TY  - JOUR
AU  - Micić, Milutin
AU  - Antonijević, Đorđe
AU  - Milutinović-Smiljanić, Sanja
AU  - Trišić, Dijana
AU  - Čolović, Božana M.
AU  - Kosanović, Dejana
AU  - Prokić, Bogomir Bolka
AU  - Vasić, Jugoslav
AU  - Živković, Slavoljub
AU  - Milašin, Jelena
AU  - Danilović, Vesna
AU  - Đurić, Marija P.
AU  - Jokanović, Vukoman R.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10363
AB  - Article Corrigendum to: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit’s ulna reconstruction was published on June 28, 2022 in the journal Biomedical Engineering / Biomedizinische Technik
T2  - Biomedical Engineering / Biomedizinische Technik
T1  - Corrigendum: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction (Biomedical Engineering / Biomedizinische Technik 65:4 (491-505) DOI: 10.1515/bmt-2019-0218)
DO  - 10.1515/bmt-2022-0188
ER  - 

@article{
author = "Micić, Milutin and Antonijević, Đorđe and Milutinović-Smiljanić, Sanja and Trišić, Dijana and Čolović, Božana M. and Kosanović, Dejana and Prokić, Bogomir Bolka and Vasić, Jugoslav and Živković, Slavoljub and Milašin, Jelena and Danilović, Vesna and Đurić, Marija P. and Jokanović, Vukoman R.",
year = "2022",
abstract = "Article Corrigendum to: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit’s ulna reconstruction was published on June 28, 2022 in the journal Biomedical Engineering / Biomedizinische Technik",
journal = "Biomedical Engineering / Biomedizinische Technik",
title = "Corrigendum: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction (Biomedical Engineering / Biomedizinische Technik 65:4 (491-505) DOI: 10.1515/bmt-2019-0218)",
doi = "10.1515/bmt-2022-0188"
}

Micić, M., Antonijević, Đ., Milutinović-Smiljanić, S., Trišić, D., Čolović, B. M., Kosanović, D., Prokić, B. B., Vasić, J., Živković, S., Milašin, J., Danilović, V., Đurić, M. P.,& Jokanović, V. R.. (2022). Corrigendum: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction (Biomedical Engineering / Biomedizinische Technik 65:4 (491-505) DOI: 10.1515/bmt-2019-0218). in Biomedical Engineering / Biomedizinische Technik.
https://doi.org/10.1515/bmt-2022-0188

Micić M, Antonijević Đ, Milutinović-Smiljanić S, Trišić D, Čolović BM, Kosanović D, Prokić BB, Vasić J, Živković S, Milašin J, Danilović V, Đurić MP, Jokanović VR. Corrigendum: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction (Biomedical Engineering / Biomedizinische Technik 65:4 (491-505) DOI: 10.1515/bmt-2019-0218). in Biomedical Engineering / Biomedizinische Technik. 2022;.
doi:10.1515/bmt-2022-0188 .

Micić, Milutin, Antonijević, Đorđe, Milutinović-Smiljanić, Sanja, Trišić, Dijana, Čolović, Božana M., Kosanović, Dejana, Prokić, Bogomir Bolka, Vasić, Jugoslav, Živković, Slavoljub, Milašin, Jelena, Danilović, Vesna, Đurić, Marija P., Jokanović, Vukoman R., "Corrigendum: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction (Biomedical Engineering / Biomedizinische Technik 65:4 (491-505) DOI: 10.1515/bmt-2019-0218)" in Biomedical Engineering / Biomedizinische Technik (2022),
https://doi.org/10.1515/bmt-2022-0188 . .

TY  - JOUR
AU  - Milutinović-Smiljanić, Sanja
AU  - Antonijević, Đorđe
AU  - Mićić, Milutin
AU  - Biočanin, Vladimir
AU  - Sjerobabin, Nikola
AU  - Petrović, Božana
AU  - Danilović, Vesna
AU  - Jokanović, Vukoman R.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11221
AB  - Background/Aim. The materials used nowadays for bone replacement do not fully meet the requirements for complete regeneration, which is why new ones are being tested. Despite numerous attempts to improve bone tissue regeneration, no fulfilling material has been found yet. This study investigated the influence of poly-lactide-co-glycolide (PLGA) and polyethyleneimine (PEI) as coatings for hydroxyapatite (HAP) bone carriers on bone tissue regenerative potential in rabbits? calvarial defect. Methods. Calvarial defects measuring 6 mm in diameter were made in 19 skeletally mature rabbits. Defects were filled with one of the following materials: PLGA coated HAP (HAP + PLGA), PEI coated HAP (HAP + PEI), and bovine HAP ? Bio-Oss? (positive control). Unfilled defects represented negative control. Histological analysis was performed in order to determine the inflammatory response of the host tissue. The formation of the new bone was evaluated using histomorphometric analysis. All analyses have been conducted in samples obtained 3, 6, and 9 weeks after implantation. Results. Three weeks post-implantation, a trend toward increased healing in the HAP + PLGA group compared to other investigated materials was noticed, with no statistically significant difference between the study groups (p > 0.05). However, after 6 and 9 weeks, significant healing was observed in favor of the HAP coated with PLGA compared to other groups (p
AB  - Uvod/Cilj. Materijali koji se u današnje vreme koriste za nadoknadu koštanog tkiva ne dovode do kompletne regeneracije, zbog čega se ispituju novi. Uprkos mnogobrojnim pokušajima da se poboljša regeneracija koštanog tkiva, još uvek nije pronađen materijal koji ispunjava sve kriterijume. Cilj rada bio je da se utvrdi uticaj poli(laktid-ko-glikolida) (PLGA) i polietilenimina (PEI), kao premaza za oblaganje hidroksiapatita (HAP), na regenerativni potencijal koštanog tkiva u defektu kalvarije zeca. Metode. Kod 19 zečeva „zrelog” skeleta načinjeni su defekti kalvarije dijametra 6 mm. Defekti su potom ispunjeni jednim od sledećih materijala: HAP obložen PLGA (HAP + PLGA), HAP obložen PEI (HAP + PEI) i goveđi HAP – Bio-Oss® (pozitivna kontrola). Prazni defekti su predstavljali negativnu kontrolu. Inflamacijska reakcija tkiva domaćina je ispitana histološkom analizom. Formiranje nove kosti je procenjivano histomorfometrijskom analizom. Analizirani su uzorci dobijeni 3, 6 i 9 nedelja nakon implantacije. Rezultati. Tri nedelje nakon implantacije, uočena je tendencija boljeg zarastanja u HAP + PLGA grupi, bez statistički značajne razlike između ispitivanih grupa (p > 0.05). Međutim, 6 i 9 nedelja nakon implantacije, primećeno je značajno formiranje koštanog tkiva u korist HAP + PLGA grupe (p < 0,05). Oblaganje HAP sa PLGA dovelo je do boljeg koštanog zarastanja u poređenju sa HAP+PEI i Bio-Oss®. Zaključak. U pogledu stimulisanja osteogeneze u rekonstruktivnoj hirurgiji kostiju, PLGA je pokazao veći potencijal prekrivanja defekta od PEI.
T2  - Vojnosanitetski pregled
T1  - The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis
T1  - Uticaj različitih materijala koji oblažu hidroksiapatit koštanog nosača na uspeh regeneracije koštanih defekta kalvarije zeca: histomorfometrijska i histološka analiza
VL  - 79
IS  - 10
SP  - 1025
EP  - 1034
DO  - 10.2298/VSP210513072M
ER  - 

@article{
author = "Milutinović-Smiljanić, Sanja and Antonijević, Đorđe and Mićić, Milutin and Biočanin, Vladimir and Sjerobabin, Nikola and Petrović, Božana and Danilović, Vesna and Jokanović, Vukoman R.",
year = "2022",
abstract = "Background/Aim. The materials used nowadays for bone replacement do not fully meet the requirements for complete regeneration, which is why new ones are being tested. Despite numerous attempts to improve bone tissue regeneration, no fulfilling material has been found yet. This study investigated the influence of poly-lactide-co-glycolide (PLGA) and polyethyleneimine (PEI) as coatings for hydroxyapatite (HAP) bone carriers on bone tissue regenerative potential in rabbits? calvarial defect. Methods. Calvarial defects measuring 6 mm in diameter were made in 19 skeletally mature rabbits. Defects were filled with one of the following materials: PLGA coated HAP (HAP + PLGA), PEI coated HAP (HAP + PEI), and bovine HAP ? Bio-Oss? (positive control). Unfilled defects represented negative control. Histological analysis was performed in order to determine the inflammatory response of the host tissue. The formation of the new bone was evaluated using histomorphometric analysis. All analyses have been conducted in samples obtained 3, 6, and 9 weeks after implantation. Results. Three weeks post-implantation, a trend toward increased healing in the HAP + PLGA group compared to other investigated materials was noticed, with no statistically significant difference between the study groups (p > 0.05). However, after 6 and 9 weeks, significant healing was observed in favor of the HAP coated with PLGA compared to other groups (p, Uvod/Cilj. Materijali koji se u današnje vreme koriste za nadoknadu koštanog tkiva ne dovode do kompletne regeneracije, zbog čega se ispituju novi. Uprkos mnogobrojnim pokušajima da se poboljša regeneracija koštanog tkiva, još uvek nije pronađen materijal koji ispunjava sve kriterijume. Cilj rada bio je da se utvrdi uticaj poli(laktid-ko-glikolida) (PLGA) i polietilenimina (PEI), kao premaza za oblaganje hidroksiapatita (HAP), na regenerativni potencijal koštanog tkiva u defektu kalvarije zeca. Metode. Kod 19 zečeva „zrelog” skeleta načinjeni su defekti kalvarije dijametra 6 mm. Defekti su potom ispunjeni jednim od sledećih materijala: HAP obložen PLGA (HAP + PLGA), HAP obložen PEI (HAP + PEI) i goveđi HAP – Bio-Oss® (pozitivna kontrola). Prazni defekti su predstavljali negativnu kontrolu. Inflamacijska reakcija tkiva domaćina je ispitana histološkom analizom. Formiranje nove kosti je procenjivano histomorfometrijskom analizom. Analizirani su uzorci dobijeni 3, 6 i 9 nedelja nakon implantacije. Rezultati. Tri nedelje nakon implantacije, uočena je tendencija boljeg zarastanja u HAP + PLGA grupi, bez statistički značajne razlike između ispitivanih grupa (p > 0.05). Međutim, 6 i 9 nedelja nakon implantacije, primećeno je značajno formiranje koštanog tkiva u korist HAP + PLGA grupe (p < 0,05). Oblaganje HAP sa PLGA dovelo je do boljeg koštanog zarastanja u poređenju sa HAP+PEI i Bio-Oss®. Zaključak. U pogledu stimulisanja osteogeneze u rekonstruktivnoj hirurgiji kostiju, PLGA je pokazao veći potencijal prekrivanja defekta od PEI.",
journal = "Vojnosanitetski pregled",
title = "The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis, Uticaj različitih materijala koji oblažu hidroksiapatit koštanog nosača na uspeh regeneracije koštanih defekta kalvarije zeca: histomorfometrijska i histološka analiza",
volume = "79",
number = "10",
pages = "1025-1034",
doi = "10.2298/VSP210513072M"
}

Milutinović-Smiljanić, S., Antonijević, Đ., Mićić, M., Biočanin, V., Sjerobabin, N., Petrović, B., Danilović, V.,& Jokanović, V. R.. (2022). The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis. in Vojnosanitetski pregled, 79(10), 1025-1034.
https://doi.org/10.2298/VSP210513072M

Milutinović-Smiljanić S, Antonijević Đ, Mićić M, Biočanin V, Sjerobabin N, Petrović B, Danilović V, Jokanović VR. The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis. in Vojnosanitetski pregled. 2022;79(10):1025-1034.
doi:10.2298/VSP210513072M .

