Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity
Само за регистроване кориснике
2015
Аутори
Radulović, Niko S.Ranđelović, Pavle J.
Stojanović, Nikola M.
Cakić, Nevenka D.
Bogdanović, Goran A.
Živanović, Ana V.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Callistemon citrinus (Myrtaceae) is a shrub native to Australia. Its flowers have been used as indigenous food among the aboriginal Australians. Numerous diseases, such as bacterial, fungal, viral and parasite infections have traditionally been treated with this plant. Gas chromatography mass spectrometry (GC/MS) analyses of the flower and leaf extracts of C citrinus revealed the presence of a major constituent, a phloroglucinol, dihydroxy-4-methoxyphenyl)-3-methylbutan-1-one (1) (up to 382.2 mg per 1 g of the flower extracts). Compound 1 was for the first time identified in this genus. This phloroglucinol exhibited potent antinociceptive and anti-inflammatory activities in a dose-dependent manner. In addition, this compound displayed strong in vitro antioxidant activity which could be easily connected with both anti-inflammatory and antinociceptive effects. Thus, compound 1, as a plant constituent present in the diet of Aboriginal people, that helps with inflammation and pain, could h...ave given them a better chance of survival in harsh conditions of the environment. (C) 2015 Elsevier Ltd. All rights reserved.
Кључне речи:
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-methylbutan-1-one / Flowers / Aboriginal bush foods / Antioxidant phloroglucinol / Antinociceptive / Anti-inflammatoryИзвор:
Food Research International, 2015, 77, SI, 280-289Финансирање / пројекти:
- Комбинаторне библиотеке хетерогених катализатора, природних производа, модификованих природних производа и њихових аналога: пут ка новим биолошки активним агенсима (RS-MESTD-Basic Research (BR or ON)-172061)
DOI: 10.1016/j.foodres.2015.02.023
ISSN: 0963-9969; 1873-7145
WoS: 000367409900025
Scopus: 2-s2.0-84947045789
Колекције
Институција/група
VinčaTY - JOUR AU - Radulović, Niko S. AU - Ranđelović, Pavle J. AU - Stojanović, Nikola M. AU - Cakić, Nevenka D. AU - Bogdanović, Goran A. AU - Živanović, Ana V. PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/874 AB - Callistemon citrinus (Myrtaceae) is a shrub native to Australia. Its flowers have been used as indigenous food among the aboriginal Australians. Numerous diseases, such as bacterial, fungal, viral and parasite infections have traditionally been treated with this plant. Gas chromatography mass spectrometry (GC/MS) analyses of the flower and leaf extracts of C citrinus revealed the presence of a major constituent, a phloroglucinol, dihydroxy-4-methoxyphenyl)-3-methylbutan-1-one (1) (up to 382.2 mg per 1 g of the flower extracts). Compound 1 was for the first time identified in this genus. This phloroglucinol exhibited potent antinociceptive and anti-inflammatory activities in a dose-dependent manner. In addition, this compound displayed strong in vitro antioxidant activity which could be easily connected with both anti-inflammatory and antinociceptive effects. Thus, compound 1, as a plant constituent present in the diet of Aboriginal people, that helps with inflammation and pain, could have given them a better chance of survival in harsh conditions of the environment. (C) 2015 Elsevier Ltd. All rights reserved. T2 - Food Research International T1 - Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity VL - 77 IS - SI SP - 280 EP - 289 DO - 10.1016/j.foodres.2015.02.023 ER -
@article{ author = "Radulović, Niko S. and Ranđelović, Pavle J. and Stojanović, Nikola M. and Cakić, Nevenka D. and Bogdanović, Goran A. and Živanović, Ana V.", year = "2015", abstract = "Callistemon citrinus (Myrtaceae) is a shrub native to Australia. Its flowers have been used as indigenous food among the aboriginal Australians. Numerous diseases, such as bacterial, fungal, viral and parasite infections have traditionally been treated with this plant. Gas chromatography mass spectrometry (GC/MS) analyses of the flower and leaf extracts of C citrinus revealed the presence of a major constituent, a phloroglucinol, dihydroxy-4-methoxyphenyl)-3-methylbutan-1-one (1) (up to 382.2 mg per 1 g of the flower extracts). Compound 1 was for the first time identified in this genus. This phloroglucinol exhibited potent antinociceptive and anti-inflammatory activities in a dose-dependent manner. In addition, this compound displayed strong in vitro antioxidant activity which could be easily connected with both anti-inflammatory and antinociceptive effects. Thus, compound 1, as a plant constituent present in the diet of Aboriginal people, that helps with inflammation and pain, could have given them a better chance of survival in harsh conditions of the environment. (C) 2015 Elsevier Ltd. All rights reserved.", journal = "Food Research International", title = "Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity", volume = "77", number = "SI", pages = "280-289", doi = "10.1016/j.foodres.2015.02.023" }
Radulović, N. S., Ranđelović, P. J., Stojanović, N. M., Cakić, N. D., Bogdanović, G. A.,& Živanović, A. V.. (2015). Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity. in Food Research International, 77(SI), 280-289. https://doi.org/10.1016/j.foodres.2015.02.023
Radulović NS, Ranđelović PJ, Stojanović NM, Cakić ND, Bogdanović GA, Živanović AV. Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity. in Food Research International. 2015;77(SI):280-289. doi:10.1016/j.foodres.2015.02.023 .
Radulović, Niko S., Ranđelović, Pavle J., Stojanović, Nikola M., Cakić, Nevenka D., Bogdanović, Goran A., Živanović, Ana V., "Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity" in Food Research International, 77, no. SI (2015):280-289, https://doi.org/10.1016/j.foodres.2015.02.023 . .