Uncoupling of cardiac and respiratory rhythm in atrial fibrillation
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Platiša, Mirjana M.Bojić, Tijana
Pavlović, Siniša U.
Radovanovic, Nikola N.
Kalauzi, Aleksandar
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Rearranged origin of heart rhythm in patients with atrial fibrillation (AF) influences the regulation of the heart and consequently the respiratory rhythm, and the bidirectional interaction of these rhythms not documented. Hence, we examined coupling of the RR interval and the respiration (Resp) signal by coherence, Granger causality and the cross-sample entropy method of time series analysis in patients with AF and a healthy control group. In healthy subjects, the influence of respiration on cardiac rhythm was found as increased coherence at the breathing frequency (BF) range, significantly stronger interaction and synchrony from Resp to RR than from RR to Resp. On the contrary, in patients with AF, coherence at BF diminished, there were no causal interactions between signals in both directions, which resulted in equally great asynchrony between them. In AF, the absence of full functionality of the sinoatrial node, as an integrator of neural cardiac control, resulted in diminished vag...al modulation of heart periods and consequently impaired bidirectional cardio-respiratory interaction.
Keywords:
atrial fibrillation / cardio-respiratory coupling / coherence / cross-sample entropy / Granger causality / heart rate / respirationSource:
Biomedical Engineering / Biomedizinische Technik, 2016, 61, 6, 657-663Funding / projects:
- Development of new technology for production of red wine and diatery supplements reach with polyphenols with cardioprotective effects (RS-MESTD-Technological Development (TD or TR)-31020)
- Neurobiology of sleep in aging and disease - electroencephalographic markers and modeling in the estimation of disorder (RS-MESTD-Basic Research (BR or ON)-173022)
- An integral study to identify the regional genetic and environmental risk factors for the common noncommunicable diseases in the human population of Serbia - INGEMA_S (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41028)
DOI: 10.1515/bmt-2016-0057
ISSN: 0013-5585
PubMed: 27824611
WoS: 000389468000010
Scopus: 2-s2.0-85015741391
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VinčaTY - JOUR AU - Platiša, Mirjana M. AU - Bojić, Tijana AU - Pavlović, Siniša U. AU - Radovanovic, Nikola N. AU - Kalauzi, Aleksandar PY - 2016 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1332 AB - Rearranged origin of heart rhythm in patients with atrial fibrillation (AF) influences the regulation of the heart and consequently the respiratory rhythm, and the bidirectional interaction of these rhythms not documented. Hence, we examined coupling of the RR interval and the respiration (Resp) signal by coherence, Granger causality and the cross-sample entropy method of time series analysis in patients with AF and a healthy control group. In healthy subjects, the influence of respiration on cardiac rhythm was found as increased coherence at the breathing frequency (BF) range, significantly stronger interaction and synchrony from Resp to RR than from RR to Resp. On the contrary, in patients with AF, coherence at BF diminished, there were no causal interactions between signals in both directions, which resulted in equally great asynchrony between them. In AF, the absence of full functionality of the sinoatrial node, as an integrator of neural cardiac control, resulted in diminished vagal modulation of heart periods and consequently impaired bidirectional cardio-respiratory interaction. T2 - Biomedical Engineering / Biomedizinische Technik T1 - Uncoupling of cardiac and respiratory rhythm in atrial fibrillation VL - 61 IS - 6 SP - 657 EP - 663 DO - 10.1515/bmt-2016-0057 ER -
@article{ author = "Platiša, Mirjana M. and Bojić, Tijana and Pavlović, Siniša U. and Radovanovic, Nikola N. and Kalauzi, Aleksandar", year = "2016", abstract = "Rearranged origin of heart rhythm in patients with atrial fibrillation (AF) influences the regulation of the heart and consequently the respiratory rhythm, and the bidirectional interaction of these rhythms not documented. Hence, we examined coupling of the RR interval and the respiration (Resp) signal by coherence, Granger causality and the cross-sample entropy method of time series analysis in patients with AF and a healthy control group. In healthy subjects, the influence of respiration on cardiac rhythm was found as increased coherence at the breathing frequency (BF) range, significantly stronger interaction and synchrony from Resp to RR than from RR to Resp. On the contrary, in patients with AF, coherence at BF diminished, there were no causal interactions between signals in both directions, which resulted in equally great asynchrony between them. In AF, the absence of full functionality of the sinoatrial node, as an integrator of neural cardiac control, resulted in diminished vagal modulation of heart periods and consequently impaired bidirectional cardio-respiratory interaction.", journal = "Biomedical Engineering / Biomedizinische Technik", title = "Uncoupling of cardiac and respiratory rhythm in atrial fibrillation", volume = "61", number = "6", pages = "657-663", doi = "10.1515/bmt-2016-0057" }
Platiša, M. M., Bojić, T., Pavlović, S. U., Radovanovic, N. N.,& Kalauzi, A.. (2016). Uncoupling of cardiac and respiratory rhythm in atrial fibrillation. in Biomedical Engineering / Biomedizinische Technik, 61(6), 657-663. https://doi.org/10.1515/bmt-2016-0057
Platiša MM, Bojić T, Pavlović SU, Radovanovic NN, Kalauzi A. Uncoupling of cardiac and respiratory rhythm in atrial fibrillation. in Biomedical Engineering / Biomedizinische Technik. 2016;61(6):657-663. doi:10.1515/bmt-2016-0057 .
Platiša, Mirjana M., Bojić, Tijana, Pavlović, Siniša U., Radovanovic, Nikola N., Kalauzi, Aleksandar, "Uncoupling of cardiac and respiratory rhythm in atrial fibrillation" in Biomedical Engineering / Biomedizinische Technik, 61, no. 6 (2016):657-663, https://doi.org/10.1515/bmt-2016-0057 . .