Milutinović-Smiljanić, Sanja, Antonijević, Đorđe, Mićić, Milutin, Biočanin, Vladimir, Sjerobabin, Nikola, Petrović, Božana, Danilović, Vesna, Jokanović, Vukoman R., "The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis" in Vojnosanitetski pregled, 79, no. 10 (2022):1025-1034,
https://doi.org/10.2298/VSP210513072M . .

TY  - JOUR
AU  - Paraš, Smiljana
AU  - Trišić, Dijana
AU  - Mitrović-Ajtić, Olivera
AU  - Antonijević, Đorđe
AU  - Čolović, Božana M.
AU  - Drobne, Damjana
AU  - Jokanović, Vukoman R.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9821
AB  - The effects of a new material based on hydroxyapatite and calcium silicates, named ALBO-MPCA, were investigated on the liver, kidney and spleen. The material was administrated orally for 120 days in an in vivo model in Wistar rats, and untreated animals served as a control. Hematological and biochemical blood parameters were analyzed. Qualitative histological analysis of tissues, change in mitotic activity of cells, and histological characteristics was conducted, as well as quantitative stereological analysis of parenchymal cells, blood sinusoids, and connective tissues. Additionally, the protein expressions of Ki67 and CD68 markers were evaluated. Histological analysis revealed no pathological changes after the tested period. It showed the preservation of the architecture of blood sinusoids and epithelial cells and the presence of mitosis. Additionally, the significantly increased number of the Ki67 in the presence of ALBO-MPCA confirmed the proliferative effect of the material noticed by stereological analysis, while immunoreactive CD68 positive cells did not differ between groups. The study showed non-toxicity of the tested material based on the effects on the hematological, biochemical, and observed histological parameters; in addition, it showed evidence of its biocompatibility. These results could be the basis for further steps toward the application of tested materials in endodontics.
T2  - International Journal of Molecular Science
T1  - Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects
VL  - 22
IS  - 11
SP  - 5468
DO  - 10.3390/ijms22115468
ER  - 

@article{
author = "Paraš, Smiljana and Trišić, Dijana and Mitrović-Ajtić, Olivera and Antonijević, Đorđe and Čolović, Božana M. and Drobne, Damjana and Jokanović, Vukoman R.",
year = "2021",
abstract = "The effects of a new material based on hydroxyapatite and calcium silicates, named ALBO-MPCA, were investigated on the liver, kidney and spleen. The material was administrated orally for 120 days in an in vivo model in Wistar rats, and untreated animals served as a control. Hematological and biochemical blood parameters were analyzed. Qualitative histological analysis of tissues, change in mitotic activity of cells, and histological characteristics was conducted, as well as quantitative stereological analysis of parenchymal cells, blood sinusoids, and connective tissues. Additionally, the protein expressions of Ki67 and CD68 markers were evaluated. Histological analysis revealed no pathological changes after the tested period. It showed the preservation of the architecture of blood sinusoids and epithelial cells and the presence of mitosis. Additionally, the significantly increased number of the Ki67 in the presence of ALBO-MPCA confirmed the proliferative effect of the material noticed by stereological analysis, while immunoreactive CD68 positive cells did not differ between groups. The study showed non-toxicity of the tested material based on the effects on the hematological, biochemical, and observed histological parameters; in addition, it showed evidence of its biocompatibility. These results could be the basis for further steps toward the application of tested materials in endodontics.",
journal = "International Journal of Molecular Science",
title = "Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects",
volume = "22",
number = "11",
pages = "5468",
doi = "10.3390/ijms22115468"
}

Paraš, S., Trišić, D., Mitrović-Ajtić, O., Antonijević, Đ., Čolović, B. M., Drobne, D.,& Jokanović, V. R.. (2021). Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects. in International Journal of Molecular Science, 22(11), 5468.
https://doi.org/10.3390/ijms22115468

Paraš S, Trišić D, Mitrović-Ajtić O, Antonijević Đ, Čolović BM, Drobne D, Jokanović VR. Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects. in International Journal of Molecular Science. 2021;22(11):5468.
doi:10.3390/ijms22115468 .

Paraš, Smiljana, Trišić, Dijana, Mitrović-Ajtić, Olivera, Antonijević, Đorđe, Čolović, Božana M., Drobne, Damjana, Jokanović, Vukoman R., "Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects" in International Journal of Molecular Science, 22, no. 11 (2021):5468,
https://doi.org/10.3390/ijms22115468 . .

TY  - JOUR
AU  - Milutinović-Smiljanić, Sanja
AU  - Ilić, Dragan
AU  - Danilović, Vesna
AU  - Antonijević, Đorđe
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10030
AB  - Background/Aim. In dentistry, the concept of using inert materials for tissue repair has been replaced by the strategy to find bioactive materials which positively interact with human tissues. The aim of this study was to characterize the physicochemical properties of the commercially available calcium silicate and calcium carbonate-based dental cement, biodentine (Septodont, France). Methods. Material elucidation included the measurements of radiopacity, scanning electron microscopy and x-ray dispersive analyses, wettability, Fourier transform infrared spectroscopy, microindentation, micro- to nanoporosity, setting time, pH and calcium ion release. The cells (mouse bone marrow mesenchymal stem cells – BMSCs) were grown on biodentine surface in order to evaluate its behaviour under biological conditions. Results. The radiopacity of the cement (2.8 mmAl) was below ISO requirement for a root canal filling material. The cement was composed of fine powder with particles similar in size and shape, changing from oval to cubic after having been soaked in a simulated body fluid. Biodentine demonstrated good micromechanical properties and low porosity attributed to microporosity with the average pore size of 92 μm. Wettability (contact angle = 41°), calcium ion release (0.098 μg/cm2) and pH of storage solution (9.07) showed satisfactory characteristics. The BMSCa in intimate contact with cement particles remained viable, indicating biodentine good biocompatibility. Conclusion. Biodentine exhibits good mechanical and physicochemical characteristics, but possesses insufficient radiopacity. © 2021 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.
T2  - Vojnosanitetski pregled
T1  - The advantages and disadvantages of biodentine: satisfactory mechanical properties and radiopacity not meeting ISO standard
VL  - 78
IS  - 9
SP  - 973
EP  - 980
DO  - 10.2298/VSP191212014M
ER  - 

@article{
author = "Milutinović-Smiljanić, Sanja and Ilić, Dragan and Danilović, Vesna and Antonijević, Đorđe",
year = "2021",
abstract = "Background/Aim. In dentistry, the concept of using inert materials for tissue repair has been replaced by the strategy to find bioactive materials which positively interact with human tissues. The aim of this study was to characterize the physicochemical properties of the commercially available calcium silicate and calcium carbonate-based dental cement, biodentine (Septodont, France). Methods. Material elucidation included the measurements of radiopacity, scanning electron microscopy and x-ray dispersive analyses, wettability, Fourier transform infrared spectroscopy, microindentation, micro- to nanoporosity, setting time, pH and calcium ion release. The cells (mouse bone marrow mesenchymal stem cells – BMSCs) were grown on biodentine surface in order to evaluate its behaviour under biological conditions. Results. The radiopacity of the cement (2.8 mmAl) was below ISO requirement for a root canal filling material. The cement was composed of fine powder with particles similar in size and shape, changing from oval to cubic after having been soaked in a simulated body fluid. Biodentine demonstrated good micromechanical properties and low porosity attributed to microporosity with the average pore size of 92 μm. Wettability (contact angle = 41°), calcium ion release (0.098 μg/cm2) and pH of storage solution (9.07) showed satisfactory characteristics. The BMSCa in intimate contact with cement particles remained viable, indicating biodentine good biocompatibility. Conclusion. Biodentine exhibits good mechanical and physicochemical characteristics, but possesses insufficient radiopacity. © 2021 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.",
journal = "Vojnosanitetski pregled",
title = "The advantages and disadvantages of biodentine: satisfactory mechanical properties and radiopacity not meeting ISO standard",
volume = "78",
number = "9",
pages = "973-980",
doi = "10.2298/VSP191212014M"
}

Milutinović-Smiljanić, S., Ilić, D., Danilović, V.,& Antonijević, Đ.. (2021). The advantages and disadvantages of biodentine: satisfactory mechanical properties and radiopacity not meeting ISO standard. in Vojnosanitetski pregled, 78(9), 973-980.
https://doi.org/10.2298/VSP191212014M

Milutinović-Smiljanić S, Ilić D, Danilović V, Antonijević Đ. The advantages and disadvantages of biodentine: satisfactory mechanical properties and radiopacity not meeting ISO standard. in Vojnosanitetski pregled. 2021;78(9):973-980.
doi:10.2298/VSP191212014M .

Milutinović-Smiljanić, Sanja, Ilić, Dragan, Danilović, Vesna, Antonijević, Đorđe, "The advantages and disadvantages of biodentine: satisfactory mechanical properties and radiopacity not meeting ISO standard" in Vojnosanitetski pregled, 78, no. 9 (2021):973-980,
https://doi.org/10.2298/VSP191212014M . .

