TY  - JOUR
AU  - Vučina, Jurij L.
AU  - Nikolić, Nadežda S.
AU  - Petrović, Đokica
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3687
AB  - Several types of generators have been developed for the production of (99m)Tc. Due to its excelent performances, the chromatographic type, based on the fission-produced (99)Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-(99m)Tc. However, due to the known disadvantages of the production of (n, f)(99)Mo, attempts are made to avoid uranium fission. The technologies based on (n, gamma)(99)Mo (sublimation, extraction, gel) are, with the exception of the gel generator, of limited importance. Certain nuclear reactions in cyclotrons can produce (99)Mo (or directly (99m)Tc) but the obtained results are still not satisfying. Technetium-99m is used in the form of radiopharmaceuticals which are prepared by addition of (99m)Tc-eluate to the inactive components comprised in the cold kits. The chromatographic (n, f)(99)Mo/(99m)Tc generator and several (99m)Tc-radiopharmaceuticals have been developed and are regularly produced in the Vinca Institute of Nuclear Sciences (Laboratory for Radioisotopes).
T2  - Nuclear technology and radiation protection
T1  - Technetium-99m in Production and Use
VL  - 24
IS  - 1
SP  - 68
EP  - 73
DO  - 10.2298/NTRP0901068V
ER  - 

@article{
author = "Vučina, Jurij L. and Nikolić, Nadežda S. and Petrović, Đokica",
year = "2009",
abstract = "Several types of generators have been developed for the production of (99m)Tc. Due to its excelent performances, the chromatographic type, based on the fission-produced (99)Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-(99m)Tc. However, due to the known disadvantages of the production of (n, f)(99)Mo, attempts are made to avoid uranium fission. The technologies based on (n, gamma)(99)Mo (sublimation, extraction, gel) are, with the exception of the gel generator, of limited importance. Certain nuclear reactions in cyclotrons can produce (99)Mo (or directly (99m)Tc) but the obtained results are still not satisfying. Technetium-99m is used in the form of radiopharmaceuticals which are prepared by addition of (99m)Tc-eluate to the inactive components comprised in the cold kits. The chromatographic (n, f)(99)Mo/(99m)Tc generator and several (99m)Tc-radiopharmaceuticals have been developed and are regularly produced in the Vinca Institute of Nuclear Sciences (Laboratory for Radioisotopes).",
journal = "Nuclear technology and radiation protection",
title = "Technetium-99m in Production and Use",
volume = "24",
number = "1",
pages = "68-73",
doi = "10.2298/NTRP0901068V"
}

Vučina, J. L., Nikolić, N. S.,& Petrović, Đ.. (2009). Technetium-99m in Production and Use. in Nuclear technology and radiation protection, 24(1), 68-73.
https://doi.org/10.2298/NTRP0901068V

Vučina JL, Nikolić NS, Petrović Đ. Technetium-99m in Production and Use. in Nuclear technology and radiation protection. 2009;24(1):68-73.
doi:10.2298/NTRP0901068V .

Vučina, Jurij L., Nikolić, Nadežda S., Petrović, Đokica, "Technetium-99m in Production and Use" in Nuclear technology and radiation protection, 24, no. 1 (2009):68-73,
https://doi.org/10.2298/NTRP0901068V . .

TY  - JOUR
AU  - Lukić, Dragoljub M.
AU  - Vučina, Jurij L.
AU  - Milonjić, Slobodan K.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3402
AB  - The conditions for the desorption of rhenium from the anion exchange resin Dowex 1-x8 by HNO3, FlCl, H2SO4 and NaOH were determined. The solution (5.0 x 10(-3) mol dm(-3) Re in 0.15 mot dm(-3) NaCl) was passed through a column containing 0.10 g of the resin. The total sorbed amount of rhenium was 0.20 g/g of the resin. It was then eluted by the corresponding eluent in the concentration range up to about 3.0 mol dm(-3). The highest elution efficiency and the most favourable elution profile were found with 3.0 mol dm(-3) HNO3. Over 77 % of the sorbed rhenium was found in the first 5 ml of the eluate. Practically all the rhenium was recovered with 20 ml of the acid. Under the given experimental conditions, HCl and H2SO4 were less favourable while NaOH was not applicable, due to very low efficiency of rhenium elution.
T2  - Journal of the Serbian Chemical Society
T1  - Concentration of rhenium from dilute sodium chloride solutions
VL  - 73
IS  - 3
SP  - 333
EP  - 339
DO  - 10.2298/JSC0803333L
ER  - 

@article{
author = "Lukić, Dragoljub M. and Vučina, Jurij L. and Milonjić, Slobodan K.",
year = "2008",
abstract = "The conditions for the desorption of rhenium from the anion exchange resin Dowex 1-x8 by HNO3, FlCl, H2SO4 and NaOH were determined. The solution (5.0 x 10(-3) mol dm(-3) Re in 0.15 mot dm(-3) NaCl) was passed through a column containing 0.10 g of the resin. The total sorbed amount of rhenium was 0.20 g/g of the resin. It was then eluted by the corresponding eluent in the concentration range up to about 3.0 mol dm(-3). The highest elution efficiency and the most favourable elution profile were found with 3.0 mol dm(-3) HNO3. Over 77 % of the sorbed rhenium was found in the first 5 ml of the eluate. Practically all the rhenium was recovered with 20 ml of the acid. Under the given experimental conditions, HCl and H2SO4 were less favourable while NaOH was not applicable, due to very low efficiency of rhenium elution.",
journal = "Journal of the Serbian Chemical Society",
title = "Concentration of rhenium from dilute sodium chloride solutions",
volume = "73",
number = "3",
pages = "333-339",
doi = "10.2298/JSC0803333L"
}

Lukić, D. M., Vučina, J. L.,& Milonjić, S. K.. (2008). Concentration of rhenium from dilute sodium chloride solutions. in Journal of the Serbian Chemical Society, 73(3), 333-339.
https://doi.org/10.2298/JSC0803333L

Lukić DM, Vučina JL, Milonjić SK. Concentration of rhenium from dilute sodium chloride solutions. in Journal of the Serbian Chemical Society. 2008;73(3):333-339.
doi:10.2298/JSC0803333L .

Lukić, Dragoljub M., Vučina, Jurij L., Milonjić, Slobodan K., "Concentration of rhenium from dilute sodium chloride solutions" in Journal of the Serbian Chemical Society, 73, no. 3 (2008):333-339,
https://doi.org/10.2298/JSC0803333L . .

TY  - JOUR
AU  - Lukić, Dragoljub M.
AU  - Vučina, Jurij L.
AU  - Milonjić, Slobodan K.
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3215
AB  - The separation of tungstate and perrhenate anions on alumina from aqueous solutions of sodium chloride was investigated in dynamic conditions. The breakthrough curves for W and Re as the function of the ratio of their concentrations in the solution, were determined. The flow rate (3 ml/min), pH 2 and NaCl concentration (0.15 mol/l) were kept constant throughout the experiments. The breakthrough capacities Q(0.05), the capacities at C/C-0 = 0.5, the total column sorption capacities Q(0.9) and the utilization degrees or column efficiencies E, were determined. According to the obtained data the separation factors alpha(W/Re) = Q(w)/Q(Re) were calculated.
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - Separation of tungsten and rhenium on alumina in dynamic conditions
VL  - 273
IS  - 2
SP  - 357
EP  - 362
DO  - 10.1007/s10967-007-6876-x
ER  - 

@article{
author = "Lukić, Dragoljub M. and Vučina, Jurij L. and Milonjić, Slobodan K.",
year = "2007",
abstract = "The separation of tungstate and perrhenate anions on alumina from aqueous solutions of sodium chloride was investigated in dynamic conditions. The breakthrough curves for W and Re as the function of the ratio of their concentrations in the solution, were determined. The flow rate (3 ml/min), pH 2 and NaCl concentration (0.15 mol/l) were kept constant throughout the experiments. The breakthrough capacities Q(0.05), the capacities at C/C-0 = 0.5, the total column sorption capacities Q(0.9) and the utilization degrees or column efficiencies E, were determined. According to the obtained data the separation factors alpha(W/Re) = Q(w)/Q(Re) were calculated.",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "Separation of tungsten and rhenium on alumina in dynamic conditions",
volume = "273",
number = "2",
pages = "357-362",
doi = "10.1007/s10967-007-6876-x"
}

Lukić, D. M., Vučina, J. L.,& Milonjić, S. K.. (2007). Separation of tungsten and rhenium on alumina in dynamic conditions. in Journal of Radioanalytical and Nuclear Chemistry, 273(2), 357-362.
https://doi.org/10.1007/s10967-007-6876-x

Lukić DM, Vučina JL, Milonjić SK. Separation of tungsten and rhenium on alumina in dynamic conditions. in Journal of Radioanalytical and Nuclear Chemistry. 2007;273(2):357-362.
doi:10.1007/s10967-007-6876-x .

