Biological Aspects of Application of Nanomaterials in Tissue Engineering
Apstrakt
Millions of patients worldwide need surgery to repair or replace tissue that has been damaged through trauma or disease. To solve the problem of lost tissue, a major emphasis of tissue engineering (TE) is on tissue regeneration. Stem cells and highly porous biomaterials used as cell carriers (scaffolds) have an essential role in the production of new tissue by TE. The cellular component is important for the generation and establishment of the extracellular matrix, while a scaffold is necessary to determine the shape of the newly formed tissue and facilitate migration of cells into the desired location, as well as their growth and differentiation. This review describes the types, characteristics and classification of stem cells. Furthermore, it includes functional features of cell carriers - biocompatibility, biodegradability and mechanical properties of biomaterials used in developing state-of-the-an scaffolds for TE applications, as well as suitability for different tissues. Moreover,... it explains the importance of nanotechnology and defines the challenges and the purpose of future research in this rapidly advancing field.
Ključne reči:
tissue engineering / nanomaterials / scaffolds / stem cells / tissue regenerationIzvor:
Chemical Industry and Chemical Engineering Quarterly / CICEQ, 2016, 22, 2, 145-153Finansiranje / projekti:
- Biološki mehanizmi, nutritivni unos i status polinezasićenih masnih kiselina i folata: Unapređenje ishrane u Srbiji (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41030)
- Hemijsko i strukturno dizajniranje nanomaterijala za primenu u medicini i inženjerstvu tkiva (RS-MESTD-Basic Research (BR or ON)-172026)
DOI: 10.2298/CICEQ141231028M
ISSN: 1451-9372
WoS: 000384727700003
Scopus: 2-s2.0-84979777199
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Marković, Dejan AU - Karadzic, Ivana AU - Jokanović, Vukoman R. AU - Vukovic, Ana AU - Vučić, Vesna PY - 2016 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1258 AB - Millions of patients worldwide need surgery to repair or replace tissue that has been damaged through trauma or disease. To solve the problem of lost tissue, a major emphasis of tissue engineering (TE) is on tissue regeneration. Stem cells and highly porous biomaterials used as cell carriers (scaffolds) have an essential role in the production of new tissue by TE. The cellular component is important for the generation and establishment of the extracellular matrix, while a scaffold is necessary to determine the shape of the newly formed tissue and facilitate migration of cells into the desired location, as well as their growth and differentiation. This review describes the types, characteristics and classification of stem cells. Furthermore, it includes functional features of cell carriers - biocompatibility, biodegradability and mechanical properties of biomaterials used in developing state-of-the-an scaffolds for TE applications, as well as suitability for different tissues. Moreover, it explains the importance of nanotechnology and defines the challenges and the purpose of future research in this rapidly advancing field. T2 - Chemical Industry and Chemical Engineering Quarterly / CICEQ T1 - Biological Aspects of Application of Nanomaterials in Tissue Engineering VL - 22 IS - 2 SP - 145 EP - 153 DO - 10.2298/CICEQ141231028M ER -
@article{ author = "Marković, Dejan and Karadzic, Ivana and Jokanović, Vukoman R. and Vukovic, Ana and Vučić, Vesna", year = "2016", abstract = "Millions of patients worldwide need surgery to repair or replace tissue that has been damaged through trauma or disease. To solve the problem of lost tissue, a major emphasis of tissue engineering (TE) is on tissue regeneration. Stem cells and highly porous biomaterials used as cell carriers (scaffolds) have an essential role in the production of new tissue by TE. The cellular component is important for the generation and establishment of the extracellular matrix, while a scaffold is necessary to determine the shape of the newly formed tissue and facilitate migration of cells into the desired location, as well as their growth and differentiation. This review describes the types, characteristics and classification of stem cells. Furthermore, it includes functional features of cell carriers - biocompatibility, biodegradability and mechanical properties of biomaterials used in developing state-of-the-an scaffolds for TE applications, as well as suitability for different tissues. Moreover, it explains the importance of nanotechnology and defines the challenges and the purpose of future research in this rapidly advancing field.", journal = "Chemical Industry and Chemical Engineering Quarterly / CICEQ", title = "Biological Aspects of Application of Nanomaterials in Tissue Engineering", volume = "22", number = "2", pages = "145-153", doi = "10.2298/CICEQ141231028M" }
Marković, D., Karadzic, I., Jokanović, V. R., Vukovic, A.,& Vučić, V.. (2016). Biological Aspects of Application of Nanomaterials in Tissue Engineering. in Chemical Industry and Chemical Engineering Quarterly / CICEQ, 22(2), 145-153. https://doi.org/10.2298/CICEQ141231028M
Marković D, Karadzic I, Jokanović VR, Vukovic A, Vučić V. Biological Aspects of Application of Nanomaterials in Tissue Engineering. in Chemical Industry and Chemical Engineering Quarterly / CICEQ. 2016;22(2):145-153. doi:10.2298/CICEQ141231028M .
Marković, Dejan, Karadzic, Ivana, Jokanović, Vukoman R., Vukovic, Ana, Vučić, Vesna, "Biological Aspects of Application of Nanomaterials in Tissue Engineering" in Chemical Industry and Chemical Engineering Quarterly / CICEQ, 22, no. 2 (2016):145-153, https://doi.org/10.2298/CICEQ141231028M . .