Sladić, Dušan M.

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  • Sladić, Dušan M. (8)

Author's Bibliography

Novel 1,3,4-thiadiazole–chalcone hybrids containing catechol moiety: synthesis, antioxidant activity, cytotoxicity and DNA interaction studies

Jakovljević, Katarina; Joksović, Milan D.; Matić, Ivana Z.; Petrović, Nina; Stanojković, Tatjana P.; Sladić, Dušan M.; Vujčić, Miroslava T.; Janović, Barbara S.; Joksović, Ljubinka G.; Trifunović, Snežana; Marković, Violeta

(2018)

TY  - JOUR
AU  - Jakovljević, Katarina
AU  - Joksović, Milan D.
AU  - Matić, Ivana Z.
AU  - Petrović, Nina
AU  - Stanojković, Tatjana P.
AU  - Sladić, Dušan M.
AU  - Vujčić, Miroslava T.
AU  - Janović, Barbara S.
AU  - Joksović, Ljubinka G.
AU  - Trifunović, Snežana
AU  - Marković, Violeta
PY  - 2018
UR  - http://xlink.rsc.org/?DOI=C8MD00316E
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7928
AB  - Hybrid compounds that combine the 1,3,4-thiadiazole-containing catechol moiety with a chalcone motif were synthesized and examined for their antioxidant activity, cytotoxicity, and DNA-binding activity. A series of thirteen compounds showed strong antioxidant and cytotoxic effects on human acute promyelocytic leukemia HL-60 cells. Several compounds exerted good cytotoxic activities on cervical adenocarcinoma HeLa cells. The treatment of HeLa cells with IC50 and double IC50 concentrations of the compounds 5a, 5c, 5f, and 5m induced a statistically significant increase in the percentage of cells within a subG1 cell cycle phase. The examined compounds caused G2/M cell cycle arrest in HeLa cells. Each of these compounds triggered apoptosis in HeLa cells through activation of caspase-3, the main effector caspase, caspase-8, which is involved in the extrinsic apoptotic pathway, and caspase-9, which is involved in the intrinsic apoptotic pathway. All of the examined compounds decreased the expression levels of MMP2 in HeLa cells and levels of protumorigenic miR-133b. Compounds 5a and 5m lowered the expression level of oncogenic miR-21 in HeLa cells. In addition, compounds 5a, 5f, and 5m decreased the expression levels of oncogenic miR-155 while the treatment of HeLa cells with compounds 5a, 5c, and 5f increased expression of tumor-suppressive miR-206. Observed effects of these compounds on expression levels of four examined miRNAs suggest their prominent cancer-suppressive activity. An investigation by absorption and fluorescence spectroscopy showed more efficient calf thymus DNA binding activity of the compound 5m in comparison to other tested compounds. Results of a pUC19 plasmid cleavage study and comet assay showed DNA damaging activities of compounds 5a and 5c.
T2  - MedChemComm
T1  - Novel 1,3,4-thiadiazole–chalcone hybrids containing catechol moiety: synthesis, antioxidant activity, cytotoxicity and DNA interaction studies
VL  - 9
IS  - 10
SP  - 1679
EP  - 1697
DO  - 10.1039/C8MD00316E
ER  - 
@article{
author = "Jakovljević, Katarina and Joksović, Milan D. and Matić, Ivana Z. and Petrović, Nina and Stanojković, Tatjana P. and Sladić, Dušan M. and Vujčić, Miroslava T. and Janović, Barbara S. and Joksović, Ljubinka G. and Trifunović, Snežana and Marković, Violeta",
year = "2018",
abstract = "Hybrid compounds that combine the 1,3,4-thiadiazole-containing catechol moiety with a chalcone motif were synthesized and examined for their antioxidant activity, cytotoxicity, and DNA-binding activity. A series of thirteen compounds showed strong antioxidant and cytotoxic effects on human acute promyelocytic leukemia HL-60 cells. Several compounds exerted good cytotoxic activities on cervical adenocarcinoma HeLa cells. The treatment of HeLa cells with IC50 and double IC50 concentrations of the compounds 5a, 5c, 5f, and 5m induced a statistically significant increase in the percentage of cells within a subG1 cell cycle phase. The examined compounds caused G2/M cell cycle arrest in HeLa cells. Each of these compounds triggered apoptosis in HeLa cells through activation of caspase-3, the main effector caspase, caspase-8, which is involved in the extrinsic apoptotic pathway, and caspase-9, which is involved in the intrinsic apoptotic pathway. All of the examined compounds decreased the expression levels of MMP2 in HeLa cells and levels of protumorigenic miR-133b. Compounds 5a and 5m lowered the expression level of oncogenic miR-21 in HeLa cells. In addition, compounds 5a, 5f, and 5m decreased the expression levels of oncogenic miR-155 while the treatment of HeLa cells with compounds 5a, 5c, and 5f increased expression of tumor-suppressive miR-206. Observed effects of these compounds on expression levels of four examined miRNAs suggest their prominent cancer-suppressive activity. An investigation by absorption and fluorescence spectroscopy showed more efficient calf thymus DNA binding activity of the compound 5m in comparison to other tested compounds. Results of a pUC19 plasmid cleavage study and comet assay showed DNA damaging activities of compounds 5a and 5c.",
journal = "MedChemComm",
title = "Novel 1,3,4-thiadiazole–chalcone hybrids containing catechol moiety: synthesis, antioxidant activity, cytotoxicity and DNA interaction studies",
volume = "9",
number = "10",
pages = "1679-1697",
doi = "10.1039/C8MD00316E"
}
Jakovljević, K., Joksović, M. D., Matić, I. Z., Petrović, N., Stanojković, T. P., Sladić, D. M., Vujčić, M. T., Janović, B. S., Joksović, L. G., Trifunović, S.,& Marković, V.. (2018). Novel 1,3,4-thiadiazole–chalcone hybrids containing catechol moiety: synthesis, antioxidant activity, cytotoxicity and DNA interaction studies. in MedChemComm, 9(10), 1679-1697.
https://doi.org/10.1039/C8MD00316E
Jakovljević K, Joksović MD, Matić IZ, Petrović N, Stanojković TP, Sladić DM, Vujčić MT, Janović BS, Joksović LG, Trifunović S, Marković V. Novel 1,3,4-thiadiazole–chalcone hybrids containing catechol moiety: synthesis, antioxidant activity, cytotoxicity and DNA interaction studies. in MedChemComm. 2018;9(10):1679-1697.
doi:10.1039/C8MD00316E .
Jakovljević, Katarina, Joksović, Milan D., Matić, Ivana Z., Petrović, Nina, Stanojković, Tatjana P., Sladić, Dušan M., Vujčić, Miroslava T., Janović, Barbara S., Joksović, Ljubinka G., Trifunović, Snežana, Marković, Violeta, "Novel 1,3,4-thiadiazole–chalcone hybrids containing catechol moiety: synthesis, antioxidant activity, cytotoxicity and DNA interaction studies" in MedChemComm, 9, no. 10 (2018):1679-1697,
https://doi.org/10.1039/C8MD00316E . .
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Interactions of cytotoxic amino acid derivatives of tert-butylquinone with DNA and lysozyme