Lukić, Dragoljub M., Vučina, Jurij L., Milonjić, Slobodan K., "Separation of tungsten and rhenium on alumina in dynamic conditions" in Journal of Radioanalytical and Nuclear Chemistry, 273, no. 2 (2007):357-362,
https://doi.org/10.1007/s10967-007-6876-x . .

TY  - JOUR
AU  - Lukić, Dragoljub M.
AU  - Vučina, Jurij L.
AU  - Milonjić, Slobodan K.
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3221
AB  - The sorption of perrhenate anion on alumina from aqueous solutions of sodium chloride was investigated under dynamic conditions. The initial concentrations of rhenium were in the range of 2.7 x 10(-2)-2.7 mmol/dM(3). The breakthrough curves as the function of Re and NaCl concentrations (0. 12-0.20 mol/dm(3)), pH 2-6 and flow rate 3-10 ml/min were determined. According to the experimental results, it was concluded that the breakthrough capacities, the capacities at c/c(0) = 0.5, the total column capacities and the utilization degrees (column efficiency) increase with increasing Re and NaCl concentrations and decreasing pH. The optimal flow rate was found to be 3 ml/min. At pH 2 and c(0) = 2.7 mmol Re/dm(3), the total capacity was found to be Q(0.9) (max) = 2.1 x 10(-2) mmol Re/g Al2O3. The data for perrhenate anions fit with a Henry-type isotherm. It was found that, under the above mentioned conditions, the value of the Henry constant K-H was 7.8 x 10(-3) dm(3)/g and the Gibbs energy change, Delta G was -0.5 kJ/mol.
T2  - Journal of the Serbian Chemical Society
T1  - Sorption of rhenium on alumina under dynamic conditions
VL  - 72
IS  - 6
SP  - 555
EP  - 562
DO  - 10.2298/JSC0706555L
ER  - 

@article{
author = "Lukić, Dragoljub M. and Vučina, Jurij L. and Milonjić, Slobodan K.",
year = "2007",
abstract = "The sorption of perrhenate anion on alumina from aqueous solutions of sodium chloride was investigated under dynamic conditions. The initial concentrations of rhenium were in the range of 2.7 x 10(-2)-2.7 mmol/dM(3). The breakthrough curves as the function of Re and NaCl concentrations (0. 12-0.20 mol/dm(3)), pH 2-6 and flow rate 3-10 ml/min were determined. According to the experimental results, it was concluded that the breakthrough capacities, the capacities at c/c(0) = 0.5, the total column capacities and the utilization degrees (column efficiency) increase with increasing Re and NaCl concentrations and decreasing pH. The optimal flow rate was found to be 3 ml/min. At pH 2 and c(0) = 2.7 mmol Re/dm(3), the total capacity was found to be Q(0.9) (max) = 2.1 x 10(-2) mmol Re/g Al2O3. The data for perrhenate anions fit with a Henry-type isotherm. It was found that, under the above mentioned conditions, the value of the Henry constant K-H was 7.8 x 10(-3) dm(3)/g and the Gibbs energy change, Delta G was -0.5 kJ/mol.",
journal = "Journal of the Serbian Chemical Society",
title = "Sorption of rhenium on alumina under dynamic conditions",
volume = "72",
number = "6",
pages = "555-562",
doi = "10.2298/JSC0706555L"
}

Lukić, D. M., Vučina, J. L.,& Milonjić, S. K.. (2007). Sorption of rhenium on alumina under dynamic conditions. in Journal of the Serbian Chemical Society, 72(6), 555-562.
https://doi.org/10.2298/JSC0706555L

Lukić DM, Vučina JL, Milonjić SK. Sorption of rhenium on alumina under dynamic conditions. in Journal of the Serbian Chemical Society. 2007;72(6):555-562.
doi:10.2298/JSC0706555L .

Lukić, Dragoljub M., Vučina, Jurij L., Milonjić, Slobodan K., "Sorption of rhenium on alumina under dynamic conditions" in Journal of the Serbian Chemical Society, 72, no. 6 (2007):555-562,
https://doi.org/10.2298/JSC0706555L . .

TY  - CONF
AU  - Vučina, Jurij L.
AU  - Lukić, Dragoljub
AU  - Milonjić, Slobodan K.
AU  - Stoiljković, Milovan
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9443
AB  - The conditions of the desorption of rhenium from the anion exchange resin Dowex 1×8 by nitric acid were determined. The solution (5×10-3 mol/dm3  Re in 0.15 mol/dm3 NaCl) was passed through the column containing 0.1 g of the resin. The total sorbed amount of rhenium was 200 mg/g of the resin. It was then eluted by nitric acid in the concentration range of 0.16-7.2 mol/dm3 . The most favourable elution profile was found with 3.0 mol/dm3  HNO3. Over 77% of the total rhenium was desorbed with 5 ml of this eluence. Over 95% of the sorbed rhenium was recovered by using 20 ml of nitric acid in the concentration range of 0.9-7.2 mol/dm3 .
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
T1  - Preparation of concentrated rhenium solutions
SP  - 457
EP  - 459
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9443
ER  - 

@conference{
author = "Vučina, Jurij L. and Lukić, Dragoljub and Milonjić, Slobodan K. and Stoiljković, Milovan",
year = "2006",
abstract = "The conditions of the desorption of rhenium from the anion exchange resin Dowex 1×8 by nitric acid were determined. The solution (5×10-3 mol/dm3  Re in 0.15 mol/dm3 NaCl) was passed through the column containing 0.1 g of the resin. The total sorbed amount of rhenium was 200 mg/g of the resin. It was then eluted by nitric acid in the concentration range of 0.16-7.2 mol/dm3 . The most favourable elution profile was found with 3.0 mol/dm3  HNO3. Over 77% of the total rhenium was desorbed with 5 ml of this eluence. Over 95% of the sorbed rhenium was recovered by using 20 ml of nitric acid in the concentration range of 0.9-7.2 mol/dm3 .",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry",
title = "Preparation of concentrated rhenium solutions",
pages = "457-459",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9443"
}

Vučina, J. L., Lukić, D., Milonjić, S. K.,& Stoiljković, M.. (2006). Preparation of concentrated rhenium solutions. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 457-459.
https://hdl.handle.net/21.15107/rcub_vinar_9443

Vučina JL, Lukić D, Milonjić SK, Stoiljković M. Preparation of concentrated rhenium solutions. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry. 2006;:457-459.
https://hdl.handle.net/21.15107/rcub_vinar_9443 .

Vučina, Jurij L., Lukić, Dragoljub, Milonjić, Slobodan K., Stoiljković, Milovan, "Preparation of concentrated rhenium solutions" in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry (2006):457-459,
https://hdl.handle.net/21.15107/rcub_vinar_9443 .

