Mutavdžić, Dragosav R.

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  • Mutavdžić, Dragosav R. (2)
  • Mutavdžić, Dragosav (1)

Author's Bibliography

Cell wall response to UV radiation in needles of Picea omorika

Mitrović, Aleksandra Lj.; Simonović-Radosavljević, Jasna; Prokopijević, Miloš; Spasojević, Dragica; Kovačević, Jovana; Prodanović, Olivera; Todorović, Bratislav; Matović, Branko; Stanković, Mira; Maksimović, Vuk; Mutavdžić, Dragosav; Skočić, Miloš; Pešić, Mirjana; Prokić, Ljiljana; Radotić, Ksenija

(2021)

TY  - JOUR
AU  - Mitrović, Aleksandra Lj.
AU  - Simonović-Radosavljević, Jasna
AU  - Prokopijević, Miloš
AU  - Spasojević, Dragica
AU  - Kovačević, Jovana
AU  - Prodanović, Olivera
AU  - Todorović, Bratislav
AU  - Matović, Branko
AU  - Stanković, Mira
AU  - Maksimović, Vuk
AU  - Mutavdžić, Dragosav
AU  - Skočić, Miloš
AU  - Pešić, Mirjana
AU  - Prokić, Ljiljana
AU  - Radotić, Ksenija
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9129
AB  - The UV-B represents the minor fraction of the solar spectrum, while UV-C is not contained in natural solar radiation, but both radiation types can cause damaging effects in plants. Cell walls (CWs) are one of the targets for external stressors. Juvenile P. omorika trees were treated either with 21 day-high doses UV-B or with 7 day- UV-C in open-top chambers. Using spectroscopic and biochemical techniques, it was shown that the response to UV radiation includes numerous modifications in needle CW structure: relative content of xylan, xyloglucan, lignin and cellulose decreased; cellulose crystallinity changed; yield of lignin monomers with stronger connection of C[dbnd]C in side chain with the ring increased; re-distribution of inter- and intra-polymer H-bonds occurred. The recovery was mediated by an increase in the activities and changes in isoform profiles of CW bound covalent peroxidases (POD) and polyphenol oxidases (PO) (UV–B), and ionic POD and covalent PO (UV–C). A connection between activities of specific POD/PO isoforms and phenolic species (m- and p-coumaric acid, pinoresinol and cinnamic acid derivatives) was demonstrated, and supported by changes in the sRNA profile. In vivo fluorometry showed phenolics accumulation in needle epidermal CWs. These results imply transversal connections between polymers and changed mechanical properties of needle CW as a response to UV. The CW alterations enabled maintenance of physiological functions, as indicated by the preserved chlorophyll content and/or organization. The current study provides evidence that in conifers, needle CW response to both UV-B and UV-C includes biochemical modifications and structural remodeling. © 2021 Elsevier Masson SAS
T2  - Plant Physiology and Biochemistry
T1  - Cell wall response to UV radiation in needles of Picea omorika
VL  - 161
SP  - 176
EP  - 190
DO  - 10.1016/j.plaphy.2021.02.007
ER  - 
@article{
author = "Mitrović, Aleksandra Lj. and Simonović-Radosavljević, Jasna and Prokopijević, Miloš and Spasojević, Dragica and Kovačević, Jovana and Prodanović, Olivera and Todorović, Bratislav and Matović, Branko and Stanković, Mira and Maksimović, Vuk and Mutavdžić, Dragosav and Skočić, Miloš and Pešić, Mirjana and Prokić, Ljiljana and Radotić, Ksenija",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9129",
