Comparison of MALDI-TOF mass spectra of [PdCl(dien)]Cl and [Ru(en)(2)Cl-2]Cl acquired with different matrices
Apstrakt
In this work, the matrix-assisted laser desorption and ionization time-of-flight (MALDI-TOF) mass spectra of two cationic complexes, i.e., [PdCl(dien)]Cl and [Ru(en)(7)Cl-2]Cl, acquired under different conditions were analyzed. The spectra were recorded with three matrices with or without trifluoroacetic acid (TFA), i.e., two traditional matrices, i.e., 2,5-dihydroxybenzoic acid and alpha-cyano-hydroxycinnamic acid, and one flavonoid, quercetin. The spectra acquired with quercetin appeared to be the simplest, whereas in the spectra obtained with other matrices, peaks arising either from the addition of matrix molecules or from the fragmentation products were detectable. Addition of TFA did not complicate the spectra of the Pd(II) and Ru(III) complexes when the traditional matrices were used. On the other hand, the spectra of Pd complex were simpler, whereas the addition of TFA in the case of the Ru complex resulted in a higher number of peaks, some of which could not be identified. Tak...en together, the results of this study once more emphasize the differences arising in the MALDI-TOF mass spectra of transition metal complexes in dependence on the applied matrix.
Ključne reči:
MALDI-TOF MS / metallo-drugs / matrix / peak assignmentIzvor:
Journal of the Serbian Chemical Society, 2011, 76, 12, 1687-1701Finansiranje / projekti:
- Ispitivanje mehanizma reakcija kompleksa jona prelaznih metala sa biološki značajnim molekulima (RS-MESTD-Basic Research (BR or ON)-172011)
DOI: 10.2298/JSC110201145D
ISSN: 0352-5139
WoS: 000298777900009
Scopus: 2-s2.0-84858686872
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Damnjanović, Bojana AU - Petrović, Biljana AU - Dimitrić-Marković, Jasmina AU - Petković, Marijana PY - 2011 UR - https://vinar.vin.bg.ac.rs/handle/123456789/4637 AB - In this work, the matrix-assisted laser desorption and ionization time-of-flight (MALDI-TOF) mass spectra of two cationic complexes, i.e., [PdCl(dien)]Cl and [Ru(en)(7)Cl-2]Cl, acquired under different conditions were analyzed. The spectra were recorded with three matrices with or without trifluoroacetic acid (TFA), i.e., two traditional matrices, i.e., 2,5-dihydroxybenzoic acid and alpha-cyano-hydroxycinnamic acid, and one flavonoid, quercetin. The spectra acquired with quercetin appeared to be the simplest, whereas in the spectra obtained with other matrices, peaks arising either from the addition of matrix molecules or from the fragmentation products were detectable. Addition of TFA did not complicate the spectra of the Pd(II) and Ru(III) complexes when the traditional matrices were used. On the other hand, the spectra of Pd complex were simpler, whereas the addition of TFA in the case of the Ru complex resulted in a higher number of peaks, some of which could not be identified. Taken together, the results of this study once more emphasize the differences arising in the MALDI-TOF mass spectra of transition metal complexes in dependence on the applied matrix. T2 - Journal of the Serbian Chemical Society T1 - Comparison of MALDI-TOF mass spectra of [PdCl(dien)]Cl and [Ru(en)(2)Cl-2]Cl acquired with different matrices VL - 76 IS - 12 SP - 1687 EP - 1701 DO - 10.2298/JSC110201145D ER -
@article{ author = "Damnjanović, Bojana and Petrović, Biljana and Dimitrić-Marković, Jasmina and Petković, Marijana", year = "2011", abstract = "In this work, the matrix-assisted laser desorption and ionization time-of-flight (MALDI-TOF) mass spectra of two cationic complexes, i.e., [PdCl(dien)]Cl and [Ru(en)(7)Cl-2]Cl, acquired under different conditions were analyzed. The spectra were recorded with three matrices with or without trifluoroacetic acid (TFA), i.e., two traditional matrices, i.e., 2,5-dihydroxybenzoic acid and alpha-cyano-hydroxycinnamic acid, and one flavonoid, quercetin. The spectra acquired with quercetin appeared to be the simplest, whereas in the spectra obtained with other matrices, peaks arising either from the addition of matrix molecules or from the fragmentation products were detectable. Addition of TFA did not complicate the spectra of the Pd(II) and Ru(III) complexes when the traditional matrices were used. On the other hand, the spectra of Pd complex were simpler, whereas the addition of TFA in the case of the Ru complex resulted in a higher number of peaks, some of which could not be identified. Taken together, the results of this study once more emphasize the differences arising in the MALDI-TOF mass spectra of transition metal complexes in dependence on the applied matrix.", journal = "Journal of the Serbian Chemical Society", title = "Comparison of MALDI-TOF mass spectra of [PdCl(dien)]Cl and [Ru(en)(2)Cl-2]Cl acquired with different matrices", volume = "76", number = "12", pages = "1687-1701", doi = "10.2298/JSC110201145D" }
Damnjanović, B., Petrović, B., Dimitrić-Marković, J.,& Petković, M.. (2011). Comparison of MALDI-TOF mass spectra of [PdCl(dien)]Cl and [Ru(en)(2)Cl-2]Cl acquired with different matrices. in Journal of the Serbian Chemical Society, 76(12), 1687-1701. https://doi.org/10.2298/JSC110201145D
Damnjanović B, Petrović B, Dimitrić-Marković J, Petković M. Comparison of MALDI-TOF mass spectra of [PdCl(dien)]Cl and [Ru(en)(2)Cl-2]Cl acquired with different matrices. in Journal of the Serbian Chemical Society. 2011;76(12):1687-1701. doi:10.2298/JSC110201145D .
Damnjanović, Bojana, Petrović, Biljana, Dimitrić-Marković, Jasmina, Petković, Marijana, "Comparison of MALDI-TOF mass spectra of [PdCl(dien)]Cl and [Ru(en)(2)Cl-2]Cl acquired with different matrices" in Journal of the Serbian Chemical Society, 76, no. 12 (2011):1687-1701, https://doi.org/10.2298/JSC110201145D . .