Calcium signaling modulates the dynamics of cilia and flagella
Samo za registrovane korisnike
2020
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
To adapt to changing environments cells must signal and signaling requires messengers whose concentration varies with time in space. We here consider the messenger role of calcium ions implicated in regulation of the wave-like bending dynamics of cilia and flagella. The emphasis is on microtubules as polyelectrolytes serving as transmission lines for the flow of Ca2+ signals in the axoneme. This signaling is superimposed with a geometric clutch mechanism for the regulation of flagella bending dynamics and our modeling produces results in agreement with experimental data.
Ključne reči:
Calcium signaling / Cilium / Dynein motors / Flagellum / MicrotubuleIzvor:
European Biophysics Journal, 2020, 49, 7, 619-631Finansiranje / projekti:
- Uticaj elementarnih ekscitacija i konformacija na fizička svojstva novih materijala baziranih na jako korelisanim niskodimenzionalnim sistemima (RS-MESTD-Basic Research (BR or ON)-171009)
- Razvoj metoda, senzora, i sistema za praćenje kvaliteta vode, vazduha i zemljišta (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-43008)
- Fotonika mikro i nano strukturnih materijala (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45010)
- Provincial Secretariat for Higher Education and Scientific Research of AP Vojvodina [1144512708/201603]
DOI: 10.1007/s00249-020-01471-8
ISSN: 1432-1017
PubMed: 33105487
WoS: 000583986100001
Scopus: 2-s2.0-85094167202
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Satarić, Miljko V. AU - Zdravković, Slobodan AU - Nemeš, Tomas AU - Satarić, Bogdan M. PY - 2020 UR - https://vinar.vin.bg.ac.rs/handle/123456789/9719 AB - To adapt to changing environments cells must signal and signaling requires messengers whose concentration varies with time in space. We here consider the messenger role of calcium ions implicated in regulation of the wave-like bending dynamics of cilia and flagella. The emphasis is on microtubules as polyelectrolytes serving as transmission lines for the flow of Ca2+ signals in the axoneme. This signaling is superimposed with a geometric clutch mechanism for the regulation of flagella bending dynamics and our modeling produces results in agreement with experimental data. T2 - European Biophysics Journal T1 - Calcium signaling modulates the dynamics of cilia and flagella VL - 49 IS - 7 SP - 619 EP - 631 DO - 10.1007/s00249-020-01471-8 ER -
@article{ author = "Satarić, Miljko V. and Zdravković, Slobodan and Nemeš, Tomas and Satarić, Bogdan M.", year = "2020", abstract = "To adapt to changing environments cells must signal and signaling requires messengers whose concentration varies with time in space. We here consider the messenger role of calcium ions implicated in regulation of the wave-like bending dynamics of cilia and flagella. The emphasis is on microtubules as polyelectrolytes serving as transmission lines for the flow of Ca2+ signals in the axoneme. This signaling is superimposed with a geometric clutch mechanism for the regulation of flagella bending dynamics and our modeling produces results in agreement with experimental data.", journal = "European Biophysics Journal", title = "Calcium signaling modulates the dynamics of cilia and flagella", volume = "49", number = "7", pages = "619-631", doi = "10.1007/s00249-020-01471-8" }
Satarić, M. V., Zdravković, S., Nemeš, T.,& Satarić, B. M.. (2020). Calcium signaling modulates the dynamics of cilia and flagella. in European Biophysics Journal, 49(7), 619-631. https://doi.org/10.1007/s00249-020-01471-8
Satarić MV, Zdravković S, Nemeš T, Satarić BM. Calcium signaling modulates the dynamics of cilia and flagella. in European Biophysics Journal. 2020;49(7):619-631. doi:10.1007/s00249-020-01471-8 .
Satarić, Miljko V., Zdravković, Slobodan, Nemeš, Tomas, Satarić, Bogdan M., "Calcium signaling modulates the dynamics of cilia and flagella" in European Biophysics Journal, 49, no. 7 (2020):619-631, https://doi.org/10.1007/s00249-020-01471-8 . .