Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy
Samo za registrovane korisnike
2018
Autori
Matijević, MilicaNešić, Maja
Stepić, Milutin
Radoičić, Marija B.
Šaponjić, Zoran
Petković, Marijana
Članak u časopisu (Objavljena verzija)
,
© 2018, Springer Science+Business Media, LLC, part of Springer Nature
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Photodynamic therapy implies a combined use of a photosensitizing medicament and low-intensity light to cause selective damage to the target tissue—tumor. As potential medicament, we use Ru(II)(dcbpy)2Cl2complex, and in order to achieve better photosensitization properties, the Ru complex was attached to the nano carrier—TiO2nanoparticles. Additionally, this nanocomposite system was encapsulated in the phospholipid vesicles, which could be classified as small unilamellar vesicles, based on the technique of production. The complex-release tests were performed under light illumination, at pH 5, characteristic for tumor cells` interior and compared with the release pattern at pH 7, characteristic for the serum, i.e. physiological solution.
Ključne reči:
photodynamic therapy / light controlled drug release / metallo-drug deliveryIzvor:
Optical and Quantum Electronics, 2018, 50, 6, 232-Finansiranje / projekti:
- Ispitivanje mehanizma reakcija kompleksa jona prelaznih metala sa biološki značajnim molekulima (RS-MESTD-Basic Research (BR or ON)-172011)
- Uticaj veličine, oblika i strukture nanočestica na njihova svojstva i svojstva nanokompozita (RS-MESTD-Basic Research (BR or ON)-172056)
- Fotonika mikro i nano strukturnih materijala (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45010)
DOI: 10.1007/s11082-018-1495-z
ISSN: 0306-8919; 1572-817X
WoS: 000433079400001
Scopus: 2-s2.0-85047448688
URI
http://link.springer.com/10.1007/s11082-018-1495-zhttps://vinar.vin.bg.ac.rs/handle/123456789/7697
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Matijević, Milica AU - Nešić, Maja AU - Stepić, Milutin AU - Radoičić, Marija B. AU - Šaponjić, Zoran AU - Petković, Marijana PY - 2018 UR - http://link.springer.com/10.1007/s11082-018-1495-z UR - https://vinar.vin.bg.ac.rs/handle/123456789/7697 AB - Photodynamic therapy implies a combined use of a photosensitizing medicament and low-intensity light to cause selective damage to the target tissue—tumor. As potential medicament, we use Ru(II)(dcbpy)2Cl2complex, and in order to achieve better photosensitization properties, the Ru complex was attached to the nano carrier—TiO2nanoparticles. Additionally, this nanocomposite system was encapsulated in the phospholipid vesicles, which could be classified as small unilamellar vesicles, based on the technique of production. The complex-release tests were performed under light illumination, at pH 5, characteristic for tumor cells` interior and compared with the release pattern at pH 7, characteristic for the serum, i.e. physiological solution. T2 - Optical and Quantum Electronics T1 - Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy VL - 50 IS - 6 SP - 232 DO - 10.1007/s11082-018-1495-z ER -
@article{ author = "Matijević, Milica and Nešić, Maja and Stepić, Milutin and Radoičić, Marija B. and Šaponjić, Zoran and Petković, Marijana", year = "2018", abstract = "Photodynamic therapy implies a combined use of a photosensitizing medicament and low-intensity light to cause selective damage to the target tissue—tumor. As potential medicament, we use Ru(II)(dcbpy)2Cl2complex, and in order to achieve better photosensitization properties, the Ru complex was attached to the nano carrier—TiO2nanoparticles. Additionally, this nanocomposite system was encapsulated in the phospholipid vesicles, which could be classified as small unilamellar vesicles, based on the technique of production. The complex-release tests were performed under light illumination, at pH 5, characteristic for tumor cells` interior and compared with the release pattern at pH 7, characteristic for the serum, i.e. physiological solution.", journal = "Optical and Quantum Electronics", title = "Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy", volume = "50", number = "6", pages = "232", doi = "10.1007/s11082-018-1495-z" }
Matijević, M., Nešić, M., Stepić, M., Radoičić, M. B., Šaponjić, Z.,& Petković, M.. (2018). Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy. in Optical and Quantum Electronics, 50(6), 232. https://doi.org/10.1007/s11082-018-1495-z
Matijević M, Nešić M, Stepić M, Radoičić MB, Šaponjić Z, Petković M. Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy. in Optical and Quantum Electronics. 2018;50(6):232. doi:10.1007/s11082-018-1495-z .
Matijević, Milica, Nešić, Maja, Stepić, Milutin, Radoičić, Marija B., Šaponjić, Zoran, Petković, Marijana, "Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy" in Optical and Quantum Electronics, 50, no. 6 (2018):232, https://doi.org/10.1007/s11082-018-1495-z . .