TY  - JOUR
AU  - Petković, Marijana
AU  - Schiller, Jürgen
AU  - Mueller, Matthias
AU  - Suess, Rosmarie
AU  - Arnold, Klaus
AU  - Arnhold, Juergen
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3770
AB  - It is usually accepted that neutral phospholipids (PLs) generate singly positively charged ions, whereas negative PLs are easily detectable in the negative ion mode when analysed by matrix-assisted laser desorption and ionisation time-of-flight mass spectrometry (MALDI-TOF MS). In this study, we demonstrate that some caution is required in the interpretation of MALDI-TOF mass spectra of PLs, since also neutral PLs have appeared to be detectable in the negative ion mode as well. Neutral and negatively charged phospholipids can generate adducts with the most commonly used matrix - 2,5-dihydroxybenzoic acid - yielding singly negatively charged ions that are detectable in the spectra. This further contributes to the complexity of the spectra and potentially leads to severe misinterpretation, particularly when unknown mixtures of PLs are analysed by MALDI-TOF MS.
T2  - Zeitschrift fur Naturforschung. Section B: Journal of Chemical Sciences
T1  - Detection of Adducts with Matrix Clusters in the Positive and Negative Ion Mode MALDI-TOF Mass Spectra of Phospholipids
VL  - 64
IS  - 3
SP  - 331
EP  - 334
DO  - 10.1515/znb-2009-0314
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3770
ER  - 

@article{
author = "Petković, Marijana and Schiller, Jürgen and Mueller, Matthias and Suess, Rosmarie and Arnold, Klaus and Arnhold, Juergen",
year = "2009",
abstract = "It is usually accepted that neutral phospholipids (PLs) generate singly positively charged ions, whereas negative PLs are easily detectable in the negative ion mode when analysed by matrix-assisted laser desorption and ionisation time-of-flight mass spectrometry (MALDI-TOF MS). In this study, we demonstrate that some caution is required in the interpretation of MALDI-TOF mass spectra of PLs, since also neutral PLs have appeared to be detectable in the negative ion mode as well. Neutral and negatively charged phospholipids can generate adducts with the most commonly used matrix - 2,5-dihydroxybenzoic acid - yielding singly negatively charged ions that are detectable in the spectra. This further contributes to the complexity of the spectra and potentially leads to severe misinterpretation, particularly when unknown mixtures of PLs are analysed by MALDI-TOF MS.",
journal = "Zeitschrift fur Naturforschung. Section B: Journal of Chemical Sciences",
title = "Detection of Adducts with Matrix Clusters in the Positive and Negative Ion Mode MALDI-TOF Mass Spectra of Phospholipids",
volume = "64",
number = "3",
pages = "331-334",
doi = "10.1515/znb-2009-0314",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3770"
}

Petković, M., Schiller, J., Mueller, M., Suess, R., Arnold, K.,& Arnhold, J.. (2009). Detection of Adducts with Matrix Clusters in the Positive and Negative Ion Mode MALDI-TOF Mass Spectra of Phospholipids. in Zeitschrift fur Naturforschung. Section B: Journal of Chemical Sciences, 64(3), 331-334.
https://doi.org/10.1515/znb-2009-0314
https://hdl.handle.net/21.15107/rcub_vinar_3770

Petković M, Schiller J, Mueller M, Suess R, Arnold K, Arnhold J. Detection of Adducts with Matrix Clusters in the Positive and Negative Ion Mode MALDI-TOF Mass Spectra of Phospholipids. in Zeitschrift fur Naturforschung. Section B: Journal of Chemical Sciences. 2009;64(3):331-334.
doi:10.1515/znb-2009-0314
https://hdl.handle.net/21.15107/rcub_vinar_3770 .

Petković, Marijana, Schiller, Jürgen, Mueller, Matthias, Suess, Rosmarie, Arnold, Klaus, Arnhold, Juergen, "Detection of Adducts with Matrix Clusters in the Positive and Negative Ion Mode MALDI-TOF Mass Spectra of Phospholipids" in Zeitschrift fur Naturforschung. Section B: Journal of Chemical Sciences, 64, no. 3 (2009):331-334,
https://doi.org/10.1515/znb-2009-0314 .,
https://hdl.handle.net/21.15107/rcub_vinar_3770 .