Biomedical Potential of mTOR Modulation by Nanoparticles
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2016
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Modulation of the mammalian target of rapamycin (mTOR), the principal regulator of cellular homeostasis, underlies the biological effects of engineered nanoparticles, including regulation of cell death/survival and metabolic responses. Understanding the mechanisms and biological actions of nanoparticle-mediated mTOR modulation may help in developing safe and efficient nano therapeutics to fight human disease.
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Trends in Biotechnology, 2016, 34, 5, 349-353Funding / projects:
- CIHR
DOI: 10.1016/j.tibtech.2016.01.005
ISSN: 0167-7799
PubMed: 26900005
WoS: 000375810800002
Scopus: 2-s2.0-84969335435
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VinčaTY - JOUR AU - Hulea, Laura AU - Marković, Zoran M. AU - Topisirović, Ivan AU - Simmet, Thomas AU - Trajković, Vladimir S. PY - 2016 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1071 AB - Modulation of the mammalian target of rapamycin (mTOR), the principal regulator of cellular homeostasis, underlies the biological effects of engineered nanoparticles, including regulation of cell death/survival and metabolic responses. Understanding the mechanisms and biological actions of nanoparticle-mediated mTOR modulation may help in developing safe and efficient nano therapeutics to fight human disease. T2 - Trends in Biotechnology T1 - Biomedical Potential of mTOR Modulation by Nanoparticles VL - 34 IS - 5 SP - 349 EP - 353 DO - 10.1016/j.tibtech.2016.01.005 ER -
@article{ author = "Hulea, Laura and Marković, Zoran M. and Topisirović, Ivan and Simmet, Thomas and Trajković, Vladimir S.", year = "2016", abstract = "Modulation of the mammalian target of rapamycin (mTOR), the principal regulator of cellular homeostasis, underlies the biological effects of engineered nanoparticles, including regulation of cell death/survival and metabolic responses. Understanding the mechanisms and biological actions of nanoparticle-mediated mTOR modulation may help in developing safe and efficient nano therapeutics to fight human disease.", journal = "Trends in Biotechnology", title = "Biomedical Potential of mTOR Modulation by Nanoparticles", volume = "34", number = "5", pages = "349-353", doi = "10.1016/j.tibtech.2016.01.005" }
Hulea, L., Marković, Z. M., Topisirović, I., Simmet, T.,& Trajković, V. S.. (2016). Biomedical Potential of mTOR Modulation by Nanoparticles. in Trends in Biotechnology, 34(5), 349-353. https://doi.org/10.1016/j.tibtech.2016.01.005
Hulea L, Marković ZM, Topisirović I, Simmet T, Trajković VS. Biomedical Potential of mTOR Modulation by Nanoparticles. in Trends in Biotechnology. 2016;34(5):349-353. doi:10.1016/j.tibtech.2016.01.005 .
Hulea, Laura, Marković, Zoran M., Topisirović, Ivan, Simmet, Thomas, Trajković, Vladimir S., "Biomedical Potential of mTOR Modulation by Nanoparticles" in Trends in Biotechnology, 34, no. 5 (2016):349-353, https://doi.org/10.1016/j.tibtech.2016.01.005 . .