TY  - JOUR
AU  - Liu, Yaming
AU  - Antonijević, Đorđe
AU  - Li, Ruining
AU  - Fan, Yuxuan
AU  - Dukić, Ksenija
AU  - Mićić, Milutin
AU  - Yu, Genyu
AU  - Li, Zhiyu
AU  - Đurić, Marija
AU  - Fan, Yifang
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10013
AB  - The aim of the present paper is to determine the sex of the individual using three-dimensional geometric and inertial analyses of metatarsal bones. Metatarsals of 60 adult Chinese subjects of both sexes were scanned using Aquilion One-320 Slice CT Scanner. The three-dimensional models of the metatarsals were reconstructed and thereafter a novel software using the center of mass set as the origin and the three principal axes of inertia was employed for model alignment. Eight geometric and inertial variables were assessed: the bone length, bone width, bone height, surface-area-to-volume ratio, bone density and principal moments of inertia around x, y and z axis. Furthermore, the discriminant functions were established using stepwise discriminant function analysis. A cross-validation procedure was performed to evaluate discriminant accuracy of functions. The results indicated that inertial variables exhibit significant sexual dimorphism, especially principal moments of inertia around z axis. The highest dimorphic values were found in surface-area-to-volume ratio, principal moments of inertia around z axis and bone height. The accuracy rate of the discriminant functions for sex determination ranged from 88.3% to 98.3% (88.3% - 98.3% cross-validated). The highest accuracy of function was established based on the 3rd metatarsal bone. This study showed for the first time that the principal moment of inertia of the human bone may be successfully implemented for sex estimation. In conclusion, the sex of the individual can be accurately estimated using a combination of geometric and inertial variables of the metatarsal bones. The accuracy should be further confirmed in a larger sample size and be tested or independently developed for distinct population/age groups before the functions are widely applied in unidentified skeletons in forensic and bioarchaeological contexts.
T2  - Frontiers in Endocrinology
T1  - Study of Sexual Dimorphism in Metatarsal Bones: Geometric and Inertial Analysis of the Three-Dimensional Reconstructed Models
DO  - 10.3389/fendo.2021.734362
ER  - 

@article{
author = "Liu, Yaming and Antonijević, Đorđe and Li, Ruining and Fan, Yuxuan and Dukić, Ksenija and Mićić, Milutin and Yu, Genyu and Li, Zhiyu and Đurić, Marija and Fan, Yifang",
year = "2021",
abstract = "The aim of the present paper is to determine the sex of the individual using three-dimensional geometric and inertial analyses of metatarsal bones. Metatarsals of 60 adult Chinese subjects of both sexes were scanned using Aquilion One-320 Slice CT Scanner. The three-dimensional models of the metatarsals were reconstructed and thereafter a novel software using the center of mass set as the origin and the three principal axes of inertia was employed for model alignment. Eight geometric and inertial variables were assessed: the bone length, bone width, bone height, surface-area-to-volume ratio, bone density and principal moments of inertia around x, y and z axis. Furthermore, the discriminant functions were established using stepwise discriminant function analysis. A cross-validation procedure was performed to evaluate discriminant accuracy of functions. The results indicated that inertial variables exhibit significant sexual dimorphism, especially principal moments of inertia around z axis. The highest dimorphic values were found in surface-area-to-volume ratio, principal moments of inertia around z axis and bone height. The accuracy rate of the discriminant functions for sex determination ranged from 88.3% to 98.3% (88.3% - 98.3% cross-validated). The highest accuracy of function was established based on the 3rd metatarsal bone. This study showed for the first time that the principal moment of inertia of the human bone may be successfully implemented for sex estimation. In conclusion, the sex of the individual can be accurately estimated using a combination of geometric and inertial variables of the metatarsal bones. The accuracy should be further confirmed in a larger sample size and be tested or independently developed for distinct population/age groups before the functions are widely applied in unidentified skeletons in forensic and bioarchaeological contexts.",
journal = "Frontiers in Endocrinology",
title = "Study of Sexual Dimorphism in Metatarsal Bones: Geometric and Inertial Analysis of the Three-Dimensional Reconstructed Models",
doi = "10.3389/fendo.2021.734362"
}

Liu, Y., Antonijević, Đ., Li, R., Fan, Y., Dukić, K., Mićić, M., Yu, G., Li, Z., Đurić, M.,& Fan, Y.. (2021). Study of Sexual Dimorphism in Metatarsal Bones: Geometric and Inertial Analysis of the Three-Dimensional Reconstructed Models. in Frontiers in Endocrinology.
https://doi.org/10.3389/fendo.2021.734362

Liu Y, Antonijević Đ, Li R, Fan Y, Dukić K, Mićić M, Yu G, Li Z, Đurić M, Fan Y. Study of Sexual Dimorphism in Metatarsal Bones: Geometric and Inertial Analysis of the Three-Dimensional Reconstructed Models. in Frontiers in Endocrinology. 2021;.
doi:10.3389/fendo.2021.734362 .

Liu, Yaming, Antonijević, Đorđe, Li, Ruining, Fan, Yuxuan, Dukić, Ksenija, Mićić, Milutin, Yu, Genyu, Li, Zhiyu, Đurić, Marija, Fan, Yifang, "Study of Sexual Dimorphism in Metatarsal Bones: Geometric and Inertial Analysis of the Three-Dimensional Reconstructed Models" in Frontiers in Endocrinology (2021),
https://doi.org/10.3389/fendo.2021.734362 . .

TY  - JOUR
AU  - Micić, Milutin
AU  - Antonijević, Đorđe
AU  - Milutinović-Smiljanić, Sanja
AU  - Trišić, Dijana
AU  - Čolović, Božana M.
AU  - Kosanović, Dejana
AU  - Prokić, Bogomir Bolka
AU  - Vasić, Jugoslav
AU  - Živković, Slavoljub
AU  - Milašin, Jelena
AU  - Danilović, Vesna
AU  - Đurić, Marija P.
AU  - Jokanović, Vukoman R.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8993
AB  - The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the anatomical shape of the natural bone defect. Engineered construct revealed adequate micro-architectural design for successful bone regeneration having a total porosity of 64% and an average pore size of 256 μm. Radiography and micro-CT analysis depicted new bone apposition through the whole length of the reconstructed ulna with a small area of non-resorbed construct in the central area of defect. Histological analysis revealed new bone formation with both endochondral and endesmal type of ossification. Immunohistochemistry analysis depicted the presence of bone formation indicators-bone morphogenetic protein (BMP), osteocalcin (OCN) and osteopontin (OPN) within newly formed bone. Manufactured personalized construct acts as a "smart" responsive biomaterial capable of modulating the functionality and potential for the personalized bone reconstruction on a clinically relevant length scale.
T2  - Biomedizinische Technik
T1  - Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction
VL  - 65
IS  - 4
SP  - 491
EP  - 505
DO  - 10.1515/bmt-2019-0218
ER  - 

@article{
author = "Micić, Milutin and Antonijević, Đorđe and Milutinović-Smiljanić, Sanja and Trišić, Dijana and Čolović, Božana M. and Kosanović, Dejana and Prokić, Bogomir Bolka and Vasić, Jugoslav and Živković, Slavoljub and Milašin, Jelena and Danilović, Vesna and Đurić, Marija P. and Jokanović, Vukoman R.",
year = "2020",
abstract = "The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the anatomical shape of the natural bone defect. Engineered construct revealed adequate micro-architectural design for successful bone regeneration having a total porosity of 64% and an average pore size of 256 μm. Radiography and micro-CT analysis depicted new bone apposition through the whole length of the reconstructed ulna with a small area of non-resorbed construct in the central area of defect. Histological analysis revealed new bone formation with both endochondral and endesmal type of ossification. Immunohistochemistry analysis depicted the presence of bone formation indicators-bone morphogenetic protein (BMP), osteocalcin (OCN) and osteopontin (OPN) within newly formed bone. Manufactured personalized construct acts as a "smart" responsive biomaterial capable of modulating the functionality and potential for the personalized bone reconstruction on a clinically relevant length scale.",
journal = "Biomedizinische Technik",
title = "Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction",
volume = "65",
number = "4",
pages = "491-505",
doi = "10.1515/bmt-2019-0218"
}

Micić, M., Antonijević, Đ., Milutinović-Smiljanić, S., Trišić, D., Čolović, B. M., Kosanović, D., Prokić, B. B., Vasić, J., Živković, S., Milašin, J., Danilović, V., Đurić, M. P.,& Jokanović, V. R.. (2020). Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction. in Biomedizinische Technik, 65(4), 491-505.
https://doi.org/10.1515/bmt-2019-0218

Micić M, Antonijević Đ, Milutinović-Smiljanić S, Trišić D, Čolović BM, Kosanović D, Prokić BB, Vasić J, Živković S, Milašin J, Danilović V, Đurić MP, Jokanović VR. Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction. in Biomedizinische Technik. 2020;65(4):491-505.
doi:10.1515/bmt-2019-0218 .

Micić, Milutin, Antonijević, Đorđe, Milutinović-Smiljanić, Sanja, Trišić, Dijana, Čolović, Božana M., Kosanović, Dejana, Prokić, Bogomir Bolka, Vasić, Jugoslav, Živković, Slavoljub, Milašin, Jelena, Danilović, Vesna, Đurić, Marija P., Jokanović, Vukoman R., "Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction" in Biomedizinische Technik, 65, no. 4 (2020):491-505,
https://doi.org/10.1515/bmt-2019-0218 . .

