Đorđević, Neda O.

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orcid::0000-0003-4063-1635
  • Đorđević, Neda O. (6)
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Author's Bibliography

Antidepressants- and antipsychotics-induced hepatotoxicity

Todorović Vukotić, Nevena; Đorđević, Jelena; Pejić, Snežana; Đorđević, Neda O.; Pajović, Snežana B.

(2021)

TY  - JOUR
AU  - Todorović Vukotić, Nevena
AU  - Đorđević, Jelena
AU  - Pejić, Snežana
AU  - Đorđević, Neda O.
AU  - Pajović, Snežana B.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9078
AB  - Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical presentations that can escalate to acute liver failure. The worldwide increase in the use of psychotropic drugs, their long-term use on a daily basis, common comorbidities of psychiatric and metabolic disorders, and polypharmacy in psychiatric patients increase the incidence of psychotropics-induced DILI. During the last 2 decades, hepatotoxicity of various antidepressants (ADs) and antipsychotics (APs) received much attention. Comprehensive review and discussion of accumulated literature data concerning this issue are performed in this study, as hepatotoxic effects of most commonly prescribed ADs and APs are classified, described, and discussed. The review focuses on ADs and APs characterized by the risk of causing liver damage and highlights the ones found to cause life-threatening or severe DILI cases. In parallel, an overview of hepatic oxidative stress, inflammation, and steatosis underlying DILI is provided, followed by extensive review and discussion of the pathophysiology of AD- and AP-induced DILI revealed in case reports, and animal and in vitro studies. The consequences of some ADs and APs ability to affect drug-metabolizing enzymes and therefore provoke drug–drug interactions are also addressed. Continuous collecting of data on drugs, mechanisms, and risk factors for DILI, as well as critical data reviewing, is crucial for easier DILI diagnosis and more efficient risk assessment of AD- and AP-induced DILI. Higher awareness of ADs and APs hepatotoxicity is the prerequisite for their safe use and optimal dosing. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.
T2  - Archives of Toxicology
T1  - Antidepressants- and antipsychotics-induced hepatotoxicity
VL  - 95
IS  - 3
SP  - 767
EP  - 789
DO  - 10.1007/s00204-020-02963-4
ER  - 
@article{
author = "Todorović Vukotić, Nevena and Đorđević, Jelena and Pejić, Snežana and Đorđević, Neda O. and Pajović, Snežana B.",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9078",
abstract = "Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical presentations that can escalate to acute liver failure. The worldwide increase in the use of psychotropic drugs, their long-term use on a daily basis, common comorbidities of psychiatric and metabolic disorders, and polypharmacy in psychiatric patients increase the incidence of psychotropics-induced DILI. During the last 2 decades, hepatotoxicity of various antidepressants (ADs) and antipsychotics (APs) received much attention. Comprehensive review and discussion of accumulated literature data concerning this issue are performed in this study, as hepatotoxic effects of most commonly prescribed ADs and APs are classified, described, and discussed. The review focuses on ADs and APs characterized by the risk of causing liver damage and highlights the ones found to cause life-threatening or severe DILI cases. In parallel, an overview of hepatic oxidative stress, inflammation, and steatosis underlying DILI is provided, followed by extensive review and discussion of the pathophysiology of AD- and AP-induced DILI revealed in case reports, and animal and in vitro studies. The consequences of some ADs and APs ability to affect drug-metabolizing enzymes and therefore provoke drug–drug interactions are also addressed. Continuous collecting of data on drugs, mechanisms, and risk factors for DILI, as well as critical data reviewing, is crucial for easier DILI diagnosis and more efficient risk assessment of AD- and AP-induced DILI. Higher awareness of ADs and APs hepatotoxicity is the prerequisite for their safe use and optimal dosing. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.",
journal = "Archives of Toxicology",
title = "Antidepressants- and antipsychotics-induced hepatotoxicity",
volume = "95",
number = "3",
pages = "767-789",
doi = "10.1007/s00204-020-02963-4"
}
Todorović Vukotić, N., Đorđević, J., Pejić, S., Đorđević, N. O.,& Pajović, S. B. (2021). Antidepressants- and antipsychotics-induced hepatotoxicity.
Archives of Toxicology, 95(3), 767-789.
https://doi.org/10.1007/s00204-020-02963-4
Todorović Vukotić N, Đorđević J, Pejić S, Đorđević NO, Pajović SB. Antidepressants- and antipsychotics-induced hepatotoxicity. Archives of Toxicology. 2021;95(3):767-789
Todorović Vukotić Nevena, Đorđević Jelena, Pejić Snežana, Đorđević Neda O., Pajović Snežana B., "Antidepressants- and antipsychotics-induced hepatotoxicity" Archives of Toxicology, 95, no. 3 (2021):767-789,
https://doi.org/10.1007/s00204-020-02963-4 .
1

