TY  - JOUR
AU  - Švorc, Lubomir
AU  - Strežova, Ivana
AU  - Kianičkova, Kristina
AU  - Stanković, Dalibor M.
AU  - Otrisal, Pavel
AU  - Samphao, Anchalee
PY  - 2018
UR  - https://linkinghub.elsevier.com/retrieve/pii/S1572665718303783
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7698
AB  - Herein, an advanced electroanalytical approach for the determination of ibuprofen based on the use of a bare and electrochemically untreated boron-doped diamond electrode is presented. Cyclic voltammetric study revealed that the electrode reaction of the analyte was manifested by the presence of well-shaped irreversible and diffusion-driven oxidation peak at very high potential (+1.75 V vs. Ag/AgCl/3 mol L−1KCl reference electrode) in 1 mol L−1perchloric acid. After optimization of experimental conditions, the peak current of ibuprofen was proportionally linear from 9.49 × 10−7to 6.69 × 10−5mol L−1providing both differential pulse (DPV) and square-wave voltammetric (SWV) techniques, respectively. The elaborated electroanalytical protocol rendered low detection limits of 4.1 × 10−7and 9.3 × 10−7mol L−1in association with favourable intra-day repeatability (relative standard deviation of 3.6 and 4.6%) using DPV and SWV procedures, respectively. The effect of interfering compounds such as ascorbic acid, dopamine, caffeine, uric acid and glucose on the current response of ibuprofen was explored in details. The usefulness of the proposed approach was verified in the analysis of a variety of commercial brands of pharmaceuticals and spiked human urine samples with the significant range of recovery percentages (for pharmaceuticals: 99.8–107.5% and 99.8–105.0% by DPV and SWV, for urine: 95–107% and 97–103% by DPV and SWV). Taking these features into account, the developed protocol may be exploited as a novel, simple and efficient tool in drug quality control analysis and analysis of biological samples. In addition, a bare and electrochemically untreated boron-doped diamond electrode may be applied as a progressive electrochemical sensor and helpful alternative to previously utilized electrochemical platforms in this field.
T2  - Journal of Electroanalytical Chemistry
T1  - An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode
VL  - 822
SP  - 144
EP  - 152
DO  - 10.1016/j.jelechem.2018.05.026
ER  - 

@article{
author = "Švorc, Lubomir and Strežova, Ivana and Kianičkova, Kristina and Stanković, Dalibor M. and Otrisal, Pavel and Samphao, Anchalee",
year = "2018",
abstract = "Herein, an advanced electroanalytical approach for the determination of ibuprofen based on the use of a bare and electrochemically untreated boron-doped diamond electrode is presented. Cyclic voltammetric study revealed that the electrode reaction of the analyte was manifested by the presence of well-shaped irreversible and diffusion-driven oxidation peak at very high potential (+1.75 V vs. Ag/AgCl/3 mol L−1KCl reference electrode) in 1 mol L−1perchloric acid. After optimization of experimental conditions, the peak current of ibuprofen was proportionally linear from 9.49 × 10−7to 6.69 × 10−5mol L−1providing both differential pulse (DPV) and square-wave voltammetric (SWV) techniques, respectively. The elaborated electroanalytical protocol rendered low detection limits of 4.1 × 10−7and 9.3 × 10−7mol L−1in association with favourable intra-day repeatability (relative standard deviation of 3.6 and 4.6%) using DPV and SWV procedures, respectively. The effect of interfering compounds such as ascorbic acid, dopamine, caffeine, uric acid and glucose on the current response of ibuprofen was explored in details. The usefulness of the proposed approach was verified in the analysis of a variety of commercial brands of pharmaceuticals and spiked human urine samples with the significant range of recovery percentages (for pharmaceuticals: 99.8–107.5% and 99.8–105.0% by DPV and SWV, for urine: 95–107% and 97–103% by DPV and SWV). Taking these features into account, the developed protocol may be exploited as a novel, simple and efficient tool in drug quality control analysis and analysis of biological samples. In addition, a bare and electrochemically untreated boron-doped diamond electrode may be applied as a progressive electrochemical sensor and helpful alternative to previously utilized electrochemical platforms in this field.",
journal = "Journal of Electroanalytical Chemistry",
title = "An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode",
volume = "822",
pages = "144-152",
doi = "10.1016/j.jelechem.2018.05.026"
}

Švorc, L., Strežova, I., Kianičkova, K., Stanković, D. M., Otrisal, P.,& Samphao, A.. (2018). An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode. in Journal of Electroanalytical Chemistry, 822, 144-152.
https://doi.org/10.1016/j.jelechem.2018.05.026

Švorc L, Strežova I, Kianičkova K, Stanković DM, Otrisal P, Samphao A. An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode. in Journal of Electroanalytical Chemistry. 2018;822:144-152.
doi:10.1016/j.jelechem.2018.05.026 .

Švorc, Lubomir, Strežova, Ivana, Kianičkova, Kristina, Stanković, Dalibor M., Otrisal, Pavel, Samphao, Anchalee, "An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode" in Journal of Electroanalytical Chemistry, 822 (2018):144-152,
https://doi.org/10.1016/j.jelechem.2018.05.026 . .