@conference{
author = "Aćimović, D. and Rogić Miladinović, Zorana and Cvetićanin, Jelena and Trpkov, Đorđe and Nešković, Olivera M.",
year = "2012",
abstract = "Collagen is the most frequently occuring fibrillar protein in mammals, which can be found in cartilage, tendon, bone, ligament, skin, etc. The structure of collagen is based on a complicated helix structure of single chains of amino acids (most abundant is glicine-Gly, proline-Pro and hydroxyproline-Hyp) which are connected by hydrogen bonds. We tried to establish MALDI method to get better resolution of collagen’s mass spectra. Digested collagen (type II from bovine Achilles tendon which was digested with collagenase from Clostridium histolycium) has been analysed on MALDI-TOF MS in order to find peptide’s fragments that are characteristic for collagen. In mass spetra we found peaks of peptides, which is highly indicative for collagen (GlyPro-Hyp, Gly-Pro-Asp, Gly-Pro-Glu ect.) We hope that it should be possible to obtain MS analysis and structure characterization of collagen by MALDI-TOF/TOF in future.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "YUCOMAT 2012 : 14th Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts",
title = "MALDI TOF Mass Spectrometry Characterization of Collagen",
pages = "112-112",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12403"
}