Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity
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2017
Authors
Nešić, AleksandraOnjia, Antonije E.
Davidović, Slađana Z.
Dimitrijević, Suzana I.
Errico, Maria Emanuela
Santagata, Gabriella
Malinconico, Mario
Article (Published version)
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In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices. (C) 2016 Elsevier ...Ltd. All rights reserved.
Keywords:
Pectin / Alginate / Zinc crosslinking / Antimicrobial filmsSource:
Carbohydrate Polymers, 2017, 157, 981-990Funding / projects:
- Advanced technologies for monitoring and environmental protection from chemical pollutants and radiation burden (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-43009)
- Application of biotechnological methods for sustainable exploitation of by-products of agro-industry (RS-MESTD-Technological Development (TD or TR)-31035)
- Ministry of Education, University and Research of the Republic of Italy [RS13MO4], National Technological Cluster of Ministry of University and Research (MIUR)
DOI: 10.1016/j.carbpol.2016.10.054
ISSN: 0144-8617; 1879-1344
PubMed: 27988017
WoS: 000391896800111
Scopus: 2-s2.0-85005978040
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VinčaTY - JOUR AU - Nešić, Aleksandra AU - Onjia, Antonije E. AU - Davidović, Slađana Z. AU - Dimitrijević, Suzana I. AU - Errico, Maria Emanuela AU - Santagata, Gabriella AU - Malinconico, Mario PY - 2017 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1385 AB - In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices. (C) 2016 Elsevier Ltd. All rights reserved. T2 - Carbohydrate Polymers T1 - Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity VL - 157 SP - 981 EP - 990 DO - 10.1016/j.carbpol.2016.10.054 ER -
@article{ author = "Nešić, Aleksandra and Onjia, Antonije E. and Davidović, Slađana Z. and Dimitrijević, Suzana I. and Errico, Maria Emanuela and Santagata, Gabriella and Malinconico, Mario", year = "2017", abstract = "In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices. (C) 2016 Elsevier Ltd. All rights reserved.", journal = "Carbohydrate Polymers", title = "Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity", volume = "157", pages = "981-990", doi = "10.1016/j.carbpol.2016.10.054" }
Nešić, A., Onjia, A. E., Davidović, S. Z., Dimitrijević, S. I., Errico, M. E., Santagata, G.,& Malinconico, M.. (2017). Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity. in Carbohydrate Polymers, 157, 981-990. https://doi.org/10.1016/j.carbpol.2016.10.054
Nešić A, Onjia AE, Davidović SZ, Dimitrijević SI, Errico ME, Santagata G, Malinconico M. Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity. in Carbohydrate Polymers. 2017;157:981-990. doi:10.1016/j.carbpol.2016.10.054 .
Nešić, Aleksandra, Onjia, Antonije E., Davidović, Slađana Z., Dimitrijević, Suzana I., Errico, Maria Emanuela, Santagata, Gabriella, Malinconico, Mario, "Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity" in Carbohydrate Polymers, 157 (2017):981-990, https://doi.org/10.1016/j.carbpol.2016.10.054 . .