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Levels of sCD40 Ligand in Chronic and Acute Coronary Syndromes and its Relation to Angiographic Extent of Coronary Arterial Narrowing

dc.creatorFouad, Hanan H.
dc.creatorAl-Dera, Husain
dc.creatorBakhoum, Sameh W.
dc.creatorRashed, Laila A.
dc.creatorSayed, Rehab H.
dc.creatorRateb, Moshira A.
dc.creatorHaidara, Mohamed A.
dc.creatorSoskić, Sanja S.
dc.creatorIsenović, Esma R.
dc.date.accessioned2018-03-01T21:16:52Z
dc.date.available2018-03-01T21:16:52Z
dc.date.issued2010
dc.identifier.issn0003-3197
dc.identifier.urihttps://vinar.vin.bg.ac.rs/handle/123456789/4039
dc.description.abstractWe determined the serum levels of soluble CD40 ligand (sCD4OL) in patients with chronic coronary artery disease (CAD) and acute coronary syndrome (ACS). Patients with unstable angina (UA) and myocardial infarction (MI) showed significantly higher levels (P LT .001) of sCD4OL compared with patients with stable angina (SA) and controls; particularly, high levels occurred in patients with UA (UA: 9.23 +/- 2.92, MI: 7.38 +/- 1.05, SA: 4.42 +/- 1.08; control: 4.01 +/- 0.87 ng/mL). There was no significant difference in sCD4OL levels between patients with UA and MI or between patients with SA and controls. Levels of sCD4OL did not show any significant correlation with peak creatine kinase (CK), CK-MB isoenzyme activity in patients with MI, troponin T serum levels in patients with UA or with culprit vessel (CV) complexity score (CVCS), type of CV lesion, or vessel score in patients with UA or MI. These results suggest that CD40L plays a pathogenic role in triggering ACS.en
dc.relationResearch Center, Faculty of Medicine, Cairo University, Egypt, Ministry of Science, Republic of Serbia [143030]
dc.rightsrestrictedAccessen
dc.sourceAngiologyen
dc.subjectcoronary artery diseaseen
dc.subjectacute coronary syndromeen
dc.subjectCD40 liganden
dc.subjectcoronary angiogramen
dc.titleLevels of sCD40 Ligand in Chronic and Acute Coronary Syndromes and its Relation to Angiographic Extent of Coronary Arterial Narrowingen
dc.typearticleen
dcterms.abstractБакхоум, Самех W.; Расхед, Лаила A.; Саyед, Рехаб Х.; Ратеб, Мосхира A.; Хаидара, Мохамед A.; Aл-Дера, Хусаин; Фоуад, Ханан Х.; Соскић Сања; Исеновић Есма;
dc.citation.volume61
dc.citation.issue6
dc.citation.spage567
dc.citation.epage573
dc.identifier.wos000279760800008
dc.identifier.doi10.1177/0003319709356785
dc.citation.rankM23
dc.identifier.pmid20304868
dc.identifier.scopus2-s2.0-77955020141


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