TY  - JOUR
AU  - Yu, Genyu
AU  - Fan, Yuzhou
AU  - Fan, Yuxuan
AU  - Li, Ruining
AU  - Liu, Yaming
AU  - Antonijević, Đorđe
AU  - Milovanović, Petar
AU  - Zhang, Bo
AU  - Li, Zhiyu
AU  - Đurić, Marija
AU  - Fan, Yifang
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9100
AB  - Hallux valgus (HV), the bunion of the first metatarsophalangeal joint (MTPJ), bothers many adults. No consensus has been reached about the causes of HV, be it a hereditary, or acquired, or multifactorial disease. Nor has agreement been reached using MTPJ angle to assess HV based on X-ray because in most cases the assessment of MTPJ is not reliable as it depends on the posture during scanning. In this study, we assume that HV is predominately acquired and that shoe wearing per se is an important player in HV pathogenesis. To verify our hypothesis, a CT-based finite element (FE) model of the first MTPJ of fossil remains of bear-footed Homo naledi was created and compared to that of five contemporary shoe-wearing wrestlers (10 models from two scans at an interval of about 18 months) because Homo naledi's first MTPJ is an ideal model for non-shoe wearing with parallel sesamoid grooves. We developed the first MTPJ structure transformation method and created MTPJ joint capsule model for both Homo naledi and wrestlers. Constraint on the medial side of the first MTPJ capsule was set to simulate shoe-wearing conditions compared to the lack of medial constraint for barefooted conditions. Analysis of eight FE models of different angles for the first MTPJ of Homo naledi was performed by the first MTPJ transformation method and results showed that stress concentrated on the medial capsule of the first MTPJ in simulated shoe-wearing conditions, even at MTPJ angle of 0°. Increase in the first MTPJ angle further increased stress concentration on the medial side, and stress-growth relationship might reveal the causes of HV. We further developed a method to position the first MTPJ in wrestlers and created CT-based models at two time points. It was evident that the first MTPJ angle increased in all but one athlete, with a maximal increase of 4.03 degrees. This verifies our hypothesis that HV might be developed by wearing shoes. Further longitudinal studies with larger sample sizes are needed to additionally validate our results and determine the magnitude of the effects of shoe wearing on development and progression of HV.
T2  - Frontiers in Bioengineering and Biotechnology
T1  - The Role of Footwear in the Pathogenesis of Hallux Valgus: A Proof-of-Concept Finite Element Analysis in Recent Humans and Homo naledi
VL  - 8
DO  - 10.3389/fbioe.2020.00648
ER  - 

@article{
author = "Yu, Genyu and Fan, Yuzhou and Fan, Yuxuan and Li, Ruining and Liu, Yaming and Antonijević, Đorđe and Milovanović, Petar and Zhang, Bo and Li, Zhiyu and Đurić, Marija and Fan, Yifang",
year = "2020",
abstract = "Hallux valgus (HV), the bunion of the first metatarsophalangeal joint (MTPJ), bothers many adults. No consensus has been reached about the causes of HV, be it a hereditary, or acquired, or multifactorial disease. Nor has agreement been reached using MTPJ angle to assess HV based on X-ray because in most cases the assessment of MTPJ is not reliable as it depends on the posture during scanning. In this study, we assume that HV is predominately acquired and that shoe wearing per se is an important player in HV pathogenesis. To verify our hypothesis, a CT-based finite element (FE) model of the first MTPJ of fossil remains of bear-footed Homo naledi was created and compared to that of five contemporary shoe-wearing wrestlers (10 models from two scans at an interval of about 18 months) because Homo naledi's first MTPJ is an ideal model for non-shoe wearing with parallel sesamoid grooves. We developed the first MTPJ structure transformation method and created MTPJ joint capsule model for both Homo naledi and wrestlers. Constraint on the medial side of the first MTPJ capsule was set to simulate shoe-wearing conditions compared to the lack of medial constraint for barefooted conditions. Analysis of eight FE models of different angles for the first MTPJ of Homo naledi was performed by the first MTPJ transformation method and results showed that stress concentrated on the medial capsule of the first MTPJ in simulated shoe-wearing conditions, even at MTPJ angle of 0°. Increase in the first MTPJ angle further increased stress concentration on the medial side, and stress-growth relationship might reveal the causes of HV. We further developed a method to position the first MTPJ in wrestlers and created CT-based models at two time points. It was evident that the first MTPJ angle increased in all but one athlete, with a maximal increase of 4.03 degrees. This verifies our hypothesis that HV might be developed by wearing shoes. Further longitudinal studies with larger sample sizes are needed to additionally validate our results and determine the magnitude of the effects of shoe wearing on development and progression of HV.",
journal = "Frontiers in Bioengineering and Biotechnology",
title = "The Role of Footwear in the Pathogenesis of Hallux Valgus: A Proof-of-Concept Finite Element Analysis in Recent Humans and Homo naledi",
volume = "8",
doi = "10.3389/fbioe.2020.00648"
}

Yu, G., Fan, Y., Fan, Y., Li, R., Liu, Y., Antonijević, Đ., Milovanović, P., Zhang, B., Li, Z., Đurić, M.,& Fan, Y.. (2020). The Role of Footwear in the Pathogenesis of Hallux Valgus: A Proof-of-Concept Finite Element Analysis in Recent Humans and Homo naledi. in Frontiers in Bioengineering and Biotechnology, 8.
https://doi.org/10.3389/fbioe.2020.00648

Yu G, Fan Y, Fan Y, Li R, Liu Y, Antonijević Đ, Milovanović P, Zhang B, Li Z, Đurić M, Fan Y. The Role of Footwear in the Pathogenesis of Hallux Valgus: A Proof-of-Concept Finite Element Analysis in Recent Humans and Homo naledi. in Frontiers in Bioengineering and Biotechnology. 2020;8.
doi:10.3389/fbioe.2020.00648 .

Yu, Genyu, Fan, Yuzhou, Fan, Yuxuan, Li, Ruining, Liu, Yaming, Antonijević, Đorđe, Milovanović, Petar, Zhang, Bo, Li, Zhiyu, Đurić, Marija, Fan, Yifang, "The Role of Footwear in the Pathogenesis of Hallux Valgus: A Proof-of-Concept Finite Element Analysis in Recent Humans and Homo naledi" in Frontiers in Bioengineering and Biotechnology, 8 (2020),
https://doi.org/10.3389/fbioe.2020.00648 . .

TY  - JOUR
AU  - Ilić, Dragan V.
AU  - Antonijević, Đorđe
AU  - Biočanin, Vladimir
AU  - Čolović, Božana M.
AU  - Danilović, Vesna
AU  - Komlev, Vladimir
AU  - Teterina, Anastasia
AU  - Jokanović, Vukoman R.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8661
AB  - Dental cement materials have been developed with the aim to replace hard dental tissues. The first material used for pulp capping, root canal obturation, bifurcation perforation and apexification is calcium hydroxide (in 1920). A half century later, glass-ionomer cements began to suppress it as dentine substitutes. Finally, in the 1990s, calcium silicate (CS) material appeared in the dental research community as the most promising dentine substitute capable to adequately meet all clinical requirements. The aim of this paper is to present an overview of literature related to studies about CS materials taking into account their physical, chemical and biological properties and clinical applications. This review aims to discuss beneficial and adverse characteristics of CSs concerning interactions to the hard dentine and soft pulp/periodontal tissues. This review article deals with the literature data about currently commercially available CS concerning laboratory and clinical findings. 109 scientific articles were analyzed of which 62 references reported in vitro and 26 in vivo investigations while 21 references comprised reports, reviews and books dealing with both, in vitro and in vivo investigations. Although further data collection is necessary, CSs are promising materials that represent a gold standard for numerous dental clinical procedures. © 2019, Association of Chemists and Chemical Engineers of Serbia. All rights reserved.
T2  - Hemijska industrija
T1  - Physico-chemical and biological properties of dental calcium silicate cements - literature review
VL  - 73
IS  - 5
SP  - 281
EP  - 294
DO  - 10.2298/HEMIND190614027I
ER  - 

@article{
author = "Ilić, Dragan V. and Antonijević, Đorđe and Biočanin, Vladimir and Čolović, Božana M. and Danilović, Vesna and Komlev, Vladimir and Teterina, Anastasia and Jokanović, Vukoman R.",
year = "2019",
abstract = "Dental cement materials have been developed with the aim to replace hard dental tissues. The first material used for pulp capping, root canal obturation, bifurcation perforation and apexification is calcium hydroxide (in 1920). A half century later, glass-ionomer cements began to suppress it as dentine substitutes. Finally, in the 1990s, calcium silicate (CS) material appeared in the dental research community as the most promising dentine substitute capable to adequately meet all clinical requirements. The aim of this paper is to present an overview of literature related to studies about CS materials taking into account their physical, chemical and biological properties and clinical applications. This review aims to discuss beneficial and adverse characteristics of CSs concerning interactions to the hard dentine and soft pulp/periodontal tissues. This review article deals with the literature data about currently commercially available CS concerning laboratory and clinical findings. 109 scientific articles were analyzed of which 62 references reported in vitro and 26 in vivo investigations while 21 references comprised reports, reviews and books dealing with both, in vitro and in vivo investigations. Although further data collection is necessary, CSs are promising materials that represent a gold standard for numerous dental clinical procedures. © 2019, Association of Chemists and Chemical Engineers of Serbia. All rights reserved.",
journal = "Hemijska industrija",
title = "Physico-chemical and biological properties of dental calcium silicate cements - literature review",
volume = "73",
number = "5",
pages = "281-294",
doi = "10.2298/HEMIND190614027I"
}

Ilić, D. V., Antonijević, Đ., Biočanin, V., Čolović, B. M., Danilović, V., Komlev, V., Teterina, A.,& Jokanović, V. R.. (2019). Physico-chemical and biological properties of dental calcium silicate cements - literature review. in Hemijska industrija, 73(5), 281-294.
https://doi.org/10.2298/HEMIND190614027I

Ilić DV, Antonijević Đ, Biočanin V, Čolović BM, Danilović V, Komlev V, Teterina A, Jokanović VR. Physico-chemical and biological properties of dental calcium silicate cements - literature review. in Hemijska industrija. 2019;73(5):281-294.
doi:10.2298/HEMIND190614027I .

Ilić, Dragan V., Antonijević, Đorđe, Biočanin, Vladimir, Čolović, Božana M., Danilović, Vesna, Komlev, Vladimir, Teterina, Anastasia, Jokanović, Vukoman R., "Physico-chemical and biological properties of dental calcium silicate cements - literature review" in Hemijska industrija, 73, no. 5 (2019):281-294,
https://doi.org/10.2298/HEMIND190614027I . .