Vilipic, Jovana P.; Novaković, Irena T.; Zlatovic, Mario V.; Vujčić, Miroslava T.; Tufegdzic, Srdan J.; Sladić, Dušan M.

(2016)

TY  - JOUR
AU  - Vilipic, Jovana P.
AU  - Novaković, Irena T.
AU  - Zlatovic, Mario V.
AU  - Vujčić, Miroslava T.
AU  - Tufegdzic, Srdan J.
AU  - Sladić, Dušan M.
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1405
AB  - The interactions of nine amino acid derivatives of tert-butylquinone with biomacromolecules were studied. Sodium dodecyl sulphate (SDS) gel electrophoresis and mass spectrometry confirmed the absence of modifications of lysozyme by any of the synthesized compounds. Spectrophotometric studies demonstrated hyperchromism, i.e., the existence of interactions between the quinones and calf thymus DNA (CT-DNA). Determination of the binding constants by absorption titration indicated weak interactions between the quinone derivatives and CT-DNA. The quenching of fluorescence of the intercalator ethidium bromide (EB) from the EB-CT-DNA system and of the minor groove binder Hoechst 33258 (H) from the H-CT-DNA system by the synthesized derivatives indicated interactions of the compounds and CT-DNA. Circular dichroism (CD) spectra demonstrated a non-intercalative binding mode of the quinone derivatives to CT-DNA. Molecular docking results confirmed binding to the minor groove. The electrophoretic pattern showed no cleavage of the pUC19 plasmid in the presence of any of the synthesized compounds. The ability of the derivatives to scavenge radicals was confirmed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) test. All the presented results suggest that the DNA minor groove binding is the principal mechanism of action of the examined amino acid derivatives.
T2  - Journal of the Serbian Chemical Society
T1  - Interactions of cytotoxic amino acid derivatives of tert-butylquinone with DNA and lysozyme
VL  - 81
IS  - 12
SP  - 1345
EP  - 1358
DO  - 10.2298/JSC160725101V
ER  - 
@article{
author = "Vilipic, Jovana P. and Novaković, Irena T. and Zlatovic, Mario V. and Vujčić, Miroslava T. and Tufegdzic, Srdan J. and Sladić, Dušan M.",
year = "2016",
abstract = "The interactions of nine amino acid derivatives of tert-butylquinone with biomacromolecules were studied. Sodium dodecyl sulphate (SDS) gel electrophoresis and mass spectrometry confirmed the absence of modifications of lysozyme by any of the synthesized compounds. Spectrophotometric studies demonstrated hyperchromism, i.e., the existence of interactions between the quinones and calf thymus DNA (CT-DNA). Determination of the binding constants by absorption titration indicated weak interactions between the quinone derivatives and CT-DNA. The quenching of fluorescence of the intercalator ethidium bromide (EB) from the EB-CT-DNA system and of the minor groove binder Hoechst 33258 (H) from the H-CT-DNA system by the synthesized derivatives indicated interactions of the compounds and CT-DNA. Circular dichroism (CD) spectra demonstrated a non-intercalative binding mode of the quinone derivatives to CT-DNA. Molecular docking results confirmed binding to the minor groove. The electrophoretic pattern showed no cleavage of the pUC19 plasmid in the presence of any of the synthesized compounds. The ability of the derivatives to scavenge radicals was confirmed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) test. All the presented results suggest that the DNA minor groove binding is the principal mechanism of action of the examined amino acid derivatives.",
journal = "Journal of the Serbian Chemical Society",
title = "Interactions of cytotoxic amino acid derivatives of tert-butylquinone with DNA and lysozyme",
volume = "81",
number = "12",
pages = "1345-1358",
doi = "10.2298/JSC160725101V"
}
Vilipic, J. P., Novaković, I. T., Zlatovic, M. V., Vujčić, M. T., Tufegdzic, S. J.,& Sladić, D. M.. (2016). Interactions of cytotoxic amino acid derivatives of tert-butylquinone with DNA and lysozyme. in Journal of the Serbian Chemical Society, 81(12), 1345-1358.
https://doi.org/10.2298/JSC160725101V
Vilipic JP, Novaković IT, Zlatovic MV, Vujčić MT, Tufegdzic SJ, Sladić DM. Interactions of cytotoxic amino acid derivatives of tert-butylquinone with DNA and lysozyme. in Journal of the Serbian Chemical Society. 2016;81(12):1345-1358.
doi:10.2298/JSC160725101V .
Vilipic, Jovana P., Novaković, Irena T., Zlatovic, Mario V., Vujčić, Miroslava T., Tufegdzic, Srdan J., Sladić, Dušan M., "Interactions of cytotoxic amino acid derivatives of tert-butylquinone with DNA and lysozyme" in Journal of the Serbian Chemical Society, 81, no. 12 (2016):1345-1358,
https://doi.org/10.2298/JSC160725101V . .
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Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction

Filipović, Nenad R.; Bjelogrlić, Snežana; Marinković, Aleksandar D.; Verbić, Tatjana Z.; Cvijetić, Ilija N.; Senćanski, Milan V.; Rodić, Marko; Vujčić, Miroslava T.; Sladić, Dušan M.; Striković, Zlatko; Todorović, Tamara R.; Muller, Christian D.

(2015)

