TY  - JOUR
AU  - Hollo, B. Barta
AU  - Magyari, J.
AU  - Armaković, Sanja J.
AU  - Bogdanović, Goran A.
AU  - Rodic, M. V.
AU  - Armaković, Sanja J.
AU  - Molnar, J.
AU  - Spengler, G.
AU  - Leovac, Vukadin M.
AU  - Szecsenyi, K. Meszaros
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7115
AB  - A new hydrazone-type ligand with a five N-donor set and its coordination compounds with Co(III), Ni(II), Cu(II) and Zn(II) metal centres were synthesized. The crystal and molecular structure of the Co(III) complex was determined by X-ray structural analysis. All the compounds were characterized by elemental analysis, molar conductivity and FT-IR spectral data. The cobalt(III) compound is a neutral binuclear complex formed by coordination of two, doubly deprotonated ligand anions as bridges between the Co(III) centres. The metal centres are additionally connected by a peroxido bridge, which was observed for the first time in Co(III) complexes with similar ligands. The other coordination compounds are mononuclear complexes wherein only one doubly deprotonated ligand is coordinated to the central ion in a tetradentate fashion. The structures were theoretically investigated employing density functional theory (DFT) calculations with B3LYP exchange-correlation functional and LACV3P+(d,p) basis sets for the coordination compounds and 6-31+G(d,p) basis set for the ligand. Molecular electrostatic potential (MEP) and average local ionization energy (ALIE) surfaces were calculated to study the reactive properties of the compounds. The thermal behaviour of the compounds was determined by simultaneous thermogravimetric-differential scanning calorimetric (TG-DSC) measurements and the results were correlated to the proposed structures and to calculated MEP/ALIE surfaces. The compounds were tested in vitro for antiproliferative effects on parental (L5178Y) mouse T-cell lymphoma cells, on L5178Y transfected with pHa ABCB1/A retrovirus and for reversal of multidrug resistance (MDR) in tumor cells by flow cytometry. The preliminary measurements showed that the cobalt(III) compound was an effective inhibitor of the ABC transporter PGP drug efflux pump. The ligand was somewhat less effective, the zinc complex had a moderate inhibition activity, whereas the nickel(II) and copper(II) compounds were inactive.
T2  - New Journal of Chemistry
T1  - Coordination compounds of a hydrazone derivative with Co(III), Ni(II), Cu(II) and Zn(II): synthesis, characterization, reactivity assessment and biological evaluation
VL  - 40
IS  - 7
SP  - 5885
EP  - 5895
DO  - 10.1039/c6nj00560h
ER  - 

@article{
author = "Hollo, B. Barta and Magyari, J. and Armaković, Sanja J. and Bogdanović, Goran A. and Rodic, M. V. and Armaković, Sanja J. and Molnar, J. and Spengler, G. and Leovac, Vukadin M. and Szecsenyi, K. Meszaros",
year = "2016",
abstract = "A new hydrazone-type ligand with a five N-donor set and its coordination compounds with Co(III), Ni(II), Cu(II) and Zn(II) metal centres were synthesized. The crystal and molecular structure of the Co(III) complex was determined by X-ray structural analysis. All the compounds were characterized by elemental analysis, molar conductivity and FT-IR spectral data. The cobalt(III) compound is a neutral binuclear complex formed by coordination of two, doubly deprotonated ligand anions as bridges between the Co(III) centres. The metal centres are additionally connected by a peroxido bridge, which was observed for the first time in Co(III) complexes with similar ligands. The other coordination compounds are mononuclear complexes wherein only one doubly deprotonated ligand is coordinated to the central ion in a tetradentate fashion. The structures were theoretically investigated employing density functional theory (DFT) calculations with B3LYP exchange-correlation functional and LACV3P+(d,p) basis sets for the coordination compounds and 6-31+G(d,p) basis set for the ligand. Molecular electrostatic potential (MEP) and average local ionization energy (ALIE) surfaces were calculated to study the reactive properties of the compounds. The thermal behaviour of the compounds was determined by simultaneous thermogravimetric-differential scanning calorimetric (TG-DSC) measurements and the results were correlated to the proposed structures and to calculated MEP/ALIE surfaces. The compounds were tested in vitro for antiproliferative effects on parental (L5178Y) mouse T-cell lymphoma cells, on L5178Y transfected with pHa ABCB1/A retrovirus and for reversal of multidrug resistance (MDR) in tumor cells by flow cytometry. The preliminary measurements showed that the cobalt(III) compound was an effective inhibitor of the ABC transporter PGP drug efflux pump. The ligand was somewhat less effective, the zinc complex had a moderate inhibition activity, whereas the nickel(II) and copper(II) compounds were inactive.",
journal = "New Journal of Chemistry",
title = "Coordination compounds of a hydrazone derivative with Co(III), Ni(II), Cu(II) and Zn(II): synthesis, characterization, reactivity assessment and biological evaluation",
volume = "40",
number = "7",
pages = "5885-5895",
doi = "10.1039/c6nj00560h"
}