TY  - JOUR
AU  - Vučina, Jurij L.
AU  - Lukić, Dragoljub M.
AU  - Milonjić, Slobodan K.
AU  - Stoiljković, Milovan
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2970
AB  - The sorption of tungstate anions on alumina from aqueous solutions of sodium chloride was investigated in dynamic conditions. The breakthrough curves as the function of W and NaCl concentrations, pH and the flow rates were determined. The breakthrough capacities, the capacities at C/C-0 = 0.5, the total column sorption capacities and the utilization degrees or column efficiencies, were determined. The obtained tungstate anion sorption data fit with a Langmuir-type isotherm. The values of the breakthrough capacity, Q(0.9)(max), the Langmuir equilibrium constant or affinity parameter, K-L, and the free energy change, Delta G, of tungsten sorption were also determined.
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - Sorption of tungsten on alumina in dynamic conditions
VL  - 267
IS  - 1
SP  - 67
EP  - 72
DO  - 10.1007/s10967-006-0010-3
ER  - 

@article{
author = "Vučina, Jurij L. and Lukić, Dragoljub M. and Milonjić, Slobodan K. and Stoiljković, Milovan",
year = "2005",
abstract = "The sorption of tungstate anions on alumina from aqueous solutions of sodium chloride was investigated in dynamic conditions. The breakthrough curves as the function of W and NaCl concentrations, pH and the flow rates were determined. The breakthrough capacities, the capacities at C/C-0 = 0.5, the total column sorption capacities and the utilization degrees or column efficiencies, were determined. The obtained tungstate anion sorption data fit with a Langmuir-type isotherm. The values of the breakthrough capacity, Q(0.9)(max), the Langmuir equilibrium constant or affinity parameter, K-L, and the free energy change, Delta G, of tungsten sorption were also determined.",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "Sorption of tungsten on alumina in dynamic conditions",
volume = "267",
number = "1",
pages = "67-72",
doi = "10.1007/s10967-006-0010-3"
}

Vučina, J. L., Lukić, D. M., Milonjić, S. K.,& Stoiljković, M.. (2005). Sorption of tungsten on alumina in dynamic conditions. in Journal of Radioanalytical and Nuclear Chemistry, 267(1), 67-72.
https://doi.org/10.1007/s10967-006-0010-3

Vučina JL, Lukić DM, Milonjić SK, Stoiljković M. Sorption of tungsten on alumina in dynamic conditions. in Journal of Radioanalytical and Nuclear Chemistry. 2005;267(1):67-72.
doi:10.1007/s10967-006-0010-3 .

Vučina, Jurij L., Lukić, Dragoljub M., Milonjić, Slobodan K., Stoiljković, Milovan, "Sorption of tungsten on alumina in dynamic conditions" in Journal of Radioanalytical and Nuclear Chemistry, 267, no. 1 (2005):67-72,
https://doi.org/10.1007/s10967-006-0010-3 . .

TY  - CONF
AU  - Vučina, Jurij L.
AU  - Lukić, Dragoljub
AU  - Stoiljković, Milovan
AU  - Milošević, Miodrag
AU  - Orlić, Milan P.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9595
AB  - Examined were the conditions for an effective separation of tungsten(VI) and rhenium(VII) on alumina if the solution of 0.20 mol dm-3 NaCl, pH=2-6, is used as the aqueous phase. Under the given experimental conditions alumina was found to be much better adsorbent for tungsten than for rhenium. The breakthrough and saturation capacities of alumina at pH = 2 are 24 and 78 mg W/g Al2O3, respectively. With the increase of pH these values decrease. So, at pH = 6 they are only 4 and 13 mg W/g Al2O3, respectively. The elution volume for rhenium for the given column dimensions and the quantity of the adsorbent, is about 16 ml. These results were confirmed by the experiments of the radiochemical separations. Tungsten-187 remains firmly bound to alumina. The radionuclidic purity of the eluted 186,188 Re at pH = 2 is very high.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
T1  - Separation of rhenium (VIII) from tungsten (VI)
VL  - 2
SP  - 748
EP  - 750
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9595
ER  - 

@conference{
author = "Vučina, Jurij L. and Lukić, Dragoljub and Stoiljković, Milovan and Milošević, Miodrag and Orlić, Milan P.",
year = "2004",
abstract = "Examined were the conditions for an effective separation of tungsten(VI) and rhenium(VII) on alumina if the solution of 0.20 mol dm-3 NaCl, pH=2-6, is used as the aqueous phase. Under the given experimental conditions alumina was found to be much better adsorbent for tungsten than for rhenium. The breakthrough and saturation capacities of alumina at pH = 2 are 24 and 78 mg W/g Al2O3, respectively. With the increase of pH these values decrease. So, at pH = 6 they are only 4 and 13 mg W/g Al2O3, respectively. The elution volume for rhenium for the given column dimensions and the quantity of the adsorbent, is about 16 ml. These results were confirmed by the experiments of the radiochemical separations. Tungsten-187 remains firmly bound to alumina. The radionuclidic purity of the eluted 186,188 Re at pH = 2 is very high.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry",
title = "Separation of rhenium (VIII) from tungsten (VI)",
volume = "2",
pages = "748-750",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9595"
}

Vučina, J. L., Lukić, D., Stoiljković, M., Milošević, M.,& Orlić, M. P.. (2004). Separation of rhenium (VIII) from tungsten (VI). in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 2, 748-750.
https://hdl.handle.net/21.15107/rcub_vinar_9595

Vučina JL, Lukić D, Stoiljković M, Milošević M, Orlić MP. Separation of rhenium (VIII) from tungsten (VI). in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;2:748-750.
https://hdl.handle.net/21.15107/rcub_vinar_9595 .

Vučina, Jurij L., Lukić, Dragoljub, Stoiljković, Milovan, Milošević, Miodrag, Orlić, Milan P., "Separation of rhenium (VIII) from tungsten (VI)" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 2 (2004):748-750,
https://hdl.handle.net/21.15107/rcub_vinar_9595 .

TY  - CONF
AU  - Nikolić, Nadežda S.
AU  - Veselinović, Dragan S.
AU  - Vučina, Jurij L.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9599
AB  - The influence of the magnetic field with the magnetic induction up to 1,35T on the reduction of 4,8-diaza-3,6,6,9-tetramethylundecane-3,8-diene-2,10-dione dioxime (DI) in anhydrous protic solvents (anhydrous ethanol and 2-propanol) was defined. As the reductants NaBH4 and KBH4 were used
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
T1  - Influence of magnetic field on the reduction of 4,8-diaza-3,6,6,9-tetramethyl undecane-3,8-diene2,10-dione dioxime
VL  - 2
SP  - 778
EP  - 780
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9599
ER  - 

@conference{
author = "Nikolić, Nadežda S. and Veselinović, Dragan S. and Vučina, Jurij L.",
year = "2004",
abstract = "The influence of the magnetic field with the magnetic induction up to 1,35T on the reduction of 4,8-diaza-3,6,6,9-tetramethylundecane-3,8-diene-2,10-dione dioxime (DI) in anhydrous protic solvents (anhydrous ethanol and 2-propanol) was defined. As the reductants NaBH4 and KBH4 were used",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry",
title = "Influence of magnetic field on the reduction of 4,8-diaza-3,6,6,9-tetramethyl undecane-3,8-diene2,10-dione dioxime",
volume = "2",
pages = "778-780",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9599"
}

Nikolić, N. S., Veselinović, D. S.,& Vučina, J. L.. (2004). Influence of magnetic field on the reduction of 4,8-diaza-3,6,6,9-tetramethyl undecane-3,8-diene2,10-dione dioxime. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 2, 778-780.
https://hdl.handle.net/21.15107/rcub_vinar_9599

Nikolić NS, Veselinović DS, Vučina JL. Influence of magnetic field on the reduction of 4,8-diaza-3,6,6,9-tetramethyl undecane-3,8-diene2,10-dione dioxime. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;2:778-780.
https://hdl.handle.net/21.15107/rcub_vinar_9599 .

Nikolić, Nadežda S., Veselinović, Dragan S., Vučina, Jurij L., "Influence of magnetic field on the reduction of 4,8-diaza-3,6,6,9-tetramethyl undecane-3,8-diene2,10-dione dioxime" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 2 (2004):778-780,
https://hdl.handle.net/21.15107/rcub_vinar_9599 .