TY  - JOUR
AU  - Filipović, Nenad R.
AU  - Bjelogrlić, Snežana
AU  - Marinković, Aleksandar D.
AU  - Verbić, Tatjana Z.
AU  - Cvijetić, Ilija N.
AU  - Senćanski, Milan V.
AU  - Rodić, Marko
AU  - Vujčić, Miroslava T.
AU  - Sladić, Dušan M.
AU  - Striković, Zlatko
AU  - Todorović, Tamara R.
AU  - Muller, Christian D.
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/809
AB  - A new Zn(II)-based potential chemotherapeutic agent was synthesized from the ligand 2-quinolinecarboxaldehyde selenosemicarbazone (Hqasesc). Single crystal X-ray diffraction analysis showed that the Zn(II) complex consists of a cation [Zn(Hqasesc)(2)](2+), two perchlorate anions and one ethanol solvent molecule. The interaction of calf thymus (CT) DNA and human serum albumin (HSA) with the Zn(II) complex was explored using absorption and emission spectral methods, and also has been supported by molecular docking studies. The complex has more affinity to minor DNA groove than major, with no significant intercalation. The HSA interaction studies of the complex revealed the quenching of the intrinsic fluorescence of the HSA through a static quenching mechanism. The antitumor activity of the ligand and the complex against pancreatic adenocarcinoma cell line (AsPC-1) and acute monocytic leukemia (THP-1) cells was evaluated. Both compounds are strong concentration-dependent apoptosis inducers in THP-1 cells. While Hqasesc in AsPC-1 cells induces apoptosis only at the highest concentration, treatment with the Zn complex shows a concentration-dependent apoptotic response, where the treated cells are arrested in the G1-to-S phase accompanied with extensive activation of caspase-8 and -9. These results indicate that the ligand and Zn(II) complex display cell phenotype specific activity.
T2  - RSC Advances
T1  - Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction
VL  - 5
IS  - 115
SP  - 95191
EP  - 95211
DO  - 10.1039/c5ra19849f
ER  - 
@article{
author = "Filipović, Nenad R. and Bjelogrlić, Snežana and Marinković, Aleksandar D. and Verbić, Tatjana Z. and Cvijetić, Ilija N. and Senćanski, Milan V. and Rodić, Marko and Vujčić, Miroslava T. and Sladić, Dušan M. and Striković, Zlatko and Todorović, Tamara R. and Muller, Christian D.",
year = "2015",
abstract = "A new Zn(II)-based potential chemotherapeutic agent was synthesized from the ligand 2-quinolinecarboxaldehyde selenosemicarbazone (Hqasesc). Single crystal X-ray diffraction analysis showed that the Zn(II) complex consists of a cation [Zn(Hqasesc)(2)](2+), two perchlorate anions and one ethanol solvent molecule. The interaction of calf thymus (CT) DNA and human serum albumin (HSA) with the Zn(II) complex was explored using absorption and emission spectral methods, and also has been supported by molecular docking studies. The complex has more affinity to minor DNA groove than major, with no significant intercalation. The HSA interaction studies of the complex revealed the quenching of the intrinsic fluorescence of the HSA through a static quenching mechanism. The antitumor activity of the ligand and the complex against pancreatic adenocarcinoma cell line (AsPC-1) and acute monocytic leukemia (THP-1) cells was evaluated. Both compounds are strong concentration-dependent apoptosis inducers in THP-1 cells. While Hqasesc in AsPC-1 cells induces apoptosis only at the highest concentration, treatment with the Zn complex shows a concentration-dependent apoptotic response, where the treated cells are arrested in the G1-to-S phase accompanied with extensive activation of caspase-8 and -9. These results indicate that the ligand and Zn(II) complex display cell phenotype specific activity.",
journal = "RSC Advances",
title = "Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction",
volume = "5",
number = "115",
pages = "95191-95211",
doi = "10.1039/c5ra19849f"
}
Filipović, N. R., Bjelogrlić, S., Marinković, A. D., Verbić, T. Z., Cvijetić, I. N., Senćanski, M. V., Rodić, M., Vujčić, M. T., Sladić, D. M., Striković, Z., Todorović, T. R.,& Muller, C. D.. (2015). Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction. in RSC Advances, 5(115), 95191-95211.
https://doi.org/10.1039/c5ra19849f
Filipović NR, Bjelogrlić S, Marinković AD, Verbić TZ, Cvijetić IN, Senćanski MV, Rodić M, Vujčić MT, Sladić DM, Striković Z, Todorović TR, Muller CD. Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction. in RSC Advances. 2015;5(115):95191-95211.
doi:10.1039/c5ra19849f .
Filipović, Nenad R., Bjelogrlić, Snežana, Marinković, Aleksandar D., Verbić, Tatjana Z., Cvijetić, Ilija N., Senćanski, Milan V., Rodić, Marko, Vujčić, Miroslava T., Sladić, Dušan M., Striković, Zlatko, Todorović, Tamara R., Muller, Christian D., "Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction" in RSC Advances, 5, no. 115 (2015):95191-95211,
https://doi.org/10.1039/c5ra19849f . .
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Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate

Milenković, Milica; Cantoni, Giulia; Bacchi, Alessia; Spasojević, Vojislav; Milenković, Marina; Sladić, Dušan M.; Krstić, Natalija; Anđelković, Katarina

(2014)

