TY  - JOUR
AU  - Đorđević, Jelena
AU  - Lazarević, Nataša
AU  - Zdjelarević, Nevena
AU  - Arbutina, Dalibor
AU  - Forkapić, Sofija
AU  - Janković, Marija
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12101
AB  - The main purpose of this paper was to determine tritium concentration in surface water samples, using liquid scintillation counting. Surface water samples were collected from the Mlaka creek on three different locations near PC „Nuclear Facilities of Serbia“. The importance of tritium monitoring around nuclear reactors and nuclear waste storages is due to prevention of possible internal exposure through ingestion of drinking waters with elevated levels of tritium from existing water supply in their nearby. Tritium concentrations that have been measured during the period from 2017 to 2022 ranged from less than 2 Bq/L to 103 Bq/L.
AB  - Glavni cilj ovog rada bio je da se utvrdi koncentracija tricijuma u uzorcima površinske vode. Korišćena metoda bila je tečna scintilaciona spektrometrija. Uzorci površinske vode uzeti su iz potoka Mlaka na tri različite lokacije u blizini JP „Nuklearni objekti Srbije“. Značaj monitoringa tricijuma oko nuklearnih reaktora i skladišta nuklearnog otpada je sprečavanje unutrašnjeg izlaganja unošenjenjem vode za piće sa povišenim nivoom tricijuma iz postojećih izvora vodosnabdevanja u njihovoj blizini. Koncentracije tricijuma koje su izmerene u periodu od 2017. do 2022. godine kretale su se od manje od 2 Bq/L do 103 Bq/L.
T2  - Scientific Technical Review
T1  - Determination of Tritium Concentration in Mlaka Creek
T1  - Određivanje koncentracije tricijuma u potoku Mlaka
VL  - 73
IS  - 1
SP  - 38
EP  - 41
DO  - 10.1016/j.tet.2020.131456
DO  - 10.5937/str2301038D
ER  - 

@article{
author = "Đorđević, Jelena and Lazarević, Nataša and Zdjelarević, Nevena and Arbutina, Dalibor and Forkapić, Sofija and Janković, Marija",
year = "2023",
abstract = "The main purpose of this paper was to determine tritium concentration in surface water samples, using liquid scintillation counting. Surface water samples were collected from the Mlaka creek on three different locations near PC „Nuclear Facilities of Serbia“. The importance of tritium monitoring around nuclear reactors and nuclear waste storages is due to prevention of possible internal exposure through ingestion of drinking waters with elevated levels of tritium from existing water supply in their nearby. Tritium concentrations that have been measured during the period from 2017 to 2022 ranged from less than 2 Bq/L to 103 Bq/L., Glavni cilj ovog rada bio je da se utvrdi koncentracija tricijuma u uzorcima površinske vode. Korišćena metoda bila je tečna scintilaciona spektrometrija. Uzorci površinske vode uzeti su iz potoka Mlaka na tri različite lokacije u blizini JP „Nuklearni objekti Srbije“. Značaj monitoringa tricijuma oko nuklearnih reaktora i skladišta nuklearnog otpada je sprečavanje unutrašnjeg izlaganja unošenjenjem vode za piće sa povišenim nivoom tricijuma iz postojećih izvora vodosnabdevanja u njihovoj blizini. Koncentracije tricijuma koje su izmerene u periodu od 2017. do 2022. godine kretale su se od manje od 2 Bq/L do 103 Bq/L.",
journal = "Scientific Technical Review",
title = "Determination of Tritium Concentration in Mlaka Creek, Određivanje koncentracije tricijuma u potoku Mlaka",
volume = "73",
number = "1",
pages = "38-41",
doi = "10.1016/j.tet.2020.131456, 10.5937/str2301038D"
}

Đorđević, J., Lazarević, N., Zdjelarević, N., Arbutina, D., Forkapić, S.,& Janković, M.. (2023). Determination of Tritium Concentration in Mlaka Creek. in Scientific Technical Review, 73(1), 38-41.
https://doi.org/10.1016/j.tet.2020.131456

Đorđević J, Lazarević N, Zdjelarević N, Arbutina D, Forkapić S, Janković M. Determination of Tritium Concentration in Mlaka Creek. in Scientific Technical Review. 2023;73(1):38-41.
doi:10.1016/j.tet.2020.131456 .