An insight into chemical composition and biological activity of Montenegrin Vranac red wine

Đorđević, Neda O.; Novakovic, M.; Pejin, Boris; Živković, Marijana B.; Savic, A.; Mutić, Jelena J.; Tegevic, V.

(2018)

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Novakovic, M.
AU  - Pejin, Boris
AU  - Živković, Marijana B.
AU  - Savic, A.
AU  - Mutić, Jelena J.
AU  - Tegevic, V.
PY  - 2018
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1923
AB  - This study aimed to describe quality and potential health benefits of three Vranac wines obtained from new grape clones (CI, CII and CIII) recently developed and recognised. In this aim, their phenolic profiles, anti-2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical activities along with metal compositions were analyzed. Compared with the commercial one, CII and CIII Vranac wines were found to contain both higher contents of total phenolics, flavonoids and monomeric anthocyanins as well as anti-DPPH radical activities. The most abundant phenolics were gallic acid (8.88-16.36 mg/L), catechin (12.42-24.35 mg/L) and epicatechin (4.30-7.79 mg/L). Finally, the metal content of all the analyzed samples was within the toxicological safety limits. Taken all together, Montenegrin Vranac wines represent a rich source of both phenolics and minerals exhibiting promising antioxidant potential. CII and CIII wines can be considered for commercialising due to their high amounts of gallic acid, catechin and epicatechin, significant K/Na ratios and favourable contents of essential metals making them products with health added values.
T2  - Scientia Horticulturae
T1  - An insight into chemical composition and biological activity of Montenegrin Vranac red wine
VL  - 230
SP  - 142
EP  - 148
DO  - 10.1016/j.scienta.2017.11.033
ER  - 
@article{
author = "Đorđević, Neda O. and Novakovic, M. and Pejin, Boris and Živković, Marijana B. and Savic, A. and Mutić, Jelena J. and Tegevic, V.",
year = "2018",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/1923",
abstract = "This study aimed to describe quality and potential health benefits of three Vranac wines obtained from new grape clones (CI, CII and CIII) recently developed and recognised. In this aim, their phenolic profiles, anti-2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical activities along with metal compositions were analyzed. Compared with the commercial one, CII and CIII Vranac wines were found to contain both higher contents of total phenolics, flavonoids and monomeric anthocyanins as well as anti-DPPH radical activities. The most abundant phenolics were gallic acid (8.88-16.36 mg/L), catechin (12.42-24.35 mg/L) and epicatechin (4.30-7.79 mg/L). Finally, the metal content of all the analyzed samples was within the toxicological safety limits. Taken all together, Montenegrin Vranac wines represent a rich source of both phenolics and minerals exhibiting promising antioxidant potential. CII and CIII wines can be considered for commercialising due to their high amounts of gallic acid, catechin and epicatechin, significant K/Na ratios and favourable contents of essential metals making them products with health added values.",
journal = "Scientia Horticulturae",
title = "An insight into chemical composition and biological activity of Montenegrin Vranac red wine",
volume = "230",
pages = "142-148",
doi = "10.1016/j.scienta.2017.11.033"
}
Đorđević, N. O., Novakovic, M., Pejin, B., Živković, M. B., Savic, A., Mutić, J. J.,& Tegevic, V. (2018). An insight into chemical composition and biological activity of Montenegrin Vranac red wine.
Scientia Horticulturae, 230, 142-148.
https://doi.org/10.1016/j.scienta.2017.11.033
Đorđević NO, Novakovic M, Pejin B, Živković MB, Savic A, Mutić JJ, Tegevic V. An insight into chemical composition and biological activity of Montenegrin Vranac red wine. Scientia Horticulturae. 2018;230:142-148
Đorđević Neda O., Novakovic M., Pejin Boris, Živković Marijana B., Savic A., Mutić Jelena J., Tegevic V., "An insight into chemical composition and biological activity of Montenegrin Vranac red wine" Scientia Horticulturae, 230 (2018):142-148,
https://doi.org/10.1016/j.scienta.2017.11.033 .
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Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine

Đorđević, Neda O.; Todorović, Nevena; Novaković, Irena T.; Pezo, Lato; Pejin, Boris; Maraš, Vesna; Tešević, Vele V.; Pajović, Snežana B.

