TY  - JOUR
AU  - Antonijević, Đorđe
AU  - Despotović, Ana
AU  - Biočanin, Vladimir
AU  - Milošević, Miloš
AU  - Trišić, Dijana
AU  - Lazović, Vladimir M.
AU  - Zogović, Nevena
AU  - Milašin, Jelena
AU  - Ilić, Dragan V.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9880
AB  - The purpose of this study was to investigate the influence of different radiopacifiers on the physicochemical and biological properties of novel calcium silicate based endodontic ceramic enriched with bioactive nano-particulated hydroxyapatite – ECHA. Namely, ECHA was used as a basis for mixing with the following radiopacifiers: strontium fluoride (SrF2), zirconium dioxide (ZrO2) and bismuth oxide (Bi2O3). For comparison, Portland cement (PC) and mineral trioxide aggregate (MTA) were used. The following physicochemical characteristics were examined: the radiopacity, setting time, compressive strength, porosity, wettability and pH value. The biocompatibility of the cements was assessed by crystal violet, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) and cell adhesion assays. The highest radiopacity was obtained for the ECHA + Bi2O3 mixture and MTA that were statistically significant in comparison to other materials (p < 0.05). Both initial and final setting times as well as compressive strengths were statistically lower for experimental cements than for PC and MTA (p < 0.05). The lowest total porosity was observed in the ECHA + ZrO2 group when compared with the other two experimental cements (p < 0.05), but not when compared with PC and MTA (p > 0.05). Experimental cements exhibited statistically higher contact angles of glycerol than PC and MTA (p < 0.05). For blood plasma, a statistical difference was found only between ECHA + Bi2O3 and PC (p < 0.05). All investigated materials had alkalization ability. Cell viability assays revealed that the extracts of tested cements did not exhibit cytotoxic effect on L929 cells. Scanning electron microscopy had shown a high degree of cell proliferation and adhesion of cells from apical papilla on experimental cements’ surfaces. Novel endodontic ceramics with nano-hydroxyapatite addition have satisfactory biological and physicochemical properties when compared to MTA and PC controls. Considerable lower setting time of experimental cements might present a huge advantage of these synthesized materials in clinical practice. SrF2 presents a novel promising radiopacifying agent for dental cements manufacturing.
T2  - Ceramics International
T1  - Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic
VL  - 47
IS  - 20
SP  - 28913
EP  - 28923
DO  - 10.1016/j.ceramint.2021.07.052
ER  - 

@article{
author = "Antonijević, Đorđe and Despotović, Ana and Biočanin, Vladimir and Milošević, Miloš and Trišić, Dijana and Lazović, Vladimir M. and Zogović, Nevena and Milašin, Jelena and Ilić, Dragan V.",
year = "2021",
abstract = "The purpose of this study was to investigate the influence of different radiopacifiers on the physicochemical and biological properties of novel calcium silicate based endodontic ceramic enriched with bioactive nano-particulated hydroxyapatite – ECHA. Namely, ECHA was used as a basis for mixing with the following radiopacifiers: strontium fluoride (SrF2), zirconium dioxide (ZrO2) and bismuth oxide (Bi2O3). For comparison, Portland cement (PC) and mineral trioxide aggregate (MTA) were used. The following physicochemical characteristics were examined: the radiopacity, setting time, compressive strength, porosity, wettability and pH value. The biocompatibility of the cements was assessed by crystal violet, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) and cell adhesion assays. The highest radiopacity was obtained for the ECHA + Bi2O3 mixture and MTA that were statistically significant in comparison to other materials (p < 0.05). Both initial and final setting times as well as compressive strengths were statistically lower for experimental cements than for PC and MTA (p < 0.05). The lowest total porosity was observed in the ECHA + ZrO2 group when compared with the other two experimental cements (p < 0.05), but not when compared with PC and MTA (p > 0.05). Experimental cements exhibited statistically higher contact angles of glycerol than PC and MTA (p < 0.05). For blood plasma, a statistical difference was found only between ECHA + Bi2O3 and PC (p < 0.05). All investigated materials had alkalization ability. Cell viability assays revealed that the extracts of tested cements did not exhibit cytotoxic effect on L929 cells. Scanning electron microscopy had shown a high degree of cell proliferation and adhesion of cells from apical papilla on experimental cements’ surfaces. Novel endodontic ceramics with nano-hydroxyapatite addition have satisfactory biological and physicochemical properties when compared to MTA and PC controls. Considerable lower setting time of experimental cements might present a huge advantage of these synthesized materials in clinical practice. SrF2 presents a novel promising radiopacifying agent for dental cements manufacturing.",
journal = "Ceramics International",
title = "Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic",
volume = "47",
number = "20",
pages = "28913-28923",
doi = "10.1016/j.ceramint.2021.07.052"
}

Antonijević, Đ., Despotović, A., Biočanin, V., Milošević, M., Trišić, D., Lazović, V. M., Zogović, N., Milašin, J.,& Ilić, D. V.. (2021). Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic. in Ceramics International, 47(20), 28913-28923.
https://doi.org/10.1016/j.ceramint.2021.07.052

Antonijević Đ, Despotović A, Biočanin V, Milošević M, Trišić D, Lazović VM, Zogović N, Milašin J, Ilić DV. Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic. in Ceramics International. 2021;47(20):28913-28923.
doi:10.1016/j.ceramint.2021.07.052 .

