TY  - JOUR
AU  - Ivković, Ivana
AU  - Bukvički, Danka
AU  - Novaković, Miroslav M.
AU  - Majstorović, Ivana
AU  - Leskovac, Andreja
AU  - Petrović, Sandra
AU  - Veljić, Milan
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10051
AB  - Liverworts are characterized by a high content of bioactive compounds reported to show antimicrobial, anticancer, and antioxidant properties. In this study, the biological effects of the methanol extract of the liverwort Pellia endiviifolia and its constituents, bis-bibenzyls perrottetin E, 10′-hydroxyperrottetin E, and 10,10′-dihydroxyperrottetin E, were investigated using human peripheral blood cells as a model system. The assessment of the investigated compounds comprised testing their genotoxicity, apoptotic potential, and redox modulating activities. The genotoxicity testing indicated that medium (25 µM) and high concentrations (100 µM) of the investigated compounds displayed genotoxic and antiproliferative effects in human lymphocytes as revealed by significant, concentration-dependent enhancement of the micronuclei incidence and decrease in the cytokinesis-block proliferation index compared to the control (P <.001). Analysis of leukocyte apoptosis showed a substantial potential of all investigated compounds to induce apoptosis, which was not concentration-dependent. The P endiviifolia extract and perrottetin E demonstrated considerable pro-apoptotic potential, even at the lowest concentration (1 µM) applied. Evaluation of the redox modulating effects, which comprised measuring erythrocyte catalase activity and the lymphocyte malondialdehyde level, showed that the investigated compounds did not induce oxidative stress in human peripheral blood cells (P >.05). The observed genotoxic, antiproliferative, and proapoptotic effects of the investigated compounds make them suitable for further comprehensive studies related to their possible applications as anticancer agents.
T2  - Natural Product Communications
T1  - Assessment of the Biological Effects of Pellia endiviifolia and its Constituents in Vitro
VL  - 16
IS  - 11
SP  - 1
DO  - 10.1177/1934578X211056422
ER  - 

@article{
author = "Ivković, Ivana and Bukvički, Danka and Novaković, Miroslav M. and Majstorović, Ivana and Leskovac, Andreja and Petrović, Sandra and Veljić, Milan",
year = "2021",
abstract = "Liverworts are characterized by a high content of bioactive compounds reported to show antimicrobial, anticancer, and antioxidant properties. In this study, the biological effects of the methanol extract of the liverwort Pellia endiviifolia and its constituents, bis-bibenzyls perrottetin E, 10′-hydroxyperrottetin E, and 10,10′-dihydroxyperrottetin E, were investigated using human peripheral blood cells as a model system. The assessment of the investigated compounds comprised testing their genotoxicity, apoptotic potential, and redox modulating activities. The genotoxicity testing indicated that medium (25 µM) and high concentrations (100 µM) of the investigated compounds displayed genotoxic and antiproliferative effects in human lymphocytes as revealed by significant, concentration-dependent enhancement of the micronuclei incidence and decrease in the cytokinesis-block proliferation index compared to the control (P <.001). Analysis of leukocyte apoptosis showed a substantial potential of all investigated compounds to induce apoptosis, which was not concentration-dependent. The P endiviifolia extract and perrottetin E demonstrated considerable pro-apoptotic potential, even at the lowest concentration (1 µM) applied. Evaluation of the redox modulating effects, which comprised measuring erythrocyte catalase activity and the lymphocyte malondialdehyde level, showed that the investigated compounds did not induce oxidative stress in human peripheral blood cells (P >.05). The observed genotoxic, antiproliferative, and proapoptotic effects of the investigated compounds make them suitable for further comprehensive studies related to their possible applications as anticancer agents.",
journal = "Natural Product Communications",
title = "Assessment of the Biological Effects of Pellia endiviifolia and its Constituents in Vitro",
volume = "16",
number = "11",
pages = "1",
doi = "10.1177/1934578X211056422"
}

Ivković, I., Bukvički, D., Novaković, M. M., Majstorović, I., Leskovac, A., Petrović, S.,& Veljić, M.. (2021). Assessment of the Biological Effects of Pellia endiviifolia and its Constituents in Vitro. in Natural Product Communications, 16(11), 1.
https://doi.org/10.1177/1934578X211056422

Ivković I, Bukvički D, Novaković MM, Majstorović I, Leskovac A, Petrović S, Veljić M. Assessment of the Biological Effects of Pellia endiviifolia and its Constituents in Vitro. in Natural Product Communications. 2021;16(11):1.
doi:10.1177/1934578X211056422 .

Ivković, Ivana, Bukvički, Danka, Novaković, Miroslav M., Majstorović, Ivana, Leskovac, Andreja, Petrović, Sandra, Veljić, Milan, "Assessment of the Biological Effects of Pellia endiviifolia and its Constituents in Vitro" in Natural Product Communications, 16, no. 11 (2021):1,
https://doi.org/10.1177/1934578X211056422 . .