TY  - JOUR
AU  - Li, Ruining
AU  - Fan, Yuxuan
AU  - Liu, Yaming
AU  - Antonijević, Đorđe
AU  - Li, Zhiyu
AU  - Đurić, Marija
AU  - Fan, Yifang
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8533
AB  - The collection of 1550 Homo naledi fossil remains includes six tarsal and five metatarsal bones from the right foot, forming a nearly complete humanlike flat foot arch. The missing right medial cuneiform, however, raises our interest to explore the true structure of Homo naledi’s foot arch. We hypothesize that Homo naledi does not have flat foot. To verify our hypothesis, the left medial cuneiform of Homo naledi was mirrored using three-dimensional reconstruction and virtual model analysis. Then, we defined quantities of Euler, standardized the body coordinate system of foot bone and developed a new foot arch reconstruction method based on discrete bones. The reconstructed transverse foot arch corroborated our hypothesis, thus providing biomechanical evidence for interpreting the evolution of human locomotion and bringing novel ideas to the research of the biomechanical mechanism of ankle stability. © 2019, Elsevier GmbH. All rights reserved.
T2  - Journal of Comparative Human Biology
T1  - Homo naledi did not have flat foot
VL  - 70
IS  - 2
SP  - 139
EP  - 146
DO  - 10.1127/homo/2019/1059
ER  - 

@article{
author = "Li, Ruining and Fan, Yuxuan and Liu, Yaming and Antonijević, Đorđe and Li, Zhiyu and Đurić, Marija and Fan, Yifang",
year = "2019",
abstract = "The collection of 1550 Homo naledi fossil remains includes six tarsal and five metatarsal bones from the right foot, forming a nearly complete humanlike flat foot arch. The missing right medial cuneiform, however, raises our interest to explore the true structure of Homo naledi’s foot arch. We hypothesize that Homo naledi does not have flat foot. To verify our hypothesis, the left medial cuneiform of Homo naledi was mirrored using three-dimensional reconstruction and virtual model analysis. Then, we defined quantities of Euler, standardized the body coordinate system of foot bone and developed a new foot arch reconstruction method based on discrete bones. The reconstructed transverse foot arch corroborated our hypothesis, thus providing biomechanical evidence for interpreting the evolution of human locomotion and bringing novel ideas to the research of the biomechanical mechanism of ankle stability. © 2019, Elsevier GmbH. All rights reserved.",
journal = "Journal of Comparative Human Biology",
title = "Homo naledi did not have flat foot",
volume = "70",
number = "2",
pages = "139-146",
doi = "10.1127/homo/2019/1059"
}

Li, R., Fan, Y., Liu, Y., Antonijević, Đ., Li, Z., Đurić, M.,& Fan, Y.. (2019). Homo naledi did not have flat foot. in Journal of Comparative Human Biology, 70(2), 139-146.
https://doi.org/10.1127/homo/2019/1059

Li R, Fan Y, Liu Y, Antonijević Đ, Li Z, Đurić M, Fan Y. Homo naledi did not have flat foot. in Journal of Comparative Human Biology. 2019;70(2):139-146.
doi:10.1127/homo/2019/1059 .

Li, Ruining, Fan, Yuxuan, Liu, Yaming, Antonijević, Đorđe, Li, Zhiyu, Đurić, Marija, Fan, Yifang, "Homo naledi did not have flat foot" in Journal of Comparative Human Biology, 70, no. 2 (2019):139-146,
https://doi.org/10.1127/homo/2019/1059 . .

TY  - JOUR
AU  - Fan, Yuxuan
AU  - Antonijević, Đorđe
AU  - Antić, Svetlana
AU  - Li, Ruining
AU  - Liu, Yaming
AU  - Li, Zhiyu
AU  - Đurić, Marija
AU  - Fan, Yifang
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8427
AB  - The aim of the present study was to develop a new method to reconstruct damaged metatarsophalangeal joint (MTPJ) of Homo naledi's fossil and to deepen the understanding of the first metatarsal head (FMH) morphological adaptation in different gait patterns. To this purpose three methods were introduced. The first served to compare the anthropometric linear and volumetric measurements of Homo naledi's MTPJ to that of 10 various athletes. The second was employed to measure curvature diameter in FMH's medial and lateral grooves for sesamoid bones. The third was used to determine the parallelism between medial and lateral FMH grooves. The anthropometric measurements of middle-distance runner to the greatest extent mimicked that of Homo naledi. Thus, it was used to successfully reconstruct the damaged Homo naledi's MTPJ. The highest curvature diameter of medial FMH groove was found in Homo naledi, while in lateral FMH groove it was the highest in volleyball player, suggesting their increased bear loading. The parallelism of medial and lateral FMH grooves was observed only in Homo naledi, while in investigated athletes it was dis-parallel. Athletes' dis-paralleled structures make first MTPJ simple flexion movement a complicated one: not rotating about one axis, but aboutmany, whichmay result in bringing a negative effect on running. In conclusion, the presented method for the reconstruction of the damaged foot bone paves the way for morphological and structural analysis of modern population and fossil hominins' gait pattern. © 2019 Fan, Antonijević, Antic, Li, Liu, Li, Djuric and Fan.
T2  - Frontiers in Bioengineering and Biotechnology
T1  - Reconstructing the First Metatarsophalangeal Joint of Homo naledi
VL  - 7
IS  - JUL
DO  - 10.3389/fbioe.2019.00167
ER  - 

@article{
author = "Fan, Yuxuan and Antonijević, Đorđe and Antić, Svetlana and Li, Ruining and Liu, Yaming and Li, Zhiyu and Đurić, Marija and Fan, Yifang",
year = "2019",
abstract = "The aim of the present study was to develop a new method to reconstruct damaged metatarsophalangeal joint (MTPJ) of Homo naledi's fossil and to deepen the understanding of the first metatarsal head (FMH) morphological adaptation in different gait patterns. To this purpose three methods were introduced. The first served to compare the anthropometric linear and volumetric measurements of Homo naledi's MTPJ to that of 10 various athletes. The second was employed to measure curvature diameter in FMH's medial and lateral grooves for sesamoid bones. The third was used to determine the parallelism between medial and lateral FMH grooves. The anthropometric measurements of middle-distance runner to the greatest extent mimicked that of Homo naledi. Thus, it was used to successfully reconstruct the damaged Homo naledi's MTPJ. The highest curvature diameter of medial FMH groove was found in Homo naledi, while in lateral FMH groove it was the highest in volleyball player, suggesting their increased bear loading. The parallelism of medial and lateral FMH grooves was observed only in Homo naledi, while in investigated athletes it was dis-parallel. Athletes' dis-paralleled structures make first MTPJ simple flexion movement a complicated one: not rotating about one axis, but aboutmany, whichmay result in bringing a negative effect on running. In conclusion, the presented method for the reconstruction of the damaged foot bone paves the way for morphological and structural analysis of modern population and fossil hominins' gait pattern. © 2019 Fan, Antonijević, Antic, Li, Liu, Li, Djuric and Fan.",
journal = "Frontiers in Bioengineering and Biotechnology",
title = "Reconstructing the First Metatarsophalangeal Joint of Homo naledi",
volume = "7",
number = "JUL",
doi = "10.3389/fbioe.2019.00167"
}

Fan, Y., Antonijević, Đ., Antić, S., Li, R., Liu, Y., Li, Z., Đurić, M.,& Fan, Y.. (2019). Reconstructing the First Metatarsophalangeal Joint of Homo naledi. in Frontiers in Bioengineering and Biotechnology, 7(JUL).
https://doi.org/10.3389/fbioe.2019.00167

Fan Y, Antonijević Đ, Antić S, Li R, Liu Y, Li Z, Đurić M, Fan Y. Reconstructing the First Metatarsophalangeal Joint of Homo naledi. in Frontiers in Bioengineering and Biotechnology. 2019;7(JUL).
doi:10.3389/fbioe.2019.00167 .

Fan, Yuxuan, Antonijević, Đorđe, Antić, Svetlana, Li, Ruining, Liu, Yaming, Li, Zhiyu, Đurić, Marija, Fan, Yifang, "Reconstructing the First Metatarsophalangeal Joint of Homo naledi" in Frontiers in Bioengineering and Biotechnology, 7, no. JUL (2019),
https://doi.org/10.3389/fbioe.2019.00167 . .

TY  - JOUR
AU  - Liu, Yaming
AU  - Li, Ruining
AU  - Fan, Yuxuan
AU  - Antonijević, Đorđe
AU  - Milenković, Petar P.
AU  - Li, Zhiyu Y.
AU  - Đurić, Marija
AU  - Fan, Yifang
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7854
AB  - The finite element method is playing an increasingly important role in osteoporosis screening. An accurate bone geometric model, a prerequisite for the finite element analysis, is affected by voxels. Isotropic voxel has advantages in three-dimensional reconstruction, but field of view setting usually results in anisotropic voxels. The main goal of this study was to investigate the influence of anisotropic voxel on the accuracy of three-dimensional reconstruction of bone geometric models. Sixty metatarsal bones were scanned twice with an interval of 18 months with different fields of view. We reconstructed these metatarsals and compared them. The results showed that there was no significant difference in volume, surface, length, width and height and two principal moments of inertia, indicating that anisotropic voxel caused by field of view setting has a neglectable effect on the three-dimensional reconstruction of bone geometric models, and that using finite element method based on bone geometric model reconstructed by anisotropic voxel to predict bone strength is reliable.
T2  - AIP Advances
T1  - The influence of anisotropic voxel caused by field of view setting on the accuracy of three-dimensional reconstruction of bone geometric models
VL  - 8
IS  - 8
SP  - 085111
DO  - 10.1063/1.5041990
ER  - 

@article{
author = "Liu, Yaming and Li, Ruining and Fan, Yuxuan and Antonijević, Đorđe and Milenković, Petar P. and Li, Zhiyu Y. and Đurić, Marija and Fan, Yifang",
year = "2018",
abstract = "The finite element method is playing an increasingly important role in osteoporosis screening. An accurate bone geometric model, a prerequisite for the finite element analysis, is affected by voxels. Isotropic voxel has advantages in three-dimensional reconstruction, but field of view setting usually results in anisotropic voxels. The main goal of this study was to investigate the influence of anisotropic voxel on the accuracy of three-dimensional reconstruction of bone geometric models. Sixty metatarsal bones were scanned twice with an interval of 18 months with different fields of view. We reconstructed these metatarsals and compared them. The results showed that there was no significant difference in volume, surface, length, width and height and two principal moments of inertia, indicating that anisotropic voxel caused by field of view setting has a neglectable effect on the three-dimensional reconstruction of bone geometric models, and that using finite element method based on bone geometric model reconstructed by anisotropic voxel to predict bone strength is reliable.",
journal = "AIP Advances",
title = "The influence of anisotropic voxel caused by field of view setting on the accuracy of three-dimensional reconstruction of bone geometric models",
volume = "8",
number = "8",
pages = "085111",
doi = "10.1063/1.5041990"
}

Liu, Y., Li, R., Fan, Y., Antonijević, Đ., Milenković, P. P., Li, Z. Y., Đurić, M.,& Fan, Y.. (2018). The influence of anisotropic voxel caused by field of view setting on the accuracy of three-dimensional reconstruction of bone geometric models. in AIP Advances, 8(8), 085111.
https://doi.org/10.1063/1.5041990

Liu Y, Li R, Fan Y, Antonijević Đ, Milenković PP, Li ZY, Đurić M, Fan Y. The influence of anisotropic voxel caused by field of view setting on the accuracy of three-dimensional reconstruction of bone geometric models. in AIP Advances. 2018;8(8):085111.
doi:10.1063/1.5041990 .