TY  - JOUR
AU  - Vučina, Jurij L.
AU  - Lukić, Dragoljub M.
AU  - Stoiljković, Milovan
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2814
AB  - The conditions for the efficient separation of tungsten(VI) and rhenium (VII) on alumina were established. The distribution coefficients K-d for tunstate and perrhenate anions, as well as the separation factors alpha (alpha = K-dWO4(2-)/K-d ReO4-) were determined using hydrochloric or nitric acid as the aqueous media. A solution of sodium chloride in the pH range 2-6 was also examined. Under all the tested experimental conditions. alumina is a much better adsorbent for tungsten than for rhenium. The obtained results indicated that the best separation of these two elements is achieved when 0.01-0.1 mol dm(-3) HCl or 1.0 mol dm(-3) HNO3 are used as the aqueous media. If NaCl is used as the aqueous phase, the best separation is achieved with 0.20 mol dm(-3) NaCl. pH 4-6. Under these experimental conditions. the breakthrough and saturation capacities of alumina for tungsten at pH 4 are 17 and 26 mg W/g Al2O3. respectively. With increasing pH, these values decrease. Thus, at pH 6 they are only 4 and 13 mg W/g Al2O3, respectively.
T2  - Journal of the Serbian Chemical Society
T1  - Separation of tungsten and rhenium on alumina
VL  - 69
IS  - 8-9
SP  - 683
EP  - 688
DO  - 10.2298/JSC0409683V
ER  - 

@article{
author = "Vučina, Jurij L. and Lukić, Dragoljub M. and Stoiljković, Milovan",
year = "2004",
abstract = "The conditions for the efficient separation of tungsten(VI) and rhenium (VII) on alumina were established. The distribution coefficients K-d for tunstate and perrhenate anions, as well as the separation factors alpha (alpha = K-dWO4(2-)/K-d ReO4-) were determined using hydrochloric or nitric acid as the aqueous media. A solution of sodium chloride in the pH range 2-6 was also examined. Under all the tested experimental conditions. alumina is a much better adsorbent for tungsten than for rhenium. The obtained results indicated that the best separation of these two elements is achieved when 0.01-0.1 mol dm(-3) HCl or 1.0 mol dm(-3) HNO3 are used as the aqueous media. If NaCl is used as the aqueous phase, the best separation is achieved with 0.20 mol dm(-3) NaCl. pH 4-6. Under these experimental conditions. the breakthrough and saturation capacities of alumina for tungsten at pH 4 are 17 and 26 mg W/g Al2O3. respectively. With increasing pH, these values decrease. Thus, at pH 6 they are only 4 and 13 mg W/g Al2O3, respectively.",
journal = "Journal of the Serbian Chemical Society",
title = "Separation of tungsten and rhenium on alumina",
volume = "69",
number = "8-9",
pages = "683-688",
doi = "10.2298/JSC0409683V"
}

Vučina, J. L., Lukić, D. M.,& Stoiljković, M.. (2004). Separation of tungsten and rhenium on alumina. in Journal of the Serbian Chemical Society, 69(8-9), 683-688.
https://doi.org/10.2298/JSC0409683V

Vučina JL, Lukić DM, Stoiljković M. Separation of tungsten and rhenium on alumina. in Journal of the Serbian Chemical Society. 2004;69(8-9):683-688.
doi:10.2298/JSC0409683V .

Vučina, Jurij L., Lukić, Dragoljub M., Stoiljković, Milovan, "Separation of tungsten and rhenium on alumina" in Journal of the Serbian Chemical Society, 69, no. 8-9 (2004):683-688,
https://doi.org/10.2298/JSC0409683V . .

TY  - JOUR
AU  - Nikolić, Nadežda S.
AU  - Veselinović, Dragan S.
AU  - Vučina, Jurij L.
AU  - Lingeman, H
AU  - Karljiković-Rajić, Katarina
PY  - 2003
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2661
AB  - The diastereo-enantio separation of isomeric mixtures of exametazime (HM-PAO) by liquid chromatography is described using an achiral sorbent (RP-18). A chiral eluent with the initial complex of Cu(II) and the optically active selector N,N-dimethyl-l-phenylalanine (l-DM-PhA), based on the ligand-exchange principle, has been applied. The separation is based on the presence of the immobilized binary complex Cu(l-DM-PhA)(2) and formation of mixed ternary complex. The optimal mole ratio of Cu(II):l-DM-PhA is 1:4, the pH should be between 4.1 and 4.2 and up to 0.8 mM of triethylamine is added for column presaturation with the initial complex. The elution order has been defined using isolated l-HM-PAO via l-HM-PAO L(+)tartrate and tneso-HM-PAO obtained by repeated recrystallization from the isomeric mixture of HM-PAO. Complete resolution between all isomers (R-S from 2.14 to 3.91) and partial resolution for meso(EE)/l-HM-PAO (R-S = 0.83) has been obtained. This means that the proposed chiral ligand-exchange chromatography (CLEC) can be used for determination of the isomeric purity of HM-PAO. This as an alternative method for resolution measurements with chiral columns. (C) 2003 Elsevier B.V. All rights reserved.
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime
VL  - 32
IS  - 6
SP  - 1159
EP  - 1166
DO  - 10.1016/S0731-7085(03)00230-9
ER  - 

@article{
author = "Nikolić, Nadežda S. and Veselinović, Dragan S. and Vučina, Jurij L. and Lingeman, H and Karljiković-Rajić, Katarina",
year = "2003",
abstract = "The diastereo-enantio separation of isomeric mixtures of exametazime (HM-PAO) by liquid chromatography is described using an achiral sorbent (RP-18). A chiral eluent with the initial complex of Cu(II) and the optically active selector N,N-dimethyl-l-phenylalanine (l-DM-PhA), based on the ligand-exchange principle, has been applied. The separation is based on the presence of the immobilized binary complex Cu(l-DM-PhA)(2) and formation of mixed ternary complex. The optimal mole ratio of Cu(II):l-DM-PhA is 1:4, the pH should be between 4.1 and 4.2 and up to 0.8 mM of triethylamine is added for column presaturation with the initial complex. The elution order has been defined using isolated l-HM-PAO via l-HM-PAO L(+)tartrate and tneso-HM-PAO obtained by repeated recrystallization from the isomeric mixture of HM-PAO. Complete resolution between all isomers (R-S from 2.14 to 3.91) and partial resolution for meso(EE)/l-HM-PAO (R-S = 0.83) has been obtained. This means that the proposed chiral ligand-exchange chromatography (CLEC) can be used for determination of the isomeric purity of HM-PAO. This as an alternative method for resolution measurements with chiral columns. (C) 2003 Elsevier B.V. All rights reserved.",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime",
volume = "32",
number = "6",
pages = "1159-1166",
doi = "10.1016/S0731-7085(03)00230-9"
}

Nikolić, N. S., Veselinović, D. S., Vučina, J. L., Lingeman, H.,& Karljiković-Rajić, K.. (2003). Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime. in Journal of Pharmaceutical and Biomedical Analysis, 32(6), 1159-1166.
https://doi.org/10.1016/S0731-7085(03)00230-9

Nikolić NS, Veselinović DS, Vučina JL, Lingeman H, Karljiković-Rajić K. Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime. in Journal of Pharmaceutical and Biomedical Analysis. 2003;32(6):1159-1166.
doi:10.1016/S0731-7085(03)00230-9 .

Nikolić, Nadežda S., Veselinović, Dragan S., Vučina, Jurij L., Lingeman, H, Karljiković-Rajić, Katarina, "Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime" in Journal of Pharmaceutical and Biomedical Analysis, 32, no. 6 (2003):1159-1166,
https://doi.org/10.1016/S0731-7085(03)00230-9 . .