abstract = "The UV-B represents the minor fraction of the solar spectrum, while UV-C is not contained in natural solar radiation, but both radiation types can cause damaging effects in plants. Cell walls (CWs) are one of the targets for external stressors. Juvenile P. omorika trees were treated either with 21 day-high doses UV-B or with 7 day- UV-C in open-top chambers. Using spectroscopic and biochemical techniques, it was shown that the response to UV radiation includes numerous modifications in needle CW structure: relative content of xylan, xyloglucan, lignin and cellulose decreased; cellulose crystallinity changed; yield of lignin monomers with stronger connection of C[dbnd]C in side chain with the ring increased; re-distribution of inter- and intra-polymer H-bonds occurred. The recovery was mediated by an increase in the activities and changes in isoform profiles of CW bound covalent peroxidases (POD) and polyphenol oxidases (PO) (UV–B), and ionic POD and covalent PO (UV–C). A connection between activities of specific POD/PO isoforms and phenolic species (m- and p-coumaric acid, pinoresinol and cinnamic acid derivatives) was demonstrated, and supported by changes in the sRNA profile. In vivo fluorometry showed phenolics accumulation in needle epidermal CWs. These results imply transversal connections between polymers and changed mechanical properties of needle CW as a response to UV. The CW alterations enabled maintenance of physiological functions, as indicated by the preserved chlorophyll content and/or organization. The current study provides evidence that in conifers, needle CW response to both UV-B and UV-C includes biochemical modifications and structural remodeling. © 2021 Elsevier Masson SAS",
journal = "Plant Physiology and Biochemistry",
title = "Cell wall response to UV radiation in needles of Picea omorika",
volume = "161",
pages = "176-190",
doi = "10.1016/j.plaphy.2021.02.007"
}
Mitrović, A. Lj., Simonović-Radosavljević, J., Prokopijević, M., Spasojević, D., Kovačević, J., Prodanović, O., Todorović, B., Matović, B., Stanković, M., Maksimović, V., Mutavdžić, D., Skočić, M., Pešić, M., Prokić, L.,& Radotić, K. (2021). Cell wall response to UV radiation in needles of Picea omorika.
Plant Physiology and Biochemistry, 161, 176-190.
https://doi.org/10.1016/j.plaphy.2021.02.007
Mitrović AL, Simonović-Radosavljević J, Prokopijević M, Spasojević D, Kovačević J, Prodanović O, Todorović B, Matović B, Stanković M, Maksimović V, Mutavdžić D, Skočić M, Pešić M, Prokić L, Radotić K. Cell wall response to UV radiation in needles of Picea omorika. Plant Physiology and Biochemistry. 2021;161:176-190
Mitrović Aleksandra Lj., Simonović-Radosavljević Jasna, Prokopijević Miloš, Spasojević Dragica, Kovačević Jovana, Prodanović Olivera, Todorović Bratislav, Matović Branko, Stanković Mira, Maksimović Vuk, Mutavdžić Dragosav, Skočić Miloš, Pešić Mirjana, Prokić Ljiljana, Radotić Ksenija, "Cell wall response to UV radiation in needles of Picea omorika" Plant Physiology and Biochemistry, 161 (2021):176-190,
https://doi.org/10.1016/j.plaphy.2021.02.007 .

Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents

Milojkov, Dušan V.; Silvestre, Oscar F.; Stanić, Vojislav; Janjić, Goran V.; Mutavdžić, Dragosav R.; Milanović, Marija M.; Nieder, Jana B.

(2020)

TY  - JOUR
AU  - Milojkov, Dušan V.
AU  - Silvestre, Oscar F.
AU  - Stanić, Vojislav
AU  - Janjić, Goran V.
AU  - Mutavdžić, Dragosav R.
AU  - Milanović, Marija M.
AU  - Nieder, Jana B.
PY  - 2020
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8529
AB  - Fluorapatite doped with rare-earth elements has a wide-range of biomedical applications. Here, a new type of fluorapatite nanocrystals doped with praseodymium (FAP-Pr) with excitation-emission profiles in visible part of the spectrum is fabricated. Energy levels of Pr3+ activator ion contain metastable multiplet states that offer the possibility of efficient multicolor emission lines in FAP nanocrystals. Three types of FAP-Pr nanocrystals with 0.1%, 0.5% and 1% atomic percent of Pr3+ (along with the undoped FAP control sample) are studied. Their novel chemical production method is described, the FAP-Pr nanocrystals structure, biocompatibility and the suitability for cell imaging are analyzed. Physicochemical characterization confirms crystals down to nanometer size. In addition, quantum-chemical calculation predicts that Pr3+ ions are incorporated into the FAP crystal lattice at Ca2 (6 h) sites. In vitro viability results shows that FAP-Pr nanocrystals are nontoxic to live cells. Additionally, the cell uptake of the FAP-Pr nanocrystals is studied using fluorescence-based widefield and confocal microscopy. The nanocrystals show characteristic green emission at 545 nm (3P0→3H5 transition of Pr3+ ion) and orange emission at 600 nm (1D2→3H4), which we use to discriminate from cell autofluorescence background. Orthogonal projections across 3D confocal stacks show that the nanocrystals are able to enter the cells positioning themselves within the cytoplasm. Overall, the new FAP-Pr nanocrystals are biocompatible and of the tested types, the 0.5% Pr3+ doped nanocrystals show the highest promise as a tracking nanoparticle probe for bioimaging applications. © 2019
T2  - Journal of Luminescence
T1  - Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents
VL  - 217
SP  - 116757
DO  - 10.1016/j.jlumin.2019.116757
ER  - 
@article{
author = "Milojkov, Dušan V. and Silvestre, Oscar F. and Stanić, Vojislav and Janjić, Goran V. and Mutavdžić, Dragosav R. and Milanović, Marija M. and Nieder, Jana B.",
year = "2020",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/8529",
abstract = "Fluorapatite doped with rare-earth elements has a wide-range of biomedical applications. Here, a new type of fluorapatite nanocrystals doped with praseodymium (FAP-Pr) with excitation-emission profiles in visible part of the spectrum is fabricated. Energy levels of Pr3+ activator ion contain metastable multiplet states that offer the possibility of efficient multicolor emission lines in FAP nanocrystals. Three types of FAP-Pr nanocrystals with 0.1%, 0.5% and 1% atomic percent of Pr3+ (along with the undoped FAP control sample) are studied. Their novel chemical production method is described, the FAP-Pr nanocrystals structure, biocompatibility and the suitability for cell imaging are analyzed. Physicochemical characterization confirms crystals down to nanometer size. In addition, quantum-chemical calculation predicts that Pr3+ ions are incorporated into the FAP crystal lattice at Ca2 (6 h) sites. In vitro viability results shows that FAP-Pr nanocrystals are nontoxic to live cells. Additionally, the cell uptake of the FAP-Pr nanocrystals is studied using fluorescence-based widefield and confocal microscopy. The nanocrystals show characteristic green emission at 545 nm (3P0→3H5 transition of Pr3+ ion) and orange emission at 600 nm (1D2→3H4), which we use to discriminate from cell autofluorescence background. Orthogonal projections across 3D confocal stacks show that the nanocrystals are able to enter the cells positioning themselves within the cytoplasm. Overall, the new FAP-Pr nanocrystals are biocompatible and of the tested types, the 0.5% Pr3+ doped nanocrystals show the highest promise as a tracking nanoparticle probe for bioimaging applications. © 2019",
journal = "Journal of Luminescence",
title = "Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents",
volume = "217",
pages = "116757",
doi = "10.1016/j.jlumin.2019.116757"
}
Milojkov, D. V., Silvestre, O. F., Stanić, V., Janjić, G. V., Mutavdžić, D. R., Milanović, M. M.,& Nieder, J. B. (2020). Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents.
Journal of Luminescence, 217, 116757.
https://doi.org/10.1016/j.jlumin.2019.116757
Milojkov DV, Silvestre OF, Stanić V, Janjić GV, Mutavdžić DR, Milanović MM, Nieder JB. Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents. Journal of Luminescence. 2020;217:116757
Milojkov Dušan V., Silvestre Oscar F., Stanić Vojislav, Janjić Goran V., Mutavdžić Dragosav R., Milanović Marija M., Nieder Jana B., "Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents" Journal of Luminescence, 217 (2020):116757,
https://doi.org/10.1016/j.jlumin.2019.116757 .
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1
1

Effects of Ag + Ion Doping on UV Radiation Absorption and Luminescence Profiles of Fluorapatite Nanomaterials Obtained by Neutralization Method

Milojkov, Dušan V.; Stanić, Vojislav; Dimović, Slavko; Mutavdžić, Dragosav R.; Živković-Radovanović, Vukosava; Janjić, Goran V.; Radotić, Ksenija

(2019)

