TY  - JOUR
AU  - Miodragović Đenana U.
AU  - Bogdanović, Goran A.
AU  - Miodragovic, Zoran M.
AU  - Radulovic, Milanka D.
AU  - Novaković, Slađana B.
AU  - Kaluđerović, Goran N.
AU  - Kozlowski, Henryk
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3091
AB  - Crystal structure of a novel cobalt(III) complex with antiulcer drug famotidine and ethylenediamine was determined. This is the second structure of a transition metal complex with famotidine resolved by a single crystal X-ray analysis, in which famotidine shows different mode of coordination than that observed in the other cases. Drug molecule is coordinated to metal ion as a tetradentate ligand through guanidine N6, thiazole N4, thioether S2 and terminal N3 atom. Two NH2 groups (N3H(2) and N6H(2)) are deprotonated and drug coordinates as dianion. In the asymmetric unit, one chloride anion and one water molecule were found to complete the complex stoichiometry. The structure of the complex is abundant in atoms, which can be involved in hydrogen bond formation either as hydrogen acceptors or hydrogen donors. Because of that, a great number of hydrogen bonds dominates the crystal packing. Beside the hydrogen bonds, there are two interesting noncovalent interactions: CH...pi and NH...pi within the famotidine anion, which stabilize the complex structure. The pi...pi stacking interactions between neighboring complex cations are also observed. Antibacterial and antifungal activity of famotidine and its newly synthesized complex against representative bacteria: Escherichia coli, Staphilococcus aureus and Micrococcus lysodeikticus and fungi: Aspergillus niger and Candida albicans were examined. The results indicate a higher selectivity of the famotidine-Co(III) complex, as well as better growth inhibitory activity (lower MIC values (MIC, minimal inhibitory concentration)) in comparison with the drug alone. (c) 2006 Elsevier Inc. All rights reserved.
T2  - Journal of Inorganic Biochemistry
T1  - Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex
VL  - 100
IS  - 9
SP  - 1568
EP  - 1574
DO  - 10.1016/j.jinorgbio.2006.05.009
ER  - 

@article{
author = "Miodragović Đenana U. and Bogdanović, Goran A. and Miodragovic, Zoran M. and Radulovic, Milanka D. and Novaković, Slađana B. and Kaluđerović, Goran N. and Kozlowski, Henryk",
year = "2006",
abstract = "Crystal structure of a novel cobalt(III) complex with antiulcer drug famotidine and ethylenediamine was determined. This is the second structure of a transition metal complex with famotidine resolved by a single crystal X-ray analysis, in which famotidine shows different mode of coordination than that observed in the other cases. Drug molecule is coordinated to metal ion as a tetradentate ligand through guanidine N6, thiazole N4, thioether S2 and terminal N3 atom. Two NH2 groups (N3H(2) and N6H(2)) are deprotonated and drug coordinates as dianion. In the asymmetric unit, one chloride anion and one water molecule were found to complete the complex stoichiometry. The structure of the complex is abundant in atoms, which can be involved in hydrogen bond formation either as hydrogen acceptors or hydrogen donors. Because of that, a great number of hydrogen bonds dominates the crystal packing. Beside the hydrogen bonds, there are two interesting noncovalent interactions: CH...pi and NH...pi within the famotidine anion, which stabilize the complex structure. The pi...pi stacking interactions between neighboring complex cations are also observed. Antibacterial and antifungal activity of famotidine and its newly synthesized complex against representative bacteria: Escherichia coli, Staphilococcus aureus and Micrococcus lysodeikticus and fungi: Aspergillus niger and Candida albicans were examined. The results indicate a higher selectivity of the famotidine-Co(III) complex, as well as better growth inhibitory activity (lower MIC values (MIC, minimal inhibitory concentration)) in comparison with the drug alone. (c) 2006 Elsevier Inc. All rights reserved.",
journal = "Journal of Inorganic Biochemistry",
title = "Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex",
volume = "100",
number = "9",
pages = "1568-1574",
doi = "10.1016/j.jinorgbio.2006.05.009"
}

Miodragović Đenana U., Bogdanović, G. A., Miodragovic, Z. M., Radulovic, M. D., Novaković, S. B., Kaluđerović, G. N.,& Kozlowski, H.. (2006). Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex. in Journal of Inorganic Biochemistry, 100(9), 1568-1574.
https://doi.org/10.1016/j.jinorgbio.2006.05.009

Miodragović Đenana U., Bogdanović GA, Miodragovic ZM, Radulovic MD, Novaković SB, Kaluđerović GN, Kozlowski H. Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex. in Journal of Inorganic Biochemistry. 2006;100(9):1568-1574.
doi:10.1016/j.jinorgbio.2006.05.009 .