Hollo, B. B., Magyari, J., Armaković, S. J., Bogdanović, G. A., Rodic, M. V., Armaković, S. J., Molnar, J., Spengler, G., Leovac, V. M.,& Szecsenyi, K. M.. (2016). Coordination compounds of a hydrazone derivative with Co(III), Ni(II), Cu(II) and Zn(II): synthesis, characterization, reactivity assessment and biological evaluation. in New Journal of Chemistry, 40(7), 5885-5895.
https://doi.org/10.1039/c6nj00560h

Hollo BB, Magyari J, Armaković SJ, Bogdanović GA, Rodic MV, Armaković SJ, Molnar J, Spengler G, Leovac VM, Szecsenyi KM. Coordination compounds of a hydrazone derivative with Co(III), Ni(II), Cu(II) and Zn(II): synthesis, characterization, reactivity assessment and biological evaluation. in New Journal of Chemistry. 2016;40(7):5885-5895.
doi:10.1039/c6nj00560h .

Hollo, B. Barta, Magyari, J., Armaković, Sanja J., Bogdanović, Goran A., Rodic, M. V., Armaković, Sanja J., Molnar, J., Spengler, G., Leovac, Vukadin M., Szecsenyi, K. Meszaros, "Coordination compounds of a hydrazone derivative with Co(III), Ni(II), Cu(II) and Zn(II): synthesis, characterization, reactivity assessment and biological evaluation" in New Journal of Chemistry, 40, no. 7 (2016):5885-5895,
https://doi.org/10.1039/c6nj00560h . .

TY  - JOUR
AU  - Vujačić, Ana V.
AU  - Savić, Jasmina
AU  - Sovilj, Sofija P.
AU  - Szecsenyi, K. Meszaros
AU  - Todorović, N.
AU  - Petković, Marijana
AU  - Vasić, Vesna M.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3653
AB  - The kinetics of the reaction between the tetrachloroaurate(III) ion and L-methionine (L-Met) (0.1 M HClO4, pH 1.0-2.5) have been studied spectrophotometrically using a stopped-flow technique at different temperatures. Initially, the fast substitution reaction was ascribed to the formation of the short-lived square-planar Au(III)-(L-Met) that was followed by the replacement of a Cl- ligand and a subsequent, slower reduction to Au(I)-(L-Met). This is an intermolecular process, involving attack on the [AuCl4](-) Complex by an outer-sphere L-methionine. The activation parameters (Delta H-not equal and Delta S-not equal) for substitution and reduction were determined. IR spectroscopy indicates that L-methionine acts as a bidentate ligand, most likely coordinating via the S and N atoms, while H-1 and C-13 NMR data indicate methionine sulfoxide as the final product. Finally, the components of the reaction were treated thermally in order to investigate the solid phase synthesis of the resulting complex. (C) 2008 Elsevier Ltd. All rights reserved.
T2  - Polyhedron
T1  - Mechanism of complex formation between [AuCl4](-) and L-methionine
VL  - 28
IS  - 3
SP  - 593
EP  - 599
DO  - 10.1016/j.poly.2008.11.045
ER  - 

@article{
author = "Vujačić, Ana V. and Savić, Jasmina and Sovilj, Sofija P. and Szecsenyi, K. Meszaros and Todorović, N. and Petković, Marijana and Vasić, Vesna M.",
year = "2009",
abstract = "The kinetics of the reaction between the tetrachloroaurate(III) ion and L-methionine (L-Met) (0.1 M HClO4, pH 1.0-2.5) have been studied spectrophotometrically using a stopped-flow technique at different temperatures. Initially, the fast substitution reaction was ascribed to the formation of the short-lived square-planar Au(III)-(L-Met) that was followed by the replacement of a Cl- ligand and a subsequent, slower reduction to Au(I)-(L-Met). This is an intermolecular process, involving attack on the [AuCl4](-) Complex by an outer-sphere L-methionine. The activation parameters (Delta H-not equal and Delta S-not equal) for substitution and reduction were determined. IR spectroscopy indicates that L-methionine acts as a bidentate ligand, most likely coordinating via the S and N atoms, while H-1 and C-13 NMR data indicate methionine sulfoxide as the final product. Finally, the components of the reaction were treated thermally in order to investigate the solid phase synthesis of the resulting complex. (C) 2008 Elsevier Ltd. All rights reserved.",
journal = "Polyhedron",
title = "Mechanism of complex formation between [AuCl4](-) and L-methionine",
volume = "28",
number = "3",
pages = "593-599",
doi = "10.1016/j.poly.2008.11.045"
}

