TY  - DATA
AU  - Cvijetic, Ilija N.
AU  - Verbic, Tatjana Z.
AU  - Drakulić, Branko J.
AU  - Stanković, Dalibor M.
AU  - Juranić, Ivan O.
AU  - Manojlović, Dragan D.
AU  - Zloh, Mire
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8851
AB  - Supplementary material to Cvijetić, I., Verbić, T., Drakulić, B. J., Stanković, D., Juranić, I. O., Manojlović, D. D., & Zloh, M. (2017). Redox properties of alkyl-substituted 4-aryl-2, 4-dioxobutanoic acids. Journal of the Serbian Chemical Society, 82(3), 303-316.
T2  - Journal of the Serbian Chemical Society
T1  - Supplementary material to Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids
VL  - 82
IS  - 3
SP  - S158
EP  - S187
DO  - 10.2298/JSC161118021C
ER  - 

@misc{
author = "Cvijetic, Ilija N. and Verbic, Tatjana Z. and Drakulić, Branko J. and Stanković, Dalibor M. and Juranić, Ivan O. and Manojlović, Dragan D. and Zloh, Mire",
year = "2017",
abstract = "Supplementary material to Cvijetić, I., Verbić, T., Drakulić, B. J., Stanković, D., Juranić, I. O., Manojlović, D. D., & Zloh, M. (2017). Redox properties of alkyl-substituted 4-aryl-2, 4-dioxobutanoic acids. Journal of the Serbian Chemical Society, 82(3), 303-316.",
journal = "Journal of the Serbian Chemical Society",
title = "Supplementary material to Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids",
volume = "82",
number = "3",
pages = "S158-S187",
doi = "10.2298/JSC161118021C"
}

Cvijetic, I. N., Verbic, T. Z., Drakulić, B. J., Stanković, D. M., Juranić, I. O., Manojlović, D. D.,& Zloh, M.. (2017). Supplementary material to Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids. in Journal of the Serbian Chemical Society, 82(3), S158-S187.
https://doi.org/10.2298/JSC161118021C

Cvijetic IN, Verbic TZ, Drakulić BJ, Stanković DM, Juranić IO, Manojlović DD, Zloh M. Supplementary material to Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids. in Journal of the Serbian Chemical Society. 2017;82(3):S158-S187.
doi:10.2298/JSC161118021C .

Cvijetic, Ilija N., Verbic, Tatjana Z., Drakulić, Branko J., Stanković, Dalibor M., Juranić, Ivan O., Manojlović, Dragan D., Zloh, Mire, "Supplementary material to Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids" in Journal of the Serbian Chemical Society, 82, no. 3 (2017):S158-S187,
https://doi.org/10.2298/JSC161118021C . .

TY  - JOUR
AU  - Cvijetic, Ilija N.
AU  - Verbic, Tatjana Z.
AU  - Drakulić, Branko J.
AU  - Stanković, Dalibor M.
AU  - Juranić, Ivan O.
AU  - Manojlović, Dragan D.
AU  - Zloh, Mire
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1570
AB  - Redox properties of a set of aryldiketo acids (ADKs), small organic molecules that comprise 2,4-dioxobutanoic acid moiety, were studied. Along with well-known HIV-1 integrase (IN) inhibition, ADKs exert widespread biological activities. The aim of this work was to evaluate the effects of aryl substitutions on the properties of the dioxobutanoic moiety that is involved in key interactions with metal ions within the active sites of target enzymes. The effect of pH on the electronic properties of nine congeners was examined using cyclic voltammetry and differential pulse polarography. The compounds were chosen as a simple set of congeners bearing Me-groups on the phenyl ring, which should not be involved in electrochemical reactions, leaving the diketo moiety as the sole electrophore. The substitution pattern was systematically varied, yielding a set having different torsion between the phenyl ring and the aryl keto group (Ar-C(O)). The protonation state of the ADKs at different pH values was determined from the experimentally obtained pK(a) values. The results showed that an equal number of protons and electrons were involved in the oxidation and reduction reactions at the surface of the electrode. Quantitative linear correlations were found between the reduction potentials and the energies of the frontier orbitals, calculated for neutral, mono-anionic and the corresponding radical anionic species, and the steric parameter as two independent variables.
T2  - Journal of the Serbian Chemical Society
T1  - Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids
VL  - 82
IS  - 3
SP  - 303
EP  - 316
DO  - 10.2298/JSC161118021C
ER  - 

@article{
author = "Cvijetic, Ilija N. and Verbic, Tatjana Z. and Drakulić, Branko J. and Stanković, Dalibor M. and Juranić, Ivan O. and Manojlović, Dragan D. and Zloh, Mire",
year = "2017",
abstract = "Redox properties of a set of aryldiketo acids (ADKs), small organic molecules that comprise 2,4-dioxobutanoic acid moiety, were studied. Along with well-known HIV-1 integrase (IN) inhibition, ADKs exert widespread biological activities. The aim of this work was to evaluate the effects of aryl substitutions on the properties of the dioxobutanoic moiety that is involved in key interactions with metal ions within the active sites of target enzymes. The effect of pH on the electronic properties of nine congeners was examined using cyclic voltammetry and differential pulse polarography. The compounds were chosen as a simple set of congeners bearing Me-groups on the phenyl ring, which should not be involved in electrochemical reactions, leaving the diketo moiety as the sole electrophore. The substitution pattern was systematically varied, yielding a set having different torsion between the phenyl ring and the aryl keto group (Ar-C(O)). The protonation state of the ADKs at different pH values was determined from the experimentally obtained pK(a) values. The results showed that an equal number of protons and electrons were involved in the oxidation and reduction reactions at the surface of the electrode. Quantitative linear correlations were found between the reduction potentials and the energies of the frontier orbitals, calculated for neutral, mono-anionic and the corresponding radical anionic species, and the steric parameter as two independent variables.",
journal = "Journal of the Serbian Chemical Society",
title = "Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids",
volume = "82",
number = "3",
pages = "303-316",
doi = "10.2298/JSC161118021C"
}

Cvijetic, I. N., Verbic, T. Z., Drakulić, B. J., Stanković, D. M., Juranić, I. O., Manojlović, D. D.,& Zloh, M.. (2017). Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids. in Journal of the Serbian Chemical Society, 82(3), 303-316.
https://doi.org/10.2298/JSC161118021C

Cvijetic IN, Verbic TZ, Drakulić BJ, Stanković DM, Juranić IO, Manojlović DD, Zloh M. Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids. in Journal of the Serbian Chemical Society. 2017;82(3):303-316.
doi:10.2298/JSC161118021C .

Cvijetic, Ilija N., Verbic, Tatjana Z., Drakulić, Branko J., Stanković, Dalibor M., Juranić, Ivan O., Manojlović, Dragan D., Zloh, Mire, "Redox properties of alkyl-substituted 4-aryl-2,4-dioxobutanoic acids" in Journal of the Serbian Chemical Society, 82, no. 3 (2017):303-316,
https://doi.org/10.2298/JSC161118021C . .