Liu, Yaming, Li, Ruining, Fan, Yuxuan, Antonijević, Đorđe, Milenković, Petar P., Li, Zhiyu Y., Đurić, Marija, Fan, Yifang, "The influence of anisotropic voxel caused by field of view setting on the accuracy of three-dimensional reconstruction of bone geometric models" in AIP Advances, 8, no. 8 (2018):085111,
https://doi.org/10.1063/1.5041990 . .

TY  - JOUR
AU  - Biočanin, Vladimir
AU  - Antonijević, Đorđe
AU  - Poštić, Srđan D.
AU  - Ilić, Dragan V.
AU  - Vuković, Zorica M.
AU  - Milić, Marija S.
AU  - Fan, Yifang
AU  - Li, Zhiyu Y.
AU  - Brković, Božidar
AU  - Đurić, Marija
PY  - 2018
UR  - http://linkinghub.elsevier.com/retrieve/pii/S0099239917311226
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7740
AB  - Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ({[}10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.
T2  - Journal of Endodontics
T1  - Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin
VL  - 44
IS  - 5
SP  - 816
EP  - 821
DO  - 10.1016/j.joen.2017.09.022
ER  - 

@article{
author = "Biočanin, Vladimir and Antonijević, Đorđe and Poštić, Srđan D. and Ilić, Dragan V. and Vuković, Zorica M. and Milić, Marija S. and Fan, Yifang and Li, Zhiyu Y. and Brković, Božidar and Đurić, Marija",
year = "2018",
abstract = "Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ({[}10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.",
journal = "Journal of Endodontics",
title = "Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin",
volume = "44",
number = "5",
pages = "816-821",
doi = "10.1016/j.joen.2017.09.022"
}

Biočanin, V., Antonijević, Đ., Poštić, S. D., Ilić, D. V., Vuković, Z. M., Milić, M. S., Fan, Y., Li, Z. Y., Brković, B.,& Đurić, M.. (2018). Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin. in Journal of Endodontics, 44(5), 816-821.
https://doi.org/10.1016/j.joen.2017.09.022

Biočanin V, Antonijević Đ, Poštić SD, Ilić DV, Vuković ZM, Milić MS, Fan Y, Li ZY, Brković B, Đurić M. Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin. in Journal of Endodontics. 2018;44(5):816-821.
doi:10.1016/j.joen.2017.09.022 .

Biočanin, Vladimir, Antonijević, Đorđe, Poštić, Srđan D., Ilić, Dragan V., Vuković, Zorica M., Milić, Marija S., Fan, Yifang, Li, Zhiyu Y., Brković, Božidar, Đurić, Marija, "Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin" in Journal of Endodontics, 44, no. 5 (2018):816-821,
https://doi.org/10.1016/j.joen.2017.09.022 . .

TY  - JOUR
AU  - Ćetković, Dejan
AU  - Antić, Svetlana
AU  - Antonijević, Đorđe
AU  - Brković, Božidar
AU  - Đukić, Ksenija M.
AU  - Vujašković, Goran
AU  - Đurić, Marija
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7999
AB  - Background. The authors investigated morphologic parameters of the palatal cortex that affect the diffusion of local anesthetic solution in the region of the anterior middle superior alveolar (AMSA) nerve block injection site.   Methods. The authors used computed tomographic (CT) and micro-CT imaging to assess 20 human skulls from an anatomic collection. Analysis of the C1 images included frequency, distribution, and width of the nutrient canals in the bony palate, according to to the person's sex and age. Micro-CT analysis involved measuring the thickness and porosity of palatal cortical bone in the area of the AMSA injection site in relation to the thickness and porosity of the opposite buccal cortical bone.   Results. There was a statistically significant difference (P = .042) in the location of the nutrient canals between male specimens (> 50% in the border region) and female specimens (> 50% in the palatal process). Furthermore, the female skulls had significantly wider nutrient canal foramina (P = .042) than did the male skulls. Despite greater thickness, the palatal cortex in the area of the AMSA injection site had slightly greater porosity than did the buccal cortex. A significantly greater number of microcanals penetrated the whole cortical thickness in palatal than in buccal cortical bone (P = .001).   Conclusions. The distribution and width of nutrient canals differed between male and female skulls. At the microscopic level, structural characteristics of the palatal cortex provide a good anatomic basis for the potential of a satisfactory AMSA injection success rate.   Practical Implications. The AMSA technique success rate might be increased if the clinician adjusts the injection site to the distribution of nutrient canals, depending on the sex of the patient.
T2  - The Journal of the American Dental Association
T1  - Nutrient canals and porosity of the bony palate: A basis for the biological plausibility of the anterior middle superior alveolar nerve block
VL  - 149
IS  - 10
SP  - 859
EP  - 868
DO  - 10.1016/j.adaj.2018.05.015
ER  - 

@article{
author = "Ćetković, Dejan and Antić, Svetlana and Antonijević, Đorđe and Brković, Božidar and Đukić, Ksenija M. and Vujašković, Goran and Đurić, Marija",
year = "2018",
abstract = "Background. The authors investigated morphologic parameters of the palatal cortex that affect the diffusion of local anesthetic solution in the region of the anterior middle superior alveolar (AMSA) nerve block injection site.   Methods. The authors used computed tomographic (CT) and micro-CT imaging to assess 20 human skulls from an anatomic collection. Analysis of the C1 images included frequency, distribution, and width of the nutrient canals in the bony palate, according to to the person's sex and age. Micro-CT analysis involved measuring the thickness and porosity of palatal cortical bone in the area of the AMSA injection site in relation to the thickness and porosity of the opposite buccal cortical bone.   Results. There was a statistically significant difference (P = .042) in the location of the nutrient canals between male specimens (> 50% in the border region) and female specimens (> 50% in the palatal process). Furthermore, the female skulls had significantly wider nutrient canal foramina (P = .042) than did the male skulls. Despite greater thickness, the palatal cortex in the area of the AMSA injection site had slightly greater porosity than did the buccal cortex. A significantly greater number of microcanals penetrated the whole cortical thickness in palatal than in buccal cortical bone (P = .001).   Conclusions. The distribution and width of nutrient canals differed between male and female skulls. At the microscopic level, structural characteristics of the palatal cortex provide a good anatomic basis for the potential of a satisfactory AMSA injection success rate.   Practical Implications. The AMSA technique success rate might be increased if the clinician adjusts the injection site to the distribution of nutrient canals, depending on the sex of the patient.",
journal = "The Journal of the American Dental Association",
title = "Nutrient canals and porosity of the bony palate: A basis for the biological plausibility of the anterior middle superior alveolar nerve block",
volume = "149",
number = "10",
pages = "859-868",
doi = "10.1016/j.adaj.2018.05.015"
}

Ćetković, D., Antić, S., Antonijević, Đ., Brković, B., Đukić, K. M., Vujašković, G.,& Đurić, M.. (2018). Nutrient canals and porosity of the bony palate: A basis for the biological plausibility of the anterior middle superior alveolar nerve block. in The Journal of the American Dental Association, 149(10), 859-868.
https://doi.org/10.1016/j.adaj.2018.05.015

Ćetković D, Antić S, Antonijević Đ, Brković B, Đukić KM, Vujašković G, Đurić M. Nutrient canals and porosity of the bony palate: A basis for the biological plausibility of the anterior middle superior alveolar nerve block. in The Journal of the American Dental Association. 2018;149(10):859-868.
doi:10.1016/j.adaj.2018.05.015 .

Ćetković, Dejan, Antić, Svetlana, Antonijević, Đorđe, Brković, Božidar, Đukić, Ksenija M., Vujašković, Goran, Đurić, Marija, "Nutrient canals and porosity of the bony palate: A basis for the biological plausibility of the anterior middle superior alveolar nerve block" in The Journal of the American Dental Association, 149, no. 10 (2018):859-868,
https://doi.org/10.1016/j.adaj.2018.05.015 . .

TY  - JOUR
AU  - Jokanović, Vukoman R.
AU  - Čolović, Božana M.
AU  - Marković, Dejan
AU  - Petrović, Milan
AU  - Soldatovic, Ivan
AU  - Antonijević, Đorđe
AU  - Milosavljević, Petar
AU  - Sjerobabin, Nikola
AU  - Sopta, Jelena
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1604
AB  - This study examined the potential of a new porous calcium hydroxyapatite scaffold covered with poly (lactide-co-glycolide) (PLGA) as a bone substitute, identifying its advantages over Geistlich Bio-Oss (R), considered the gold standard, in in vivo biofunctionality investigations. Structural and morphological properties of the new scaffold were analyzed by scanning electron and atomic force microscopy. The biofunctionality assays were performed on New Zealand white rabbits using new scaffold for filling full-thickness defects of critical size. The evaluated parameters were: the presence of macrophages, giant cells, monoocytes, plasma cells, granulocytes, neo-angiogenesis, fibroplasia, and the percentage of mineralization. Parallel biofunctionality assays were performed using Geistlich Bio-Oss (R). The appearance of bone defects 12 weeks after the new scaffold implantation showed the presence of a small number of typical immune response cells. Furthermore, significantly reduced number of capillary buds, low intensity of fibroplasia and high degree of mineralization in a lamellar pattern indicated that the inflammation process has been almost completely overcome and that the new bone formed was in the final phase of remodeling. All biofunctionality assays proved the new scaffolds suitability as a bone substitute for applications in maxillofacial surgery. It showed numerous biological advantages over Geistlich Bio-Oss (R) which was reflected mainly as a lower number of giant cells surrounding implanted material and higher degree of mineralization in new formed bone.
T2  - Biomedical Engineering / Biomedizinische Technik
T1  - Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation
VL  - 62
IS  - 3
SP  - 295
EP  - 306
DO  - 10.1515/bmt-2015-0164
ER  - 

