Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites
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2017
Authors
Malagurski, IvanaLević, Steva
Pantić, Milena
Matijašević, Danka
Mitrić, Miodrag
Pavlović, Vladimir B.
Dimitrijević-Branković, Suzana I.
Article (Published version)
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New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents agood strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved.
Keywords:
Zinc / Alginate / Nanocomposite / Biomineralization / Antimicrobial activitySource:
Carbohydrate Polymers, 2017, 165, 313-321Funding / projects:
- Synthesis, processing and applications of nanostructured multifunctional materials with defined properties (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45019)
- Directed synthesis, structure and properties of multifunctional materials (RS-MESTD-Basic Research (BR or ON)-172057)
DOI: 10.1016/j.carbpol.2017.02.064
ISSN: 0144-8617; 1879-1344
PubMed: 28363555
WoS: 000399261900035
Scopus: 2-s2.0-85013763459
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VinčaTY - JOUR AU - Malagurski, Ivana AU - Lević, Steva AU - Pantić, Milena AU - Matijašević, Danka AU - Mitrić, Miodrag AU - Pavlović, Vladimir B. AU - Dimitrijević-Branković, Suzana I. PY - 2017 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1508 AB - New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents agood strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved. T2 - Carbohydrate Polymers T1 - Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites VL - 165 SP - 313 EP - 321 DO - 10.1016/j.carbpol.2017.02.064 ER -
@article{ author = "Malagurski, Ivana and Lević, Steva and Pantić, Milena and Matijašević, Danka and Mitrić, Miodrag and Pavlović, Vladimir B. and Dimitrijević-Branković, Suzana I.", year = "2017", abstract = "New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents agood strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved.", journal = "Carbohydrate Polymers", title = "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites", volume = "165", pages = "313-321", doi = "10.1016/j.carbpol.2017.02.064" }
Malagurski, I., Lević, S., Pantić, M., Matijašević, D., Mitrić, M., Pavlović, V. B.,& Dimitrijević-Branković, S. I.. (2017). Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers, 165, 313-321. https://doi.org/10.1016/j.carbpol.2017.02.064
Malagurski I, Lević S, Pantić M, Matijašević D, Mitrić M, Pavlović VB, Dimitrijević-Branković SI. Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers. 2017;165:313-321. doi:10.1016/j.carbpol.2017.02.064 .
Malagurski, Ivana, Lević, Steva, Pantić, Milena, Matijašević, Danka, Mitrić, Miodrag, Pavlović, Vladimir B., Dimitrijević-Branković, Suzana I., "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites" in Carbohydrate Polymers, 165 (2017):313-321, https://doi.org/10.1016/j.carbpol.2017.02.064 . .