Simple criterion for selection of flavonoid compounds with anti-HIV activity
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2007
Authors
Veljković, VeljkoMouscadet, Jean-Francois
Veljković, Nevena V.
Glišić, Sanja
Debyser, Zeger
Article (Published version)
Metadata
Show full item recordAbstract
Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity. (c) 2007 Elsevier Ltd. All rights reserved.
Keywords:
flavonoids / in silico screening / anti-HIV compoundsSource:
Bioorganic and Medicinal Chemistry Letters, 2007, 17, 5, 1226-1232Funding / projects:
- European Commission [TRIoH integrated project, Contract No. LSHB-CT-2003-50348]
- Identifikacija i karakterizacija ćelijskih kofaktora HIV-a i njihova moguća primena u preventivi i terapiji (RS-MESTD-MPN2006-2010-143001)
DOI: 10.1016/j.bmcl.2006.12.029
ISSN: 0960-894X
PubMed: 17189684
WoS: 000244943300018
Scopus: 2-s2.0-33846959847
Institution/Community
VinčaTY - JOUR AU - Veljković, Veljko AU - Mouscadet, Jean-Francois AU - Veljković, Nevena V. AU - Glišić, Sanja AU - Debyser, Zeger PY - 2007 UR - https://vinar.vin.bg.ac.rs/handle/123456789/3166 AB - Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity. (c) 2007 Elsevier Ltd. All rights reserved. T2 - Bioorganic and Medicinal Chemistry Letters T1 - Simple criterion for selection of flavonoid compounds with anti-HIV activity VL - 17 IS - 5 SP - 1226 EP - 1232 DO - 10.1016/j.bmcl.2006.12.029 ER -
@article{ author = "Veljković, Veljko and Mouscadet, Jean-Francois and Veljković, Nevena V. and Glišić, Sanja and Debyser, Zeger", year = "2007", abstract = "Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity. (c) 2007 Elsevier Ltd. All rights reserved.", journal = "Bioorganic and Medicinal Chemistry Letters", title = "Simple criterion for selection of flavonoid compounds with anti-HIV activity", volume = "17", number = "5", pages = "1226-1232", doi = "10.1016/j.bmcl.2006.12.029" }
Veljković, V., Mouscadet, J., Veljković, N. V., Glišić, S.,& Debyser, Z.. (2007). Simple criterion for selection of flavonoid compounds with anti-HIV activity. in Bioorganic and Medicinal Chemistry Letters, 17(5), 1226-1232. https://doi.org/10.1016/j.bmcl.2006.12.029
Veljković V, Mouscadet J, Veljković NV, Glišić S, Debyser Z. Simple criterion for selection of flavonoid compounds with anti-HIV activity. in Bioorganic and Medicinal Chemistry Letters. 2007;17(5):1226-1232. doi:10.1016/j.bmcl.2006.12.029 .
Veljković, Veljko, Mouscadet, Jean-Francois, Veljković, Nevena V., Glišić, Sanja, Debyser, Zeger, "Simple criterion for selection of flavonoid compounds with anti-HIV activity" in Bioorganic and Medicinal Chemistry Letters, 17, no. 5 (2007):1226-1232, https://doi.org/10.1016/j.bmcl.2006.12.029 . .