Organophosphate Pesticides and Human Health: Current Knowledge and Future Prospects
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Although an extensive legal framework regulates the development of organophosphate pesticides (OP), serious concerns have been raised considering human health risks resulting from consumption and acute or/and chronic exposure. Most pesticides and their residues are toxic to both the environment and humans, so international and national regulatory bodies have been established to control and enforce pesticide regulations and the maximum concentrations of residues in food and feed that are considered safe for humans. However, excessive pesticide application increases the risk of combined exposures to multiple residues that may lead to serious cumulative toxicity and adverse effects on human health. The health hazards can range from short-term to chronic conditions. For most of the OPs, toxicological data are collected from numerous studies covering a wide range of toxicological endpoints; however, the risk of health hazards due to pesticide exposure depends not only on how toxic the compo...unds are but also on the dose level at which harmful effects might be observed, and the frequency, timing and levels of exposure. This chapter presents the current state of knowledge and future perspectives regarding OPs use, regulations, routes of exposure, and the concomitant impacts on human health. © 2022 Nova Science Publishers, Inc.
Ključne reči:
future prospects / human health / organophosphate pesticidesIzvor:
Organophosphates: Detection, Exposure and Occurrence. Volume 1: Impact on Health and the Natural Environment, 2022, 1-26Institucija/grupa
VinčaTY - CHAP AU - Petrović, Sandra PY - 2022 UR - https://vinar.vin.bg.ac.rs/handle/123456789/10458 AB - Although an extensive legal framework regulates the development of organophosphate pesticides (OP), serious concerns have been raised considering human health risks resulting from consumption and acute or/and chronic exposure. Most pesticides and their residues are toxic to both the environment and humans, so international and national regulatory bodies have been established to control and enforce pesticide regulations and the maximum concentrations of residues in food and feed that are considered safe for humans. However, excessive pesticide application increases the risk of combined exposures to multiple residues that may lead to serious cumulative toxicity and adverse effects on human health. The health hazards can range from short-term to chronic conditions. For most of the OPs, toxicological data are collected from numerous studies covering a wide range of toxicological endpoints; however, the risk of health hazards due to pesticide exposure depends not only on how toxic the compounds are but also on the dose level at which harmful effects might be observed, and the frequency, timing and levels of exposure. This chapter presents the current state of knowledge and future perspectives regarding OPs use, regulations, routes of exposure, and the concomitant impacts on human health. © 2022 Nova Science Publishers, Inc. T2 - Organophosphates: Detection, Exposure and Occurrence. Volume 1: Impact on Health and the Natural Environment T1 - Organophosphate Pesticides and Human Health: Current Knowledge and Future Prospects SP - 1 EP - 26 UR - https://hdl.handle.net/21.15107/rcub_vinar_10458 ER -
@inbook{ author = "Petrović, Sandra", year = "2022", abstract = "Although an extensive legal framework regulates the development of organophosphate pesticides (OP), serious concerns have been raised considering human health risks resulting from consumption and acute or/and chronic exposure. Most pesticides and their residues are toxic to both the environment and humans, so international and national regulatory bodies have been established to control and enforce pesticide regulations and the maximum concentrations of residues in food and feed that are considered safe for humans. However, excessive pesticide application increases the risk of combined exposures to multiple residues that may lead to serious cumulative toxicity and adverse effects on human health. The health hazards can range from short-term to chronic conditions. For most of the OPs, toxicological data are collected from numerous studies covering a wide range of toxicological endpoints; however, the risk of health hazards due to pesticide exposure depends not only on how toxic the compounds are but also on the dose level at which harmful effects might be observed, and the frequency, timing and levels of exposure. This chapter presents the current state of knowledge and future perspectives regarding OPs use, regulations, routes of exposure, and the concomitant impacts on human health. © 2022 Nova Science Publishers, Inc.", journal = "Organophosphates: Detection, Exposure and Occurrence. Volume 1: Impact on Health and the Natural Environment", booktitle = "Organophosphate Pesticides and Human Health: Current Knowledge and Future Prospects", pages = "1-26", url = "https://hdl.handle.net/21.15107/rcub_vinar_10458" }
Petrović, S.. (2022). Organophosphate Pesticides and Human Health: Current Knowledge and Future Prospects. in Organophosphates: Detection, Exposure and Occurrence. Volume 1: Impact on Health and the Natural Environment, 1-26. https://hdl.handle.net/21.15107/rcub_vinar_10458
Petrović S. Organophosphate Pesticides and Human Health: Current Knowledge and Future Prospects. in Organophosphates: Detection, Exposure and Occurrence. Volume 1: Impact on Health and the Natural Environment. 2022;:1-26. https://hdl.handle.net/21.15107/rcub_vinar_10458 .
Petrović, Sandra, "Organophosphate Pesticides and Human Health: Current Knowledge and Future Prospects" in Organophosphates: Detection, Exposure and Occurrence. Volume 1: Impact on Health and the Natural Environment (2022):1-26, https://hdl.handle.net/21.15107/rcub_vinar_10458 .