TY  - JOUR
AU  - Perendija, Branka R.
AU  - Despotović, Svetlana G.
AU  - Radovanovic, Tijana B.
AU  - Gavric, Jelena P.
AU  - Mitić, Slavica S. Borkovic
AU  - Pavlović, Slađan
AU  - Ognjanovic, Branka I.
AU  - Simic, Snezana B.
AU  - Pajović, Snežana B.
AU  - Saičić, Zorica S.
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4652
AB  - We investigated the biochemical and ultrastructural changes in the liver of the freshwater fish, European perch (Perca fluviatilis), in response to Aphanizomenon flos-aquae bloom in the Gruza Reservoir, Serbia. The activities of total manganese- and copper zinc-containing superoxide dismutase (Tot SOD, Mn-SOD, Cu/Zn-SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and biotransformation phase II enzyme glutathione-S-transferase (GST), as well as concentrations of total glutathione (GSH) and sulfhydryl (-SH) groups were examined before and during the bloom period. Mn-SOD activity was significantly higher, while the activities of Cu/Zn-SOD, CAT and GSH-Px and the concentration of the -SH groups were significantly lower during the bloom. The ultrastructure of the liver revealed necrotic and apoptotic damage to the hepatocytes during the bloom period. Our work represents the first study to report the influences of an Aphanizomenon flos-aquae bloom in the Gruza Reservoir on antioxidant biomarkers and on histopathological alterations in the liver of the freshwater fish European perch (Perca fluviatilis).
T2  - Archives of Biological Sciences
T1  - Biochemical and Ultrastructural Changes in the Liver of European Perch (Perca Fluviatilis L.) in Response to Cyanobacterial Bloom in the Gruza Reservoir
VL  - 63
IS  - 4
SP  - 979
EP  - 989
DO  - 10.2298/ABS1104979P
ER  - 

@article{
author = "Perendija, Branka R. and Despotović, Svetlana G. and Radovanovic, Tijana B. and Gavric, Jelena P. and Mitić, Slavica S. Borkovic and Pavlović, Slađan and Ognjanovic, Branka I. and Simic, Snezana B. and Pajović, Snežana B. and Saičić, Zorica S.",
year = "2011",
abstract = "We investigated the biochemical and ultrastructural changes in the liver of the freshwater fish, European perch (Perca fluviatilis), in response to Aphanizomenon flos-aquae bloom in the Gruza Reservoir, Serbia. The activities of total manganese- and copper zinc-containing superoxide dismutase (Tot SOD, Mn-SOD, Cu/Zn-SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and biotransformation phase II enzyme glutathione-S-transferase (GST), as well as concentrations of total glutathione (GSH) and sulfhydryl (-SH) groups were examined before and during the bloom period. Mn-SOD activity was significantly higher, while the activities of Cu/Zn-SOD, CAT and GSH-Px and the concentration of the -SH groups were significantly lower during the bloom. The ultrastructure of the liver revealed necrotic and apoptotic damage to the hepatocytes during the bloom period. Our work represents the first study to report the influences of an Aphanizomenon flos-aquae bloom in the Gruza Reservoir on antioxidant biomarkers and on histopathological alterations in the liver of the freshwater fish European perch (Perca fluviatilis).",
journal = "Archives of Biological Sciences",
title = "Biochemical and Ultrastructural Changes in the Liver of European Perch (Perca Fluviatilis L.) in Response to Cyanobacterial Bloom in the Gruza Reservoir",
volume = "63",
number = "4",
pages = "979-989",
doi = "10.2298/ABS1104979P"
}

Perendija, B. R., Despotović, S. G., Radovanovic, T. B., Gavric, J. P., Mitić, S. S. B., Pavlović, S., Ognjanovic, B. I., Simic, S. B., Pajović, S. B.,& Saičić, Z. S.. (2011). Biochemical and Ultrastructural Changes in the Liver of European Perch (Perca Fluviatilis L.) in Response to Cyanobacterial Bloom in the Gruza Reservoir. in Archives of Biological Sciences, 63(4), 979-989.
https://doi.org/10.2298/ABS1104979P

Perendija BR, Despotović SG, Radovanovic TB, Gavric JP, Mitić SSB, Pavlović S, Ognjanovic BI, Simic SB, Pajović SB, Saičić ZS. Biochemical and Ultrastructural Changes in the Liver of European Perch (Perca Fluviatilis L.) in Response to Cyanobacterial Bloom in the Gruza Reservoir. in Archives of Biological Sciences. 2011;63(4):979-989.
doi:10.2298/ABS1104979P .

Perendija, Branka R., Despotović, Svetlana G., Radovanovic, Tijana B., Gavric, Jelena P., Mitić, Slavica S. Borkovic, Pavlović, Slađan, Ognjanovic, Branka I., Simic, Snezana B., Pajović, Snežana B., Saičić, Zorica S., "Biochemical and Ultrastructural Changes in the Liver of European Perch (Perca Fluviatilis L.) in Response to Cyanobacterial Bloom in the Gruza Reservoir" in Archives of Biological Sciences, 63, no. 4 (2011):979-989,
https://doi.org/10.2298/ABS1104979P . .