TY  - JOUR
AU  - Vučina, Jurij L.
AU  - Lukić, Dragoljub M.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10145
AB  - The paper deals with production and application of open radioactive sources in modern diagnostic and therapeutic nuclear medicine. In principle, besides adequate physical, chemical and biological properties a reliable route for the routine production of both radionuclide and radiopharmaceutical should be on disposal. The favorite route are radionuclidic generators as they enable simple production of shorter-lived radionuclides at relatively low costs. The main radionuclide in diagnosis is technetium-99m. Its advantages are favorable nuclear properties, availability of large activities of high quality 99m Tc at reasonable prices by using (n,f)99Mo/ 99m Tc generators and versatile chemistry. It is used in the investigation of practically all organs and tissues in the human body. Among the beta- emitters the radionuclides of rhenium have been recently proposed as suitable candidates for therapeutic applications. The most important is 188Re which is obtained from 188W/ 188Re generator. Some of the important radiopharmaceuticals labeled with rhenium radionuclides used for certain specific indications are also shown. The activities performed in the Laboratory for Radioisotopes (Vinča Institute of Nuclear Sciences) are also enclosed.
AB  - Prikazani su neki od najvažnijih aspekata proizvodnje i primene otvorenih izvora radioaktivnog zračenja u dijagnostičkoj i terapijskoj nuklearnoj medicini. Pored fizičkih, bitne su i hemijske i biohemijske osobine datog radionuklida odnosno radiofarmaceutika. Uslov za redovnu primenu su i dostupnost, kvalitet i cena. Radionuklidni generatori predstavljaju vrlo pogodan izvor dobijanja radionuklida kraćih vremena poluraspada. Najvažniji dijagnostički radionuklid je 99m Tc. Odlične fizičke osobine, visok kvalitet i laka dostupnost po prihvatljivim cenama korišćenjem molibden-99/tehnecijum- 99m generatora i razvijena hemija doveli su do toga da ovaj radionuklid postane praktično nezamenjiv u ispitivanju skoro svih organa i tkiva u ljudskom organizmu. Dati su savremeni trendovi u razvoju proizvodnje radionuklida i radiofarmaceutika za primenu u terapijske svrhe. Prikazani su načini dobijanja radionuklida renijuma (186Re i 188Re) sa posebnim naglaskom na 188W/ 188Re generatoru. Dati su hemijski oblici i indikacije za primenu nekih radioaktivnih lekova obeleženih ovim radionuklidima. Prikazana su istraživanja sprovedena u Laboratoriji za radioizotope (Institut za nuklearne nauke «Vinča»).
T2  - Facta Universitatis, Series: Physics, Chemistry and Technology
T1  - Radionuclidic generators for the production of technetium-99m and rhenium-188
T1  - Radionuklidni generatori za dobijanje tehnecijuma-99m i renijuma-188
VL  - 2
IS  - 4
SP  - 235
EP  - 243
DO  - 10.2298/FUPCT0204235V
ER  - 

@article{
author = "Vučina, Jurij L. and Lukić, Dragoljub M.",
year = "2002",
abstract = "The paper deals with production and application of open radioactive sources in modern diagnostic and therapeutic nuclear medicine. In principle, besides adequate physical, chemical and biological properties a reliable route for the routine production of both radionuclide and radiopharmaceutical should be on disposal. The favorite route are radionuclidic generators as they enable simple production of shorter-lived radionuclides at relatively low costs. The main radionuclide in diagnosis is technetium-99m. Its advantages are favorable nuclear properties, availability of large activities of high quality 99m Tc at reasonable prices by using (n,f)99Mo/ 99m Tc generators and versatile chemistry. It is used in the investigation of practically all organs and tissues in the human body. Among the beta- emitters the radionuclides of rhenium have been recently proposed as suitable candidates for therapeutic applications. The most important is 188Re which is obtained from 188W/ 188Re generator. Some of the important radiopharmaceuticals labeled with rhenium radionuclides used for certain specific indications are also shown. The activities performed in the Laboratory for Radioisotopes (Vinča Institute of Nuclear Sciences) are also enclosed., Prikazani su neki od najvažnijih aspekata proizvodnje i primene otvorenih izvora radioaktivnog zračenja u dijagnostičkoj i terapijskoj nuklearnoj medicini. Pored fizičkih, bitne su i hemijske i biohemijske osobine datog radionuklida odnosno radiofarmaceutika. Uslov za redovnu primenu su i dostupnost, kvalitet i cena. Radionuklidni generatori predstavljaju vrlo pogodan izvor dobijanja radionuklida kraćih vremena poluraspada. Najvažniji dijagnostički radionuklid je 99m Tc. Odlične fizičke osobine, visok kvalitet i laka dostupnost po prihvatljivim cenama korišćenjem molibden-99/tehnecijum- 99m generatora i razvijena hemija doveli su do toga da ovaj radionuklid postane praktično nezamenjiv u ispitivanju skoro svih organa i tkiva u ljudskom organizmu. Dati su savremeni trendovi u razvoju proizvodnje radionuklida i radiofarmaceutika za primenu u terapijske svrhe. Prikazani su načini dobijanja radionuklida renijuma (186Re i 188Re) sa posebnim naglaskom na 188W/ 188Re generatoru. Dati su hemijski oblici i indikacije za primenu nekih radioaktivnih lekova obeleženih ovim radionuklidima. Prikazana su istraživanja sprovedena u Laboratoriji za radioizotope (Institut za nuklearne nauke «Vinča»).",
journal = "Facta Universitatis, Series: Physics, Chemistry and Technology",
title = "Radionuclidic generators for the production of technetium-99m and rhenium-188, Radionuklidni generatori za dobijanje tehnecijuma-99m i renijuma-188",
volume = "2",
number = "4",
pages = "235-243",
doi = "10.2298/FUPCT0204235V"
}

Vučina, J. L.,& Lukić, D. M.. (2002). Radionuclidic generators for the production of technetium-99m and rhenium-188. in Facta Universitatis, Series: Physics, Chemistry and Technology, 2(4), 235-243.
https://doi.org/10.2298/FUPCT0204235V

Vučina JL, Lukić DM. Radionuclidic generators for the production of technetium-99m and rhenium-188. in Facta Universitatis, Series: Physics, Chemistry and Technology. 2002;2(4):235-243.
doi:10.2298/FUPCT0204235V .

Vučina, Jurij L., Lukić, Dragoljub M., "Radionuclidic generators for the production of technetium-99m and rhenium-188" in Facta Universitatis, Series: Physics, Chemistry and Technology, 2, no. 4 (2002):235-243,
https://doi.org/10.2298/FUPCT0204235V . .

TY  - JOUR
AU  - Vučina, Jurij L.
AU  - Vukićević, Nadežda
PY  - 2001
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2469
AB  - The reliability and applicability of the preparation of the three, for nuclear medicine very important, Tc-99m-radiopharmaceuticals from the inactive (technetium-cold) kit solutions were tested. Each examined commercial kit was dissolved in saline (0.9 % NaCl). The conditions of the storage of the inactive kit solutions till labeling were examined. The main problem is the stablity of the reductant stannous ions which is very difficult to predict. To stabilize and ensure a good quality of the labeled radiopharmaceuticals, ascorbic or gentisic acid were added. It was found that the best results were obtained by keeping the samples frozen at-20 degreesC. Both stabilizers can be used but for an effective protection much lower concentrations of ascorbic acid are needed. Its concentrations of 12-60 mug/ml of the kit, stabilized dimercaptosuccinate (DMS) and pyrophosphate (PyP) for about 7-8 days. The solution of 2,3-dicarboxypropane- 1,1-diphosphonate (DPD) was found to be stable even without the stabilizer. This could be attributed probably to the chemical nature of this complex. However, in routine praxis the applied procedure demands great care and personel very experienced in radiopharmacy.
T2  - Journal of the Serbian Chemical Society
T1  - Stabilization of Tc-99m radiopharmaceuticals by chemical additives
VL  - 66
IS  - 9
SP  - 591
EP  - 596
DO  - 10.2298/JSC0109591V
ER  - 

@article{
author = "Vučina, Jurij L. and Vukićević, Nadežda",
year = "2001",
abstract = "The reliability and applicability of the preparation of the three, for nuclear medicine very important, Tc-99m-radiopharmaceuticals from the inactive (technetium-cold) kit solutions were tested. Each examined commercial kit was dissolved in saline (0.9 % NaCl). The conditions of the storage of the inactive kit solutions till labeling were examined. The main problem is the stablity of the reductant stannous ions which is very difficult to predict. To stabilize and ensure a good quality of the labeled radiopharmaceuticals, ascorbic or gentisic acid were added. It was found that the best results were obtained by keeping the samples frozen at-20 degreesC. Both stabilizers can be used but for an effective protection much lower concentrations of ascorbic acid are needed. Its concentrations of 12-60 mug/ml of the kit, stabilized dimercaptosuccinate (DMS) and pyrophosphate (PyP) for about 7-8 days. The solution of 2,3-dicarboxypropane- 1,1-diphosphonate (DPD) was found to be stable even without the stabilizer. This could be attributed probably to the chemical nature of this complex. However, in routine praxis the applied procedure demands great care and personel very experienced in radiopharmacy.",
journal = "Journal of the Serbian Chemical Society",
title = "Stabilization of Tc-99m radiopharmaceuticals by chemical additives",
volume = "66",
number = "9",
pages = "591-596",
doi = "10.2298/JSC0109591V"
}

Vučina, J. L.,& Vukićević, N.. (2001). Stabilization of Tc-99m radiopharmaceuticals by chemical additives. in Journal of the Serbian Chemical Society, 66(9), 591-596.
https://doi.org/10.2298/JSC0109591V

Vučina JL, Vukićević N. Stabilization of Tc-99m radiopharmaceuticals by chemical additives. in Journal of the Serbian Chemical Society. 2001;66(9):591-596.
doi:10.2298/JSC0109591V .

