Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome
Само за регистроване кориснике
2014
Аутори
Abate, NicolaSallam, Hanaa S.
Rizzo, Manfredi
Nikolić, Dragana
Obradović, Milan M.
Bjelogrlic, Predrag
Isenović, Esma R.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Resistin is an adipocyte-and monocyte-derived cytokine which has been implicated in the modulation of insulin action, energy, glucose and lipid homeostasis. Resistin has been associated with insulin resistance and many of its known complications. As a molecular link between metabolic signals, inflammation, and vascular dysfunction, resistin can be proposed as playing a significant role in the heightened inflammatory state induced by metabolic stress linked to excessive caloric intake, thus contributing to the risk for metabolic syndrome (MetS), type 2 diabetes (T2DM), and cardiovascular diseases (CVD). In this review, we highlighted the role of resistin, as an inflammatory cytokine, in the development of CVD, T2DM and the MetS.
Кључне речи:
Resistin / type 2 diabetes / cardiovascular diseases / metabolic syndromeИзвор:
Current Pharmaceutical Design, 2014, 20, 31, 4961-4969Финансирање / пројекти:
- Хормонска регулација експресије и активности азот оксид синтазе и натријум-калијумове пумпе у експерименталним моделима инсулинске резистенције, дијабетеса и кардиоваскуларних поремећаја (RS-MESTD-Basic Research (BR or ON)-173033)
Колекције
Институција/група
VinčaTY - JOUR AU - Abate, Nicola AU - Sallam, Hanaa S. AU - Rizzo, Manfredi AU - Nikolić, Dragana AU - Obradović, Milan M. AU - Bjelogrlic, Predrag AU - Isenović, Esma R. PY - 2014 UR - https://vinar.vin.bg.ac.rs/handle/123456789/56 AB - Resistin is an adipocyte-and monocyte-derived cytokine which has been implicated in the modulation of insulin action, energy, glucose and lipid homeostasis. Resistin has been associated with insulin resistance and many of its known complications. As a molecular link between metabolic signals, inflammation, and vascular dysfunction, resistin can be proposed as playing a significant role in the heightened inflammatory state induced by metabolic stress linked to excessive caloric intake, thus contributing to the risk for metabolic syndrome (MetS), type 2 diabetes (T2DM), and cardiovascular diseases (CVD). In this review, we highlighted the role of resistin, as an inflammatory cytokine, in the development of CVD, T2DM and the MetS. T2 - Current Pharmaceutical Design T1 - Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome VL - 20 IS - 31 SP - 4961 EP - 4969 UR - https://hdl.handle.net/21.15107/rcub_vinar_56 ER -
@article{ author = "Abate, Nicola and Sallam, Hanaa S. and Rizzo, Manfredi and Nikolić, Dragana and Obradović, Milan M. and Bjelogrlic, Predrag and Isenović, Esma R.", year = "2014", abstract = "Resistin is an adipocyte-and monocyte-derived cytokine which has been implicated in the modulation of insulin action, energy, glucose and lipid homeostasis. Resistin has been associated with insulin resistance and many of its known complications. As a molecular link between metabolic signals, inflammation, and vascular dysfunction, resistin can be proposed as playing a significant role in the heightened inflammatory state induced by metabolic stress linked to excessive caloric intake, thus contributing to the risk for metabolic syndrome (MetS), type 2 diabetes (T2DM), and cardiovascular diseases (CVD). In this review, we highlighted the role of resistin, as an inflammatory cytokine, in the development of CVD, T2DM and the MetS.", journal = "Current Pharmaceutical Design", title = "Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome", volume = "20", number = "31", pages = "4961-4969", url = "https://hdl.handle.net/21.15107/rcub_vinar_56" }
Abate, N., Sallam, H. S., Rizzo, M., Nikolić, D., Obradović, M. M., Bjelogrlic, P.,& Isenović, E. R.. (2014). Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome. in Current Pharmaceutical Design, 20(31), 4961-4969. https://hdl.handle.net/21.15107/rcub_vinar_56
Abate N, Sallam HS, Rizzo M, Nikolić D, Obradović MM, Bjelogrlic P, Isenović ER. Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome. in Current Pharmaceutical Design. 2014;20(31):4961-4969. https://hdl.handle.net/21.15107/rcub_vinar_56 .
Abate, Nicola, Sallam, Hanaa S., Rizzo, Manfredi, Nikolić, Dragana, Obradović, Milan M., Bjelogrlic, Predrag, Isenović, Esma R., "Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome" in Current Pharmaceutical Design, 20, no. 31 (2014):4961-4969, https://hdl.handle.net/21.15107/rcub_vinar_56 .