Miodragović Đenana U., Bogdanović, Goran A., Miodragovic, Zoran M., Radulovic, Milanka D., Novaković, Slađana B., Kaluđerović, Goran N., Kozlowski, Henryk, "Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex" in Journal of Inorganic Biochemistry, 100, no. 9 (2006):1568-1574,
https://doi.org/10.1016/j.jinorgbio.2006.05.009 . .

TY  - JOUR
AU  - Kaluđerović, Goran N.
AU  - Bogdanović, Goran A.
AU  - Sabo, Tibor J.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3132
AB  - C8H18Cl4N2O4Pt, monoclinic, P12(1)/n1 (no. 14), a = 8.181(3) angstrom, b = 10.303(5) angstrom, c = 9.073(6) angstrom, beta = 103.2(1)degrees, V = 744.6 angstrom(3), Z = 2, R-gt(F) = 0.080, wR(ref)(F-2) = 0.247, T = 293 K.
T2  - Zeitschrift für Kristallographie - New Crystal Structures
T1  - Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]
VL  - 221
IS  - 3
SP  - 345
EP  - 346
DO  - 10.1524/ncrs.2006.0103
ER  - 

@article{
author = "Kaluđerović, Goran N. and Bogdanović, Goran A. and Sabo, Tibor J.",
year = "2006",
abstract = "C8H18Cl4N2O4Pt, monoclinic, P12(1)/n1 (no. 14), a = 8.181(3) angstrom, b = 10.303(5) angstrom, c = 9.073(6) angstrom, beta = 103.2(1)degrees, V = 744.6 angstrom(3), Z = 2, R-gt(F) = 0.080, wR(ref)(F-2) = 0.247, T = 293 K.",
journal = "Zeitschrift für Kristallographie - New Crystal Structures",
title = "Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]",
volume = "221",
number = "3",
pages = "345-346",
doi = "10.1524/ncrs.2006.0103"
}

Kaluđerović, G. N., Bogdanović, G. A.,& Sabo, T. J.. (2006). Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]. in Zeitschrift für Kristallographie - New Crystal Structures, 221(3), 345-346.
https://doi.org/10.1524/ncrs.2006.0103

Kaluđerović GN, Bogdanović GA, Sabo TJ. Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]. in Zeitschrift für Kristallographie - New Crystal Structures. 2006;221(3):345-346.
doi:10.1524/ncrs.2006.0103 .

Kaluđerović, Goran N., Bogdanović, Goran A., Sabo, Tibor J., "Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]" in Zeitschrift für Kristallographie - New Crystal Structures, 221, no. 3 (2006):345-346,
https://doi.org/10.1524/ncrs.2006.0103 . .

TY  - JOUR
AU  - Sabo, Tibor J.
AU  - Dinovic, VA
AU  - Kaluđerović, Goran N.
AU  - Stanojković, Tatjana P.
AU  - Bogdanović, Goran A.
AU  - Juranic, ZD
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2876
AB  - Four platinum(IV) complexes, trans,trans-dichlorobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Cl-2] (1) and trans.trans-dibromobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Br-2] (2), as well as, trans,trans-dichlorobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Cl-2] (3) and trans,trans-dibromobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Br-2] (4) (with configuration index for all complexes OC-6-14), were synthesized and characterized by elemental analysis, infrared and H-1 NMR spectroscopy. In the aim to assess the selectivity in the antitumor action of these complexes, the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells; to human myelogenous leukemia K562 cells and to normal immunocompetent cells; i.e., on human PBMC. The details of the crystal structure synthesized trans,trans-[Pt(sar)(2)Br-2] complex were also reported here. In the crystal structure of trans, trans-[Pt(sar)(2)Br-2] the Pt(IV) ion had a deformed octahedral coordination with both N-methylglycinates and bromides bonded trans to one another and with the NPt-Br bond angles of 84.1(4) and 95.9(4)degrees. The trans, trans-[Pt(sar)(2)Br-2] complex molecules form 2D-layers with multiple N-H (...) O and C-H (...) O hydrogen bonds. (c) 2005 Elsevier B.V. All rights reserved.
T2  - Inorganica Chimica Acta
T1  - Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC
VL  - 358
IS  - 7
SP  - 2239
EP  - 2245
DO  - 10.1016/j.ica.2005.01.007
ER  - 

