The effect of silver nanoparticle shape on the physicochemical properties of a poly(n-isopropylacrylamide) hydrogel nanocomposites
Uticaj oblika nanočestica srebra na fizičkohemijska svojstva poli(n-izopropilakrilamid) hidrogel nanokompozita
2023
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Spasojević, JelenaVukoje, Ivana
Nikolić, Nikolina
Tadić, Julijana
Milošević, Milica
Vodnik, Vesna
Radosavljević, Aleksandra
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Hydrogels have unique properties and many potential applications, particularly in medicine and biotechnology. Gel porosity and swelling properties, stability, and biocompatibility are charac-teristics that are widely variable and easily adjusted. Stimuli-responsive or intelligent hydrogels are a class of thesematerials that shows a significant response to small changes in the surrounding environment. Poly(N-isopropylacrylamide) (PNiPAAm) is the best-known thermosensitive polymer with a well-defined volume phase transition temperature (VPTT) around 32C. On theother hand, silver nanoparticles (AgNPs) have been the subject of intense interest due to their size-dependent optical, catalytic, and electronic properties as well as remarkable antimicrobial potential. Within the last decade, scientists have demonstrated that anisotropic AgNPs can be synthesized in a controlled manner and that these materials exhibit distinctively dif...ferent physicochemical properties from their spherical counterparts. A significant challenge that scientists face is establishing how thesenanoparticles can be used in a wider spectrum of practical applications. Therefore, we pre-sent a simple, straightforward two-step synthesis of AgNPs/PNiPAAm hydrogel nanocomposites that includes the chemical formation of both spherical and triangular AgNPs, followed by gamma irradiation-induced PNiPAAm crosslinking in the presence of nanoparticles. The gamma irradia-tion technique merges sterilization and synthesis in a single technological step, optimizing the pro-cess and opening up a wide range of innovative biomedical applications. The formation of stable and uniformly distributed AgNPs in the polymer was confirmed by UV-VIS spectroscopy, while the network porous sponge-like structure was observed by SEM analysis. Physicochemical characteri-zation was performed by examining the swelling and deswelling processes in water at 25C and 48C, respectively. In addition, AgNPs were shown to have an effect on VPTT values. Our main goal is to investigate how different morphologies of AgNPs affect the physicochemicalproperties of nanocomposite samples, considering the potential applications and the ongoing need for the wide-spread use of biocompatible materials
Hidrogelovi su materijali koji poseduju specifičnu poroznost, stabilnost, biokompatibilnost i sposobnost apsorpcije okolne tečnosti, kao i svojstva koja su promenljiva i lako podesiva širokom spektru primena, naročito u oblasti medicine i biotehnologije. Posebno je interesantna oblast “inteligentnih“ hidrogelova, odnosno materijala koji reaguju na spoljašnje stimulanse i pokazuju značajanu fizičku ili hemijsku promenu pri malim promenama u okruženju. Poli(N-izopropilakrilamid) (PNiPAAm) je najpoznatiji termosenzitivni polimer sa jasno definisanom temperaturom faznog prelaza (VPTT) od oko 32°C. S druge strane, nanočestice srebra (AgNPs) poseduju optička, katalitička i električna svojstva koja se mogu modifikovati promenom njihove veličine i oblika a imaju i izražen antibakterijski potencijal, pa su stoga, poslednjih decenija intenzivno proučavane. Pokazano je da se anizotropne nanočestice srebra mogu kontrolisano sintetisati sa fizičkohemijskim svojstvima različitim od sfernih analoga, ...pri čemu su značajna istraživanja usmerena na njihovu praktičnu primenu. Zbog svega navedenog, u okviru ovog istraživanja biće izvedena jednostavna dvostepena sinteza AgNPs/PNiPAAm hidrogel nanokompozita koja uključuje hemijsko formiranje sfernih i trouglastih AgNPs u prvom koraku, a zatim gama-indukovano umrežavanje NiPAAm-a u prisustvu ovih AgNPs. Tehnika gama zračenja objedinjuje sterilizaciju i sintezu u jednom tehnološkom koraku čime se proces optimizuje i otvara širok spektar inovativnih biomedicinskih primena. Formiranje stabilnih i uniformno distribuiranih AgNPs unutar matrice hidrogela potvrđeno je UV-Vis spektroskopijom, a porozna sunđerasta struktura polimerne mreže SEM analizom. Fizičkohemijska karakterizacija izvršena je i ispitivanjem procesa bubrenja i kontrahovanja u vodi na 25°C i 48°C, redom. Pored toga, pokazano je da prisustvo AgNPs utiče na vrednosti temperature faznog prelaza polimera. Osnovni cilj ovog istraživanja je ispitivanje uticaja različite morfologije AgNPs na fizičkohemijska svojstva sintetisanih nanokompozita, imajući u vidu njihovu potencijalnu primenu i stalnu potrebu za širokom upotrebom biokompatibilnih materijala.