TY  - JOUR
AU  - Milenković, Milica
AU  - Cantoni, Giulia
AU  - Bacchi, Alessia
AU  - Spasojević, Vojislav
AU  - Milenković, Marina
AU  - Sladić, Dušan M.
AU  - Krstić, Natalija
AU  - Anđelković, Katarina
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/99
AB  - Complexes of Pd(II) and Fe(III) with the condensation derivative of 2-(diphenylphosphino)benzaldehyde and ethyl carbazate were synthesized, characterized, and their antimicrobial activity was evaluated. The structures of the Pd(II) and Fe(III) complexes in solid state were determined by IR, elemental analysis and X-ray analysis. The structure of Pd(II) complex in solution was determined by NMR spectroscopy. Results of magnetic measurements for Fe(III) complex were reported. In both complexes the ligand is coordinated as tridentate via the phosphorus, the imine nitrogen and the carbonyl oxygen atoms. Results of antimicrobial activity investigation indicate that the activity of the ligand is enhanced upon complexation, and that the MIC values of the iron complex to some bacterial strains are not much higher than those of cefotaxime. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Polyhedron
T1  - Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate
VL  - 80
IS  - SI
SP  - 47
EP  - 52
DO  - 10.1016/j.poly.2014.01.022
ER  - 
@article{
author = "Milenković, Milica and Cantoni, Giulia and Bacchi, Alessia and Spasojević, Vojislav and Milenković, Marina and Sladić, Dušan M. and Krstić, Natalija and Anđelković, Katarina",
year = "2014",
abstract = "Complexes of Pd(II) and Fe(III) with the condensation derivative of 2-(diphenylphosphino)benzaldehyde and ethyl carbazate were synthesized, characterized, and their antimicrobial activity was evaluated. The structures of the Pd(II) and Fe(III) complexes in solid state were determined by IR, elemental analysis and X-ray analysis. The structure of Pd(II) complex in solution was determined by NMR spectroscopy. Results of magnetic measurements for Fe(III) complex were reported. In both complexes the ligand is coordinated as tridentate via the phosphorus, the imine nitrogen and the carbonyl oxygen atoms. Results of antimicrobial activity investigation indicate that the activity of the ligand is enhanced upon complexation, and that the MIC values of the iron complex to some bacterial strains are not much higher than those of cefotaxime. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Polyhedron",
title = "Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate",
volume = "80",
number = "SI",
pages = "47-52",
doi = "10.1016/j.poly.2014.01.022"
}
Milenković, M., Cantoni, G., Bacchi, A., Spasojević, V., Milenković, M., Sladić, D. M., Krstić, N.,& Anđelković, K.. (2014). Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate. in Polyhedron, 80(SI), 47-52.
https://doi.org/10.1016/j.poly.2014.01.022
Milenković M, Cantoni G, Bacchi A, Spasojević V, Milenković M, Sladić DM, Krstić N, Anđelković K. Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate. in Polyhedron. 2014;80(SI):47-52.
doi:10.1016/j.poly.2014.01.022 .
Milenković, Milica, Cantoni, Giulia, Bacchi, Alessia, Spasojević, Vojislav, Milenković, Marina, Sladić, Dušan M., Krstić, Natalija, Anđelković, Katarina, "Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate" in Polyhedron, 80, no. SI (2014):47-52,
https://doi.org/10.1016/j.poly.2014.01.022 . .
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Analysis of the structures of the Cu(I) and Cu(II) complexes with 3-acetylpyridine and thiocyanate