@article{
author = "Jokanović, Vukoman R. and Čolović, Božana M. and Marković, Dejan and Petrović, Milan and Soldatovic, Ivan and Antonijević, Đorđe and Milosavljević, Petar and Sjerobabin, Nikola and Sopta, Jelena",
year = "2017",
abstract = "This study examined the potential of a new porous calcium hydroxyapatite scaffold covered with poly (lactide-co-glycolide) (PLGA) as a bone substitute, identifying its advantages over Geistlich Bio-Oss (R), considered the gold standard, in in vivo biofunctionality investigations. Structural and morphological properties of the new scaffold were analyzed by scanning electron and atomic force microscopy. The biofunctionality assays were performed on New Zealand white rabbits using new scaffold for filling full-thickness defects of critical size. The evaluated parameters were: the presence of macrophages, giant cells, monoocytes, plasma cells, granulocytes, neo-angiogenesis, fibroplasia, and the percentage of mineralization. Parallel biofunctionality assays were performed using Geistlich Bio-Oss (R). The appearance of bone defects 12 weeks after the new scaffold implantation showed the presence of a small number of typical immune response cells. Furthermore, significantly reduced number of capillary buds, low intensity of fibroplasia and high degree of mineralization in a lamellar pattern indicated that the inflammation process has been almost completely overcome and that the new bone formed was in the final phase of remodeling. All biofunctionality assays proved the new scaffolds suitability as a bone substitute for applications in maxillofacial surgery. It showed numerous biological advantages over Geistlich Bio-Oss (R) which was reflected mainly as a lower number of giant cells surrounding implanted material and higher degree of mineralization in new formed bone.",
journal = "Biomedical Engineering / Biomedizinische Technik",
title = "Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation",
volume = "62",
number = "3",
pages = "295-306",
doi = "10.1515/bmt-2015-0164"
}

Jokanović, V. R., Čolović, B. M., Marković, D., Petrović, M., Soldatovic, I., Antonijević, Đ., Milosavljević, P., Sjerobabin, N.,& Sopta, J.. (2017). Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation. in Biomedical Engineering / Biomedizinische Technik, 62(3), 295-306.
https://doi.org/10.1515/bmt-2015-0164

Jokanović VR, Čolović BM, Marković D, Petrović M, Soldatovic I, Antonijević Đ, Milosavljević P, Sjerobabin N, Sopta J. Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation. in Biomedical Engineering / Biomedizinische Technik. 2017;62(3):295-306.
doi:10.1515/bmt-2015-0164 .

Jokanović, Vukoman R., Čolović, Božana M., Marković, Dejan, Petrović, Milan, Soldatovic, Ivan, Antonijević, Đorđe, Milosavljević, Petar, Sjerobabin, Nikola, Sopta, Jelena, "Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation" in Biomedical Engineering / Biomedizinische Technik, 62, no. 3 (2017):295-306,
https://doi.org/10.1515/bmt-2015-0164 . .

TY  - JOUR
AU  - Antonijević, Đorđe
AU  - Jesthke, Anke
AU  - Čolović, Božana M.
AU  - Milovanović, Petar
AU  - Jevremovic, Danimir
AU  - Kisić, Danilo
AU  - vom Scheidt, Annika
AU  - Hahn, Michael
AU  - Amling, Michael
AU  - Jokanović, Vukoman R.
AU  - Busse, Bjoern
AU  - Đurić, Marija
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/847
AB  - Introduction: Calcium silicate cements (CSCs) with the addition of nanohydroxyapatite and calcium carbonate play a critical role in dental applications. To further improve their properties, particularly radiopacity and biointeractivity, the fluoride-containing radiopacifier ytterbium trifluoride (YbF3) was added to their composition, and biological and mechanical characteristics were evaluated. Methods: YbF3 was added to 3 different CSCs: cement I (CSC + calcium carbonate), cement II (CSC + nanohydroxyapatite), and Portland cement. Material characterization encompassed measurements of pH, calcium, ytterbium, and fluoride ion release; radiopacity; setting time; porosity; microindentation properties; wettability; and Fourier transform infrared spectroscopic, x-ray diffraction, and scanning electron microscopic analyses. Osteoblast- and osteoclast-like cells were grown on the materials surface to evaluate their adherence. Results: The addition of calcium carbonate, nanohydroxyapatite, and 30 wt% of YbF3 improved radiopacity and the setting time of experimental cements. The pH values did not differ among the groups. The greatest ytterbium and fluoride releases occurred in the Portland cement + YbF3 group. Combined x-ray diffraction and Fourier transform infrared spectroscopic analysis showed the presence of calcium hydroxide and calcium silicate hydrates. In addition, the presence of calcium ytterbium fluoride and ytterbium oxide proved that YbF3 reacted with cement compounds. Wettability of cement I + YbF3 was superior to other formulations, but its porosity and microindentation properties were weaker than in the Portland cement + YbF3 mixture. Cement II + YbF3 presented micromechanical indentation and porosity characteristics similar to the Portland-based cement formulation. Osteoclast- and osteoblast-like cells adhered to the cements surfaces without alteration of the cell structural integrity. Conclusions: YbF3-containing CSCs with nanostructured hydroxyapatite and calcium carbonate are well suited for dental application.
T2  - Journal of Endodontics
T1  - Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements
VL  - 41
IS  - 12
SP  - 2050
EP  - 2057
DO  - 10.1016/j.joen.2015.09.008
ER  - 

@article{
author = "Antonijević, Đorđe and Jesthke, Anke and Čolović, Božana M. and Milovanović, Petar and Jevremovic, Danimir and Kisić, Danilo and vom Scheidt, Annika and Hahn, Michael and Amling, Michael and Jokanović, Vukoman R. and Busse, Bjoern and Đurić, Marija",
year = "2015",
abstract = "Introduction: Calcium silicate cements (CSCs) with the addition of nanohydroxyapatite and calcium carbonate play a critical role in dental applications. To further improve their properties, particularly radiopacity and biointeractivity, the fluoride-containing radiopacifier ytterbium trifluoride (YbF3) was added to their composition, and biological and mechanical characteristics were evaluated. Methods: YbF3 was added to 3 different CSCs: cement I (CSC + calcium carbonate), cement II (CSC + nanohydroxyapatite), and Portland cement. Material characterization encompassed measurements of pH, calcium, ytterbium, and fluoride ion release; radiopacity; setting time; porosity; microindentation properties; wettability; and Fourier transform infrared spectroscopic, x-ray diffraction, and scanning electron microscopic analyses. Osteoblast- and osteoclast-like cells were grown on the materials surface to evaluate their adherence. Results: The addition of calcium carbonate, nanohydroxyapatite, and 30 wt% of YbF3 improved radiopacity and the setting time of experimental cements. The pH values did not differ among the groups. The greatest ytterbium and fluoride releases occurred in the Portland cement + YbF3 group. Combined x-ray diffraction and Fourier transform infrared spectroscopic analysis showed the presence of calcium hydroxide and calcium silicate hydrates. In addition, the presence of calcium ytterbium fluoride and ytterbium oxide proved that YbF3 reacted with cement compounds. Wettability of cement I + YbF3 was superior to other formulations, but its porosity and microindentation properties were weaker than in the Portland cement + YbF3 mixture. Cement II + YbF3 presented micromechanical indentation and porosity characteristics similar to the Portland-based cement formulation. Osteoclast- and osteoblast-like cells adhered to the cements surfaces without alteration of the cell structural integrity. Conclusions: YbF3-containing CSCs with nanostructured hydroxyapatite and calcium carbonate are well suited for dental application.",
journal = "Journal of Endodontics",
title = "Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements",
volume = "41",
number = "12",
pages = "2050-2057",
doi = "10.1016/j.joen.2015.09.008"
}

Antonijević, Đ., Jesthke, A., Čolović, B. M., Milovanović, P., Jevremovic, D., Kisić, D., vom Scheidt, A., Hahn, M., Amling, M., Jokanović, V. R., Busse, B.,& Đurić, M.. (2015). Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements. in Journal of Endodontics, 41(12), 2050-2057.
https://doi.org/10.1016/j.joen.2015.09.008

Antonijević Đ, Jesthke A, Čolović BM, Milovanović P, Jevremovic D, Kisić D, vom Scheidt A, Hahn M, Amling M, Jokanović VR, Busse B, Đurić M. Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements. in Journal of Endodontics. 2015;41(12):2050-2057.
doi:10.1016/j.joen.2015.09.008 .

Antonijević, Đorđe, Jesthke, Anke, Čolović, Božana M., Milovanović, Petar, Jevremovic, Danimir, Kisić, Danilo, vom Scheidt, Annika, Hahn, Michael, Amling, Michael, Jokanović, Vukoman R., Busse, Bjoern, Đurić, Marija, "Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements" in Journal of Endodontics, 41, no. 12 (2015):2050-2057,
https://doi.org/10.1016/j.joen.2015.09.008 . .

TY  - JOUR
AU  - Antonijević, Đorđe
AU  - Milovanović, Petar
AU  - Brajkovic, Denis
AU  - Ilić, Dragan V.
AU  - Hahn, Michael
AU  - Amling, Michael
AU  - Rakočević, Zlatko Lj.
AU  - Đurić, Marija
AU  - Busse, Bjoern
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/791
AB  - The objective of this study was to determine the effects of various irrigation solutions on root canal dentine and gutta-percha surface properties. In addition, the effects of disinfectant chemicals on the wettability and surface morphological properties of the filling materials were evaluated. Ethylenediaminetetraacetic acid (EDTA), citric acid, and ozone were employed as irrigation solutions for dentine and gutta-percha treatment. Thereafter, the samples microstructure, degree of mineralization, and mechanical properties were assessed by means of quantitative backscattered electron imaging (qBEI) and reference point indentation (RN). A contact angle analyzer was used to measure adhesion on the tested materials. Here, EDTA had the most significant affect on both the mechanical properties and the adhesive behavior of dentine. Citric acid did not affect dentine wettability, whereas the indentation properties and the mineralization were reduced. Similar effects were observed when ozone was used. The dentinal tubules were significantly widened in citric acid compared to the ozone group. EDTA causes considerable micromechanical surface alteration of dentine and gutta-percha, but represents the best option in clinical cases where a high adhesiveness of the filling materials is desired. (c) 2015 Elsevier B.V. All rights reserved.
T2  - Applied Surface Science
T1  - Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation
VL  - 355
SP  - 369
EP  - 378
DO  - 10.1016/j.apsusc.2015.07.023
ER  - 

@article{
author = "Antonijević, Đorđe and Milovanović, Petar and Brajkovic, Denis and Ilić, Dragan V. and Hahn, Michael and Amling, Michael and Rakočević, Zlatko Lj. and Đurić, Marija and Busse, Bjoern",
year = "2015",
abstract = "The objective of this study was to determine the effects of various irrigation solutions on root canal dentine and gutta-percha surface properties. In addition, the effects of disinfectant chemicals on the wettability and surface morphological properties of the filling materials were evaluated. Ethylenediaminetetraacetic acid (EDTA), citric acid, and ozone were employed as irrigation solutions for dentine and gutta-percha treatment. Thereafter, the samples microstructure, degree of mineralization, and mechanical properties were assessed by means of quantitative backscattered electron imaging (qBEI) and reference point indentation (RN). A contact angle analyzer was used to measure adhesion on the tested materials. Here, EDTA had the most significant affect on both the mechanical properties and the adhesive behavior of dentine. Citric acid did not affect dentine wettability, whereas the indentation properties and the mineralization were reduced. Similar effects were observed when ozone was used. The dentinal tubules were significantly widened in citric acid compared to the ozone group. EDTA causes considerable micromechanical surface alteration of dentine and gutta-percha, but represents the best option in clinical cases where a high adhesiveness of the filling materials is desired. (c) 2015 Elsevier B.V. All rights reserved.",
journal = "Applied Surface Science",
title = "Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation",
volume = "355",
pages = "369-378",
doi = "10.1016/j.apsusc.2015.07.023"
}

Antonijević, Đ., Milovanović, P., Brajkovic, D., Ilić, D. V., Hahn, M., Amling, M., Rakočević, Z. Lj., Đurić, M.,& Busse, B.. (2015). Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation. in Applied Surface Science, 355, 369-378.
https://doi.org/10.1016/j.apsusc.2015.07.023

Antonijević Đ, Milovanović P, Brajkovic D, Ilić DV, Hahn M, Amling M, Rakočević ZL, Đurić M, Busse B. Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation. in Applied Surface Science. 2015;355:369-378.
doi:10.1016/j.apsusc.2015.07.023 .

