TY  - JOUR
AU  - Stojković, Ljiljana S.
AU  - Đurić, Tamara
AU  - Stanković, Aleksandra
AU  - Dinčić, Evica
AU  - Stančić, Olja
AU  - Veljković, Nevena V.
AU  - Alavantić, Dragan
AU  - Živković, Maja
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4841
AB  - We investigated the association of CX3CR1 genotypes/haplotypes with MS and performed the prediction analysis of protein sequence variants effects on CX3CL1/CX3CR1 interaction. We found no association of CX3CR1 with MS susceptibility. Frequency of I249T280 haplotype was significantly lower in SP compared to RR patients (RR GT 10 years, OR=0.30, 95%CI=0.11-0.79, p=0.01: OR=0.53, 95%CI=0.18-1.56, p=0.2, in sP LT 10 years vs. RR GT 10 years). Prediction analysis showed that I249 T280 protein variant would significantly affect CX3CL1/CX3CR1 interaction. Our results suggest that CX3CR1 I249T280 haplotype could have protective effect for switch to SP MS. Further research is warranted to validate and replicate currently observed results. (C) 2012 Elsevier B.V. All rights reserved.
T2  - Journal of Neuroimmunology
T1  - The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis
VL  - 245
IS  - 1-2
SP  - 87
EP  - 92
DO  - 10.1016/j.jneuroim.2011.12.028
ER  - 

@article{
author = "Stojković, Ljiljana S. and Đurić, Tamara and Stanković, Aleksandra and Dinčić, Evica and Stančić, Olja and Veljković, Nevena V. and Alavantić, Dragan and Živković, Maja",
year = "2012",
abstract = "We investigated the association of CX3CR1 genotypes/haplotypes with MS and performed the prediction analysis of protein sequence variants effects on CX3CL1/CX3CR1 interaction. We found no association of CX3CR1 with MS susceptibility. Frequency of I249T280 haplotype was significantly lower in SP compared to RR patients (RR GT 10 years, OR=0.30, 95%CI=0.11-0.79, p=0.01: OR=0.53, 95%CI=0.18-1.56, p=0.2, in sP LT 10 years vs. RR GT 10 years). Prediction analysis showed that I249 T280 protein variant would significantly affect CX3CL1/CX3CR1 interaction. Our results suggest that CX3CR1 I249T280 haplotype could have protective effect for switch to SP MS. Further research is warranted to validate and replicate currently observed results. (C) 2012 Elsevier B.V. All rights reserved.",
journal = "Journal of Neuroimmunology",
title = "The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis",
volume = "245",
number = "1-2",
pages = "87-92",
doi = "10.1016/j.jneuroim.2011.12.028"
}

Stojković, L. S., Đurić, T., Stanković, A., Dinčić, E., Stančić, O., Veljković, N. V., Alavantić, D.,& Živković, M.. (2012). The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis. in Journal of Neuroimmunology, 245(1-2), 87-92.
https://doi.org/10.1016/j.jneuroim.2011.12.028

Stojković LS, Đurić T, Stanković A, Dinčić E, Stančić O, Veljković NV, Alavantić D, Živković M. The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis. in Journal of Neuroimmunology. 2012;245(1-2):87-92.
doi:10.1016/j.jneuroim.2011.12.028 .

Stojković, Ljiljana S., Đurić, Tamara, Stanković, Aleksandra, Dinčić, Evica, Stančić, Olja, Veljković, Nevena V., Alavantić, Dragan, Živković, Maja, "The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis" in Journal of Neuroimmunology, 245, no. 1-2 (2012):87-92,
https://doi.org/10.1016/j.jneuroim.2011.12.028 . .