Đorđević, Jelena, Lazarević, Nataša, Zdjelarević, Nevena, Arbutina, Dalibor, Forkapić, Sofija, Janković, Marija, "Determination of Tritium Concentration in Mlaka Creek" in Scientific Technical Review, 73, no. 1 (2023):38-41,
https://doi.org/10.1016/j.tet.2020.131456 . .

TY  - JOUR
AU  - Todorović Vukotić, Nevena
AU  - Đorđević, Jelena
AU  - Pejić, Snežana
AU  - Đorđević, Neda O.
AU  - Pajović, Snežana B.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9078
AB  - Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical presentations that can escalate to acute liver failure. The worldwide increase in the use of psychotropic drugs, their long-term use on a daily basis, common comorbidities of psychiatric and metabolic disorders, and polypharmacy in psychiatric patients increase the incidence of psychotropics-induced DILI. During the last 2 decades, hepatotoxicity of various antidepressants (ADs) and antipsychotics (APs) received much attention. Comprehensive review and discussion of accumulated literature data concerning this issue are performed in this study, as hepatotoxic effects of most commonly prescribed ADs and APs are classified, described, and discussed. The review focuses on ADs and APs characterized by the risk of causing liver damage and highlights the ones found to cause life-threatening or severe DILI cases. In parallel, an overview of hepatic oxidative stress, inflammation, and steatosis underlying DILI is provided, followed by extensive review and discussion of the pathophysiology of AD- and AP-induced DILI revealed in case reports, and animal and in vitro studies. The consequences of some ADs and APs ability to affect drug-metabolizing enzymes and therefore provoke drug–drug interactions are also addressed. Continuous collecting of data on drugs, mechanisms, and risk factors for DILI, as well as critical data reviewing, is crucial for easier DILI diagnosis and more efficient risk assessment of AD- and AP-induced DILI. Higher awareness of ADs and APs hepatotoxicity is the prerequisite for their safe use and optimal dosing. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.
T2  - Archives of Toxicology
T1  - Antidepressants- and antipsychotics-induced hepatotoxicity
VL  - 95
IS  - 3
SP  - 767
EP  - 789
DO  - 10.1007/s00204-020-02963-4
ER  - 

@article{
author = "Todorović Vukotić, Nevena and Đorđević, Jelena and Pejić, Snežana and Đorđević, Neda O. and Pajović, Snežana B.",
year = "2021",
abstract = "Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical presentations that can escalate to acute liver failure. The worldwide increase in the use of psychotropic drugs, their long-term use on a daily basis, common comorbidities of psychiatric and metabolic disorders, and polypharmacy in psychiatric patients increase the incidence of psychotropics-induced DILI. During the last 2 decades, hepatotoxicity of various antidepressants (ADs) and antipsychotics (APs) received much attention. Comprehensive review and discussion of accumulated literature data concerning this issue are performed in this study, as hepatotoxic effects of most commonly prescribed ADs and APs are classified, described, and discussed. The review focuses on ADs and APs characterized by the risk of causing liver damage and highlights the ones found to cause life-threatening or severe DILI cases. In parallel, an overview of hepatic oxidative stress, inflammation, and steatosis underlying DILI is provided, followed by extensive review and discussion of the pathophysiology of AD- and AP-induced DILI revealed in case reports, and animal and in vitro studies. The consequences of some ADs and APs ability to affect drug-metabolizing enzymes and therefore provoke drug–drug interactions are also addressed. Continuous collecting of data on drugs, mechanisms, and risk factors for DILI, as well as critical data reviewing, is crucial for easier DILI diagnosis and more efficient risk assessment of AD- and AP-induced DILI. Higher awareness of ADs and APs hepatotoxicity is the prerequisite for their safe use and optimal dosing. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.",
journal = "Archives of Toxicology",
title = "Antidepressants- and antipsychotics-induced hepatotoxicity",
volume = "95",
number = "3",
pages = "767-789",
doi = "10.1007/s00204-020-02963-4"
}