Antonijević, Đorđe, Despotović, Ana, Biočanin, Vladimir, Milošević, Miloš, Trišić, Dijana, Lazović, Vladimir M., Zogović, Nevena, Milašin, Jelena, Ilić, Dragan V., "Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic" in Ceramics International, 47, no. 20 (2021):28913-28923,
https://doi.org/10.1016/j.ceramint.2021.07.052 . .

TY  - JOUR
AU  - Ilić, Dragan V.
AU  - Stojanović, Ljiljana
AU  - Antonijević,Đorđe
AU  - Milutinović-Smiljanić, Sanja
AU  - Savić-Stanković, Tatjana
AU  - Milosavljević, Željko
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9641
AB  - Radiological diagnostics serves as one of the basic monitoring techniques in veterinary dental practice. The recent up-to-date literature data based on the findings of digital radiology/radiovisiography (RVG) in general dentistry inspired the authors to present its possible use in clinical veterinary dentistry. The digital radiography used in this study was RVG Trophy Radiologie SA 2001 device equipped with software for linear measurements (readings), densitometry, setting of contrast of radiography image, 3D image manipulation, zooming of detail and orientation handling. The aim of the study was to evaluate the bone mineral density of the alveolar part of the lower jaw in seven Scottish terriers. Bone mineral density measurement was performed around the central lower incisors by converting gray scale values into equivalent aluminum thickness (mm Al). The mean bone mineral density was in the range of 4.31-6.20 mm Al with no significant statistical difference between left and right incisors (p>0.01). Our results showed that the combination of RVG and aluminum step wedge etalon is a reliable tool to measure bone mineral density around the lower central incisors in dogs. This method can be considered as comfortable for manipulation in everyday use in clinical veterinary practice.
T2  - Acta Veterinaria
T1  - Measuring of mandible bone density in dogs using/digital radiography/radiovisigraphy
VL  - 70
IS  - 3
SP  - 285
EP  - 295
DO  - 10.2478/acve-2020-0021
ER  - 

@article{
author = "Ilić, Dragan V. and Stojanović, Ljiljana and Antonijević,Đorđe and Milutinović-Smiljanić, Sanja and Savić-Stanković, Tatjana and Milosavljević, Željko",
year = "2020",
abstract = "Radiological diagnostics serves as one of the basic monitoring techniques in veterinary dental practice. The recent up-to-date literature data based on the findings of digital radiology/radiovisiography (RVG) in general dentistry inspired the authors to present its possible use in clinical veterinary dentistry. The digital radiography used in this study was RVG Trophy Radiologie SA 2001 device equipped with software for linear measurements (readings), densitometry, setting of contrast of radiography image, 3D image manipulation, zooming of detail and orientation handling. The aim of the study was to evaluate the bone mineral density of the alveolar part of the lower jaw in seven Scottish terriers. Bone mineral density measurement was performed around the central lower incisors by converting gray scale values into equivalent aluminum thickness (mm Al). The mean bone mineral density was in the range of 4.31-6.20 mm Al with no significant statistical difference between left and right incisors (p>0.01). Our results showed that the combination of RVG and aluminum step wedge etalon is a reliable tool to measure bone mineral density around the lower central incisors in dogs. This method can be considered as comfortable for manipulation in everyday use in clinical veterinary practice.",
journal = "Acta Veterinaria",
title = "Measuring of mandible bone density in dogs using/digital radiography/radiovisigraphy",
volume = "70",
number = "3",
pages = "285-295",
doi = "10.2478/acve-2020-0021"
}

Ilić, D. V., Stojanović, L., Antonijević, Đ., Milutinović-Smiljanić, S., Savić-Stanković, T.,& Milosavljević, Ž.. (2020). Measuring of mandible bone density in dogs using/digital radiography/radiovisigraphy. in Acta Veterinaria, 70(3), 285-295.
https://doi.org/10.2478/acve-2020-0021

Ilić DV, Stojanović L, Antonijević Đ, Milutinović-Smiljanić S, Savić-Stanković T, Milosavljević Ž. Measuring of mandible bone density in dogs using/digital radiography/radiovisigraphy. in Acta Veterinaria. 2020;70(3):285-295.
doi:10.2478/acve-2020-0021 .

Ilić, Dragan V., Stojanović, Ljiljana, Antonijević,Đorđe, Milutinović-Smiljanić, Sanja, Savić-Stanković, Tatjana, Milosavljević, Željko, "Measuring of mandible bone density in dogs using/digital radiography/radiovisigraphy" in Acta Veterinaria, 70, no. 3 (2020):285-295,
https://doi.org/10.2478/acve-2020-0021 . .