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Приказ резултата 1031-1040 од 1040
Testing the photo-sensitive nanocomposite system for potential controlled metallo-drug delivery
(Springer, 2016)
Photo-responsive drug release systems are promising for drug delivery applications due to many benefits compared to conventional chemotherapy such as targeted, controlled release of a drug and reduced toxicity to healthy ...
Dependence of the quality of SALDI TOF MS analysis on the TiO2 nanocrystals size and shape
(Springer, 2016)
Titanium dioxide is widely used substrate for laser desorption and ionization [(SA)LDI] mass spectrometry. As the semiconductor with high UV absorbance and rapid energy transfer to analytes, TiO2 provides soft and efficient ...
Anti-Tumour Activity of Fotemustine and Protons in Combination with Bevacizumab
(Chemotherapy, 2010)
Background: Metastatic melanoma is one of the most aggressive tumours and is also very resistant to current therapeutic approaches. The aim of this investigation was the in vitro study of the anti-proliferative effects of ...
Citrus flavanones mildly interfere with pituitary -thyroid axis in old-aged male rats
(Acta Histochemica, 2017)
Citrus flavanones naringenin (NAR) and hesperetin (HES) are potent antioxidants that may contribute to maintenance of health at old age by improving cardiovascular and metabolic status. However, they may also affect thyroid ...
Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples
(Biomedicine and Pharmacotherapy, 2014)
p53, p16 and PTEN are the most commonly altered tumor suppressor genes in human cancers. In the present study, we compared the presence of individual and multiple alterations of these tumor suppressors in non-small cell ...
Identification of differentially expressed mRNA transcripts in drug-resistant versus parental human melanoma cell lines
(Anticancer Research, 2006)
Background: Malignant melanoma resistance to chemotherapy remains a major limitation to treatment. Our aim was to identify genes associated with drug resistance, in order to better understand the molecular events underlying ...
Quantification of Transforming Growth Factor Beta 1 Levels in Metastatic Axillary Lymph Node Tissue Extracts from Breast Cancer Patients A New Specimen Source
(Analytical and Quantitative Cytology and Histology, 2009)
OBJECTIVE: To use cytoplasmic tissue extract as a new specimen source to quantify transforming growth factor beta 1 (TGF beta 1) protein in metastatic axillary lymph node tissue (ALNT) of breast cancer (BC) patients and ...
Association of leptin gene polymorphism G-2548A with metabolic and anthropometric parameters in obese patients in a Serbian population: pilot study
(Clinical Lipidology, 2014)
Aim: The aim of this pilot study was to investigate possible associations of LEP promoter polymorphism LEP G-2548A and obesity-associated metabolic and antropometric parameters in obese population. Materials and methods: ...
Case with triple-negative breast cancer shows overexpression of both cFOS and TGF-beta 1 in node-positive tissue
(Personalized Medicine, 2016)
We present herein a case report style article on a rare advanced triple-negative breast cancer (TNBC) patient with 6-month disease-free interval, and 10-month overall survival. Our results demonstrate that the poor clinical ...
Genomic instability in drug-resistant human melanoma cell lines detected by Alu-I-arbitrary-primed PCR
(Anticancer Research, 2003)
Destabilization of the genome seems to be an important step in the generation of drug resistance. Since malignant melanoma is extremely resistant to chemotherapy, we used human melanoma cell lines as a model to investigate ...