Prikaz osnovnih podataka o dokumentu
Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs
dc.creator | Mačvanin, Mirjana | |
dc.creator | Gluvić, Zoran | |
dc.creator | Radovanović, Jelena | |
dc.creator | Essack, Magbubah | |
dc.creator | Gao, Xin | |
dc.creator | Isenović, Esma R. | |
dc.date.accessioned | 2023-04-03T08:55:38Z | |
dc.date.available | 2023-04-03T08:55:38Z | |
dc.date.issued | 2023 | |
dc.identifier.issn | 1664-2392 | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/10774 | |
dc.description.abstract | Diabetes mellitus (DM) is on the rise, necessitating the development of novel therapeutic and preventive strategies to mitigate the disease’s debilitating effects. Diabetic cardiomyopathy (DCMP) is among the leading causes of morbidity and mortality in diabetic patients globally. DCMP manifests as cardiomyocyte hypertrophy, apoptosis, and myocardial interstitial fibrosis before progressing to heart failure. Evidence suggests that non-coding RNAs, such as long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), regulate diabetic cardiomyopathy-related processes such as insulin resistance, cardiomyocyte apoptosis and inflammation, emphasizing their heart-protective effects. This paper reviewed the literature data from animal and human studies on the non-trivial roles of miRNAs and lncRNAs in the context of DCMP in diabetes and demonstrated their future potential in DCMP treatment in diabetic patients. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200017/RS// | |
dc.relation | King Abdullah University of Science and Technology (KAUST) - [Grant awards No. BAS/1/1624-01-01, FCC/1/1976-20-01, FCC/1/1976-26-01 and No#OSR 4129] | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Frontiers in Endocrinology | |
dc.subject | diabetes | en |
dc.subject | cardiomyopathy | en |
dc.subject | microRNAs | en |
dc.subject | long non-coding RNAs | en |
dc.subject | therapeutic application | en |
dc.title | Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs | en |
dc.type | article | en |
dc.rights.license | BY | |
dc.citation.volume | 14 | |
dc.identifier.doi | 10.3389/fendo.2023.1124613 | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-85150518182 | |
dc.identifier.fulltext | http://vinar.vin.bg.ac.rs/bitstream/id/28493/fendo-14-1124613.pdf |
Dokumenti
Ovaj dokument se pojavljuje u sledećim kolekcijama
-
080 - Laboratorija za radiobiologiju i molekularnu genetiku
Department of Radiobiology and Molecular Genetics -
Radovi istraživača
Researchers' publications