@article{
author = "Sabo, Tibor J. and Dinovic, VA and Kaluđerović, Goran N. and Stanojković, Tatjana P. and Bogdanović, Goran A. and Juranic, ZD",
year = "2005",
abstract = "Four platinum(IV) complexes, trans,trans-dichlorobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Cl-2] (1) and trans.trans-dibromobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Br-2] (2), as well as, trans,trans-dichlorobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Cl-2] (3) and trans,trans-dibromobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Br-2] (4) (with configuration index for all complexes OC-6-14), were synthesized and characterized by elemental analysis, infrared and H-1 NMR spectroscopy. In the aim to assess the selectivity in the antitumor action of these complexes, the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells; to human myelogenous leukemia K562 cells and to normal immunocompetent cells; i.e., on human PBMC. The details of the crystal structure synthesized trans,trans-[Pt(sar)(2)Br-2] complex were also reported here. In the crystal structure of trans, trans-[Pt(sar)(2)Br-2] the Pt(IV) ion had a deformed octahedral coordination with both N-methylglycinates and bromides bonded trans to one another and with the NPt-Br bond angles of 84.1(4) and 95.9(4)degrees. The trans, trans-[Pt(sar)(2)Br-2] complex molecules form 2D-layers with multiple N-H (...) O and C-H (...) O hydrogen bonds. (c) 2005 Elsevier B.V. All rights reserved.",
journal = "Inorganica Chimica Acta",
title = "Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC",
volume = "358",
number = "7",
pages = "2239-2245",
doi = "10.1016/j.ica.2005.01.007"
}

Sabo, T. J., Dinovic, V., Kaluđerović, G. N., Stanojković, T. P., Bogdanović, G. A.,& Juranic, Z.. (2005). Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC. in Inorganica Chimica Acta, 358(7), 2239-2245.
https://doi.org/10.1016/j.ica.2005.01.007

Sabo TJ, Dinovic V, Kaluđerović GN, Stanojković TP, Bogdanović GA, Juranic Z. Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC. in Inorganica Chimica Acta. 2005;358(7):2239-2245.
doi:10.1016/j.ica.2005.01.007 .

Sabo, Tibor J., Dinovic, VA, Kaluđerović, Goran N., Stanojković, Tatjana P., Bogdanović, Goran A., Juranic, ZD, "Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC" in Inorganica Chimica Acta, 358, no. 7 (2005):2239-2245,
https://doi.org/10.1016/j.ica.2005.01.007 . .

TY  - JOUR
AU  - Kaluđerović, Goran N.
AU  - Bogdanović, Goran A.
AU  - Sabo, Tibor J.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2539
AB  - This paper reports the first synthesized Pt(IV) complex with ethylenediamine-N,N-di-3-propionato ligand (eddp). The crystal structure of trans-[Pt(eddp)Cl-2] . H2O complex has been determined. Pt(IV) has a distorted octahedral coordination due to an intramolecular N-H...Cl interaction.
T2  - Journal of Coordination Chemistry
T1  - Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate
VL  - 55
IS  - 7
SP  - 817
EP  - 822
DO  - 10.1080/0095897022000001566
ER  - 

@article{
author = "Kaluđerović, Goran N. and Bogdanović, Goran A. and Sabo, Tibor J.",
year = "2002",
abstract = "This paper reports the first synthesized Pt(IV) complex with ethylenediamine-N,N-di-3-propionato ligand (eddp). The crystal structure of trans-[Pt(eddp)Cl-2] . H2O complex has been determined. Pt(IV) has a distorted octahedral coordination due to an intramolecular N-H...Cl interaction.",
journal = "Journal of Coordination Chemistry",
title = "Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate",
volume = "55",
number = "7",
pages = "817-822",
doi = "10.1080/0095897022000001566"
}

Kaluđerović, G. N., Bogdanović, G. A.,& Sabo, T. J.. (2002). Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate. in Journal of Coordination Chemistry, 55(7), 817-822.
https://doi.org/10.1080/0095897022000001566

Kaluđerović GN, Bogdanović GA, Sabo TJ. Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate. in Journal of Coordination Chemistry. 2002;55(7):817-822.
doi:10.1080/0095897022000001566 .

Kaluđerović, Goran N., Bogdanović, Goran A., Sabo, Tibor J., "Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate" in Journal of Coordination Chemistry, 55, no. 7 (2002):817-822,
https://doi.org/10.1080/0095897022000001566 . .