TY  - JOUR
AU  - Popsavin, M
AU  - Torovic, L
AU  - Spaic, S
AU  - Stankov, S
AU  - Kapor, Agneš
AU  - Tomić, Zoran D.
AU  - Popsavin, V
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2494
AB  - 3(5)-Carboxamido-4-(beta-D-ribofuranosyl)pyrazoles bearing 2-benzamido (15) and 3-mesyloxy (29) isosteric groups, as well as the tetrazole C-nucleosides with 2-benzamido-2-deoxy-beta-D-ribofuranose (19) and 3-azido-3-deoxy-beta-D-xylofuranose (36) as sugar segments, have been synthesized starting from D-glucose, by utilizing the 2,5-anhydro-D-glucose ethylene acetal derivatives 1 and 20 as divergent intermediates. The C-nucleosides 15 and 36 were shown to be moderate inhibitors of the in vitro growth of both N2a and BHK 21 tumour cell lines, whereas 29 showed a selective, although not potent cytotoxic activity against N2a cells. Compound 29 also showed a moderate in vitro antiviral activity towards the rabies virus. (C) 2002 Elsevier Science Ltd. All rights reserved.
T2  - Tetrahedron
T1  - Synthesis and biological evaluation of new pyrazole- and tetrazole-related C-nucleosides with modified sugar moieties
VL  - 58
IS  - 3
SP  - 569
EP  - 580
DO  - 10.1016/S0040-4020(01)01126-7
ER  - 

@article{
author = "Popsavin, M and Torovic, L and Spaic, S and Stankov, S and Kapor, Agneš and Tomić, Zoran D. and Popsavin, V",
year = "2002",
abstract = "3(5)-Carboxamido-4-(beta-D-ribofuranosyl)pyrazoles bearing 2-benzamido (15) and 3-mesyloxy (29) isosteric groups, as well as the tetrazole C-nucleosides with 2-benzamido-2-deoxy-beta-D-ribofuranose (19) and 3-azido-3-deoxy-beta-D-xylofuranose (36) as sugar segments, have been synthesized starting from D-glucose, by utilizing the 2,5-anhydro-D-glucose ethylene acetal derivatives 1 and 20 as divergent intermediates. The C-nucleosides 15 and 36 were shown to be moderate inhibitors of the in vitro growth of both N2a and BHK 21 tumour cell lines, whereas 29 showed a selective, although not potent cytotoxic activity against N2a cells. Compound 29 also showed a moderate in vitro antiviral activity towards the rabies virus. (C) 2002 Elsevier Science Ltd. All rights reserved.",
journal = "Tetrahedron",
title = "Synthesis and biological evaluation of new pyrazole- and tetrazole-related C-nucleosides with modified sugar moieties",
volume = "58",
number = "3",
pages = "569-580",
doi = "10.1016/S0040-4020(01)01126-7"
}

Popsavin, M., Torovic, L., Spaic, S., Stankov, S., Kapor, A., Tomić, Z. D.,& Popsavin, V.. (2002). Synthesis and biological evaluation of new pyrazole- and tetrazole-related C-nucleosides with modified sugar moieties. in Tetrahedron, 58(3), 569-580.
https://doi.org/10.1016/S0040-4020(01)01126-7

Popsavin M, Torovic L, Spaic S, Stankov S, Kapor A, Tomić ZD, Popsavin V. Synthesis and biological evaluation of new pyrazole- and tetrazole-related C-nucleosides with modified sugar moieties. in Tetrahedron. 2002;58(3):569-580.
doi:10.1016/S0040-4020(01)01126-7 .

Popsavin, M, Torovic, L, Spaic, S, Stankov, S, Kapor, Agneš, Tomić, Zoran D., Popsavin, V, "Synthesis and biological evaluation of new pyrazole- and tetrazole-related C-nucleosides with modified sugar moieties" in Tetrahedron, 58, no. 3 (2002):569-580,
https://doi.org/10.1016/S0040-4020(01)01126-7 . .