Todorović Vukotić, N., Đorđević, J., Pejić, S., Đorđević, N. O.,& Pajović, S. B.. (2021). Antidepressants- and antipsychotics-induced hepatotoxicity. in Archives of Toxicology, 95(3), 767-789.
https://doi.org/10.1007/s00204-020-02963-4

Todorović Vukotić N, Đorđević J, Pejić S, Đorđević NO, Pajović SB. Antidepressants- and antipsychotics-induced hepatotoxicity. in Archives of Toxicology. 2021;95(3):767-789.
doi:10.1007/s00204-020-02963-4 .

Todorović Vukotić, Nevena, Đorđević, Jelena, Pejić, Snežana, Đorđević, Neda O., Pajović, Snežana B., "Antidepressants- and antipsychotics-induced hepatotoxicity" in Archives of Toxicology, 95, no. 3 (2021):767-789,
https://doi.org/10.1007/s00204-020-02963-4 . .

TY  - CHAP
AU  - Radojčić, Marija
AU  - Adžić, Miroslav
AU  - Nićiforović, Ana
AU  - Đorđević, Jelena
AU  - Đorđević, Ana
AU  - Demonacos, Constantinos
AU  - Krstić-Demonacos, Marija
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12040
AB  - Chronic stress is recognized as an etiological factor for the onset and exacerbation of
many psychiatric disorders. Among chronic stressors, those of psychosocial and
emotional origin are considered of particular importance for prominent depletion of
physiological and psychological resources. The key mechanisms underlying deleterious
effects of chronic stress are thought to emerge from the compromised stress response at
the level of hypothalamic-pituitary-adrenal (HPA) axis feedback, and limbic brain
structures, such as hippocampus (HIPPO) and prefrontal cortex (PFC).
In this review we summarize and discuss effects of chronic psychosocial isolation
(CPSI) using animal model of male Wistar rats, housed individually for 21 days lacking
physical and visual contact. CPSI, as an important distress factor for normally gregarious
Wistar rats, resulted in diminishment of serum corticosterone and blood glucose, and did
not alter catecholamine levels, which opposes most other chronic stressors that elevate
stress hormones. In the context of possibly aberrant feedback mechanism at the molecular
level, we discuss altered glucocorticoid receptor (GR) distribution and appearance of GR
phosphoisoform excessively phosphorylated on serine 232 (pGR S232), as well as,
altered activities of JNK and CDK kinases that target GR for phosphorylation. The
appearance of pGR S232 in the nucleus and the mitochondria of HIPPO and PFC is
potentially related to a marked transcriptional activation/repression of several GR
regulated nuclear genes (GR itself, CRH, BDNF) and mitochondrial genes (COX1,
COX3). Another important stress and redox state sensitive transcription factor, nuclear factor kappa B (NFțB) is also discussed in terms of the disturbed redox balance
(illustrated by the altered ratio of the activity of an array of antioxidant enzymes) and
altered proapoptotic/proplastic signalling, since it regulates transcription of a wide array
of genes (like Bcl-2, NCAM). Such cellular conditions, provoked by CPSI, are also
shown to affect susceptibility to mitochondrially triggered apoptosis (illustrated by
redistribution of Bcl family members and DNA fragmentation, more prominent in the
PFC) and to simultaneously affect expression of main neural plasticity protein,
polysialylated NCAM (PSA-NCAM). In summary, we present novel causal connection
between the redox imbalance in the CNS, altered signalling via JNK and CDK kinases,
GR phosphorylation/transactivity and NFțB transactivity, as well as their cellular
imbalance, the parameters which all together yield inadequate CNS and systemic stress
response.
T2  - Horizons in Neuroscience Research
T1  - Effects of Chronic Psychosocial Isolation on Limbic Brain Structures of Wistar Rats
VL  - 5
SP  - 97
EP  - 126
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12040
ER  - 