Keywords:
Hydrogel nanocomposites / silver nanoparticles / VPTT / swelling properties / Hidrogel nanokompoziti / nanočestice srebra / fazni prelaz / svojstva bubrenjaSource:
36. Međunarodni kongres o procesnoj industriji - PROCESING ′23 : zbornik radova, 2023, 197-206Publisher:
- Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS) : Društvo za procesnu tehniku
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200017 (University of Belgrade, Institute of Nuclear Sciences 'Vinča', Belgrade-Vinča) (RS-MESTD-inst-2020-200017)
Note:
- 36. Međunarodni kongres o procesnoj industriji - PROCESING ′23 : zbornik radova ; 1-2. jun, Šabac
Institution/Community
VinčaTY - CONF AU - Spasojević, Jelena AU - Vukoje, Ivana AU - Nikolić, Nikolina AU - Tadić, Julijana AU - Milošević, Milica AU - Vodnik, Vesna AU - Radosavljević, Aleksandra PY - 2023 UR - https://vinar.vin.bg.ac.rs/handle/123456789/11595 AB - Hydrogels have unique properties and many potential applications, particularly in medicine and biotechnology. Gel porosity and swelling properties, stability, and biocompatibility are charac-teristics that are widely variable and easily adjusted. Stimuli-responsive or intelligent hydrogels are a class of thesematerials that shows a significant response to small changes in the surrounding environment. Poly(N-isopropylacrylamide) (PNiPAAm) is the best-known thermosensitive polymer with a well-defined volume phase transition temperature (VPTT) around 32C. On theother hand, silver nanoparticles (AgNPs) have been the subject of intense interest due to their size-dependent optical, catalytic, and electronic properties as well as remarkable antimicrobial potential. Within the last decade, scientists have demonstrated that anisotropic AgNPs can be synthesized in a controlled manner and that these materials exhibit distinctively different physicochemical properties from their spherical counterparts. A significant challenge that scientists face is establishing how thesenanoparticles can be used in a wider spectrum of practical applications. Therefore, we pre-sent a simple, straightforward two-step synthesis of AgNPs/PNiPAAm hydrogel nanocomposites that includes the chemical formation of both spherical and triangular AgNPs, followed by gamma irradiation-induced PNiPAAm crosslinking in the presence of nanoparticles. The gamma irradia-tion technique merges sterilization and synthesis in a single technological step, optimizing the pro-cess and opening up a wide range of innovative biomedical applications. The formation of stable and uniformly distributed AgNPs in the polymer was confirmed by UV-VIS spectroscopy, while the network porous sponge-like structure was observed by SEM analysis. Physicochemical characteri-zation was performed by examining the swelling and deswelling processes in water at 25C and 48C, respectively. In addition, AgNPs were shown to have an effect on VPTT values. Our main goal is to investigate how different morphologies of AgNPs affect the physicochemicalproperties of nanocomposite samples, considering the potential applications and the ongoing need for the wide-spread use of biocompatible materials AB - Hidrogelovi su materijali koji poseduju specifičnu poroznost, stabilnost, biokompatibilnost i sposobnost apsorpcije okolne tečnosti, kao i svojstva koja su promenljiva i lako podesiva širokom spektru primena, naročito u oblasti medicine i biotehnologije. Posebno je interesantna oblast “inteligentnih“ hidrogelova, odnosno materijala koji reaguju na spoljašnje stimulanse i pokazuju značajanu fizičku ili hemijsku promenu pri malim promenama u okruženju. Poli(N-izopropilakrilamid) (PNiPAAm) je najpoznatiji termosenzitivni polimer sa jasno definisanom temperaturom faznog prelaza (VPTT) od oko 32°C. S druge strane, nanočestice srebra (AgNPs) poseduju optička, katalitička i električna svojstva koja se mogu modifikovati promenom njihove veličine i oblika a imaju i izražen antibakterijski potencijal, pa su stoga, poslednjih decenija intenzivno proučavane. Pokazano je da se