Cobeljic, Bozidar; Pevec, Andrej; Turel, Iztok; Spasojević, Vojislav; Milčić, Miloš K.; Mitić, Dragana; Sladić, Dušan M.; Anđelković, Katarina

(2014)

TY  - JOUR
AU  - Cobeljic, Bozidar
AU  - Pevec, Andrej
AU  - Turel, Iztok
AU  - Spasojević, Vojislav
AU  - Milčić, Miloš K.
AU  - Mitić, Dragana
AU  - Sladić, Dušan M.
AU  - Anđelković, Katarina
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5887
AB  - 3-Acetylpyridine thiosemicarbazone hydrochloride was synthesized and structurally characterized. Complexes of Cu(II) with this ligand could not be obtained by direct synthesis. By synthesis in situ mixing Cu(BF4)(2)center dot 6H(2)O, 3-acetylpyridine (3-Acpy) and semicarbazide, a Cu(I) polymer, {[Cu(SCN)(3-Acpy)(2)]}(n) was obtained and structurally characterized. Reaction of Cu(BF4)(2)center dot 6H(2)O, 3-acetylpyridine and ammonium thiocyanate afforded a dinuclear Cu(II) complex with two thiocyanate ions in bridges, which was structurally characterized. Magnetic measurements were performed for the dinuclear complex. OFT calculations provided explanation for inability to obtain a mononuclear complex. (C) 2013 Elsevier Ltd. All rights reserved.
T2  - Polyhedron
T1  - Analysis of the structures of the Cu(I) and Cu(II) complexes with 3-acetylpyridine and thiocyanate
VL  - 69
SP  - 77
EP  - 83
DO  - 10.1016/j.poly.2013.11.027
ER  - 
@article{
author = "Cobeljic, Bozidar and Pevec, Andrej and Turel, Iztok and Spasojević, Vojislav and Milčić, Miloš K. and Mitić, Dragana and Sladić, Dušan M. and Anđelković, Katarina",
year = "2014",
abstract = "3-Acetylpyridine thiosemicarbazone hydrochloride was synthesized and structurally characterized. Complexes of Cu(II) with this ligand could not be obtained by direct synthesis. By synthesis in situ mixing Cu(BF4)(2)center dot 6H(2)O, 3-acetylpyridine (3-Acpy) and semicarbazide, a Cu(I) polymer, {[Cu(SCN)(3-Acpy)(2)]}(n) was obtained and structurally characterized. Reaction of Cu(BF4)(2)center dot 6H(2)O, 3-acetylpyridine and ammonium thiocyanate afforded a dinuclear Cu(II) complex with two thiocyanate ions in bridges, which was structurally characterized. Magnetic measurements were performed for the dinuclear complex. OFT calculations provided explanation for inability to obtain a mononuclear complex. (C) 2013 Elsevier Ltd. All rights reserved.",
journal = "Polyhedron",
title = "Analysis of the structures of the Cu(I) and Cu(II) complexes with 3-acetylpyridine and thiocyanate",
volume = "69",
pages = "77-83",
doi = "10.1016/j.poly.2013.11.027"
}
Cobeljic, B., Pevec, A., Turel, I., Spasojević, V., Milčić, M. K., Mitić, D., Sladić, D. M.,& Anđelković, K.. (2014). Analysis of the structures of the Cu(I) and Cu(II) complexes with 3-acetylpyridine and thiocyanate. in Polyhedron, 69, 77-83.
https://doi.org/10.1016/j.poly.2013.11.027
Cobeljic B, Pevec A, Turel I, Spasojević V, Milčić MK, Mitić D, Sladić DM, Anđelković K. Analysis of the structures of the Cu(I) and Cu(II) complexes with 3-acetylpyridine and thiocyanate. in Polyhedron. 2014;69:77-83.
doi:10.1016/j.poly.2013.11.027 .
Cobeljic, Bozidar, Pevec, Andrej, Turel, Iztok, Spasojević, Vojislav, Milčić, Miloš K., Mitić, Dragana, Sladić, Dušan M., Anđelković, Katarina, "Analysis of the structures of the Cu(I) and Cu(II) complexes with 3-acetylpyridine and thiocyanate" in Polyhedron, 69 (2014):77-83,
https://doi.org/10.1016/j.poly.2013.11.027 . .
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Synthesis and structure of a Ni(II) complex with N ,N (2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate

