Effect of immobilization and cold stress on sympatho-adrenal system in rats exposed to long-term cold
Апстракт
In the present study we examined changes in plasma levels of catecholamines, corticosterone and adrenomedullary TH gene expression after a short (2 h) and long-term (28 days) cold exposure, as well as in the cold adapted rats exposed to immobilization. Long-term cold produced a significant elevation of basal plasma levels of noradrenaline, but not of adrenaline, corticosterone and adrenal TH mRNA. Cold-adapted rats exposed to immobilization further significantly elevated plasma levels of catecholamines, corticosterone and adrenal TH mRNA, in comparison with repeated short (2 h) exposure to cold. The response of these animals was more pronounced in comparison with naive rats exposed to the same stressor at room temperature. Based on the results obtained it can be concluded that the rats exposed to long-term cold are able to respond to another stressor by a higher activation of the sympatho-adrenal system as compared to the rats kept at room temperature.
Кључне речи:
catecholamines / corticosterone / adrenal TH mRNA / cold stress / immobilizationИзвор:
Jugoslovenska Medicinska Biohemija, 2001, 20, 4, 217-222Колекције
Институција/група
VinčaTY - JOUR AU - Dronjak, Slađana AU - Kvetnansky, R AU - Jezova, D AU - Varagic, V PY - 2001 UR - https://vinar.vin.bg.ac.rs/handle/123456789/2490 AB - In the present study we examined changes in plasma levels of catecholamines, corticosterone and adrenomedullary TH gene expression after a short (2 h) and long-term (28 days) cold exposure, as well as in the cold adapted rats exposed to immobilization. Long-term cold produced a significant elevation of basal plasma levels of noradrenaline, but not of adrenaline, corticosterone and adrenal TH mRNA. Cold-adapted rats exposed to immobilization further significantly elevated plasma levels of catecholamines, corticosterone and adrenal TH mRNA, in comparison with repeated short (2 h) exposure to cold. The response of these animals was more pronounced in comparison with naive rats exposed to the same stressor at room temperature. Based on the results obtained it can be concluded that the rats exposed to long-term cold are able to respond to another stressor by a higher activation of the sympatho-adrenal system as compared to the rats kept at room temperature. T2 - Jugoslovenska Medicinska Biohemija T1 - Effect of immobilization and cold stress on sympatho-adrenal system in rats exposed to long-term cold VL - 20 IS - 4 SP - 217 EP - 222 UR - https://hdl.handle.net/21.15107/rcub_vinar_2490 ER -
@article{ author = "Dronjak, Slađana and Kvetnansky, R and Jezova, D and Varagic, V", year = "2001", abstract = "In the present study we examined changes in plasma levels of catecholamines, corticosterone and adrenomedullary TH gene expression after a short (2 h) and long-term (28 days) cold exposure, as well as in the cold adapted rats exposed to immobilization. Long-term cold produced a significant elevation of basal plasma levels of noradrenaline, but not of adrenaline, corticosterone and adrenal TH mRNA. Cold-adapted rats exposed to immobilization further significantly elevated plasma levels of catecholamines, corticosterone and adrenal TH mRNA, in comparison with repeated short (2 h) exposure to cold. The response of these animals was more pronounced in comparison with naive rats exposed to the same stressor at room temperature. Based on the results obtained it can be concluded that the rats exposed to long-term cold are able to respond to another stressor by a higher activation of the sympatho-adrenal system as compared to the rats kept at room temperature.", journal = "Jugoslovenska Medicinska Biohemija", title = "Effect of immobilization and cold stress on sympatho-adrenal system in rats exposed to long-term cold", volume = "20", number = "4", pages = "217-222", url = "https://hdl.handle.net/21.15107/rcub_vinar_2490" }
Dronjak, S., Kvetnansky, R., Jezova, D.,& Varagic, V.. (2001). Effect of immobilization and cold stress on sympatho-adrenal system in rats exposed to long-term cold. in Jugoslovenska Medicinska Biohemija, 20(4), 217-222. https://hdl.handle.net/21.15107/rcub_vinar_2490
Dronjak S, Kvetnansky R, Jezova D, Varagic V. Effect of immobilization and cold stress on sympatho-adrenal system in rats exposed to long-term cold. in Jugoslovenska Medicinska Biohemija. 2001;20(4):217-222. https://hdl.handle.net/21.15107/rcub_vinar_2490 .
Dronjak, Slađana, Kvetnansky, R, Jezova, D, Varagic, V, "Effect of immobilization and cold stress on sympatho-adrenal system in rats exposed to long-term cold" in Jugoslovenska Medicinska Biohemija, 20, no. 4 (2001):217-222, https://hdl.handle.net/21.15107/rcub_vinar_2490 .