Sensitivity and accuracy of organic matrix-assisted Laser desorption and ionisation mass spectrometry of FeCl3 is higher than in in matrix-free approach
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Autori
Radisavljevic, MajaKamceva, Tina
Vukićević, Iva A.
Nišavić, Marija
Milovanović, Milan
Petković, Marijana
Članak u časopisu
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
We compare the quality and reliability of laser desorption and ionisation mass spectra of FeCl3 acquired without the assistance of the matrix with the spectra acquired with different organic matrix molecules. Generally, inorganic salts tend to form clusters upon laser irradiation, the signals of which can be easily distinguished from ions arising from the matrix. In the presence of a matrix, cluster ions are, however, mostly suppressed. We have compared the number of analyte signals, accuracy of determination of isotope composition of the analyte and the sensitivity of FeCl3 detection between different approaches. The results obtained imply that the sensitivity of mass spectrometric analysis of FeCl3 is somewhat higher when matrices are applied than in the matrix-free approach. Among all matrices tested in this work, F20TPP seems to be the most promising for further applications as a matrix for mass spectrometry of inorganic salts.
Ključne reči:
FeCl3 / MALDI-ToF-MS / LDI ToF MS / organic matricesIzvor:
European Journal of Mass Spectrometry, 2013, 19, 2, 77-89Finansiranje / projekti:
- Ispitivanje mehanizma reakcija kompleksa jona prelaznih metala sa biološki značajnim molekulima (RS-MESTD-Basic Research (BR or ON)-172011)
- German Academic Exchange Service
DOI: 10.1255/ejms.1217
ISSN: 1469-0667; 1751-6838
PubMed: 24261080
WoS: 000322418600001
Scopus: 2-s2.0-84880913906
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Radisavljevic, Maja AU - Kamceva, Tina AU - Vukićević, Iva A. AU - Nišavić, Marija AU - Milovanović, Milan AU - Petković, Marijana PY - 2013 UR - https://vinar.vin.bg.ac.rs/handle/123456789/5605 AB - We compare the quality and reliability of laser desorption and ionisation mass spectra of FeCl3 acquired without the assistance of the matrix with the spectra acquired with different organic matrix molecules. Generally, inorganic salts tend to form clusters upon laser irradiation, the signals of which can be easily distinguished from ions arising from the matrix. In the presence of a matrix, cluster ions are, however, mostly suppressed. We have compared the number of analyte signals, accuracy of determination of isotope composition of the analyte and the sensitivity of FeCl3 detection between different approaches. The results obtained imply that the sensitivity of mass spectrometric analysis of FeCl3 is somewhat higher when matrices are applied than in the matrix-free approach. Among all matrices tested in this work, F20TPP seems to be the most promising for further applications as a matrix for mass spectrometry of inorganic salts. T2 - European Journal of Mass Spectrometry T1 - Sensitivity and accuracy of organic matrix-assisted Laser desorption and ionisation mass spectrometry of FeCl3 is higher than in in matrix-free approach VL - 19 IS - 2 SP - 77 EP - 89 DO - 10.1255/ejms.1217 ER -
@article{ author = "Radisavljevic, Maja and Kamceva, Tina and Vukićević, Iva A. and Nišavić, Marija and Milovanović, Milan and Petković, Marijana", year = "2013", abstract = "We compare the quality and reliability of laser desorption and ionisation mass spectra of FeCl3 acquired without the assistance of the matrix with the spectra acquired with different organic matrix molecules. Generally, inorganic salts tend to form clusters upon laser irradiation, the signals of which can be easily distinguished from ions arising from the matrix. In the presence of a matrix, cluster ions are, however, mostly suppressed. We have compared the number of analyte signals, accuracy of determination of isotope composition of the analyte and the sensitivity of FeCl3 detection between different approaches. The results obtained imply that the sensitivity of mass spectrometric analysis of FeCl3 is somewhat higher when matrices are applied than in the matrix-free approach. Among all matrices tested in this work, F20TPP seems to be the most promising for further applications as a matrix for mass spectrometry of inorganic salts.", journal = "European Journal of Mass Spectrometry", title = "Sensitivity and accuracy of organic matrix-assisted Laser desorption and ionisation mass spectrometry of FeCl3 is higher than in in matrix-free approach", volume = "19", number = "2", pages = "77-89", doi = "10.1255/ejms.1217" }
Radisavljevic, M., Kamceva, T., Vukićević, I. A., Nišavić, M., Milovanović, M.,& Petković, M.. (2013). Sensitivity and accuracy of organic matrix-assisted Laser desorption and ionisation mass spectrometry of FeCl3 is higher than in in matrix-free approach. in European Journal of Mass Spectrometry, 19(2), 77-89. https://doi.org/10.1255/ejms.1217
Radisavljevic M, Kamceva T, Vukićević IA, Nišavić M, Milovanović M, Petković M. Sensitivity and accuracy of organic matrix-assisted Laser desorption and ionisation mass spectrometry of FeCl3 is higher than in in matrix-free approach. in European Journal of Mass Spectrometry. 2013;19(2):77-89. doi:10.1255/ejms.1217 .
Radisavljevic, Maja, Kamceva, Tina, Vukićević, Iva A., Nišavić, Marija, Milovanović, Milan, Petković, Marijana, "Sensitivity and accuracy of organic matrix-assisted Laser desorption and ionisation mass spectrometry of FeCl3 is higher than in in matrix-free approach" in European Journal of Mass Spectrometry, 19, no. 2 (2013):77-89, https://doi.org/10.1255/ejms.1217 . .