anizotropne nanočestice srebra mogu kontrolisano sintetisati sa fizičkohemijskim svojstvima različitim od sfernih analoga, pri čemu su značajna istraživanja usmerena na njihovu praktičnu primenu. Zbog svega navedenog, u okviru ovog istraživanja biće izvedena jednostavna dvostepena sinteza AgNPs/PNiPAAm hidrogel nanokompozita koja uključuje hemijsko formiranje sfernih i trouglastih AgNPs u prvom koraku, a zatim gama-indukovano umrežavanje NiPAAm-a u prisustvu ovih AgNPs. Tehnika gama zračenja objedinjuje sterilizaciju i sintezu u jednom tehnološkom koraku čime se proces optimizuje i otvara širok spektar inovativnih biomedicinskih primena. Formiranje stabilnih i uniformno distribuiranih AgNPs unutar matrice hidrogela potvrđeno je UV-Vis spektroskopijom, a porozna sunđerasta struktura polimerne mreže SEM analizom. Fizičkohemijska karakterizacija izvršena je i ispitivanjem procesa bubrenja i kontrahovanja u vodi na 25°C i 48°C, redom. Pored toga, pokazano je da prisustvo AgNPs utiče na vrednosti temperature faznog prelaza polimera. Osnovni cilj ovog istraživanja je ispitivanje uticaja različite morfologije AgNPs na fizičkohemijska svojstva sintetisanih nanokompozita, imajući u vidu njihovu potencijalnu primenu i stalnu potrebu za širokom upotrebom biokompatibilnih materijala. PB - Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS) : Društvo za procesnu tehniku C3 - 36. Međunarodni kongres o procesnoj industriji - PROCESING ′23 : zbornik radova T1 - The effect of silver nanoparticle shape on the physicochemical properties of a poly(n-isopropylacrylamide) hydrogel nanocomposites T1 - Uticaj oblika nanočestica srebra na fizičkohemijska svojstva poli(n-izopropilakrilamid) hidrogel nanokompozita SP - 197 EP - 206 DO - 10.24094/ptk.023.197 ER -
@conference{ author = "Spasojević, Jelena and Vukoje, Ivana and Nikolić, Nikolina and Tadić, Julijana and Milošević, Milica and Vodnik, Vesna and Radosavljević, Aleksandra", year = "2023", abstract = "Hydrogels have unique properties and many potential applications, particularly in medicine and biotechnology. Gel porosity and swelling properties, stability, and biocompatibility are charac-teristics that are widely variable and easily adjusted. Stimuli-responsive or intelligent hydrogels are a class of thesematerials that shows a significant response to small changes in the surrounding environment. Poly(N-isopropylacrylamide) (PNiPAAm) is the best-known thermosensitive polymer with a well-defined volume phase transition temperature (VPTT) around 32C. On theother hand, silver nanoparticles (AgNPs) have been the subject of intense interest due to their size-dependent optical, catalytic, and electronic properties as well as remarkable antimicrobial potential. Within the last decade, scientists have demonstrated that anisotropic AgNPs can be synthesized in a controlled manner and that these materials exhibit distinctively different physicochemical properties from their spherical counterparts. A significant challenge that scientists face is establishing how thesenanoparticles can be used in a wider spectrum of practical applications. Therefore, we pre-sent a simple, straightforward two-step synthesis of AgNPs/PNiPAAm hydrogel nanocomposites that includes the chemical formation of both spherical and triangular AgNPs, followed by gamma irradiation-induced PNiPAAm crosslinking in the presence of nanoparticles. The gamma irradia-tion technique merges sterilization and synthesis in a single technological step, optimizing the pro-cess and opening up a wide range of innovative biomedical applications. The formation of stable and uniformly distributed AgNPs in the polymer was confirmed by UV-VIS spectroscopy, while the network porous sponge-like structure was observed by SEM analysis. Physicochemical characteri-zation was performed by examining the swelling and deswelling processes in water at 25C and 48C, respectively. In addition, AgNPs were shown to have an effect on VPTT values. Our main goal is to investigate how different morphologies of AgNPs