TY  - JOUR
AU  - Todosijević, Anka
AU  - Bugarinović, Jovana
AU  - Pešić, Marko
AU  - Stevanović, Dragana
AU  - Damljanović, Ivan
AU  - Mihailović, Vladimir
AU  - Srećković, Nikola
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13262
AB  - The pyrazoline pharmacophore is the source of numerous biological activities. The synthesis and biological evaluation of new pyrazoline heterocycles is the first step in the development of new potential drugs. Therefore, ferrocene-containing 1-(thio)acetyl pyrazolines were synthesized to test their in vitro antimicrobial activity. All new heterocycles were characterized by standard spectroscopy methods due to confirmation of the structures. In addition, single-crystal X-ray analyses were performed for three representative pyrazole derivatives. Their electrochemical properties were investigated by cyclic voltammetry indicating a reversible one-electron redox couple originating from the ferrocene/ferrocenium pair. All obtained products were evaluated for their antibacterial and antifungal activity. It has been shown that pyrazolines have slightly better antifungal activity compared with their antibacterial activity.
T2  - Polyhedron
T1  - Synthesis, characterization, and antimicrobial activity of novel ferrocene-containing 1-(thio)acetyl pyrazolines
VL  - 258
SP  - 117028
DO  - 10.1016/j.poly.2024.117028
ER  - 

@article{
author = "Todosijević, Anka and Bugarinović, Jovana and Pešić, Marko and Stevanović, Dragana and Damljanović, Ivan and Mihailović, Vladimir and Srećković, Nikola and Novaković, Slađana B. and Bogdanović, Goran A.",
year = "2024",
abstract = "The pyrazoline pharmacophore is the source of numerous biological activities. The synthesis and biological evaluation of new pyrazoline heterocycles is the first step in the development of new potential drugs. Therefore, ferrocene-containing 1-(thio)acetyl pyrazolines were synthesized to test their in vitro antimicrobial activity. All new heterocycles were characterized by standard spectroscopy methods due to confirmation of the structures. In addition, single-crystal X-ray analyses were performed for three representative pyrazole derivatives. Their electrochemical properties were investigated by cyclic voltammetry indicating a reversible one-electron redox couple originating from the ferrocene/ferrocenium pair. All obtained products were evaluated for their antibacterial and antifungal activity. It has been shown that pyrazolines have slightly better antifungal activity compared with their antibacterial activity.",
journal = "Polyhedron",
title = "Synthesis, characterization, and antimicrobial activity of novel ferrocene-containing 1-(thio)acetyl pyrazolines",
volume = "258",
pages = "117028",
doi = "10.1016/j.poly.2024.117028"
}

Todosijević, A., Bugarinović, J., Pešić, M., Stevanović, D., Damljanović, I., Mihailović, V., Srećković, N., Novaković, S. B.,& Bogdanović, G. A.. (2024). Synthesis, characterization, and antimicrobial activity of novel ferrocene-containing 1-(thio)acetyl pyrazolines. in Polyhedron, 258, 117028.
https://doi.org/10.1016/j.poly.2024.117028

Todosijević A, Bugarinović J, Pešić M, Stevanović D, Damljanović I, Mihailović V, Srećković N, Novaković SB, Bogdanović GA. Synthesis, characterization, and antimicrobial activity of novel ferrocene-containing 1-(thio)acetyl pyrazolines. in Polyhedron. 2024;258:117028.
doi:10.1016/j.poly.2024.117028 .

Todosijević, Anka, Bugarinović, Jovana, Pešić, Marko, Stevanović, Dragana, Damljanović, Ivan, Mihailović, Vladimir, Srećković, Nikola, Novaković, Slađana B., Bogdanović, Goran A., "Synthesis, characterization, and antimicrobial activity of novel ferrocene-containing 1-(thio)acetyl pyrazolines" in Polyhedron, 258 (2024):117028,
https://doi.org/10.1016/j.poly.2024.117028 . .