Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties
Samo za registrovane korisnike
2018
Autori
Babić-Stojić, Branka S.Jokanović, Vukoman R.
Milivojević, Dušan
Pozek, Miroslav
Jagličić, Zvonko
Makovec, Darko
Jović Orsini, Nataša
Marković, Mirjana
Arsikin, Katarina M.
Paunović, Verica G.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Ultrasmall iron oxide (USPIO) nanoparticles, with diameter mostly less than 3 nm dispersed in an organic carrier fluid were synthesized by polyol route. The evolution of ZFC-FC magnetization curves with temperature, as well as the shift of the ac susceptibility peaks upon changing the frequency, reveal that the nanoparticles in the fluid are non-interacting and superparamagnetic with the blocking temperature T-B similar to 10 K. The Mossbauer spectra analysis proposed the core/shell structure of the nanoparticles consisting of stoichiometric gamma-Fe2O3 core and non-stoichiometric shell. The nanoparticle surface layer has a great influence on their properties which is principally manifested in significant reduction of the magnetization and in a large increase in magnetic anisotropy. Magnetic moments do not saturate in fields up to 5 T, even at the lowest measured temperature, T = 5 K. The average magnetic particle diameter is changed from 1.3 to 1.8 nm with increasing magnetic field fr...om 0 to 5 T which is noticeably smaller than the particle sizes measured by TEM. The estimated effective magnetic anisotropy constant value, K-eff = 2 x 10(5) J/m(3), is two orders of magnitude higher than in the bulk maghemite. Measurements of the longitudinal and transverse NMR relaxivity parameters on water diluted nanoparticle dispersions at 1.5 T gave the values r(1) = 0.028 mmol(-1) s(-1), r(2) = 0.050 mmol(-1) s(-1) and their ratio r(2)/r(1) = 1.8. Continuous increase of the T-1-weighted MRI signal intensity with increasing Fe concentration in the nanoparticle dispersions was observed which makes this ferrofluid to behave as a positive T-1 contrast agent. (C) 2017 Elsevier B.V. All rights reserved.
Ključne reči:
Ultrasmall iron oxide nanoparticles / Magnetic anisotropy / Mossbauer spectroscopy / NMR relaxivities / Magnetic resonance imagingIzvor:
Current Applied Physics, 2018, 18, 2, 141-149Finansiranje / projekti:
- Hemijsko i strukturno dizajniranje nanomaterijala za primenu u medicini i inženjerstvu tkiva (RS-MESTD-Basic Research (BR or ON)-172026)
- Modulacija signalnih puteva koji kontrolišu intracelularni energetski balans u terapiji tumora i neuro-imuno-endokrinih poremećaja (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41025)
DOI: 10.1016/j.cap.2017.11.017
ISSN: 1567-1739; 1878-1675
WoS: 000419050900002
Scopus: 2-s2.0-85034856465
Institucija/grupa
VinčaTY - JOUR AU - Babić-Stojić, Branka S. AU - Jokanović, Vukoman R. AU - Milivojević, Dušan AU - Pozek, Miroslav AU - Jagličić, Zvonko AU - Makovec, Darko AU - Jović Orsini, Nataša AU - Marković, Mirjana AU - Arsikin, Katarina M. AU - Paunović, Verica G. PY - 2018 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1889 AB - Ultrasmall iron oxide (USPIO) nanoparticles, with diameter mostly less than 3 nm dispersed in an organic carrier fluid were synthesized by polyol route. The evolution of ZFC-FC magnetization curves with temperature, as well as the shift of the ac susceptibility peaks upon changing the frequency, reveal that the nanoparticles in the fluid are non-interacting and superparamagnetic with the blocking temperature T-B similar to 10 K. The Mossbauer spectra analysis proposed the core/shell structure of the nanoparticles consisting of stoichiometric gamma-Fe2O3 core and non-stoichiometric shell. The nanoparticle surface layer has a great influence on their properties which is principally manifested in significant reduction of the magnetization and in a large increase in magnetic anisotropy. Magnetic moments do not saturate in fields up to 5 T, even at the lowest measured temperature, T = 5 K. The average magnetic particle diameter is changed from 1.3 to 1.8 