@inbook{
author = "Radojčić, Marija and Adžić, Miroslav and Nićiforović, Ana and Đorđević, Jelena and Đorđević, Ana and Demonacos, Constantinos and Krstić-Demonacos, Marija",
year = "2011",
abstract = "Chronic stress is recognized as an etiological factor for the onset and exacerbation of
many psychiatric disorders. Among chronic stressors, those of psychosocial and
emotional origin are considered of particular importance for prominent depletion of
physiological and psychological resources. The key mechanisms underlying deleterious
effects of chronic stress are thought to emerge from the compromised stress response at
the level of hypothalamic-pituitary-adrenal (HPA) axis feedback, and limbic brain
structures, such as hippocampus (HIPPO) and prefrontal cortex (PFC).
In this review we summarize and discuss effects of chronic psychosocial isolation
(CPSI) using animal model of male Wistar rats, housed individually for 21 days lacking
physical and visual contact. CPSI, as an important distress factor for normally gregarious
Wistar rats, resulted in diminishment of serum corticosterone and blood glucose, and did
not alter catecholamine levels, which opposes most other chronic stressors that elevate
stress hormones. In the context of possibly aberrant feedback mechanism at the molecular
level, we discuss altered glucocorticoid receptor (GR) distribution and appearance of GR
phosphoisoform excessively phosphorylated on serine 232 (pGR S232), as well as,
altered activities of JNK and CDK kinases that target GR for phosphorylation. The
appearance of pGR S232 in the nucleus and the mitochondria of HIPPO and PFC is
potentially related to a marked transcriptional activation/repression of several GR
regulated nuclear genes (GR itself, CRH, BDNF) and mitochondrial genes (COX1,
COX3). Another important stress and redox state sensitive transcription factor, nuclear factor kappa B (NFțB) is also discussed in terms of the disturbed redox balance
(illustrated by the altered ratio of the activity of an array of antioxidant enzymes) and
altered proapoptotic/proplastic signalling, since it regulates transcription of a wide array
of genes (like Bcl-2, NCAM). Such cellular conditions, provoked by CPSI, are also
shown to affect susceptibility to mitochondrially triggered apoptosis (illustrated by
redistribution of Bcl family members and DNA fragmentation, more prominent in the
PFC) and to simultaneously affect expression of main neural plasticity protein,
polysialylated NCAM (PSA-NCAM). In summary, we present novel causal connection
between the redox imbalance in the CNS, altered signalling via JNK and CDK kinases,
GR phosphorylation/transactivity and NFțB transactivity, as well as their cellular
imbalance, the parameters which all together yield inadequate CNS and systemic stress
response.",
journal = "Horizons in Neuroscience Research",
booktitle = "Effects of Chronic Psychosocial Isolation on Limbic Brain Structures of Wistar Rats",
volume = "5",
pages = "97-126",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12040"
}

Radojčić, M., Adžić, M., Nićiforović, A., Đorđević, J., Đorđević, A., Demonacos, C.,& Krstić-Demonacos, M.. (2011). Effects of Chronic Psychosocial Isolation on Limbic Brain Structures of Wistar Rats. in Horizons in Neuroscience Research, 5, 97-126.
https://hdl.handle.net/21.15107/rcub_vinar_12040

Radojčić M, Adžić M, Nićiforović A, Đorđević J, Đorđević A, Demonacos C, Krstić-Demonacos M. Effects of Chronic Psychosocial Isolation on Limbic Brain Structures of Wistar Rats. in Horizons in Neuroscience Research. 2011;5:97-126.
https://hdl.handle.net/21.15107/rcub_vinar_12040 .

Radojčić, Marija, Adžić, Miroslav, Nićiforović, Ana, Đorđević, Jelena, Đorđević, Ana, Demonacos, Constantinos, Krstić-Demonacos, Marija, "Effects of Chronic Psychosocial Isolation on Limbic Brain Structures of Wistar Rats" in Horizons in Neuroscience Research, 5 (2011):97-126,
https://hdl.handle.net/21.15107/rcub_vinar_12040 .