(2018)

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Todorović, Nevena
AU  - Novaković, Irena T.
AU  - Pezo, Lato
AU  - Pejin, Boris
AU  - Maraš, Vesna
AU  - Tešević, Vele V.
AU  - Pajović, Snežana B.
PY  - 2018
UR  - http://www.mdpi.com/1420-3049/23/8/1971
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/7858
AB  - Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2–stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r2 = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2–stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2–stressed cells and shifted antioxidative defense towards GPx–mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.
T2  - Molecules
T1  - Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine
VL  - 23
IS  - 8
SP  - 1971
DO  - 10.3390/molecules23081971
ER  - 
@article{
author = "Đorđević, Neda O. and Todorović, Nevena and Novaković, Irena T. and Pezo, Lato and Pejin, Boris and Maraš, Vesna and Tešević, Vele V. and Pajović, Snežana B.",
year = "2018",
url = "http://www.mdpi.com/1420-3049/23/8/1971, http://vinar.vin.bg.ac.rs/handle/123456789/7858",
abstract = "Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2–stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r2 = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2–stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2–stressed cells and shifted antioxidative defense towards GPx–mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.",
journal = "Molecules",
title = "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine",
volume = "23",
number = "8",
pages = "1971",
doi = "10.3390/molecules23081971"
}
Đorđević, N. O., Todorović, N., Novaković, I. T., Pezo, L., Pejin, B., Maraš, V., Tešević, V. V.,& Pajović, S. B. (2018). Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine.
Molecules, 23(8), 1971.
https://doi.org/10.3390/molecules23081971
Đorđević NO, Todorović N, Novaković IT, Pezo L, Pejin B, Maraš V, Tešević VV, Pajović SB. Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine. Molecules. 2018;23(8):1971
Đorđević Neda O., Todorović Nevena, Novaković Irena T., Pezo Lato, Pejin Boris, Maraš Vesna, Tešević Vele V., Pajović Snežana B., "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine" Molecules, 23, no. 8 (2018):1971,
https://doi.org/10.3390/molecules23081971 .
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Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro

Đorđević, Neda O.; Pejin, Boris; Novaković, Miroslav M.; Stanković, Dalibor M.; Mutić, Jelena J.; Pajović, Snežana B.; Tešević, Vele V.

(2018)

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav M.
AU  - Stanković, Dalibor M.
AU  - Mutić, Jelena J.
AU  - Pajović, Snežana B.
AU  - Tešević, Vele V.
PY  - 2018
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1863
AB  - The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.
T2  - Natural Product Research
T1  - Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro
VL  - 32
IS  - 3
SP  - 247
EP  - 251
DO  - 10.1080/14786419.2017.1347171
ER  - 
@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav M. and Stanković, Dalibor M. and Mutić, Jelena J. and Pajović, Snežana B. and Tešević, Vele V.",
year = "2018",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/1863",
abstract = "The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.",
journal = "Natural Product Research",
title = "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro",
volume = "32",
number = "3",
pages = "247-251",
doi = "10.1080/14786419.2017.1347171"
}
Đorđević, N. O., Pejin, B., Novaković, M. M., Stanković, D. M., Mutić, J. J., Pajović, S. B.,& Tešević, V. V. (2018). Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro.
Natural Product Research, 32(3), 247-251.
https://doi.org/10.1080/14786419.2017.1347171
Đorđević NO, Pejin B, Novaković MM, Stanković DM, Mutić JJ, Pajović SB, Tešević VV. Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro. Natural Product Research. 2018;32(3):247-251
Đorđević Neda O., Pejin Boris, Novaković Miroslav M., Stanković Dalibor M., Mutić Jelena J., Pajović Snežana B., Tešević Vele V., "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro" Natural Product Research, 32, no. 3 (2018):247-251,
https://doi.org/10.1080/14786419.2017.1347171 .
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Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro

Đorđević, Neda O.; Pejin, Boris; Novaković, Miroslav M.; Stanković, Dalibor M.; Mutić, Jelena J.; Pajović, Snežana B.; Tešević, Vele V.

