Alterations in binding of thyroid hormones to serum proteins in patients on regular haemodialysis
Nema prikaza
Autori
Durica, SnežanaKorićanac, Goran
Isenović, Esma R.
Radlović, Olivera
Ribarac-Stepić, Nevena B.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Content of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) was determined in the blood plasma of patients with severe renal failure treated by intermittent haemodialysis. Hormone binding to serum proteins was simultaneously analyzed. A decrease in the levels of T3 and T4, as well as an increase in the amount of TSH were observed in all analyzed specimens. However, a significant decline (p<0.025) was detected only in the level of T3 after haemodialysis as compared to the control values. The analysis of hormone binding to serum proteins using agarose gel electrophoresis indicated that higher levels of hormones were bound to albumin in the sera of patients and not of controls. Also a redistribution of hormones binding to albumin and prealbumin occurred in haemodialysis.
Ključne reči:
Binding proteins / Kidney insufficiency / Thyroid hormones / Thyrotropin / Thyroxine binding globulinIzvor:
Jugoslovenska Medicinska Biokemija, 1995, 14, 3-4, 111-117Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Durica, Snežana AU - Korićanac, Goran AU - Isenović, Esma R. AU - Radlović, Olivera AU - Ribarac-Stepić, Nevena B. PY - 1995 UR - https://vinar.vin.bg.ac.rs/handle/123456789/7838 AB - Content of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) was determined in the blood plasma of patients with severe renal failure treated by intermittent haemodialysis. Hormone binding to serum proteins was simultaneously analyzed. A decrease in the levels of T3 and T4, as well as an increase in the amount of TSH were observed in all analyzed specimens. However, a significant decline (p<0.025) was detected only in the level of T3 after haemodialysis as compared to the control values. The analysis of hormone binding to serum proteins using agarose gel electrophoresis indicated that higher levels of hormones were bound to albumin in the sera of patients and not of controls. Also a redistribution of hormones binding to albumin and prealbumin occurred in haemodialysis. T2 - Jugoslovenska Medicinska Biokemija T1 - Alterations in binding of thyroid hormones to serum proteins in patients on regular haemodialysis VL - 14 IS - 3-4 SP - 111 EP - 117 UR - https://hdl.handle.net/21.15107/rcub_vinar_7838 ER -
@article{ author = "Durica, Snežana and Korićanac, Goran and Isenović, Esma R. and Radlović, Olivera and Ribarac-Stepić, Nevena B.", year = "1995", abstract = "Content of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) was determined in the blood plasma of patients with severe renal failure treated by intermittent haemodialysis. Hormone binding to serum proteins was simultaneously analyzed. A decrease in the levels of T3 and T4, as well as an increase in the amount of TSH were observed in all analyzed specimens. However, a significant decline (p<0.025) was detected only in the level of T3 after haemodialysis as compared to the control values. The analysis of hormone binding to serum proteins using agarose gel electrophoresis indicated that higher levels of hormones were bound to albumin in the sera of patients and not of controls. Also a redistribution of hormones binding to albumin and prealbumin occurred in haemodialysis.", journal = "Jugoslovenska Medicinska Biokemija", title = "Alterations in binding of thyroid hormones to serum proteins in patients on regular haemodialysis", volume = "14", number = "3-4", pages = "111-117", url = "https://hdl.handle.net/21.15107/rcub_vinar_7838" }
Durica, S., Korićanac, G., Isenović, E. R., Radlović, O.,& Ribarac-Stepić, N. B.. (1995). Alterations in binding of thyroid hormones to serum proteins in patients on regular haemodialysis. in Jugoslovenska Medicinska Biokemija, 14(3-4), 111-117. https://hdl.handle.net/21.15107/rcub_vinar_7838
Durica S, Korićanac G, Isenović ER, Radlović O, Ribarac-Stepić NB. Alterations in binding of thyroid hormones to serum proteins in patients on regular haemodialysis. in Jugoslovenska Medicinska Biokemija. 1995;14(3-4):111-117. https://hdl.handle.net/21.15107/rcub_vinar_7838 .
Durica, Snežana, Korićanac, Goran, Isenović, Esma R., Radlović, Olivera, Ribarac-Stepić, Nevena B., "Alterations in binding of thyroid hormones to serum proteins in patients on regular haemodialysis" in Jugoslovenska Medicinska Biokemija, 14, no. 3-4 (1995):111-117, https://hdl.handle.net/21.15107/rcub_vinar_7838 .