@article{
author = "Pejović, Anka and Stevanović, Dragana D. and Damljanović, Ivan S. and Vukićević, Mirjana and Novaković, Slađana B. and Bogdanović, Goran A. and Mihajilov-Krstev, Tatjana and Radulovic, Niko and Vukićević, Rastko D.",
year = "2012",
abstract = "A successful aza-Michael addition of arylamines to a conjugated enone, acryloylferrocene, has been achieved by ultrasonic irradiation of the mixture of these reactants and the catalyst, i.e., montmorillonite K-10. This solvent-free reaction, yielding ferrocene containing Mannich bases, 3-(arylamino)-1-ferrocenylpropan-1-ones, considered as valuable precursors in organic synthesis, has been performed by using a simple ultrasonic cleaner. Among 17 synthesized beta-amino ketones, three were new ones, and these were fully characterized by spectroscopic means. X-Ray crystallographic analysis of three of these crystalline products enabled the insight into the conformational details of these compounds. All compounds were evaluated for their antibacterial activities against six Gram-positive and five Gram-negative strains in a microdilution assay. The observed promising antibacterial activity (with a MIC value of 25 mu g/ml (ca. 0.07 mu mol/ml) as the best result for almost all tested compounds against Micrococcus flavus) seems not only to be compound but also bacterial species-specific.",
journal = "Helvetica Chimica Acta",
title = "Ultrasound-Assisted Synthesis of 3-(Arylamino)-1-ferrocenylpropan-1-ones",
volume = "95",
number = "8",
pages = "1425-1441",
doi = "10.1002/hlca.201200009"
}