Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples
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Radosavljević-Stevanović, NatašaMarković, Jelena P.
Agatonović-Kustrin, Snežana
Ražić, Slavica
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Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.
Keywords:
cannabinoid biosynthesis / GC-FID / atomic spectrometry / chemometricsSource:
Natural Product Research, 2014, 28, 8, 511-516Funding / projects:
- Advanced technologies for monitoring and environmental protection from chemical pollutants and radiation burden (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-43009)
DOI: 10.1080/14786419.2014.880912
ISSN: 1478-6419; 1478-6427
PubMed: 24483128
WoS: 000334070700002
Scopus: 2-s2.0-84898057017
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VinčaTY - JOUR AU - Radosavljević-Stevanović, Nataša AU - Marković, Jelena P. AU - Agatonović-Kustrin, Snežana AU - Ražić, Slavica PY - 2014 UR - https://vinar.vin.bg.ac.rs/handle/123456789/5945 AB - Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids. T2 - Natural Product Research T1 - Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples VL - 28 IS - 8 SP - 511 EP - 516 DO - 10.1080/14786419.2014.880912 ER -
@article{ author = "Radosavljević-Stevanović, Nataša and Marković, Jelena P. and Agatonović-Kustrin, Snežana and Ražić, Slavica", year = "2014", abstract = "Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.", journal = "Natural Product Research", title = "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples", volume = "28", number = "8", pages = "511-516", doi = "10.1080/14786419.2014.880912" }
Radosavljević-Stevanović, N., Marković, J. P., Agatonović-Kustrin, S.,& Ražić, S.. (2014). Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research, 28(8), 511-516. https://doi.org/10.1080/14786419.2014.880912
Radosavljević-Stevanović N, Marković JP, Agatonović-Kustrin S, Ražić S. Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research. 2014;28(8):511-516. doi:10.1080/14786419.2014.880912 .
Radosavljević-Stevanović, Nataša, Marković, Jelena P., Agatonović-Kustrin, Snežana, Ražić, Slavica, "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples" in Natural Product Research, 28, no. 8 (2014):511-516, https://doi.org/10.1080/14786419.2014.880912 . .