TY  - JOUR
AU  - Marković, Dragan
AU  - Veljić, Milan
AU  - Simonović, Vojislav
AU  - Čebela, Maria
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10725
AB  - The principle of rotating sizing machines based on a division of the fruits of various geometrical characteristics of the gaps of the same dimensions are typical for any given class separately. The classes are deployed from the smallest to the largest in the direction of rotation of the disk, and arc sizing board can be mixed performance, as slope metering gape and step metering gape. This paper discusses the movement of fruit in relation of their speed, and analyzes the model for determining the capacity of rotating sizing machines for different kinds of fresh fruit and deep-frozen raspberries. Mass flow calibrator or capacity for fruits tested in this paper are similar to those obtained in some other known methods. Calibrated mass flow is proportional to the weight of fruit and fruit in inverse proportion to the diameter of treated fruit.
AB  - Princip rada rotirajućih diskosnih kalibratora zasniva se na odvajanju plodova različitih geometrijskih karakteristika kroz zazore odgovarajućih dimenzija karakterističnih za svaku zadatu klasu posebno. Klase su raspoređene od najmanje do najveće u smeru rotacije diska, a lučna kalibraciona pregrada može biti dvojake izvedbe, sa konstantno opadajućom širinom zazora i sa kaskadnom širinom. U ovom radu se razmatra kretanje plodova sa aspekta njihove brzine, i analizira model za određivanje kapaciteta rotacionih diskosnih kalibratora za različite vrste svežeg voća kao i za duboko zamrznutu malinu. Maseni protoci odnosno kapaciteti kalibratora za ispitane vrste voća u radu su približni onim koji su dobijeni nekim drugim poznatim metodama. Maseni protok kalibriranog voća srazmeran je masi i obrnuto srazmeran prečniku plodova za tretirano voće.
T2  - Journal on Processing and Energy in Agriculture
T1  - Modeling the flow of fresh and deep frozen calibrated fruit by rotating sizing machines
T1  - Modeliranje protoka kalibrisanog svežeg i duboko zamrznutog voća na rotacionim diskosnim kalibratorima
VL  - 15
IS  - 2
SP  - 67
EP  - 70
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10725
ER  - 

@article{
author = "Marković, Dragan and Veljić, Milan and Simonović, Vojislav and Čebela, Maria",
year = "2011",
abstract = "The principle of rotating sizing machines based on a division of the fruits of various geometrical characteristics of the gaps of the same dimensions are typical for any given class separately. The classes are deployed from the smallest to the largest in the direction of rotation of the disk, and arc sizing board can be mixed performance, as slope metering gape and step metering gape. This paper discusses the movement of fruit in relation of their speed, and analyzes the model for determining the capacity of rotating sizing machines for different kinds of fresh fruit and deep-frozen raspberries. Mass flow calibrator or capacity for fruits tested in this paper are similar to those obtained in some other known methods. Calibrated mass flow is proportional to the weight of fruit and fruit in inverse proportion to the diameter of treated fruit., Princip rada rotirajućih diskosnih kalibratora zasniva se na odvajanju plodova različitih geometrijskih karakteristika kroz zazore odgovarajućih dimenzija karakterističnih za svaku zadatu klasu posebno. Klase su raspoređene od najmanje do najveće u smeru rotacije diska, a lučna kalibraciona pregrada može biti dvojake izvedbe, sa konstantno opadajućom širinom zazora i sa kaskadnom širinom. U ovom radu se razmatra kretanje plodova sa aspekta njihove brzine, i analizira model za određivanje kapaciteta rotacionih diskosnih kalibratora za različite vrste svežeg voća kao i za duboko zamrznutu malinu. Maseni protoci odnosno kapaciteti kalibratora za ispitane vrste voća u radu su približni onim koji su dobijeni nekim drugim poznatim metodama. Maseni protok kalibriranog voća srazmeran je masi i obrnuto srazmeran prečniku plodova za tretirano voće.",
journal = "Journal on Processing and Energy in Agriculture",
title = "Modeling the flow of fresh and deep frozen calibrated fruit by rotating sizing machines, Modeliranje protoka kalibrisanog svežeg i duboko zamrznutog voća na rotacionim diskosnim kalibratorima",
volume = "15",
number = "2",
pages = "67-70",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10725"
}

Marković, D., Veljić, M., Simonović, V.,& Čebela, M.. (2011). Modeling the flow of fresh and deep frozen calibrated fruit by rotating sizing machines. in Journal on Processing and Energy in Agriculture, 15(2), 67-70.
https://hdl.handle.net/21.15107/rcub_vinar_10725

Marković D, Veljić M, Simonović V, Čebela M. Modeling the flow of fresh and deep frozen calibrated fruit by rotating sizing machines. in Journal on Processing and Energy in Agriculture. 2011;15(2):67-70.
https://hdl.handle.net/21.15107/rcub_vinar_10725 .

Marković, Dragan, Veljić, Milan, Simonović, Vojislav, Čebela, Maria, "Modeling the flow of fresh and deep frozen calibrated fruit by rotating sizing machines" in Journal on Processing and Energy in Agriculture, 15, no. 2 (2011):67-70,
https://hdl.handle.net/21.15107/rcub_vinar_10725 .