Antonijević, Đorđe, Milovanović, Petar, Brajkovic, Denis, Ilić, Dragan V., Hahn, Michael, Amling, Michael, Rakočević, Zlatko Lj., Đurić, Marija, Busse, Bjoern, "Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation" in Applied Surface Science, 355 (2015):369-378,
https://doi.org/10.1016/j.apsusc.2015.07.023 . .

TY  - JOUR
AU  - Brajkovic, Denis
AU  - Antonijević, Đorđe
AU  - Milovanović, Petar
AU  - Kisić, Danilo
AU  - Zelic, Ksenija
AU  - Đurić, Marija
AU  - Rakočević, Zlatko Lj.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6071
AB  - Background: Material surface free energy and surface roughness strongly influence the bacterial adhesion in oral cavity. The aim of this study was to analyze these two parameters in various commercial luting agents used for cementation of implant restorations. Materials and methods: Zinc-based, glass-ionomers, resin modified glass-ionomer and resin-cements were investigated. Contact angle and surface free energy were measured by contact angle analyzer using Image J software program. Materials average roughness and fractal dimension were calculated based on Atomic Force Microscope topography images. Results: Zinc phosphate cements presented significantly higher total surface free energy and significantly lower dispersive component of surface free energy compared to other groups, while resin-cements showed significantly lower polar component than other groups. The surface roughness and fractal dimension values were statistically the highest in the zinc phosphate cements and the lowest for the glass-ionomers cements. Conclusion: Glass-ionomers-cements presented lower values of surface free energy and surface roughness than zinc phosphate and resin cements, indicating that their surfaces are less prone to biofilm adhesion. Practical implications: Within limitations of an in vitro trial, our results indicate that glass-ionomers-cements could be the cements of choice for fixation of cement retained implant restorations due to superior surface properties compared to zinc phosphate and resin cements, which may result in reduced plaque formation and presumably prevent periimplant infection. (C) 2014 Elsevier B.V. All rights reserved.
T2  - Applied Surface Science
T1  - Surface characterization of the cement for retention of implant supported dental prostheses: In vitro evaluation of cement roughness and surface free energy
VL  - 311
SP  - 131
EP  - 138
DO  - 10.1016/j.apsusc.2014.05.027
ER  - 

@article{
author = "Brajkovic, Denis and Antonijević, Đorđe and Milovanović, Petar and Kisić, Danilo and Zelic, Ksenija and Đurić, Marija and Rakočević, Zlatko Lj.",
year = "2014",
abstract = "Background: Material surface free energy and surface roughness strongly influence the bacterial adhesion in oral cavity. The aim of this study was to analyze these two parameters in various commercial luting agents used for cementation of implant restorations. Materials and methods: Zinc-based, glass-ionomers, resin modified glass-ionomer and resin-cements were investigated. Contact angle and surface free energy were measured by contact angle analyzer using Image J software program. Materials average roughness and fractal dimension were calculated based on Atomic Force Microscope topography images. Results: Zinc phosphate cements presented significantly higher total surface free energy and significantly lower dispersive component of surface free energy compared to other groups, while resin-cements showed significantly lower polar component than other groups. The surface roughness and fractal dimension values were statistically the highest in the zinc phosphate cements and the lowest for the glass-ionomers cements. Conclusion: Glass-ionomers-cements presented lower values of surface free energy and surface roughness than zinc phosphate and resin cements, indicating that their surfaces are less prone to biofilm adhesion. Practical implications: Within limitations of an in vitro trial, our results indicate that glass-ionomers-cements could be the cements of choice for fixation of cement retained implant restorations due to superior surface properties compared to zinc phosphate and resin cements, which may result in reduced plaque formation and presumably prevent periimplant infection. (C) 2014 Elsevier B.V. All rights reserved.",
journal = "Applied Surface Science",
title = "Surface characterization of the cement for retention of implant supported dental prostheses: In vitro evaluation of cement roughness and surface free energy",
volume = "311",
pages = "131-138",
doi = "10.1016/j.apsusc.2014.05.027"
}

Brajkovic, D., Antonijević, Đ., Milovanović, P., Kisić, D., Zelic, K., Đurić, M.,& Rakočević, Z. Lj.. (2014). Surface characterization of the cement for retention of implant supported dental prostheses: In vitro evaluation of cement roughness and surface free energy. in Applied Surface Science, 311, 131-138.
https://doi.org/10.1016/j.apsusc.2014.05.027

Brajkovic D, Antonijević Đ, Milovanović P, Kisić D, Zelic K, Đurić M, Rakočević ZL. Surface characterization of the cement for retention of implant supported dental prostheses: In vitro evaluation of cement roughness and surface free energy. in Applied Surface Science. 2014;311:131-138.
doi:10.1016/j.apsusc.2014.05.027 .

Brajkovic, Denis, Antonijević, Đorđe, Milovanović, Petar, Kisić, Danilo, Zelic, Ksenija, Đurić, Marija, Rakočević, Zlatko Lj., "Surface characterization of the cement for retention of implant supported dental prostheses: In vitro evaluation of cement roughness and surface free energy" in Applied Surface Science, 311 (2014):131-138,
https://doi.org/10.1016/j.apsusc.2014.05.027 . .

TY  - JOUR
AU  - Antonijević, Đorđe
AU  - Denis, Brajkovic
AU  - Nenadović, Miloš
AU  - Milovanović, Petar
AU  - Marija, Djuric
AU  - Rakočević, Zlatko Lj.
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5637
AB  - Objective: The aim of this in vitro study was to compare the surface roughness parameters of four different types of dental luting agents used for cementation of implant restorations. Method and materials: Five specimens (8 mm high and 1 mm thick) of each cement were made using metal ring steelless molds. Atomic Force Microscope was employed to analyze different surface texture parameters of the materials. Bearing ratio analysis was used to calculate the potential microgap size between the cement and implant material and to calculate the depth of the valleys on the cement surface, while power spectral density (PSD) measurements were performed to measure the percentage of the surface prone to bacterial adhesion. Results: Glass ionomer cement showed significantly lower value of average surface roughness then the other groups of the materials (P LT 0.05) which was in line with the results of Bearing ratio analysis. On the other side, PSD analysis showed that zinc phosphate cement experience the lowest percentage of the surface which promote bacterial colonization. Conclusion: Glas ionomer cements present the surface roughness parameters that are less favorable for bacterial adhesion than that of zinc phosphate, resin-modified glass ionomer and resin cements. Microsc. Res. Tech. 76:924-930, 2013. (c) 2013 Wiley Periodicals, Inc.
T2  - Microscopy Research and Technique
T1  - An in vitro atomic force microscopic study of commercially available dental luting materials
VL  - 76
IS  - 9
SP  - 924
EP  - 930
DO  - 10.1002/jemt.22249
ER  - 

@article{
author = "Antonijević, Đorđe and Denis, Brajkovic and Nenadović, Miloš and Milovanović, Petar and Marija, Djuric and Rakočević, Zlatko Lj.",
year = "2013",
abstract = "Objective: The aim of this in vitro study was to compare the surface roughness parameters of four different types of dental luting agents used for cementation of implant restorations. Method and materials: Five specimens (8 mm high and 1 mm thick) of each cement were made using metal ring steelless molds. Atomic Force Microscope was employed to analyze different surface texture parameters of the materials. Bearing ratio analysis was used to calculate the potential microgap size between the cement and implant material and to calculate the depth of the valleys on the cement surface, while power spectral density (PSD) measurements were performed to measure the percentage of the surface prone to bacterial adhesion. Results: Glass ionomer cement showed significantly lower value of average surface roughness then the other groups of the materials (P LT 0.05) which was in line with the results of Bearing ratio analysis. On the other side, PSD analysis showed that zinc phosphate cement experience the lowest percentage of the surface which promote bacterial colonization. Conclusion: Glas ionomer cements present the surface roughness parameters that are less favorable for bacterial adhesion than that of zinc phosphate, resin-modified glass ionomer and resin cements. Microsc. Res. Tech. 76:924-930, 2013. (c) 2013 Wiley Periodicals, Inc.",
journal = "Microscopy Research and Technique",
title = "An in vitro atomic force microscopic study of commercially available dental luting materials",
volume = "76",
number = "9",
pages = "924-930",
doi = "10.1002/jemt.22249"
}

Antonijević, Đ., Denis, B., Nenadović, M., Milovanović, P., Marija, D.,& Rakočević, Z. Lj.. (2013). An in vitro atomic force microscopic study of commercially available dental luting materials. in Microscopy Research and Technique, 76(9), 924-930.
https://doi.org/10.1002/jemt.22249

Antonijević Đ, Denis B, Nenadović M, Milovanović P, Marija D, Rakočević ZL. An in vitro atomic force microscopic study of commercially available dental luting materials. in Microscopy Research and Technique. 2013;76(9):924-930.
doi:10.1002/jemt.22249 .

Antonijević, Đorđe, Denis, Brajkovic, Nenadović, Miloš, Milovanović, Petar, Marija, Djuric, Rakočević, Zlatko Lj., "An in vitro atomic force microscopic study of commercially available dental luting materials" in Microscopy Research and Technique, 76, no. 9 (2013):924-930,
https://doi.org/10.1002/jemt.22249 . .