Vučina, Jurij L., Vukićević, Nadežda, "Stabilization of Tc-99m radiopharmaceuticals by chemical additives" in Journal of the Serbian Chemical Society, 66, no. 9 (2001):591-596,
https://doi.org/10.2298/JSC0109591V . .

TY  - JOUR
AU  - Maksin, Tatjana N.
AU  - Vučina, Jurij L.
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
PY  - 2000
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2363
AB  - The results of the quality control of Tc-99m-DPD produced during five consequtive years are statistically evaluated. Radiochemical purity of the kit determined in 75 batches was 98.3+/-1.3%. TLC on silica gel with the mixture of acetone and methanole (1:1, v/v) was used to determine the content of free pertechnetate. The labeled complex and Tc-99m-hydrolyzate was separated by using ascending paper (Schleicher and Schull) chromatography and 1N NaCl as the mobile phase. Reliable results were obtained showing that the content of the impurities Tc-99m-pertechnetate and Tc-99m-hydrolyzate is 1.7+/-1.3% and 3.4+/-2.1%, respectively. The biodistribution depends on the quantity of DPD. For the animal experiments its content should be 70-80 mu g/kg b.w. The experiments revealed that the mean value of bone distribution was 8.8+/-1.9%/g and in muscles 0.043+/-0.042%/g. The uptake in liver and kidneys was below 3%, i.e., 0.65+/-0.29 and 1.71+/-0.68%/organ, respectively. The bone/muscle ratio should be at least 160. The analysis shows that the obtained values are arranged around their, statistically allowed, mean values.
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - Statistical evaluation of the quality control results of Tc-99m(Sn)-DPD
VL  - 243
IS  - 3
SP  - 669
EP  - 671
DO  - 10.1023/A:1010614101992
ER  - 

@article{
author = "Maksin, Tatjana N. and Vučina, Jurij L. and Đokić, Divna Đ. and Janković, Drina",
year = "2000",
abstract = "The results of the quality control of Tc-99m-DPD produced during five consequtive years are statistically evaluated. Radiochemical purity of the kit determined in 75 batches was 98.3+/-1.3%. TLC on silica gel with the mixture of acetone and methanole (1:1, v/v) was used to determine the content of free pertechnetate. The labeled complex and Tc-99m-hydrolyzate was separated by using ascending paper (Schleicher and Schull) chromatography and 1N NaCl as the mobile phase. Reliable results were obtained showing that the content of the impurities Tc-99m-pertechnetate and Tc-99m-hydrolyzate is 1.7+/-1.3% and 3.4+/-2.1%, respectively. The biodistribution depends on the quantity of DPD. For the animal experiments its content should be 70-80 mu g/kg b.w. The experiments revealed that the mean value of bone distribution was 8.8+/-1.9%/g and in muscles 0.043+/-0.042%/g. The uptake in liver and kidneys was below 3%, i.e., 0.65+/-0.29 and 1.71+/-0.68%/organ, respectively. The bone/muscle ratio should be at least 160. The analysis shows that the obtained values are arranged around their, statistically allowed, mean values.",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "Statistical evaluation of the quality control results of Tc-99m(Sn)-DPD",
volume = "243",
number = "3",
pages = "669-671",
doi = "10.1023/A:1010614101992"
}

Maksin, T. N., Vučina, J. L., Đokić, D. Đ.,& Janković, D.. (2000). Statistical evaluation of the quality control results of Tc-99m(Sn)-DPD. in Journal of Radioanalytical and Nuclear Chemistry, 243(3), 669-671.
https://doi.org/10.1023/A:1010614101992

Maksin TN, Vučina JL, Đokić DĐ, Janković D. Statistical evaluation of the quality control results of Tc-99m(Sn)-DPD. in Journal of Radioanalytical and Nuclear Chemistry. 2000;243(3):669-671.
doi:10.1023/A:1010614101992 .

Maksin, Tatjana N., Vučina, Jurij L., Đokić, Divna Đ., Janković, Drina, "Statistical evaluation of the quality control results of Tc-99m(Sn)-DPD" in Journal of Radioanalytical and Nuclear Chemistry, 243, no. 3 (2000):669-671,
https://doi.org/10.1023/A:1010614101992 . .

TY  - JOUR
AU  - Vučina, Jurij L.
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2257
AB  - The in vitro stability of Tc-99m(Sn)-pyrophosphate solution was examined in dependence on the preparation conditions of the samples, the radioactive concentration of Tc-99m in the kit and the time elapsed after labeling. The samples without any protection are highly unstable. The formation of Tc-99m-pertechnetate does not depend on the radioactive concentration. Nitrogen purging provides protection in the case of low radioactive concentrations (37 MBq Tc-99m/ml) but exhibits no effect at higher concentrations. The best stabilization was achieved by using ascorbic acid. A concentration of 60 mu g/ml keeps the content of Tc-99m-pertechnetate below 1% during six hours after labeling, even in solutions of high radioactive concentrations (740-814 MBq/ml). Gentisic acid is less effective. Concentrations about ten times higher than required using ascorbic acid are needed to keep the content of Tc-99m-pertechnetate below 5% during six hours.
T2  - Journal of the Serbian Chemical Society
T1  - Influence of the radioactive concentration of the in vitro stability of Tc-99m(Sn)-pyrophosphate
VL  - 64
IS  - 5-6
SP  - 375
EP  - 380
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2257
ER  - 

@article{
author = "Vučina, Jurij L.",
year = "1999",
abstract = "The in vitro stability of Tc-99m(Sn)-pyrophosphate solution was examined in dependence on the preparation conditions of the samples, the radioactive concentration of Tc-99m in the kit and the time elapsed after labeling. The samples without any protection are highly unstable. The formation of Tc-99m-pertechnetate does not depend on the radioactive concentration. Nitrogen purging provides protection in the case of low radioactive concentrations (37 MBq Tc-99m/ml) but exhibits no effect at higher concentrations. The best stabilization was achieved by using ascorbic acid. A concentration of 60 mu g/ml keeps the content of Tc-99m-pertechnetate below 1% during six hours after labeling, even in solutions of high radioactive concentrations (740-814 MBq/ml). Gentisic acid is less effective. Concentrations about ten times higher than required using ascorbic acid are needed to keep the content of Tc-99m-pertechnetate below 5% during six hours.",
journal = "Journal of the Serbian Chemical Society",
title = "Influence of the radioactive concentration of the in vitro stability of Tc-99m(Sn)-pyrophosphate",
volume = "64",
number = "5-6",
pages = "375-380",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2257"
}

Vučina, J. L.. (1999). Influence of the radioactive concentration of the in vitro stability of Tc-99m(Sn)-pyrophosphate. in Journal of the Serbian Chemical Society, 64(5-6), 375-380.
https://hdl.handle.net/21.15107/rcub_vinar_2257

Vučina JL. Influence of the radioactive concentration of the in vitro stability of Tc-99m(Sn)-pyrophosphate. in Journal of the Serbian Chemical Society. 1999;64(5-6):375-380.
https://hdl.handle.net/21.15107/rcub_vinar_2257 .

Vučina, Jurij L., "Influence of the radioactive concentration of the in vitro stability of Tc-99m(Sn)-pyrophosphate" in Journal of the Serbian Chemical Society, 64, no. 5-6 (1999):375-380,
https://hdl.handle.net/21.15107/rcub_vinar_2257 .

