Apatite formation on nanomaterial calcium phosphate/poly-DL-lactide-co-glycolide in simulated body fluid
Нема приказа
Аутори
Vukelić, MarijaMitić, Žarko
Miljković, Miroslav
Živković, Jelena
Ignjatović, Nenad L.
Uskoković, Dragan
Živanov Čurlis, Jelena
Vasiljević, Perica
Najman, Stevo
Чланак у часопису
Метаподаци
Приказ свих података о документуАпстракт
Simulated body fluid (SBF) is an artificial fluid which has ionic composition and ionic concentration similar to human blood plasma. Purpose: This paper compares the interaction between the nanomaterial containing calcium phosphate/poly-dl-lactide-co-glycolide (N-CP/PLGA) and SBF, in order to investigate whether and to what extent inorganic ionic composition of human blood plasma leads to the aforementioned changes in the material. Methods: N-CP/PLGA was incubated for 1, 2, 3, and 5 weeks in SBF. The surface of the material was analyzed on SEM-EDS and FTIR spectrometer, while SBF was subjected to pH and electrical conductivity measurement. Results: Our results indicate that dissolution of the polymer component of the material N-CP/PLGA and precipitation of the material similar to hydroxyapatite on its surface are based on the morphologic changes seen in this material. Conclusions: The mechanism of the apatite formation on the bioceramic surface was intensively studied and was considere...d crucial in designing the new biomaterials. The results obtained in this work indicate that N-CP/PLGA may be a good candidate for application to bone regeneration.
Кључне речи:
calcium phosphate and poly-dl-lactide-co-glycolide / simulated body fluid / bioceramicsИзвор:
Journal of Applied Biomaterials and Functional Materials, 2012, 43-48Издавач:
- Milano : Wichtig Publishing
Финансирање / пројекти:
- Молекуларно дизајнирање наночестица контролисаних морфолошких и физичко-хемијских карактеристика и функционалних материјала на њиховој основи (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45004)
DOI: 10.5301/JABFM.2012.9274
ISSN: 2280-8000
WoS: 000309586600007
Scopus: 2-s2.0-84863962495
Колекције
Институција/група
VinčaTY - JOUR AU - Vukelić, Marija AU - Mitić, Žarko AU - Miljković, Miroslav AU - Živković, Jelena AU - Ignjatović, Nenad L. AU - Uskoković, Dragan AU - Živanov Čurlis, Jelena AU - Vasiljević, Perica AU - Najman, Stevo PY - 2012 UR - http://dais.sanu.ac.rs/123456789/489 UR - https://vinar.vin.bg.ac.rs/handle/123456789/7451 AB - Simulated body fluid (SBF) is an artificial fluid which has ionic composition and ionic concentration similar to human blood plasma. Purpose: This paper compares the interaction between the nanomaterial containing calcium phosphate/poly-dl-lactide-co-glycolide (N-CP/PLGA) and SBF, in order to investigate whether and to what extent inorganic ionic composition of human blood plasma leads to the aforementioned changes in the material. Methods: N-CP/PLGA was incubated for 1, 2, 3, and 5 weeks in SBF. The surface of the material was analyzed on SEM-EDS and FTIR spectrometer, while SBF was subjected to pH and electrical conductivity measurement. Results: Our results indicate that dissolution of the polymer component of the material N-CP/PLGA and precipitation of the material similar to hydroxyapatite on its surface are based on the morphologic changes seen in this material. Conclusions: The mechanism of the apatite formation on the bioceramic surface was intensively studied and was considered crucial in designing the new biomaterials. The results obtained in this work indicate that N-CP/PLGA may be a good candidate for application to bone regeneration. PB - Milano : Wichtig Publishing T2 - Journal of Applied Biomaterials and Functional Materials T1 - Apatite formation on nanomaterial calcium phosphate/poly-DL-lactide-co-glycolide in simulated body fluid SP - 43 EP - 48 DO - 10.5301/JABFM.2012.9274 ER -
@article{ author = "Vukelić, Marija and Mitić, Žarko and Miljković, Miroslav and Živković, Jelena and Ignjatović, Nenad L. and Uskoković, Dragan and Živanov Čurlis, Jelena and Vasiljević, Perica and Najman, Stevo", year = "2012", abstract = "Simulated body fluid (SBF) is an artificial fluid which has ionic composition and ionic concentration similar to human blood plasma. Purpose: This paper compares the interaction between the nanomaterial containing calcium phosphate/poly-dl-lactide-co-glycolide (N-CP/PLGA) and SBF, in order to investigate whether and to what extent inorganic ionic composition of human blood plasma leads to the aforementioned changes in the material. Methods: N-CP/PLGA was incubated for 1, 2, 3, and 5 weeks in SBF. The surface of the material was analyzed on SEM-EDS and FTIR spectrometer, while SBF was subjected to pH and electrical conductivity measurement. Results: Our results indicate that dissolution of the polymer component of the material N-CP/PLGA and precipitation of the material similar to hydroxyapatite on its surface are based on the morphologic changes seen in this material. Conclusions: The mechanism of the apatite formation on the bioceramic surface was intensively studied and was considered crucial in designing the new biomaterials. The results obtained in this work indicate that N-CP/PLGA may be a good candidate for application to bone regeneration.", publisher = "Milano : Wichtig Publishing", journal = "Journal of Applied Biomaterials and Functional Materials", title = "Apatite formation on nanomaterial calcium phosphate/poly-DL-lactide-co-glycolide in simulated body fluid", pages = "43-48", doi = "10.5301/JABFM.2012.9274" }
Vukelić, M., Mitić, Ž., Miljković, M., Živković, J., Ignjatović, N. L., Uskoković, D., Živanov Čurlis, J., Vasiljević, P.,& Najman, S.. (2012). Apatite formation on nanomaterial calcium phosphate/poly-DL-lactide-co-glycolide in simulated body fluid. in Journal of Applied Biomaterials and Functional Materials Milano : Wichtig Publishing., 43-48. https://doi.org/10.5301/JABFM.2012.9274
Vukelić M, Mitić Ž, Miljković M, Živković J, Ignjatović NL, Uskoković D, Živanov Čurlis J, Vasiljević P, Najman S. Apatite formation on nanomaterial calcium phosphate/poly-DL-lactide-co-glycolide in simulated body fluid. in Journal of Applied Biomaterials and Functional Materials. 2012;:43-48. doi:10.5301/JABFM.2012.9274 .
Vukelić, Marija, Mitić, Žarko, Miljković, Miroslav, Živković, Jelena, Ignjatović, Nenad L., Uskoković, Dragan, Živanov Čurlis, Jelena, Vasiljević, Perica, Najman, Stevo, "Apatite formation on nanomaterial calcium phosphate/poly-DL-lactide-co-glycolide in simulated body fluid" in Journal of Applied Biomaterials and Functional Materials (2012):43-48, https://doi.org/10.5301/JABFM.2012.9274 . .