nm with increasing magnetic field from 0 to 5 T which is noticeably smaller than the particle sizes measured by TEM. The estimated effective magnetic anisotropy constant value, K-eff = 2 x 10(5) J/m(3), is two orders of magnitude higher than in the bulk maghemite. Measurements of the longitudinal and transverse NMR relaxivity parameters on water diluted nanoparticle dispersions at 1.5 T gave the values r(1) = 0.028 mmol(-1) s(-1), r(2) = 0.050 mmol(-1) s(-1) and their ratio r(2)/r(1) = 1.8. Continuous increase of the T-1-weighted MRI signal intensity with increasing Fe concentration in the nanoparticle dispersions was observed which makes this ferrofluid to behave as a positive T-1 contrast agent. (C) 2017 Elsevier B.V. All rights reserved. T2 - Current Applied Physics T1 - Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties VL - 18 IS - 2 SP - 141 EP - 149 DO - 10.1016/j.cap.2017.11.017 ER -
@article{ author = "Babić-Stojić, Branka S. and Jokanović, Vukoman R. and Milivojević, Dušan and Pozek, Miroslav and Jagličić, Zvonko and Makovec, Darko and Jović Orsini, Nataša and Marković, Mirjana and Arsikin, Katarina M. and Paunović, Verica G.", year = "2018", abstract = "Ultrasmall iron oxide (USPIO) nanoparticles, with diameter mostly less than 3 nm dispersed in an organic carrier fluid were synthesized by polyol route. The evolution of ZFC-FC magnetization curves with temperature, as well as the shift of the ac susceptibility peaks upon changing the frequency, reveal that the nanoparticles in the fluid are non-interacting and superparamagnetic with the blocking temperature T-B similar to 10 K. The Mossbauer spectra analysis proposed the core/shell structure of the nanoparticles consisting of stoichiometric gamma-Fe2O3 core and non-stoichiometric shell. The nanoparticle surface layer has a great influence on their properties which is principally manifested in significant reduction of the magnetization and in a large increase in magnetic anisotropy. Magnetic moments do not saturate in fields up to 5 T, even at the lowest measured temperature, T = 5 K. The average magnetic particle diameter is changed from 1.3 to 1.8 nm with increasing magnetic field from 0 to 5 T which is noticeably smaller than the particle sizes measured by TEM. The estimated effective magnetic anisotropy constant value, K-eff = 2 x 10(5) J/m(3), is two orders of magnitude higher than in the bulk maghemite. Measurements of the longitudinal and transverse NMR relaxivity parameters on water diluted nanoparticle dispersions at 1.5 T gave the values r(1) = 0.028 mmol(-1) s(-1), r(2) = 0.050 mmol(-1) s(-1) and their ratio r(2)/r(1) = 1.8. Continuous increase of the T-1-weighted MRI signal intensity with increasing Fe concentration in the nanoparticle dispersions was observed which makes this ferrofluid to behave as a positive T-1 contrast agent. (C) 2017 Elsevier B.V. All rights reserved.", journal = "Current Applied Physics", title = "Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties", volume = "18", number = "2", pages = "141-149", doi = "10.1016/j.cap.2017.11.017" }
Babić-Stojić, B. S., Jokanović, V. R., Milivojević, D., Pozek, M., Jagličić, Z., Makovec, D., Jović Orsini, N., Marković, M., Arsikin, K. M.,& Paunović, V. G.. (2018). Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties. in Current Applied Physics, 18(2), 141-149. https://doi.org/10.1016/j.cap.2017.11.017
Babić-Stojić BS, Jokanović VR, Milivojević D, Pozek M, Jagličić Z, Makovec D, Jović Orsini N, Marković M, Arsikin KM, Paunović VG. Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties. in Current Applied Physics. 2018;18(2):141-149. doi:10.1016/j.cap.2017.11.017 .
Babić-Stojić, Branka S., Jokanović, Vukoman R., Milivojević, Dušan, Pozek, Miroslav, Jagličić, Zvonko, Makovec, Darko, Jović Orsini, Nataša, Marković, Mirjana, Arsikin, Katarina M., Paunović, Verica G., "Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties" in Current Applied Physics, 18, no. 2 (2018):141-149, https://doi.org/10.1016/j.cap.2017.11.017 . .