TY  - JOUR
AU  - Vučina, Jurij L.
PY  - 1998
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2138
T2  - Journal of the Serbian Chemical Society
T1  - Technetium-99m production: Available options and future prospects
VL  - 63
IS  - 5
SP  - 319
EP  - 347
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2138
ER  - 

@article{
author = "Vučina, Jurij L.",
year = "1998",
journal = "Journal of the Serbian Chemical Society",
title = "Technetium-99m production: Available options and future prospects",
volume = "63",
number = "5",
pages = "319-347",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2138"
}

Vučina, J. L.. (1998). Technetium-99m production: Available options and future prospects. in Journal of the Serbian Chemical Society, 63(5), 319-347.
https://hdl.handle.net/21.15107/rcub_vinar_2138

Vučina JL. Technetium-99m production: Available options and future prospects. in Journal of the Serbian Chemical Society. 1998;63(5):319-347.
https://hdl.handle.net/21.15107/rcub_vinar_2138 .

Vučina, Jurij L., "Technetium-99m production: Available options and future prospects" in Journal of the Serbian Chemical Society, 63, no. 5 (1998):319-347,
https://hdl.handle.net/21.15107/rcub_vinar_2138 .

TY  - JOUR
AU  - Vučina, Jurij L.
PY  - 1998
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2115
AB  - The cold solution of a pyrophosphate kit was prepared and dispensed into 2-ml fractions which were stored at -20 degrees C for one week. The solution was prepared by using two protection methods. The first was nitrogen purging to exclude air and the second one the addition of the well known antioxydant ascorbic acid. The aim was to determine the stability of Tc-99m(Sn)-PyP obtained by labeling these fractions prepared under the given experimental conditions. The content of Tc-99m-pertechnetate in the unprotected samples raises with time. Nitrogen purging provides some protection but already after a few days the content of pertechnetate exceeds 5%. The addition of ascorbic acid gave good results. The content of pertechnetate was 1-2% after seven days in the presence of 50 mu g of acid per mi of the cold kit.
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - Stability of fractionated technetium-cold pyrophosphate solution
VL  - 227
IS  - 1-2
SP  - 167
EP  - 169
DO  - 10.1007/BF02386453
ER  - 

@article{
author = "Vučina, Jurij L.",
year = "1998",
abstract = "The cold solution of a pyrophosphate kit was prepared and dispensed into 2-ml fractions which were stored at -20 degrees C for one week. The solution was prepared by using two protection methods. The first was nitrogen purging to exclude air and the second one the addition of the well known antioxydant ascorbic acid. The aim was to determine the stability of Tc-99m(Sn)-PyP obtained by labeling these fractions prepared under the given experimental conditions. The content of Tc-99m-pertechnetate in the unprotected samples raises with time. Nitrogen purging provides some protection but already after a few days the content of pertechnetate exceeds 5%. The addition of ascorbic acid gave good results. The content of pertechnetate was 1-2% after seven days in the presence of 50 mu g of acid per mi of the cold kit.",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "Stability of fractionated technetium-cold pyrophosphate solution",
volume = "227",
number = "1-2",
pages = "167-169",
doi = "10.1007/BF02386453"
}

Vučina, J. L.. (1998). Stability of fractionated technetium-cold pyrophosphate solution. in Journal of Radioanalytical and Nuclear Chemistry, 227(1-2), 167-169.
https://doi.org/10.1007/BF02386453

Vučina JL. Stability of fractionated technetium-cold pyrophosphate solution. in Journal of Radioanalytical and Nuclear Chemistry. 1998;227(1-2):167-169.
doi:10.1007/BF02386453 .

Vučina, Jurij L., "Stability of fractionated technetium-cold pyrophosphate solution" in Journal of Radioanalytical and Nuclear Chemistry, 227, no. 1-2 (1998):167-169,
https://doi.org/10.1007/BF02386453 . .

TY  - JOUR
AU  - Đokić, Divna Đ.
AU  - Maksin, Tatjana N.
AU  - Vučina, Jurij L.
AU  - Janković, Drina
PY  - 1998
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2218
AB  - A modified Tc-99m(Sn)-pyrophosphate (PyP) kit for the application in nuclear cardiology (radioventriculography, angiocardiography, scintigraphy of blood pool) was developed. Each vial contains 12 mg PyP (Na4P2O7), 4 mg SnCl2. 2H(2)O, 2.5 mg gentisic acid and IO mg NaCl. The reconstitution is performed by dissolving the lyophilized kit in 3 mi 0.9% NaCl. In comparison with the standard pyrophosphate kit for bone scanning and detection of miocardial infarction, it contains an increased amount of Sn(Il) so that the molar ratio ligand/reductant is lowered from 25 to 2.5. The radiochemical analyses showed that the radiochemical purity of the labeled kit is high ( GT 90%) during three hours after addition of Tc-99m-activity. The shelf-life of the inactive freeze-dried preparation is up to four months providing that it is kept in vacuum and at appropriate temperature (2-8 degrees C). The biodistribution studies revealed increased accumulation in blood and low uptake by liver and kidneys. It was concluded that the modified kit performs stable and reproducible properties.
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - Modified pyrophosphate-Tc-99m kit for application in nuclear cardiology
VL  - 238
IS  - 1-2
SP  - 155
EP  - 157
DO  - 10.1007/BF02385372
ER  - 

@article{
author = "Đokić, Divna Đ. and Maksin, Tatjana N. and Vučina, Jurij L. and Janković, Drina",
year = "1998",
abstract = "A modified Tc-99m(Sn)-pyrophosphate (PyP) kit for the application in nuclear cardiology (radioventriculography, angiocardiography, scintigraphy of blood pool) was developed. Each vial contains 12 mg PyP (Na4P2O7), 4 mg SnCl2. 2H(2)O, 2.5 mg gentisic acid and IO mg NaCl. The reconstitution is performed by dissolving the lyophilized kit in 3 mi 0.9% NaCl. In comparison with the standard pyrophosphate kit for bone scanning and detection of miocardial infarction, it contains an increased amount of Sn(Il) so that the molar ratio ligand/reductant is lowered from 25 to 2.5. The radiochemical analyses showed that the radiochemical purity of the labeled kit is high ( GT 90%) during three hours after addition of Tc-99m-activity. The shelf-life of the inactive freeze-dried preparation is up to four months providing that it is kept in vacuum and at appropriate temperature (2-8 degrees C). The biodistribution studies revealed increased accumulation in blood and low uptake by liver and kidneys. It was concluded that the modified kit performs stable and reproducible properties.",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "Modified pyrophosphate-Tc-99m kit for application in nuclear cardiology",
volume = "238",
number = "1-2",
pages = "155-157",
doi = "10.1007/BF02385372"
}

Đokić, D. Đ., Maksin, T. N., Vučina, J. L.,& Janković, D.. (1998). Modified pyrophosphate-Tc-99m kit for application in nuclear cardiology. in Journal of Radioanalytical and Nuclear Chemistry, 238(1-2), 155-157.
https://doi.org/10.1007/BF02385372

Đokić DĐ, Maksin TN, Vučina JL, Janković D. Modified pyrophosphate-Tc-99m kit for application in nuclear cardiology. in Journal of Radioanalytical and Nuclear Chemistry. 1998;238(1-2):155-157.
doi:10.1007/BF02385372 .

Đokić, Divna Đ., Maksin, Tatjana N., Vučina, Jurij L., Janković, Drina, "Modified pyrophosphate-Tc-99m kit for application in nuclear cardiology" in Journal of Radioanalytical and Nuclear Chemistry, 238, no. 1-2 (1998):155-157,
https://doi.org/10.1007/BF02385372 . .