Cobeljic, Bozidar; Warzajtis, Beata; Rychlewska, Urszula; Radanovic, Dusanka; Spasojević, Vojislav; Sladić, Dušan M.; Eshkourfu, Rabia; Anđelković, Katarina

(2012)

TY  - JOUR
AU  - Cobeljic, Bozidar
AU  - Warzajtis, Beata
AU  - Rychlewska, Urszula
AU  - Radanovic, Dusanka
AU  - Spasojević, Vojislav
AU  - Sladić, Dušan M.
AU  - Eshkourfu, Rabia
AU  - Anđelković, Katarina
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4762
AB  - A new malonic dihydrazide-based ligand, N,N(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide (H(2)L3), has been prepared and characterized by elemental analysis, IR, C-13 NMR, and H-1 NMR spectroscopies. In the reaction of H(2)L3 with Ni(II) a binuclear complex has been obtained. The structure of the complex was established by X-ray analysis. Each Ni(II) is coordinated with two NNO donor sets from two ligand molecules in dianionic form (L3(2-)) forming an octahedral geometry. Multiple intramolecular C-H center dot center dot center dot pi (chelate ring) interactions support the molecular geometry of the [Ni-2(L3)(2)] complex. The structure of [Ni-2(L3)(2)] is compared with those of analogous Ni(II) complexes with pyridine dihydrazone type ligands. Magnetic behavior of the dinuclear complex was studied in temperature range of 2-300 K.
T2  - Journal of Coordination Chemistry
T1  - Synthesis and structure of a Ni(II) complex with N ,N (2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate
VL  - 65
IS  - 4
SP  - 655
EP  - 667
DO  - 10.1080/00958972.2012.658778
ER  - 
@article{
author = "Cobeljic, Bozidar and Warzajtis, Beata and Rychlewska, Urszula and Radanovic, Dusanka and Spasojević, Vojislav and Sladić, Dušan M. and Eshkourfu, Rabia and Anđelković, Katarina",
year = "2012",
abstract = "A new malonic dihydrazide-based ligand, N,N(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide (H(2)L3), has been prepared and characterized by elemental analysis, IR, C-13 NMR, and H-1 NMR spectroscopies. In the reaction of H(2)L3 with Ni(II) a binuclear complex has been obtained. The structure of the complex was established by X-ray analysis. Each Ni(II) is coordinated with two NNO donor sets from two ligand molecules in dianionic form (L3(2-)) forming an octahedral geometry. Multiple intramolecular C-H center dot center dot center dot pi (chelate ring) interactions support the molecular geometry of the [Ni-2(L3)(2)] complex. The structure of [Ni-2(L3)(2)] is compared with those of analogous Ni(II) complexes with pyridine dihydrazone type ligands. Magnetic behavior of the dinuclear complex was studied in temperature range of 2-300 K.",
journal = "Journal of Coordination Chemistry",
title = "Synthesis and structure of a Ni(II) complex with N ,N (2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate",
volume = "65",
number = "4",
pages = "655-667",
doi = "10.1080/00958972.2012.658778"
}
Cobeljic, B., Warzajtis, B., Rychlewska, U., Radanovic, D., Spasojević, V., Sladić, D. M., Eshkourfu, R.,& Anđelković, K.. (2012). Synthesis and structure of a Ni(II) complex with N ,N (2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate. in Journal of Coordination Chemistry, 65(4), 655-667.
https://doi.org/10.1080/00958972.2012.658778
Cobeljic B, Warzajtis B, Rychlewska U, Radanovic D, Spasojević V, Sladić DM, Eshkourfu R, Anđelković K. Synthesis and structure of a Ni(II) complex with N ,N (2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate. in Journal of Coordination Chemistry. 2012;65(4):655-667.
doi:10.1080/00958972.2012.658778 .
Cobeljic, Bozidar, Warzajtis, Beata, Rychlewska, Urszula, Radanovic, Dusanka, Spasojević, Vojislav, Sladić, Dušan M., Eshkourfu, Rabia, Anđelković, Katarina, "Synthesis and structure of a Ni(II) complex with N ,N (2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate" in Journal of Coordination Chemistry, 65, no. 4 (2012):655-667,
https://doi.org/10.1080/00958972.2012.658778 . .
5
4
5

Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity

Filipović, Nenad R.; Borrmann, Horst; Todorović, Tamara; Borna, Marija; Spasojević, Vojislav; Sladić, Dušan M.; Novaković, Irena T.; Anđelković, Katarina

(2009)

TY  - JOUR
AU  - Filipović, Nenad R.
AU  - Borrmann, Horst
AU  - Todorović, Tamara
AU  - Borna, Marija
AU  - Spasojević, Vojislav
AU  - Sladić, Dušan M.
AU  - Novaković, Irena T.
AU  - Anđelković, Katarina
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3680
AB  - Three novel copper(II) complexes as condensation derivatives of 2-pyridinecarboxaldehyde, 2-acetylpyridine or 2-quinolinecarboxaldehyde with ethyl hydrazinoacetate hydrochloride were synthesized. X-ray crystal structures of all three complexes were determined. Crystallographic data indicate a common basis of the structures with some major differences. Both pyridine derivatives form complexes of the type [CuCl(2)L] with distorted square-planar geometry around copper(II), but show a decisive difference in the side chain orientation. The quinoline derivative forms a dimeric complex of type [Cu(2)Cl(4)L(2)] with distorted trigonal bipyramidal geometry around copper(II), but a rather short Cu center dot center dot center dot Cu contact, which is reflected in its magnetic properties. All three complexes showed antibacterial activity. (c) 2008 Elsevier B.V. All rights reserved.
T2  - Inorganica Chimica Acta
T1  - Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity
VL  - 362
IS  - 6
SP  - 1996
EP  - 2000
DO  - 10.1016/j.ica.2008.09.019
ER  - 
@article{
author = "Filipović, Nenad R. and Borrmann, Horst and Todorović, Tamara and Borna, Marija and Spasojević, Vojislav and Sladić, Dušan M. and Novaković, Irena T. and Anđelković, Katarina",
year = "2009",
abstract = "Three novel copper(II) complexes as condensation derivatives of 2-pyridinecarboxaldehyde, 2-acetylpyridine or 2-quinolinecarboxaldehyde with ethyl hydrazinoacetate hydrochloride were synthesized. X-ray crystal structures of all three complexes were determined. Crystallographic data indicate a common basis of the structures with some major differences. Both pyridine derivatives form complexes of the type [CuCl(2)L] with distorted square-planar geometry around copper(II), but show a decisive difference in the side chain orientation. The quinoline derivative forms a dimeric complex of type [Cu(2)Cl(4)L(2)] with distorted trigonal bipyramidal geometry around copper(II), but a rather short Cu center dot center dot center dot Cu contact, which is reflected in its magnetic properties. All three complexes showed antibacterial activity. (c) 2008 Elsevier B.V. All rights reserved.",
journal = "Inorganica Chimica Acta",
title = "Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity",
volume = "362",
number = "6",
pages = "1996-2000",
doi = "10.1016/j.ica.2008.09.019"
}
Filipović, N. R., Borrmann, H., Todorović, T., Borna, M., Spasojević, V., Sladić, D. M., Novaković, I. T.,& Anđelković, K.. (2009). Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity. in Inorganica Chimica Acta, 362(6), 1996-2000.
https://doi.org/10.1016/j.ica.2008.09.019
Filipović NR, Borrmann H, Todorović T, Borna M, Spasojević V, Sladić DM, Novaković IT, Anđelković K. Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity. in Inorganica Chimica Acta. 2009;362(6):1996-2000.
doi:10.1016/j.ica.2008.09.019 .
Filipović, Nenad R., Borrmann, Horst, Todorović, Tamara, Borna, Marija, Spasojević, Vojislav, Sladić, Dušan M., Novaković, Irena T., Anđelković, Katarina, "Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity" in Inorganica Chimica Acta, 362, no. 6 (2009):1996-2000,
https://doi.org/10.1016/j.ica.2008.09.019 . .
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Preparation, crystal structure and antibacterial activity of condensation products of usnic acid and acyl hydrazides