Vujačić, A. V., Savić, J., Sovilj, S. P., Szecsenyi, K. M., Todorović, N., Petković, M.,& Vasić, V. M.. (2009). Mechanism of complex formation between [AuCl4](-) and L-methionine. in Polyhedron, 28(3), 593-599.
https://doi.org/10.1016/j.poly.2008.11.045

Vujačić AV, Savić J, Sovilj SP, Szecsenyi KM, Todorović N, Petković M, Vasić VM. Mechanism of complex formation between [AuCl4](-) and L-methionine. in Polyhedron. 2009;28(3):593-599.
doi:10.1016/j.poly.2008.11.045 .

Vujačić, Ana V., Savić, Jasmina, Sovilj, Sofija P., Szecsenyi, K. Meszaros, Todorović, N., Petković, Marijana, Vasić, Vesna M., "Mechanism of complex formation between [AuCl4](-) and L-methionine" in Polyhedron, 28, no. 3 (2009):593-599,
https://doi.org/10.1016/j.poly.2008.11.045 . .

TY  - JOUR
AU  - Gulicovski, Jelena J.
AU  - Milonjić, Slobodan K.
AU  - Szecsenyi, K. Meszaros
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3900
AB  - Stable colloidal aqueous dispersions (sols) of cerium (IV) oxide of uniform size distribution were obtained by forced hydrolysis of cerium (IV) ions in the presence of diluted sulfuric or nitric acids. Synthesis of ceria sols was carried out using two commercially available precursors: Ce(SO4)(2) center dot 4H(2)O salt and 0.25 mol/L Ce(NO3)(4) aqueous solution. The precursors were dissolved in different concentrations of diluted sulfuric or nitric acid. After aging for various periods of time (2-24 h), the sols were cooled at room temperature. Sulfate and nitrate ions were removed from the sols particles by ultrafiltration. Characterization of the synthesized ceria sols has been made by X-ray diffraction, nitrogen adsorption/desorption, and DSC-TGA thermal analysis, as well as IR spectroscopy. Particle sizes, measured using a Zetasizer Nano equipped with a MPT-2 Autotitrator, range from 20 to 600 nm.
T2  - Materials and Manufacturing Processes
T1  - Synthesis and Characterization of Stable Aqueous Ceria Sols
VL  - 24
IS  - 10-11
SP  - 1080
EP  - 1085
DO  - 10.1080/10426910903032162
ER  - 

@article{
author = "Gulicovski, Jelena J. and Milonjić, Slobodan K. and Szecsenyi, K. Meszaros",
year = "2009",
abstract = "Stable colloidal aqueous dispersions (sols) of cerium (IV) oxide of uniform size distribution were obtained by forced hydrolysis of cerium (IV) ions in the presence of diluted sulfuric or nitric acids. Synthesis of ceria sols was carried out using two commercially available precursors: Ce(SO4)(2) center dot 4H(2)O salt and 0.25 mol/L Ce(NO3)(4) aqueous solution. The precursors were dissolved in different concentrations of diluted sulfuric or nitric acid. After aging for various periods of time (2-24 h), the sols were cooled at room temperature. Sulfate and nitrate ions were removed from the sols particles by ultrafiltration. Characterization of the synthesized ceria sols has been made by X-ray diffraction, nitrogen adsorption/desorption, and DSC-TGA thermal analysis, as well as IR spectroscopy. Particle sizes, measured using a Zetasizer Nano equipped with a MPT-2 Autotitrator, range from 20 to 600 nm.",
journal = "Materials and Manufacturing Processes",
title = "Synthesis and Characterization of Stable Aqueous Ceria Sols",
volume = "24",
number = "10-11",
pages = "1080-1085",
doi = "10.1080/10426910903032162"
}

Gulicovski, J. J., Milonjić, S. K.,& Szecsenyi, K. M.. (2009). Synthesis and Characterization of Stable Aqueous Ceria Sols. in Materials and Manufacturing Processes, 24(10-11), 1080-1085.
https://doi.org/10.1080/10426910903032162

Gulicovski JJ, Milonjić SK, Szecsenyi KM. Synthesis and Characterization of Stable Aqueous Ceria Sols. in Materials and Manufacturing Processes. 2009;24(10-11):1080-1085.
doi:10.1080/10426910903032162 .

Gulicovski, Jelena J., Milonjić, Slobodan K., Szecsenyi, K. Meszaros, "Synthesis and Characterization of Stable Aqueous Ceria Sols" in Materials and Manufacturing Processes, 24, no. 10-11 (2009):1080-1085,
https://doi.org/10.1080/10426910903032162 . .