Calcium signaling modulates the dynamics of cilia and flagella
Само за регистроване кориснике
2020
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
To adapt to changing environments cells must signal and signaling requires messengers whose concentration varies with time in space. We here consider the messenger role of calcium ions implicated in regulation of the wave-like bending dynamics of cilia and flagella. The emphasis is on microtubules as polyelectrolytes serving as transmission lines for the flow of Ca2+ signals in the axoneme. This signaling is superimposed with a geometric clutch mechanism for the regulation of flagella bending dynamics and our modeling produces results in agreement with experimental data.
Кључне речи:
Calcium signaling / Cilium / Dynein motors / Flagellum / MicrotubuleИзвор:
European Biophysics Journal, 2020, 49, 7, 619-631Финансирање / пројекти:
- Утицај елементарних ексцитација и конформација на физичка својства нових материјала базираних на јако корелисаним нискодимензионалним системима (RS-MESTD-Basic Research (BR or ON)-171009)
- Развој метода, сензора, и система за праћење квалитета воде, ваздуха и земљишта (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-43008)
- Фотоника микро и нано структурних материјала (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45010)
- Provincial Secretariat for Higher Education and Scientific Research of AP Vojvodina [1144512708/201603]
DOI: 10.1007/s00249-020-01471-8
ISSN: 1432-1017
PubMed: 33105487
WoS: 000583986100001
Scopus: 2-s2.0-85094167202
Колекције
Институција/група
VinčaTY - JOUR AU - Satarić, Miljko V. AU - Zdravković, Slobodan AU - Nemeš, Tomas AU - Satarić, Bogdan M. PY - 2020 UR - https://vinar.vin.bg.ac.rs/handle/123456789/9719 AB - To adapt to changing environments cells must signal and signaling requires messengers whose concentration varies with time in space. We here consider the messenger role of calcium ions implicated in regulation of the wave-like bending dynamics of cilia and flagella. The emphasis is on microtubules as polyelectrolytes serving as transmission lines for the flow of Ca2+ signals in the axoneme. This signaling is superimposed with a geometric clutch mechanism for the regulation of flagella bending dynamics and our modeling produces results in agreement with experimental data. T2 - European Biophysics Journal T1 - Calcium signaling modulates the dynamics of cilia and flagella VL - 49 IS - 7 SP - 619 EP - 631 DO - 10.1007/s00249-020-01471-8 ER -
@article{ author = "Satarić, Miljko V. and Zdravković, Slobodan and Nemeš, Tomas and Satarić, Bogdan M.", year = "2020", abstract = "To adapt to changing environments cells must signal and signaling requires messengers whose concentration varies with time in space. We here consider the messenger role of calcium ions implicated in regulation of the wave-like bending dynamics of cilia and flagella. The emphasis is on microtubules as polyelectrolytes serving as transmission lines for the flow of Ca2+ signals in the axoneme. This signaling is superimposed with a geometric clutch mechanism for the regulation of flagella bending dynamics and our modeling produces results in agreement with experimental data.", journal = "European Biophysics Journal", title = "Calcium signaling modulates the dynamics of cilia and flagella", volume = "49", number = "7", pages = "619-631", doi = "10.1007/s00249-020-01471-8" }
Satarić, M. V., Zdravković, S., Nemeš, T.,& Satarić, B. M.. (2020). Calcium signaling modulates the dynamics of cilia and flagella. in European Biophysics Journal, 49(7), 619-631. https://doi.org/10.1007/s00249-020-01471-8
Satarić MV, Zdravković S, Nemeš T, Satarić BM. Calcium signaling modulates the dynamics of cilia and flagella. in European Biophysics Journal. 2020;49(7):619-631. doi:10.1007/s00249-020-01471-8 .
Satarić, Miljko V., Zdravković, Slobodan, Nemeš, Tomas, Satarić, Bogdan M., "Calcium signaling modulates the dynamics of cilia and flagella" in European Biophysics Journal, 49, no. 7 (2020):619-631, https://doi.org/10.1007/s00249-020-01471-8 . .