Heart Failure Models: Traditional and Novel Therapy
Nema prikaza
Autori
Haidara, Mohamed A.Assiri, Abdullah S.
Yassin, Hanaa Z.
Ammar, Hania I.
Obradović, Milan M.
Isenović, Esma R.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Cardiovascular disease (CVD) is among the most major causes of morbidity and mortality worldwide. Great progress has been made in the management of CVD which has been influenced by the use of experimental animal models. These models provided information at cellular and molecular levels and allowed the development of treatment strategies. CVD models have been developed in many species, including large animals (e.g. pigs and dogs) and small animals (e.g. rats and mice). Although, no model can solely reproduce clinical HF, simulations of heart failure (HF) are available to experimentally tackle certain queries not easily resolved in humans. Induced HF may also be produced experimentally through myocardial infarction (MI), pressure loading, or volume loading. Volume loading is useful to look at hormone and electrolyte disturbances, while pressure loading models is helpful to study ventricular hypertrophy, cellular imbalance and vascular changes in HF. Coronary heart disease is assessed in ...MI animal models. In this review we describe various experimental models used to study the pathophysiology of HF.
Ključne reči:
Heart failure / animal models / statins / diuretics / stem cell therapyIzvor:
Current Vascular Pharmacology, 2015, 13, 5, 658-669Finansiranje / projekti:
- Hormonska regulacija ekspresije i aktivnosti azot oksid sintaze i natrijum-kalijumove pumpe u eksperimentalnim modelima insulinske rezistencije, dijabetesa i kardiovaskularnih poremećaja (RS-MESTD-Basic Research (BR or ON)-173033)
DOI: 10.2174/1570161113666150212151506
ISSN: 1570-1611; 1875-6212
PubMed: 25675330
WoS: 000360503100011
Scopus: 2-s2.0-84931314943
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Haidara, Mohamed A. AU - Assiri, Abdullah S. AU - Yassin, Hanaa Z. AU - Ammar, Hania I. AU - Obradović, Milan M. AU - Isenović, Esma R. PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/716 AB - Cardiovascular disease (CVD) is among the most major causes of morbidity and mortality worldwide. Great progress has been made in the management of CVD which has been influenced by the use of experimental animal models. These models provided information at cellular and molecular levels and allowed the development of treatment strategies. CVD models have been developed in many species, including large animals (e.g. pigs and dogs) and small animals (e.g. rats and mice). Although, no model can solely reproduce clinical HF, simulations of heart failure (HF) are available to experimentally tackle certain queries not easily resolved in humans. Induced HF may also be produced experimentally through myocardial infarction (MI), pressure loading, or volume loading. Volume loading is useful to look at hormone and electrolyte disturbances, while pressure loading models is helpful to study ventricular hypertrophy, cellular imbalance and vascular changes in HF. Coronary heart disease is assessed in MI animal models. In this review we describe various experimental models used to study the pathophysiology of HF. T2 - Current Vascular Pharmacology T1 - Heart Failure Models: Traditional and Novel Therapy VL - 13 IS - 5 SP - 658 EP - 669 DO - 10.2174/1570161113666150212151506 ER -
@article{ author = "Haidara, Mohamed A. and Assiri, Abdullah S. and Yassin, Hanaa Z. and Ammar, Hania I. and Obradović, Milan M. and Isenović, Esma R.", year = "2015", abstract = "Cardiovascular disease (CVD) is among the most major causes of morbidity and mortality worldwide. Great progress has been made in the management of CVD which has been influenced by the use of experimental animal models. These models provided information at cellular and molecular levels and allowed the development of treatment strategies. CVD models have been developed in many species, including large animals (e.g. pigs and dogs) and small animals (e.g. rats and mice). Although, no model can solely reproduce clinical HF, simulations of heart failure (HF) are available to experimentally tackle certain queries not easily resolved in humans. Induced HF may also be produced experimentally through myocardial infarction (MI), pressure loading, or volume loading. Volume loading is useful to look at hormone and electrolyte disturbances, while pressure loading models is helpful to study ventricular hypertrophy, cellular imbalance and vascular changes in HF. Coronary heart disease is assessed in MI animal models. In this review we describe various experimental models used to study the pathophysiology of HF.", journal = "Current Vascular Pharmacology", title = "Heart Failure Models: Traditional and Novel Therapy", volume = "13", number = "5", pages = "658-669", doi = "10.2174/1570161113666150212151506" }
Haidara, M. A., Assiri, A. S., Yassin, H. Z., Ammar, H. I., Obradović, M. M.,& Isenović, E. R.. (2015). Heart Failure Models: Traditional and Novel Therapy. in Current Vascular Pharmacology, 13(5), 658-669. https://doi.org/10.2174/1570161113666150212151506
Haidara MA, Assiri AS, Yassin HZ, Ammar HI, Obradović MM, Isenović ER. Heart Failure Models: Traditional and Novel Therapy. in Current Vascular Pharmacology. 2015;13(5):658-669. doi:10.2174/1570161113666150212151506 .
Haidara, Mohamed A., Assiri, Abdullah S., Yassin, Hanaa Z., Ammar, Hania I., Obradović, Milan M., Isenović, Esma R., "Heart Failure Models: Traditional and Novel Therapy" in Current Vascular Pharmacology, 13, no. 5 (2015):658-669, https://doi.org/10.2174/1570161113666150212151506 . .