Safety and ethical consideration of AIDS vaccine
Apstrakt
It has been demonstrated that HIV-1 gp120 resembles several important properties of immunoglobulins allowing it strong influence on the human immune system, especially through induction of the deceptive imprinting and deregulation of the immune network. On the other hand there are many unanswered questions concerning properties and control of the genetically modified viruses and bacteria used as vectors in AIDS vaccines. This situation opens a serious question about the safety of vectored AIDS vaccine and the ethics of their trials in humans.
Ključne reči:
HIV-1 gp120 / vectored AIDS vaccines / safety / clinical trialIzvor:
International Reviews of Immunology, 2004, 23, 5-6, 465-486
DOI: 10.1080/08830180490432866
ISSN: 0883-0185
PubMed: 15370278
WoS: 000223983900009
Scopus: 2-s2.0-4644326954
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Veljković, Veljko AU - Prljić, Jelena AU - Veljković, Tatjana PY - 2004 UR - https://vinar.vin.bg.ac.rs/handle/123456789/2809 AB - It has been demonstrated that HIV-1 gp120 resembles several important properties of immunoglobulins allowing it strong influence on the human immune system, especially through induction of the deceptive imprinting and deregulation of the immune network. On the other hand there are many unanswered questions concerning properties and control of the genetically modified viruses and bacteria used as vectors in AIDS vaccines. This situation opens a serious question about the safety of vectored AIDS vaccine and the ethics of their trials in humans. T2 - International Reviews of Immunology T1 - Safety and ethical consideration of AIDS vaccine VL - 23 IS - 5-6 SP - 465 EP - 486 DO - 10.1080/08830180490432866 ER -
@article{ author = "Veljković, Veljko and Prljić, Jelena and Veljković, Tatjana", year = "2004", abstract = "It has been demonstrated that HIV-1 gp120 resembles several important properties of immunoglobulins allowing it strong influence on the human immune system, especially through induction of the deceptive imprinting and deregulation of the immune network. On the other hand there are many unanswered questions concerning properties and control of the genetically modified viruses and bacteria used as vectors in AIDS vaccines. This situation opens a serious question about the safety of vectored AIDS vaccine and the ethics of their trials in humans.", journal = "International Reviews of Immunology", title = "Safety and ethical consideration of AIDS vaccine", volume = "23", number = "5-6", pages = "465-486", doi = "10.1080/08830180490432866" }
Veljković, V., Prljić, J.,& Veljković, T.. (2004). Safety and ethical consideration of AIDS vaccine. in International Reviews of Immunology, 23(5-6), 465-486. https://doi.org/10.1080/08830180490432866
Veljković V, Prljić J, Veljković T. Safety and ethical consideration of AIDS vaccine. in International Reviews of Immunology. 2004;23(5-6):465-486. doi:10.1080/08830180490432866 .
Veljković, Veljko, Prljić, Jelena, Veljković, Tatjana, "Safety and ethical consideration of AIDS vaccine" in International Reviews of Immunology, 23, no. 5-6 (2004):465-486, https://doi.org/10.1080/08830180490432866 . .