affect the physicochemicalproperties of nanocomposite samples, considering the potential applications and the ongoing need for the wide-spread use of biocompatible materials, Hidrogelovi su materijali koji poseduju specifičnu poroznost, stabilnost, biokompatibilnost i sposobnost apsorpcije okolne tečnosti, kao i svojstva koja su promenljiva i lako podesiva širokom spektru primena, naročito u oblasti medicine i biotehnologije. Posebno je interesantna oblast “inteligentnih“ hidrogelova, odnosno materijala koji reaguju na spoljašnje stimulanse i pokazuju značajanu fizičku ili hemijsku promenu pri malim promenama u okruženju. Poli(N-izopropilakrilamid) (PNiPAAm) je najpoznatiji termosenzitivni polimer sa jasno definisanom temperaturom faznog prelaza (VPTT) od oko 32°C. S druge strane, nanočestice srebra (AgNPs) poseduju optička, katalitička i električna svojstva koja se mogu modifikovati promenom njihove veličine i oblika a imaju i izražen antibakterijski potencijal, pa su stoga, poslednjih decenija intenzivno proučavane. Pokazano je da se anizotropne nanočestice srebra mogu kontrolisano sintetisati sa fizičkohemijskim svojstvima različitim od sfernih analoga, pri čemu su značajna istraživanja usmerena na njihovu praktičnu primenu. Zbog svega navedenog, u okviru ovog istraživanja biće izvedena jednostavna dvostepena sinteza AgNPs/PNiPAAm hidrogel nanokompozita koja uključuje hemijsko formiranje sfernih i trouglastih AgNPs u prvom koraku, a zatim gama-indukovano umrežavanje NiPAAm-a u prisustvu ovih AgNPs. Tehnika gama zračenja objedinjuje sterilizaciju i sintezu u jednom tehnološkom koraku čime se proces optimizuje i otvara širok spektar inovativnih biomedicinskih primena. Formiranje stabilnih i uniformno distribuiranih AgNPs unutar matrice hidrogela potvrđeno je UV-Vis spektroskopijom, a porozna sunđerasta struktura polimerne mreže SEM analizom. Fizičkohemijska karakterizacija izvršena je i ispitivanjem procesa bubrenja i kontrahovanja u vodi na 25°C i 48°C, redom. Pored toga, pokazano je da prisustvo AgNPs utiče na vrednosti temperature faznog prelaza polimera. Osnovni cilj ovog istraživanja je ispitivanje uticaja različite morfologije AgNPs na fizičkohemijska svojstva sintetisanih nanokompozita, imajući u vidu njihovu potencijalnu primenu i stalnu potrebu za širokom upotrebom biokompatibilnih materijala.", publisher = "Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS) : Društvo za procesnu tehniku", journal = "36. Međunarodni kongres o procesnoj industriji - PROCESING ′23 : zbornik radova", title = "The effect of silver nanoparticle shape on the physicochemical properties of a poly(n-isopropylacrylamide) hydrogel nanocomposites, Uticaj oblika nanočestica srebra na fizičkohemijska svojstva poli(n-izopropilakrilamid) hidrogel nanokompozita", pages = "197-206", doi = "10.24094/ptk.023.197" }
Spasojević, J., Vukoje, I., Nikolić, N., Tadić, J., Milošević, M., Vodnik, V.,& Radosavljević, A.. (2023). The effect of silver nanoparticle shape on the physicochemical properties of a poly(n-isopropylacrylamide) hydrogel nanocomposites. in 36. Međunarodni kongres o procesnoj industriji - PROCESING ′23 : zbornik radova Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS) : Društvo za procesnu tehniku., 197-206. https://doi.org/10.24094/ptk.023.197
Spasojević J, Vukoje I, Nikolić N, Tadić J, Milošević M, Vodnik V, Radosavljević A. The effect of silver nanoparticle shape on the physicochemical properties of a poly(n-isopropylacrylamide) hydrogel nanocomposites. in 36. Međunarodni kongres o procesnoj industriji - PROCESING ′23 : zbornik radova. 2023;:197-206. doi:10.24094/ptk.023.197 .
Spasojević, Jelena, Vukoje, Ivana, Nikolić, Nikolina, Tadić, Julijana, Milošević, Milica, Vodnik, Vesna, Radosavljević, Aleksandra, "The effect of silver nanoparticle shape on the physicochemical properties of a poly(n-isopropylacrylamide) hydrogel nanocomposites" in 36. Međunarodni kongres o procesnoj industriji - PROCESING ′23 : zbornik radova (2023):197-206, https://doi.org/10.24094/ptk.023.197 . .