TY  - CONF
AU  - Đorđević, Jelena
AU  - Kalijadis, Ana
AU  - Kumrić, Ksenija
AU  - Jovanović, Zoran
AU  - Laušević, Zoran
AU  - Purenović, Milovan
AU  - Trtić-Petrović, Tatjana
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12784
AB  - This paper presents voltametric studies of the linuron insecticide (3-(3,4-dichlorophenyl)-1methoxy-1-methylureum) on a boron doped glassy carbon (GCB), glassy carbon (GC) prepared in our laboratory and commercial glassy carbon electrode. The method, operated in the differential pulse voltammetric mode, works in the concetracion range from 0.62 to 26.09       mg L-1. We determined a peak potential, Ep, (1.25V), linear range and LOD for linuron in the sulfuric acid as a supporting electrolyte (pH=0.7) for all applied electrodes. GCB shows the broadest linear range and sensitivity. This appears to be the first aplication of a boron doped glassy carbon electrode to the voltammetric determination of linuron insecticide.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - 9th Young Researchers' Conference 2010 - Materials Science and Engineering : Program and Book of Abstracts
T1  - Voltammetric determination of linuron insecticide in methanol using a boron doped, glassy carbon and commercial glassy carbon electrode
SP  - 37
EP  - 37
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12784
ER  - 

@conference{
author = "Đorđević, Jelena and Kalijadis, Ana and Kumrić, Ksenija and Jovanović, Zoran and Laušević, Zoran and Purenović, Milovan and Trtić-Petrović, Tatjana",
year = "2010",
abstract = "This paper presents voltametric studies of the linuron insecticide (3-(3,4-dichlorophenyl)-1methoxy-1-methylureum) on a boron doped glassy carbon (GCB), glassy carbon (GC) prepared in our laboratory and commercial glassy carbon electrode. The method, operated in the differential pulse voltammetric mode, works in the concetracion range from 0.62 to 26.09       mg L-1. We determined a peak potential, Ep, (1.25V), linear range and LOD for linuron in the sulfuric acid as a supporting electrolyte (pH=0.7) for all applied electrodes. GCB shows the broadest linear range and sensitivity. This appears to be the first aplication of a boron doped glassy carbon electrode to the voltammetric determination of linuron insecticide.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "9th Young Researchers' Conference 2010 - Materials Science and Engineering : Program and Book of Abstracts",
title = "Voltammetric determination of linuron insecticide in methanol using a boron doped, glassy carbon and commercial glassy carbon electrode",
pages = "37-37",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12784"
}

Đorđević, J., Kalijadis, A., Kumrić, K., Jovanović, Z., Laušević, Z., Purenović, M.,& Trtić-Petrović, T.. (2010). Voltammetric determination of linuron insecticide in methanol using a boron doped, glassy carbon and commercial glassy carbon electrode. in 9th Young Researchers' Conference 2010 - Materials Science and Engineering : Program and Book of Abstracts
Belgrade : Institute of Technical Sciences of SASA., 37-37.
https://hdl.handle.net/21.15107/rcub_vinar_12784

Đorđević J, Kalijadis A, Kumrić K, Jovanović Z, Laušević Z, Purenović M, Trtić-Petrović T. Voltammetric determination of linuron insecticide in methanol using a boron doped, glassy carbon and commercial glassy carbon electrode. in 9th Young Researchers' Conference 2010 - Materials Science and Engineering : Program and Book of Abstracts. 2010;:37-37.
https://hdl.handle.net/21.15107/rcub_vinar_12784 .

Đorđević, Jelena, Kalijadis, Ana, Kumrić, Ksenija, Jovanović, Zoran, Laušević, Zoran, Purenović, Milovan, Trtić-Petrović, Tatjana, "Voltammetric determination of linuron insecticide in methanol using a boron doped, glassy carbon and commercial glassy carbon electrode" in 9th Young Researchers' Conference 2010 - Materials Science and Engineering : Program and Book of Abstracts (2010):37-37,
https://hdl.handle.net/21.15107/rcub_vinar_12784 .