Sladić, Dušan M.; Beljanski, Vladimir; Prelesnik, Bogdan V.; Bogdanović, Goran A.; Ivanović, Ivana; Anđelković, Katarina

(1998)

TY  - JOUR
AU  - Sladić, Dušan M.
AU  - Beljanski, Vladimir
AU  - Prelesnik, Bogdan V.
AU  - Bogdanović, Goran A.
AU  - Ivanović, Ivana
AU  - Anđelković, Katarina
PY  - 1998
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/43
AB  - Three condensation products of usnic acid with the hydrazides of alpha-naphthoic, caprylic, and oxamic acids, respectively, have been prepared and characterized by spectrometric methods. A reassignment of the C-13-NMR spectral data of usnic acid has been done. The crystal structure of usnic acid 11-[(1-naphthoyl)hydrazone] ethanol solvate (1:1) has been determined. This substance crystallizes in the monoclinic crystal system, the space group P2(1), with the unit cell dimensiones a=7.7365(7) Angstrom, b = 19.632(2) Angstrom, c = 9.4150(15) Angstrom, beta = 108.830(11)degrees, V = 1405.0(4) Angstrom(3), and Z=2. At the end of the structure analysis R = 0.055, R-w = 0.052 and S = 0.89. The antibacterial activities of the compounds have been evaluated. The greatest activity against Staphylococcus aureus was found for usnic acid, somewhat lower for the derivatives with hydrazides of alpha-naphthoic and caprylic acid, and much lower for the derivative with semioxamazide. The activities of these compounds probably depend on their lipophilicity.
T2  - Journal of the Serbian Chemical Society
T1  - Preparation, crystal structure and antibacterial activity of condensation products of usnic acid and acyl hydrazides
VL  - 63
IS  - 3
SP  - 171
EP  - 182
ER  - 
@article{
author = "Sladić, Dušan M. and Beljanski, Vladimir and Prelesnik, Bogdan V. and Bogdanović, Goran A. and Ivanović, Ivana and Anđelković, Katarina",
year = "1998",
abstract = "Three condensation products of usnic acid with the hydrazides of alpha-naphthoic, caprylic, and oxamic acids, respectively, have been prepared and characterized by spectrometric methods. A reassignment of the C-13-NMR spectral data of usnic acid has been done. The crystal structure of usnic acid 11-[(1-naphthoyl)hydrazone] ethanol solvate (1:1) has been determined. This substance crystallizes in the monoclinic crystal system, the space group P2(1), with the unit cell dimensiones a=7.7365(7) Angstrom, b = 19.632(2) Angstrom, c = 9.4150(15) Angstrom, beta = 108.830(11)degrees, V = 1405.0(4) Angstrom(3), and Z=2. At the end of the structure analysis R = 0.055, R-w = 0.052 and S = 0.89. The antibacterial activities of the compounds have been evaluated. The greatest activity against Staphylococcus aureus was found for usnic acid, somewhat lower for the derivatives with hydrazides of alpha-naphthoic and caprylic acid, and much lower for the derivative with semioxamazide. The activities of these compounds probably depend on their lipophilicity.",
journal = "Journal of the Serbian Chemical Society",
title = "Preparation, crystal structure and antibacterial activity of condensation products of usnic acid and acyl hydrazides",
volume = "63",
number = "3",
pages = "171-182"
}
Sladić, D. M., Beljanski, V., Prelesnik, B. V., Bogdanović, G. A., Ivanović, I.,& Anđelković, K.. (1998). Preparation, crystal structure and antibacterial activity of condensation products of usnic acid and acyl hydrazides. in Journal of the Serbian Chemical Society, 63(3), 171-182.
Sladić DM, Beljanski V, Prelesnik BV, Bogdanović GA, Ivanović I, Anđelković K. Preparation, crystal structure and antibacterial activity of condensation products of usnic acid and acyl hydrazides. in Journal of the Serbian Chemical Society. 1998;63(3):171-182..
Sladić, Dušan M., Beljanski, Vladimir, Prelesnik, Bogdan V., Bogdanović, Goran A., Ivanović, Ivana, Anđelković, Katarina, "Preparation, crystal structure and antibacterial activity of condensation products of usnic acid and acyl hydrazides" in Journal of the Serbian Chemical Society, 63, no. 3 (1998):171-182.
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