(2017)

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav M.
AU  - Stanković, Dalibor M.
AU  - Mutić, Jelena J.
AU  - Pajović, Snežana B.
AU  - Tešević, Vele V.
PY  - 2017
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1773
AB  - The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.
T2  - Scientia Horticulturae
T1  - Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro
VL  - 225
SP  - 505
EP  - 511
DO  - 10.1016/j.scienta.2017.07.045
ER  - 
@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav M. and Stanković, Dalibor M. and Mutić, Jelena J. and Pajović, Snežana B. and Tešević, Vele V.",
year = "2017",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/1773",
abstract = "The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.",
journal = "Scientia Horticulturae",
title = "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro",
volume = "225",
pages = "505-511",
doi = "10.1016/j.scienta.2017.07.045"
}
Đorđević, N. O., Pejin, B., Novaković, M. M., Stanković, D. M., Mutić, J. J., Pajović, S. B.,& Tešević, V. V. (2017). Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro.
Scientia Horticulturae, 225, 505-511.
https://doi.org/10.1016/j.scienta.2017.07.045
Đorđević NO, Pejin B, Novaković MM, Stanković DM, Mutić JJ, Pajović SB, Tešević VV. Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro. Scientia Horticulturae. 2017;225:505-511
Đorđević Neda O., Pejin Boris, Novaković Miroslav M., Stanković Dalibor M., Mutić Jelena J., Pajović Snežana B., Tešević Vele V., "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro" Scientia Horticulturae, 225 (2017):505-511,
https://doi.org/10.1016/j.scienta.2017.07.045 .
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Comparative analytical study of the selected wine varieties grown in Montenegro

Đorđević, Neda O.; Novaković, Miroslav M.; Pejin, Boris; Mutić, Jelena J.; Vajs, Vlatka E.; Pajović, Snežana B.; Tešević, Vele V.

(2017)

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav M.
AU  - Pejin, Boris
AU  - Mutić, Jelena J.
AU  - Vajs, Vlatka E.
AU  - Pajović, Snežana B.
AU  - Tešević, Vele V.
PY  - 2017
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1628
AB  - Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .
T2  - Natural Product Research
T1  - Comparative analytical study of the selected wine varieties grown in Montenegro
VL  - 31
IS  - 15
SP  - 1825
EP  - 1830
DO  - 10.1080/14786419.2017.1289209
ER  - 
@article{
author = "Đorđević, Neda O. and Novaković, Miroslav M. and Pejin, Boris and Mutić, Jelena J. and Vajs, Vlatka E. and Pajović, Snežana B. and Tešević, Vele V.",
year = "2017",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/1628",
abstract = "Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .",
journal = "Natural Product Research",
title = "Comparative analytical study of the selected wine varieties grown in Montenegro",
volume = "31",
number = "15",
pages = "1825-1830",
doi = "10.1080/14786419.2017.1289209"
}
Đorđević, N. O., Novaković, M. M., Pejin, B., Mutić, J. J., Vajs, V. E., Pajović, S. B.,& Tešević, V. V. (2017). Comparative analytical study of the selected wine varieties grown in Montenegro.
Natural Product Research, 31(15), 1825-1830.
https://doi.org/10.1080/14786419.2017.1289209
Đorđević NO, Novaković MM, Pejin B, Mutić JJ, Vajs VE, Pajović SB, Tešević VV. Comparative analytical study of the selected wine varieties grown in Montenegro. Natural Product Research. 2017;31(15):1825-1830
Đorđević Neda O., Novaković Miroslav M., Pejin Boris, Mutić Jelena J., Vajs Vlatka E., Pajović Snežana B., Tešević Vele V., "Comparative analytical study of the selected wine varieties grown in Montenegro" Natural Product Research, 31, no. 15 (2017):1825-1830,
https://doi.org/10.1080/14786419.2017.1289209 .
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