TY  - JOUR
AU  - Milojkov, Dušan V.
AU  - Stanić, Vojislav
AU  - Dimović, Slavko
AU  - Mutavdžić, Dragosav R.
AU  - Živković-Radovanović, Vukosava
AU  - Janjić, Goran V.
AU  - Radotić, Ksenija
PY  - 2019
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8629
AB  - In the present study we have analyzed effects of Ag+ ions doping on energetic profiles of nanophosphors materials based on fluorapatite crystal system. The UV radiation absorption and luminescence properties of monophase fluorapatite (FAP) and Ag+ doped fluorapatite (AgFAP) nanomaterials obtained by neutralization method were investigated using the photoluminescence spectrophotometry. The excitation-emission profiles of nanomaterials were analyzed statistically by MCR-ALS method and number of fluorophores was extracted. FAP lattice absorbed light at 350 nm in the UVA part of spectrum, and with increasing concentration of Ag+ ions new absorption maximum appeared at 270 nm in the UVC part. Fluorescence of FAP nanoparticles was in violet region of visible part of the spectrum, with a red shift to the green region when Ag+ was doped in lattice. MCR-ALS analyses of fluorescence spectra confirm formation of two maxima, at 484 and 505 nm, as a consequence of Ag+ ions doping in FAP lattice at Ca1 (4f) sites. The results of quantum chemical calculations showed that an Ag+ ion is stronger bonded to the binding site 1 (-1352:6 kcal/mol) than to the binding site 2 (-1249:0 kcal/mol). Considering that AgFAP1 nanopowder absorbs photons over all part of UV radiation spectrum, this material might be used as potential radiation protective nanomaterial. © 2019 Polish Academy of Sciences. All rights reserved.
T2  - Acta Physica Polonica A
T1  - Effects of Ag + Ion Doping on UV Radiation Absorption and Luminescence Profiles of Fluorapatite Nanomaterials Obtained by Neutralization Method
VL  - 136
IS  - 1
SP  - 86
EP  - 91
DO  - 10.12693/APhysPolA.136.86
ER  - 
@article{
author = "Milojkov, Dušan V. and Stanić, Vojislav and Dimović, Slavko and Mutavdžić, Dragosav R. and Živković-Radovanović, Vukosava and Janjić, Goran V. and Radotić, Ksenija",
year = "2019",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/8629",
abstract = "In the present study we have analyzed effects of Ag+ ions doping on energetic profiles of nanophosphors materials based on fluorapatite crystal system. The UV radiation absorption and luminescence properties of monophase fluorapatite (FAP) and Ag+ doped fluorapatite (AgFAP) nanomaterials obtained by neutralization method were investigated using the photoluminescence spectrophotometry. The excitation-emission profiles of nanomaterials were analyzed statistically by MCR-ALS method and number of fluorophores was extracted. FAP lattice absorbed light at 350 nm in the UVA part of spectrum, and with increasing concentration of Ag+ ions new absorption maximum appeared at 270 nm in the UVC part. Fluorescence of FAP nanoparticles was in violet region of visible part of the spectrum, with a red shift to the green region when Ag+ was doped in lattice. MCR-ALS analyses of fluorescence spectra confirm formation of two maxima, at 484 and 505 nm, as a consequence of Ag+ ions doping in FAP lattice at Ca1 (4f) sites. The results of quantum chemical calculations showed that an Ag+ ion is stronger bonded to the binding site 1 (-1352:6 kcal/mol) than to the binding site 2 (-1249:0 kcal/mol). Considering that AgFAP1 nanopowder absorbs photons over all part of UV radiation spectrum, this material might be used as potential radiation protective nanomaterial. © 2019 Polish Academy of Sciences. All rights reserved.",
journal = "Acta Physica Polonica A",
title = "Effects of Ag + Ion Doping on UV Radiation Absorption and Luminescence Profiles of Fluorapatite Nanomaterials Obtained by Neutralization Method",
volume = "136",
number = "1",
pages = "86-91",
doi = "10.12693/APhysPolA.136.86"
}
Milojkov, D. V., Stanić, V., Dimović, S., Mutavdžić, D. R., Živković-Radovanović, V., Janjić, G. V.,& Radotić, K. (2019). Effects of Ag + Ion Doping on UV Radiation Absorption and Luminescence Profiles of Fluorapatite Nanomaterials Obtained by Neutralization Method.
Acta Physica Polonica A, 136(1), 86-91.
https://doi.org/10.12693/APhysPolA.136.86
Milojkov DV, Stanić V, Dimović S, Mutavdžić DR, Živković-Radovanović V, Janjić GV, Radotić K. Effects of Ag + Ion Doping on UV Radiation Absorption and Luminescence Profiles of Fluorapatite Nanomaterials Obtained by Neutralization Method. Acta Physica Polonica A. 2019;136(1):86-91
Milojkov Dušan V., Stanić Vojislav, Dimović Slavko, Mutavdžić Dragosav R., Živković-Radovanović Vukosava, Janjić Goran V., Radotić Ksenija, "Effects of Ag + Ion Doping on UV Radiation Absorption and Luminescence Profiles of Fluorapatite Nanomaterials Obtained by Neutralization Method" Acta Physica Polonica A, 136, no. 1 (2019):86-91,
https://doi.org/10.12693/APhysPolA.136.86 .