Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones
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2018
Authors
Pejović, AnkaMinić, Aleksandra
Bugarinović, Jovana P.
Pešić, Marko S.
Damljanović, Ivan S.
Stevanović, Dragana D.
Mihailović, Vladimir B.
Katanić, Jelena
Bogdanović, Goran A.
Article (Published version)
,
© 2018 Elsevier Ltd
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A new series of ferrocene-containing thiazolylpyrazoles – 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones have been synthesized using convenient one-pot three component condensation. Twelve newly synthesized compounds were fully characterized by spectroscopic (IR and NMR) and electrochemical methods (cyclic voltammetry). Single crystal X-ray structure analysis were undertaken on two compounds. The twelve novel ferrocene derivatives were also evaluated for antimicrobial activity. The results showed moderate antimicrobial activity of synthesized compounds with better effect on Candida albicans and Gram-negative bacteria than Gram-positive bacterial strains. © 2018 Elsevier Ltd
Keywords:
Ferrocene / 2-Pyrazolyl-1,3-Thiazolidin-4-one / Crystal structure / Electrochemistry / Antimicrobial activitySource:
Polyhedron, 2018, 155, 382-389Funding / projects:
- Simultaneous Bioremediation and Soilification of Degraded Areas to Preserve Natural Resources of Biologically Active Substances, and Development and Production of Biomaterials and Dietetic Products (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-43004)
- Novel Electrochemical and Chemical Methods in Synthesis of Organic Compounds of Interest for Medicine and Material Chemistry (RS-MESTD-Basic Research (BR or ON)-172034)
DOI: 10.1016/j.poly.2018.08.071
ISSN: 0277-5387
WoS: 000449137000046
Scopus: 2-s2.0-85053371174
URI
https://linkinghub.elsevier.com/retrieve/pii/S0277538718305394https://vinar.vin.bg.ac.rs/handle/123456789/7884
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VinčaTY - JOUR AU - Pejović, Anka AU - Minić, Aleksandra AU - Bugarinović, Jovana P. AU - Pešić, Marko S. AU - Damljanović, Ivan S. AU - Stevanović, Dragana D. AU - Mihailović, Vladimir B. AU - Katanić, Jelena AU - Bogdanović, Goran A. PY - 2018 UR - https://linkinghub.elsevier.com/retrieve/pii/S0277538718305394 UR - https://vinar.vin.bg.ac.rs/handle/123456789/7884 AB - A new series of ferrocene-containing thiazolylpyrazoles – 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones have been synthesized using convenient one-pot three component condensation. Twelve newly synthesized compounds were fully characterized by spectroscopic (IR and NMR) and electrochemical methods (cyclic voltammetry). Single crystal X-ray structure analysis were undertaken on two compounds. The twelve novel ferrocene derivatives were also evaluated for antimicrobial activity. The results showed moderate antimicrobial activity of synthesized compounds with better effect on Candida albicans and Gram-negative bacteria than Gram-positive bacterial strains. © 2018 Elsevier Ltd T2 - Polyhedron T1 - Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones VL - 155 SP - 382 EP - 389 DO - 10.1016/j.poly.2018.08.071 ER -
@article{ author = "Pejović, Anka and Minić, Aleksandra and Bugarinović, Jovana P. and Pešić, Marko S. and Damljanović, Ivan S. and Stevanović, Dragana D. and Mihailović, Vladimir B. and Katanić, Jelena and Bogdanović, Goran A.", year = "2018", abstract = "A new series of ferrocene-containing thiazolylpyrazoles – 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones have been synthesized using convenient one-pot three component condensation. Twelve newly synthesized compounds were fully characterized by spectroscopic (IR and NMR) and electrochemical methods (cyclic voltammetry). Single crystal X-ray structure analysis were undertaken on two compounds. The twelve novel ferrocene derivatives were also evaluated for antimicrobial activity. The results showed moderate antimicrobial activity of synthesized compounds with better effect on Candida albicans and Gram-negative bacteria than Gram-positive bacterial strains. © 2018 Elsevier Ltd", journal = "Polyhedron", title = "Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones", volume = "155", pages = "382-389", doi = "10.1016/j.poly.2018.08.071" }
Pejović, A., Minić, A., Bugarinović, J. P., Pešić, M. S., Damljanović, I. S., Stevanović, D. D., Mihailović, V. B., Katanić, J.,& Bogdanović, G. A.. (2018). Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones. in Polyhedron, 155, 382-389. https://doi.org/10.1016/j.poly.2018.08.071
Pejović A, Minić A, Bugarinović JP, Pešić MS, Damljanović IS, Stevanović DD, Mihailović VB, Katanić J, Bogdanović GA. Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones. in Polyhedron. 2018;155:382-389. doi:10.1016/j.poly.2018.08.071 .
Pejović, Anka, Minić, Aleksandra, Bugarinović, Jovana P., Pešić, Marko S., Damljanović, Ivan S., Stevanović, Dragana D., Mihailović, Vladimir B., Katanić, Jelena, Bogdanović, Goran A., "Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones" in Polyhedron, 155 (2018):382-389, https://doi.org/10.1016/j.poly.2018.08.071 . .