TY  - JOUR
AU  - Budimir, Milica
AU  - Jijie, Roxana
AU  - Ye, Ran
AU  - Barras, Alexandre
AU  - Melinte, Sorin
AU  - Silhanek, Alejandro
AU  - Marković, Zoran M.
AU  - Szunerits, Sabine
AU  - Boukherroub, Rabah
PY  - 2019
UR  - http://xlink.rsc.org/?DOI=C8TB01676C
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8181
AB  - Bacterial infections are one of the leading causes of disease worldwide. Conventional antibiotics are becoming less efficient, due to antibiotic-resistant bacterial strains. Therefore, the development of novel antibacterial materials and advanced treatment strategies are becoming increasingly important. In the present work, we developed a simple and efficient strategy for effective bacterial capture and their subsequent eradication through photothermal killing. The developed device consists of a flexible nanoheater, comprising a Kapton/Au nanoholes substrate, coated with reduced graphene oxide-polyethyleneimine (K/Au NH/rGO-PEI) thin films. The Au NH plasmonic structure was tailored to feature strong absorption in the near-infrared (NIR) region, where most biological matter has limited absorption, while PEI was investigated for its strong binding with bacteria through electrostatic interactions. The K/Au NH/rGO-PEI device was demonstrated to capture and eliminate effectively both planktonic Gram-positive Staphilococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli) bacteria after 10 min of NIR (980 nm) irradiation and, to destroy and eradicate Staphilococcus epidermidis (S. epidermidis) biofilms after 30 min irradiation. The technique developed herein is simple and universal with potential applications for eradication of different micro-organisms.
T2  - Journal of Materials Chemistry B
T1  - Efficient capture and photothermal ablation of planktonic bacteria and biofilms using reduced graphene oxide–polyethyleneimine flexible nanoheaters
VL  - 7
IS  - 17
SP  - 2771
EP  - 2781
DO  - 10.1039/C8TB01676C
ER  - 

@article{
author = "Budimir, Milica and Jijie, Roxana and Ye, Ran and Barras, Alexandre and Melinte, Sorin and Silhanek, Alejandro and Marković, Zoran M. and Szunerits, Sabine and Boukherroub, Rabah",
year = "2019",
abstract = "Bacterial infections are one of the leading causes of disease worldwide. Conventional antibiotics are becoming less efficient, due to antibiotic-resistant bacterial strains. Therefore, the development of novel antibacterial materials and advanced treatment strategies are becoming increasingly important. In the present work, we developed a simple and efficient strategy for effective bacterial capture and their subsequent eradication through photothermal killing. The developed device consists of a flexible nanoheater, comprising a Kapton/Au nanoholes substrate, coated with reduced graphene oxide-polyethyleneimine (K/Au NH/rGO-PEI) thin films. The Au NH plasmonic structure was tailored to feature strong absorption in the near-infrared (NIR) region, where most biological matter has limited absorption, while PEI was investigated for its strong binding with bacteria through electrostatic interactions. The K/Au NH/rGO-PEI device was demonstrated to capture and eliminate effectively both planktonic Gram-positive Staphilococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli) bacteria after 10 min of NIR (980 nm) irradiation and, to destroy and eradicate Staphilococcus epidermidis (S. epidermidis) biofilms after 30 min irradiation. The technique developed herein is simple and universal with potential applications for eradication of different micro-organisms.",
journal = "Journal of Materials Chemistry B",
title = "Efficient capture and photothermal ablation of planktonic bacteria and biofilms using reduced graphene oxide–polyethyleneimine flexible nanoheaters",
volume = "7",
number = "17",
pages = "2771-2781",
doi = "10.1039/C8TB01676C"
}

Budimir, M., Jijie, R., Ye, R., Barras, A., Melinte, S., Silhanek, A., Marković, Z. M., Szunerits, S.,& Boukherroub, R.. (2019). Efficient capture and photothermal ablation of planktonic bacteria and biofilms using reduced graphene oxide–polyethyleneimine flexible nanoheaters. in Journal of Materials Chemistry B, 7(17), 2771-2781.
https://doi.org/10.1039/C8TB01676C

Budimir M, Jijie R, Ye R, Barras A, Melinte S, Silhanek A, Marković ZM, Szunerits S, Boukherroub R. Efficient capture and photothermal ablation of planktonic bacteria and biofilms using reduced graphene oxide–polyethyleneimine flexible nanoheaters. in Journal of Materials Chemistry B. 2019;7(17):2771-2781.
doi:10.1039/C8TB01676C .

Budimir, Milica, Jijie, Roxana, Ye, Ran, Barras, Alexandre, Melinte, Sorin, Silhanek, Alejandro, Marković, Zoran M., Szunerits, Sabine, Boukherroub, Rabah, "Efficient capture and photothermal ablation of planktonic bacteria and biofilms using reduced graphene oxide–polyethyleneimine flexible nanoheaters" in Journal of Materials Chemistry B, 7, no. 17 (2019):2771-2781,
https://doi.org/10.1039/C8TB01676C . .