TY  - JOUR
AU  - Vučina, Jurij L.
AU  - Marković, Mirjana
AU  - Kukoč, A. H.
PY  - 1996
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1966
AB  - The long-lived gamma-radionuclidic impurities in the columns of spent Mo-99/Tc-99m generators one year after the calibration date have been determined by v-spectrometry. Three radionuclidic impurities fission products (Ru-103, Ru-106 and Sb-125) were detected. Also in the majority of samples, three radioisotopes of tungsten (W-181, W-185 and W-188) were also present. The contents of the impurities were found to vary,greatly. According to the activity, energy and half-life, the main contribution to the residual activity in the spent generators is due to the presence of Sb-125.
T2  - Journal of Radioanalytical and Nuclear Chemistry - Letters
T1  - Long-lived gamma-radionuclidic impurities in spent Mo-99/Tc-99m generators
VL  - 212
IS  - 3
SP  - 221
EP  - 227
DO  - 10.1007/BF02162229
ER  - 

@article{
author = "Vučina, Jurij L. and Marković, Mirjana and Kukoč, A. H.",
year = "1996",
abstract = "The long-lived gamma-radionuclidic impurities in the columns of spent Mo-99/Tc-99m generators one year after the calibration date have been determined by v-spectrometry. Three radionuclidic impurities fission products (Ru-103, Ru-106 and Sb-125) were detected. Also in the majority of samples, three radioisotopes of tungsten (W-181, W-185 and W-188) were also present. The contents of the impurities were found to vary,greatly. According to the activity, energy and half-life, the main contribution to the residual activity in the spent generators is due to the presence of Sb-125.",
journal = "Journal of Radioanalytical and Nuclear Chemistry - Letters",
title = "Long-lived gamma-radionuclidic impurities in spent Mo-99/Tc-99m generators",
volume = "212",
number = "3",
pages = "221-227",
doi = "10.1007/BF02162229"
}

Vučina, J. L., Marković, M.,& Kukoč, A. H.. (1996). Long-lived gamma-radionuclidic impurities in spent Mo-99/Tc-99m generators. in Journal of Radioanalytical and Nuclear Chemistry - Letters, 212(3), 221-227.
https://doi.org/10.1007/BF02162229

Vučina JL, Marković M, Kukoč AH. Long-lived gamma-radionuclidic impurities in spent Mo-99/Tc-99m generators. in Journal of Radioanalytical and Nuclear Chemistry - Letters. 1996;212(3):221-227.
doi:10.1007/BF02162229 .

Vučina, Jurij L., Marković, Mirjana, Kukoč, A. H., "Long-lived gamma-radionuclidic impurities in spent Mo-99/Tc-99m generators" in Journal of Radioanalytical and Nuclear Chemistry - Letters, 212, no. 3 (1996):221-227,
https://doi.org/10.1007/BF02162229 . .

TY  - JOUR
AU  - Vučina, Jurij L.
PY  - 1996
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2044
AB  - The effect of the preparation conditions on the in vitro stability of Tc-99m(Sn)-pyrophosphate kit solution has been examined. To extend the shelf-life of the preparation, different methods of protection were tested. Nitrogen purging stabilizes the kit for at least 6 h after labeling when the content of (99)mTc-pertechnetate raises to about 5%. However, this method is ineffective in the presence of hydrogen peroxide. The protecting ability of two chemicals was also determined. Gentisic acid gave good results. In the presence of 50 mu g of gentisic acid per mi of the kit the content of pertechnetate was 1-2% throughout the examined time interval. To eliminate the influence of hydrogen peroxide (6 mu g per ml of the kit) about 100 mu g of gentisic acid is needed. N,N-diphenyl-p-phenylenediamine (DPPD) performs some protecting effect only when used in the samples protected by nitrogen purging. However its protecting ability is lower that in the case of gentisic acid.
T2  - Journal of Radioanalytical and Nuclear Chemistry - Letters
T1  - Shelf-life of Tc-99m(Sn)-pyrophosphate
VL  - 214
IS  - 1
SP  - 29
EP  - 39
DO  - 10.1007/BF02165056
ER  - 

@article{
author = "Vučina, Jurij L.",
year = "1996",
abstract = "The effect of the preparation conditions on the in vitro stability of Tc-99m(Sn)-pyrophosphate kit solution has been examined. To extend the shelf-life of the preparation, different methods of protection were tested. Nitrogen purging stabilizes the kit for at least 6 h after labeling when the content of (99)mTc-pertechnetate raises to about 5%. However, this method is ineffective in the presence of hydrogen peroxide. The protecting ability of two chemicals was also determined. Gentisic acid gave good results. In the presence of 50 mu g of gentisic acid per mi of the kit the content of pertechnetate was 1-2% throughout the examined time interval. To eliminate the influence of hydrogen peroxide (6 mu g per ml of the kit) about 100 mu g of gentisic acid is needed. N,N-diphenyl-p-phenylenediamine (DPPD) performs some protecting effect only when used in the samples protected by nitrogen purging. However its protecting ability is lower that in the case of gentisic acid.",
journal = "Journal of Radioanalytical and Nuclear Chemistry - Letters",
title = "Shelf-life of Tc-99m(Sn)-pyrophosphate",
volume = "214",
number = "1",
pages = "29-39",
doi = "10.1007/BF02165056"
}

Vučina, J. L.. (1996). Shelf-life of Tc-99m(Sn)-pyrophosphate. in Journal of Radioanalytical and Nuclear Chemistry - Letters, 214(1), 29-39.
https://doi.org/10.1007/BF02165056

Vučina JL. Shelf-life of Tc-99m(Sn)-pyrophosphate. in Journal of Radioanalytical and Nuclear Chemistry - Letters. 1996;214(1):29-39.
doi:10.1007/BF02165056 .

Vučina, Jurij L., "Shelf-life of Tc-99m(Sn)-pyrophosphate" in Journal of Radioanalytical and Nuclear Chemistry - Letters, 214, no. 1 (1996):29-39,
https://doi.org/10.1007/BF02165056 . .

TY  - JOUR
AU  - Vučina, Jurij L.
PY  - 1996
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1985
AB  - The in vitro stability of Tc-99m(Sn)-PyP as a function of experimental conditions of the preparation of the kit and time elapsed after labeling has been tested. The preparation was protected by using nitrogen-purged reactant solutions and kit vials and by ascorbic acid. The samples under nitrogen are stable for 6 h when the content of Tc-99m-pertechnetate raises to 5%. The best stability was achieved by addition of 5 mu g of ascorbic acid per ml of the kit (content of Tc-99m-pertechnetate about 0.5%). To accelerate the decomposition, exogenous hydrogen peroxide was used. In this case it was found that the presence of 10 mu g of ascorbic acid inhibits the effect both of oxygen and peroxide (6 mu g H2O2/ml of the kit). Radiochemically purity of 99mTc(Sn)-PyP remains practically unchanged for 6 h (content of Tc-99m-pertechnetate about 0.5%).
T2  - Journal of Radioanalytical and Nuclear Chemistry - Letters
T1  - Effect of experimental conditions on the in vitro stability of Tc-99m(Sn)-pyrophosphate
VL  - 212
IS  - 5
SP  - 333
EP  - 340
DO  - 10.1007/BF02162648
ER  - 

@article{
author = "Vučina, Jurij L.",
year = "1996",
abstract = "The in vitro stability of Tc-99m(Sn)-PyP as a function of experimental conditions of the preparation of the kit and time elapsed after labeling has been tested. The preparation was protected by using nitrogen-purged reactant solutions and kit vials and by ascorbic acid. The samples under nitrogen are stable for 6 h when the content of Tc-99m-pertechnetate raises to 5%. The best stability was achieved by addition of 5 mu g of ascorbic acid per ml of the kit (content of Tc-99m-pertechnetate about 0.5%). To accelerate the decomposition, exogenous hydrogen peroxide was used. In this case it was found that the presence of 10 mu g of ascorbic acid inhibits the effect both of oxygen and peroxide (6 mu g H2O2/ml of the kit). Radiochemically purity of 99mTc(Sn)-PyP remains practically unchanged for 6 h (content of Tc-99m-pertechnetate about 0.5%).",
journal = "Journal of Radioanalytical and Nuclear Chemistry - Letters",
title = "Effect of experimental conditions on the in vitro stability of Tc-99m(Sn)-pyrophosphate",
volume = "212",
number = "5",
pages = "333-340",
doi = "10.1007/BF02162648"
}

Vučina, J. L.. (1996). Effect of experimental conditions on the in vitro stability of Tc-99m(Sn)-pyrophosphate. in Journal of Radioanalytical and Nuclear Chemistry - Letters, 212(5), 333-340.
https://doi.org/10.1007/BF02162648

Vučina JL. Effect of experimental conditions on the in vitro stability of Tc-99m(Sn)-pyrophosphate. in Journal of Radioanalytical and Nuclear Chemistry - Letters. 1996;212(5):333-340.
doi:10.1007/BF02162648 .

Vučina, Jurij L., "Effect of experimental conditions on the in vitro stability of Tc-99m(Sn)-pyrophosphate" in Journal of Radioanalytical and Nuclear Chemistry - Letters, 212, no. 5 (1996):333-340,
https://doi.org/10.1007/BF02162648 . .