TY  - JOUR
AU  - Vučetić, Milan
AU  - Roganović, Jelena
AU  - Freilich, M.
AU  - Shafer, D.
AU  - Milić, Marija
AU  - Đukić, Ljiljana
AU  - Petrović, Nina
AU  - Marković, Evgenija
AU  - Marković, Aleksa
AU  - Brković, Božidar
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13113
AB  - Objective: To evaluate an association between bone levels of inflammation/oxidative stress mediators and postoperative discomfort after third molar conventional or piezosurgery. Material and methods: Twenty-six subjects with bilaterally impacted mandibular third molars, who underwent either piezo or conventional surgery, were included in a split-mouth design study. MicroRNA-21 (miR-21) expression, interleukin-1 beta (IL-1β), and vascular endothelial growth factor (VEGF) proteins, as well as superoxide dismutase (SOD) activity in alveolar bone, were evaluated. Pain intensity, the first pain appearance, analgesic first use and total dose taken, trismus, and swelling were clinically recorded. Results: MiR-21 expression was higher while VEGF protein was lower in piezosurgery vs. conventional groups. The differences in IL-1β protein and SOD activity were not significant between groups. The pain intensity on the first day was significantly decreased in piezosurgery group. The first pain appearance and the first analgesic taken were reported sooner in conventional vs. piezosurgical group. Significantly pronounced trismus on the third day following conventional surgery was found. In conventional group, significantly increased trismus was observed on the third compared to the first postoperative day. MiR-21 showed significant correlation with the first pain appearance. Conclusion: Delayed onset of less pronounced postoperative pain after piezosurgical vs. conventional extraction of impacted lower third molar was significantly associated with expression of bone miR-21. Clinical relevance: Alveolar bone miR-21 may reflect surgical stress and is associated with third molar postoperative pain onset.
T2  - Clinical Oral Investigations
T1  - Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort
VL  - 25
IS  - 1
SP  - 319
EP  - 328
DO  - 10.1007/s00784-020-03366-6
ER  - 

@article{
author = "Vučetić, Milan and Roganović, Jelena and Freilich, M. and Shafer, D. and Milić, Marija and Đukić, Ljiljana and Petrović, Nina and Marković, Evgenija and Marković, Aleksa and Brković, Božidar",
year = "2021",
abstract = "Objective: To evaluate an association between bone levels of inflammation/oxidative stress mediators and postoperative discomfort after third molar conventional or piezosurgery. Material and methods: Twenty-six subjects with bilaterally impacted mandibular third molars, who underwent either piezo or conventional surgery, were included in a split-mouth design study. MicroRNA-21 (miR-21) expression, interleukin-1 beta (IL-1β), and vascular endothelial growth factor (VEGF) proteins, as well as superoxide dismutase (SOD) activity in alveolar bone, were evaluated. Pain intensity, the first pain appearance, analgesic first use and total dose taken, trismus, and swelling were clinically recorded. Results: MiR-21 expression was higher while VEGF protein was lower in piezosurgery vs. conventional groups. The differences in IL-1β protein and SOD activity were not significant between groups. The pain intensity on the first day was significantly decreased in piezosurgery group. The first pain appearance and the first analgesic taken were reported sooner in conventional vs. piezosurgical group. Significantly pronounced trismus on the third day following conventional surgery was found. In conventional group, significantly increased trismus was observed on the third compared to the first postoperative day. MiR-21 showed significant correlation with the first pain appearance. Conclusion: Delayed onset of less pronounced postoperative pain after piezosurgical vs. conventional extraction of impacted lower third molar was significantly associated with expression of bone miR-21. Clinical relevance: Alveolar bone miR-21 may reflect surgical stress and is associated with third molar postoperative pain onset.",
journal = "Clinical Oral Investigations",
title = "Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort",
volume = "25",
number = "1",
pages = "319-328",
doi = "10.1007/s00784-020-03366-6"
}

Vučetić, M., Roganović, J., Freilich, M., Shafer, D., Milić, M., Đukić, L., Petrović, N., Marković, E., Marković, A.,& Brković, B.. (2021). Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort. in Clinical Oral Investigations, 25(1), 319-328.
https://doi.org/10.1007/s00784-020-03366-6

Vučetić M, Roganović J, Freilich M, Shafer D, Milić M, Đukić L, Petrović N, Marković E, Marković A, Brković B. Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort. in Clinical Oral Investigations. 2021;25(1):319-328.
doi:10.1007/s00784-020-03366-6 .

Vučetić, Milan, Roganović, Jelena, Freilich, M., Shafer, D., Milić, Marija, Đukić, Ljiljana, Petrović, Nina, Marković, Evgenija, Marković, Aleksa, Brković, Božidar, "Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort" in Clinical Oral Investigations, 25, no. 1 (2021):319-328,
https://doi.org/10.1007/s00784-020-03366-6 . .

TY  - JOUR
AU  - Biočanin, Vladimir
AU  - Antonijević, Đorđe
AU  - Poštić, Srđan D.
AU  - Ilić, Dragan V.
AU  - Vuković, Zorica M.
AU  - Milić, Marija S.
AU  - Fan, Yifang
AU  - Li, Zhiyu Y.
AU  - Brković, Božidar
AU  - Đurić, Marija
PY  - 2018
UR  - http://linkinghub.elsevier.com/retrieve/pii/S0099239917311226
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7740
AB  - Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ({[}10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.
T2  - Journal of Endodontics
T1  - Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin
VL  - 44
IS  - 5
SP  - 816
EP  - 821
DO  - 10.1016/j.joen.2017.09.022
ER  - 

@article{
author = "Biočanin, Vladimir and Antonijević, Đorđe and Poštić, Srđan D. and Ilić, Dragan V. and Vuković, Zorica M. and Milić, Marija S. and Fan, Yifang and Li, Zhiyu Y. and Brković, Božidar and Đurić, Marija",
year = "2018",
abstract = "Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ({[}10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.",
journal = "Journal of Endodontics",
title = "Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin",
volume = "44",
number = "5",
pages = "816-821",
doi = "10.1016/j.joen.2017.09.022"
}

Biočanin, V., Antonijević, Đ., Poštić, S. D., Ilić, D. V., Vuković, Z. M., Milić, M. S., Fan, Y., Li, Z. Y., Brković, B.,& Đurić, M.. (2018). Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin. in Journal of Endodontics, 44(5), 816-821.
https://doi.org/10.1016/j.joen.2017.09.022

Biočanin V, Antonijević Đ, Poštić SD, Ilić DV, Vuković ZM, Milić MS, Fan Y, Li ZY, Brković B, Đurić M. Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin. in Journal of Endodontics. 2018;44(5):816-821.
doi:10.1016/j.joen.2017.09.022 .

Biočanin, Vladimir, Antonijević, Đorđe, Poštić, Srđan D., Ilić, Dragan V., Vuković, Zorica M., Milić, Marija S., Fan, Yifang, Li, Zhiyu Y., Brković, Božidar, Đurić, Marija, "Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin" in Journal of Endodontics, 44, no. 5 (2018):816-821,
https://doi.org/10.1016/j.joen.2017.09.022 . .