Application of VIP/NTM-reactive natural antibodies in therapy of HIV disease
Apstrakt
In sera of HIV-infected individuals natural antibodies recognizing nonimmunogenic C-terminal domain of the second conserved region of HIV-1 gp120 and the vasoactive intestinal peptide (VIP) were identified. It has been demonstrated that these antibodies are significantly more prevalent in asymptomatic carriers than in AIDS patients and that their titer strongly correlates with disease progression. These findings point out the VIP/C2-reactive natural antibodies as an important agent for immunotherapy of HIV disease.
Ključne reči:
gp120 / VIP / natural antibodies / immunotherapyIzvor:
International Reviews of Immunology, 2004, 23, 5-6, 437-445
DOI: 10.1080/08830180490432820
ISSN: 0883-0185
PubMed: 15370275
WoS: 000223983900006
Scopus: 2-s2.0-4644247611
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Veljković, Veljko AU - Metlaš, Radmila PY - 2004 UR - https://vinar.vin.bg.ac.rs/handle/123456789/2807 AB - In sera of HIV-infected individuals natural antibodies recognizing nonimmunogenic C-terminal domain of the second conserved region of HIV-1 gp120 and the vasoactive intestinal peptide (VIP) were identified. It has been demonstrated that these antibodies are significantly more prevalent in asymptomatic carriers than in AIDS patients and that their titer strongly correlates with disease progression. These findings point out the VIP/C2-reactive natural antibodies as an important agent for immunotherapy of HIV disease. T2 - International Reviews of Immunology T1 - Application of VIP/NTM-reactive natural antibodies in therapy of HIV disease VL - 23 IS - 5-6 SP - 437 EP - 445 DO - 10.1080/08830180490432820 ER -
@article{ author = "Veljković, Veljko and Metlaš, Radmila", year = "2004", abstract = "In sera of HIV-infected individuals natural antibodies recognizing nonimmunogenic C-terminal domain of the second conserved region of HIV-1 gp120 and the vasoactive intestinal peptide (VIP) were identified. It has been demonstrated that these antibodies are significantly more prevalent in asymptomatic carriers than in AIDS patients and that their titer strongly correlates with disease progression. These findings point out the VIP/C2-reactive natural antibodies as an important agent for immunotherapy of HIV disease.", journal = "International Reviews of Immunology", title = "Application of VIP/NTM-reactive natural antibodies in therapy of HIV disease", volume = "23", number = "5-6", pages = "437-445", doi = "10.1080/08830180490432820" }
Veljković, V.,& Metlaš, R.. (2004). Application of VIP/NTM-reactive natural antibodies in therapy of HIV disease. in International Reviews of Immunology, 23(5-6), 437-445. https://doi.org/10.1080/08830180490432820
Veljković V, Metlaš R. Application of VIP/NTM-reactive natural antibodies in therapy of HIV disease. in International Reviews of Immunology. 2004;23(5-6):437-445. doi:10.1080/08830180490432820 .
Veljković, Veljko, Metlaš, Radmila, "Application of VIP/NTM-reactive natural antibodies in therapy of HIV disease" in International Reviews of Immunology, 23, no. 5-6 (2004):437-445, https://doi.org/10.1080/08830180490432820 . .