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Application of the EIIP/ISM bioinformatics concept in development of new drugs
(Current Medicinal Chemistry, 2007)
The development of a new therapeutic drug is a complex, lengthy and expensive process. On average, only one out of 10,000 - 30,000 originally synthesized compounds will clear all the hurdles on the way to becoming a ...
Low temperature Ce2Si2O7 polymorph formed by mechanical activation
(Materials Chemistry and Physics, 2006)
Studying solid state reaction between mechanically activated oxide powders of CeO2 and quartz-SiO2, we obtained directly during heat treatment, the low temperature polymorph of Ce2Si2O7 instead of the high temperature ...
Diamond synthesized at low pressure
(Chemistry and Physics of Carbon, 2004)
Sol-gel synthesis and characterization of iron doped mullite
(Journal of Alloys and Compounds, 2014)
Amorphous powders of iron doped 3:2 mullite (3Al(2)O(3)center dot 2SiO(2)) were prepared by sol-gel combustion process using ethanol-water solutions of Al(III) nitrate, Fe(III) nitrate, TEOS and urea. Compositions up to ...
Curing time effect on compressive strength and incremental leaching rates of Cs-137 and Co-60 in cement immobilized sludge
(Progress in Nuclear Energy, 2006)
In this experiment, after 180 days of measuring, the compressive strength development for various curing histories was investigated with particular regard to the influences of curing time points with the incremental leaching ...
Discovery of New Therapeutic Targets by the Informational Spectrum Method
(Current Protein and Peptide Science, 2008)
The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational ...
Biomedical potential of the reactive oxygen species generation and quenching by fullerenes (C-60)
(Biomaterials, 2008)
Fullerene (C-60), a third carbon allotrope, is a classical engineered material with the potential application in biomedicine. One of the biologically most relevant features of C-60 is the ability to quench various free ...
AIDS vaccine: State of the art at the beginning of the third millennium
(International Reviews of Immunology, 2004)
This overview briefly summarizes the current status of global AIDS epidemic, especially pointing out how this pandemic looked in the last year of the second millennium. We also give a brief overview of the state of the art ...
Multivariate statistical analysis of hydrochemical and radiological data of Serbian spa waters
(Journal of Geochemical Exploration, 2012)
Principal component analysis (PCA) and hierarchical cluster analysis (HCA) have been applied in order to recognize and classify spa waters collected at 30 sites on Serbian territory. The data set comprised 30 observations ...
The effect of lignin on the structure and characteristics of composite coatings electrodeposited on titanium
(Progress in Organic Coatings, 2012)
Composite coatings based on lignin, obtained by electrophoretic deposition (EPD) on titanium, were investigated. The aim of this work was to produce hydroxyapatite/lignin (HAP/Lig) coatings on titanium and to investigate ...