z., Elofsson, A., Gasparini, A., Hatos, A., Kajava, A. V., Kalmar, L., Leonardi, E., Lazar, T., Macedo-Ribeiro, S., Macossay-Castillo, M., Meszaros, A., Minervini, G., Murvai, N., Pujols, J., Roche, D. B., Salladini, E., Schad, E., Schramm, A., Szabo, B., Tantos, A., Tonello, F., Tsirigos, K. D., Veljković, N. V., Ventura, S., Vranken, W., Warholm, P., Uversky, V. N., Dunker, A. K., Longhi, S., Tompa, P.,& Tosatto, S. C. E. (2017). DisProt 7.0: a major update of the database of disordered proteins (vol 45, pg D219, 2017).
Nucleic Acids Research, 45(D1), D1123-D1124.
https://doi.org/10.1093/nar/gkw1279
Piovesan D, Tabaro F, Micetic I, Necci M, Quaglia F, Oldfield CJ, Aspromonte MC, Davey NE, Davidović RS, Dosztanyi Z, Elofsson A, Gasparini A, Hatos A, Kajava AV, Kalmar L, Leonardi E, Lazar T, Macedo-Ribeiro S, Macossay-Castillo M, Meszaros A, Minervini G, Murvai N, Pujols J, Roche DB, Salladini E, Schad E, Schramm A, Szabo B, Tantos A, Tonello F, Tsirigos KD, Veljković NV, Ventura S, Vranken W, Warholm P, Uversky VN, Dunker AK, Longhi S, Tompa P, Tosatto SCE. DisProt 7.0: a major update of the database of disordered proteins (vol 45, pg D219, 2017). Nucleic Acids Research. 2017;45(D1):D1123-D1124
Piovesan Damiano, Tabaro Francesco, Micetic Ivan, Necci Marco, Quaglia Federica, Oldfield Christopher J., Aspromonte Maria Cristina, Davey Norman E., Davidović Radoslav S., Dosztanyi Zsuzsanna, Elofsson Arne, Gasparini Alessandra, Hatos Andras, Kajava Andrey V., Kalmar Lajos, Leonardi Emanuela, Lazar Tamas, Macedo-Ribeiro Sandra, Macossay-Castillo Mauricio, Meszaros Attila, Minervini Giovanni, Murvai Nikoletta, Pujols Jordi, Roche Daniel B., Salladini Edoardo, Schad Eva, Schramm Antoine, Szabo Beata, Tantos Agnes, Tonello Fiorella, Tsirigos Konstantinos D., Veljković Nevena V., Ventura Salvador, Vranken Wim, Warholm Per, Uversky Vladimir N., Dunker A. Keith, Longhi Sonia, Tompa Peter, Tosatto Silvio C. E., "DisProt 7.0: a major update of the database of disordered proteins (vol 45, pg D219, 2017)" Nucleic Acids Research, 45, no. D1 (2017):D1123-D1124,
https://doi.org/10.1093/nar/gkw1279 .
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